Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50029372 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283886
(18-hydroxy-3-methoxy-2-methyl-4-methylamino-(2R,3S...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4[C@@H](O)NC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27+,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283895
(3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-1,7...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)[N+](C)(C)C Show InChI InChI=1S/C30H30N4O3/c1-30-28(36-5)21(34(2,3)4)14-22(37-30)32-19-12-8-6-10-16(19)24-25-18(15-31-29(25)35)23-17-11-7-9-13-20(17)33(30)27(23)26(24)32/h6-13,21-22,28H,14-15H2,1-5H3/p+1/t21-,22-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283891
(2-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)CC(O)=O Show InChI InChI=1S/C30H28N4O5/c1-30-28(38-3)20(32(2)14-22(35)36)12-21(39-30)33-18-10-6-4-8-15(18)24-25-17(13-31-29(25)37)23-16-9-5-7-11-19(16)34(30)27(23)26(24)33/h4-11,20-21,28H,12-14H2,1-3H3,(H,31,37)(H,35,36)/t20-,21-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283899
(CHEMBL340611 | ethyl[3-methoxy-2-methyl-16-oxo-(2R...)Show SMILES CC[N+](C)(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C31H32N4O3/c1-6-35(3,4)22-15-23-33-20-13-9-7-11-17(20)25-26-19(16-32-30(26)36)24-18-12-8-10-14-21(18)34(28(24)27(25)33)31(2,38-23)29(22)37-5/h7-14,22-23,29H,6,15-16H2,1-5H3/p+1/t22-,23-,29-,31+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM2579
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283888
(4-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C36H30N4O6/c1-36-32(45-3)25(38(2)34(42)18-12-14-19(15-13-18)35(43)44)16-26(46-36)39-23-10-6-4-8-20(23)28-29-22(17-37-33(29)41)27-21-9-5-7-11-24(21)40(36)31(27)30(28)39/h4-15,25-26,32H,16-17H2,1-3H3,(H,37,41)(H,43,44)/t25-,26-,32-,36+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283892
(3-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)CCC(O)=O Show InChI InChI=1S/C32H30N4O6/c1-32-30(41-3)21(34(2)22(37)12-13-24(38)39)14-23(42-32)35-19-10-6-4-8-16(19)26-27-18(15-33-31(27)40)25-17-9-5-7-11-20(17)36(32)29(25)28(26)35/h4-11,21,23,30H,12-15H2,1-3H3,(H,33,40)(H,38,39)/t21-,23-,30-,32+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283901
(CHEMBL335931 | Staurosporine derivative)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)CNC(=O)OC(C)(C)C Show InChI InChI=1S/C35H37N5O6/c1-34(2,3)46-33(43)37-17-24(41)38(5)23-15-25-39-21-13-9-7-11-18(21)27-28-20(16-36-32(28)42)26-19-12-8-10-14-22(19)40(30(26)29(27)39)35(4,45-25)31(23)44-6/h7-14,23,25,31H,15-17H2,1-6H3,(H,36,42)(H,37,43)/t23-,25-,31-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283894
(3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H24N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,29H,12H2,1-3H3,(H,30,33,34)/t15-,18-,25-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283892
(3-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)CCC(O)=O Show InChI InChI=1S/C32H30N4O6/c1-32-30(41-3)21(34(2)22(37)12-13-24(38)39)14-23(42-32)35-19-10-6-4-8-16(19)26-27-18(15-33-31(27)40)25-17-9-5-7-11-20(17)36(32)29(25)28(26)35/h4-11,21,23,30H,12-15H2,1-3H3,(H,33,40)(H,38,39)/t21-,23-,30-,32+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283909
(1N-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)CN Show InChI InChI=1S/C30H29N5O4/c1-30-28(38-3)20(33(2)21(36)13-31)12-22(39-30)34-18-10-6-4-8-15(18)24-25-17(14-32-29(25)37)23-16-9-5-7-11-19(16)35(30)27(23)26(24)34/h4-11,20,22,28H,12-14,31H2,1-3H3,(H,32,37)/t20-,22-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283900
(4-ethyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S,...)Show SMILES CCN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C30H30N4O3/c1-5-32(3)21-14-22-33-19-12-8-6-10-16(19)24-25-18(15-31-29(25)35)23-17-11-7-9-13-20(17)34(27(23)26(24)33)30(2,37-22)28(21)36-4/h6-13,21-22,28H,5,14-15H2,1-4H3,(H,31,35)/t21-,22-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283903
(18-hydroxy-5-methoxy-6-methyl-4-methylamino-(2S,4S...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4C(=O)N[C@@H](O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25-26,29,33H,12H2,1-3H3,(H,30,34)/t15-,18-,25-,26-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283900
(4-ethyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S,...)Show SMILES CCN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C30H30N4O3/c1-5-32(3)21-14-22-33-19-12-8-6-10-16(19)24-25-18(15-31-29(25)35)23-17-11-7-9-13-20(17)34(27(23)26(24)33)30(2,37-22)28(21)36-4/h6-13,21-22,28H,5,14-15H2,1-4H3,(H,31,35)/t21-,22-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM2579
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283886
(18-hydroxy-3-methoxy-2-methyl-4-methylamino-(2R,3S...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4[C@@H](O)NC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27+,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283894
(3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H24N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,29H,12H2,1-3H3,(H,30,33,34)/t15-,18-,25-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM31094
(PKC-412 | cid_24202429)Show SMILES [H][C@@]12C[C@@H]([C@H](OC)[C@@](C)(O1)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 |TLB:11:10:9:4.3.2,17:33:9:4.3.2,THB:24:32:9:4.3.2,5:4:9:10.31.33.32,30:31:9:4.3.2| Show InChI InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283902
(4-benzyl(methyl)amino-3-methoxy-2-methyl-(2R,3S,4S...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)Cc1ccccc1 Show InChI InChI=1S/C35H32N4O3/c1-35-33(41-3)26(37(2)19-20-11-5-4-6-12-20)17-27(42-35)38-24-15-9-7-13-21(24)29-30-23(18-36-34(30)40)28-22-14-8-10-16-25(22)39(35)32(28)31(29)38/h4-16,26-27,33H,17-19H2,1-3H3,(H,36,40)/t26-,27-,33-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283896
(CHEMBL131020 | N-[3-methoxy-2-methyl-16-oxo-(2R,3S...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)S(C)(=O)=O Show InChI InChI=1S/C29H28N4O5S/c1-29-27(37-3)20(31(2)39(4,35)36)13-21(38-29)32-18-11-7-5-9-15(18)23-24-17(14-30-28(24)34)22-16-10-6-8-12-19(16)33(29)26(22)25(23)32/h5-12,20-21,27H,13-14H2,1-4H3,(H,30,34)/t20-,21-,27-,29+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283906
(2-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)CCC#N Show InChI InChI=1S/C31H29N5O3/c1-31-29(38-3)22(34(2)14-8-13-32)15-23(39-31)35-20-11-6-4-9-17(20)25-26-19(16-33-30(26)37)24-18-10-5-7-12-21(18)36(31)28(24)27(25)35/h4-7,9-12,22-23,29H,8,14-16H2,1-3H3,(H,33,37)/t22-,23-,29-,31+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283883
(CHEMBL444337 | methyl 2-[3-methoxy-2-methyl-16-oxo...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)CC(=O)OC Show InChI InChI=1S/C31H30N4O5/c1-31-29(39-4)21(33(2)15-23(36)38-3)13-22(40-31)34-19-11-7-5-9-16(19)25-26-18(14-32-30(26)37)24-17-10-6-8-12-20(17)35(31)28(24)27(25)34/h5-12,21-22,29H,13-15H2,1-4H3,(H,32,37)/t21-,22-,29-,31+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283887
(4-[2-hydroxyhexyl(methyl)amino]-3-methoxy-2-methyl...)Show SMILES CCCCC(O)CN(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C34H38N4O4/c1-5-6-11-19(39)18-36(3)25-16-26-37-23-14-9-7-12-20(23)28-29-22(17-35-33(29)40)27-21-13-8-10-15-24(21)38(31(27)30(28)37)34(2,42-26)32(25)41-4/h7-10,12-15,19,25-26,32,39H,5-6,11,16-18H2,1-4H3,(H,35,40)/t19?,25-,26-,32-,34+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50283903
(18-hydroxy-5-methoxy-6-methyl-4-methylamino-(2S,4S...)Show SMILES CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4C(=O)N[C@@H](O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25-26,29,33H,12H2,1-3H3,(H,30,34)/t15-,18-,25-,26-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of Src tyrosine kinase |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM31094
(PKC-412 | cid_24202429)Show SMILES [H][C@@]12C[C@@H]([C@H](OC)[C@@](C)(O1)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 |TLB:11:10:9:4.3.2,17:33:9:4.3.2,THB:24:32:9:4.3.2,5:4:9:10.31.33.32,30:31:9:4.3.2| Show InChI InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283889
(CHEMBL130049 | Staurosporine derivative)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)OC Show InChI InChI=1S/C30H28N4O5/c1-30-27(37-3)20(32(2)29(36)38-4)13-21(39-30)33-18-11-7-5-9-15(18)23-24-17(14-31-28(24)35)22-16-10-6-8-12-19(16)34(30)26(22)25(23)33/h5-12,20-21,27H,13-14H2,1-4H3,(H,31,35)/t20-,21-,27-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283893
(1N-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(C)=O Show InChI InChI=1S/C30H28N4O4/c1-15(35)32(3)21-13-22-33-19-11-7-5-9-16(19)24-25-18(14-31-29(25)36)23-17-10-6-8-12-20(17)34(27(23)26(24)33)30(2,38-22)28(21)37-4/h5-12,21-22,28H,13-14H2,1-4H3,(H,31,36)/t21-,22-,28-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283901
(CHEMBL335931 | Staurosporine derivative)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)CNC(=O)OC(C)(C)C Show InChI InChI=1S/C35H37N5O6/c1-34(2,3)46-33(43)37-17-24(41)38(5)23-15-25-39-21-13-9-7-11-18(21)27-28-20(16-36-32(28)42)26-19-12-8-10-14-22(19)40(30(26)29(27)39)35(4,45-25)31(23)44-6/h7-14,23,25,31H,15-17H2,1-6H3,(H,36,42)(H,37,43)/t23-,25-,31-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283882
(3-methoxy-4-[4-methoxyphenyl(methyl)carboxamido]-2...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C36H32N4O5/c1-36-33(44-4)26(38(2)35(42)19-13-15-20(43-3)16-14-19)17-27(45-36)39-24-11-7-5-9-21(24)29-30-23(18-37-34(30)41)28-22-10-6-8-12-25(22)40(36)32(28)31(29)39/h5-16,26-27,33H,17-18H2,1-4H3,(H,37,41)/t26-,27-,33-,36+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283898
(4-[3-chlorophenyl(methyl)carboxamido]-3-methoxy-2-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C35H29ClN4O4/c1-35-32(43-3)25(38(2)34(42)18-9-8-10-19(36)15-18)16-26(44-35)39-23-13-6-4-11-20(23)28-29-22(17-37-33(29)41)27-21-12-5-7-14-24(21)40(35)31(27)30(28)39/h4-15,25-26,32H,16-17H2,1-3H3,(H,37,41)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283897
(4-[2-chlorophenyl(methyl)carboxamido]-3-methoxy-2-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1Cl Show InChI InChI=1S/C35H29ClN4O4/c1-35-32(43-3)25(38(2)34(42)18-10-4-7-13-22(18)36)16-26(44-35)39-23-14-8-5-11-19(23)28-29-21(17-37-33(29)41)27-20-12-6-9-15-24(20)40(35)31(27)30(28)39/h4-15,25-26,32H,16-17H2,1-3H3,(H,37,41)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283904
(3-methoxy-2-methyl-4-methyl(3-nitrophenyl)carboxam...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C35H29N5O6/c1-35-32(45-3)25(37(2)34(42)18-9-8-10-19(15-18)40(43)44)16-26(46-35)38-23-13-6-4-11-20(23)28-29-22(17-36-33(29)41)27-21-12-5-7-14-24(21)39(35)31(27)30(28)38/h4-15,25-26,32H,16-17H2,1-3H3,(H,36,41)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283912
(1N-[3-methoxy-2-methyl-16-oxo-(2R,3S,4S,6S)-29-oxa...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)C(F)(F)F Show InChI InChI=1S/C30H25F3N4O4/c1-29-26(40-3)19(35(2)28(39)30(31,32)33)12-20(41-29)36-17-10-6-4-8-14(17)22-23-16(13-34-27(23)38)21-15-9-5-7-11-18(15)37(29)25(21)24(22)36/h4-11,19-20,26H,12-13H2,1-3H3,(H,34,38)/t19-,20-,26-,29+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283910
(4-[4-chlorophenyl(methyl)carboxamido]-3-methoxy-2-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C35H29ClN4O4/c1-35-32(43-3)25(38(2)34(42)18-12-14-19(36)15-13-18)16-26(44-35)39-23-10-6-4-8-20(23)28-29-22(17-37-33(29)41)27-21-9-5-7-11-24(21)40(35)31(27)30(28)39/h4-15,25-26,32H,16-17H2,1-3H3,(H,37,41)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283878
(CHEMBL336192 | Staurosporine derivative)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccc(cc1)C(=O)OC Show InChI InChI=1S/C37H32N4O6/c1-37-33(45-3)26(39(2)35(43)19-13-15-20(16-14-19)36(44)46-4)17-27(47-37)40-24-11-7-5-9-21(24)29-30-23(18-38-34(30)42)28-22-10-6-8-12-25(22)41(37)32(28)31(29)40/h5-16,26-27,33H,17-18H2,1-4H3,(H,38,42)/t26-,27-,33-,37+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283881
(3-methoxy-2-methyl-4-methyl(3-pyridyl)carboxamido-...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1cccnc1 Show InChI InChI=1S/C34H29N5O4/c1-34-31(42-3)24(37(2)33(41)18-9-8-14-35-16-18)15-25(43-34)38-22-12-6-4-10-19(22)27-28-21(17-36-32(28)40)26-20-11-5-7-13-23(20)39(34)30(26)29(27)38/h4-14,16,24-25,31H,15,17H2,1-3H3,(H,36,40)/t24-,25-,31-,34+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283905
(3-methoxy-2-methyl-4-methyl(2-pyrazinyl)carboxamid...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1cnccn1 Show InChI InChI=1S/C33H28N6O4/c1-33-30(42-3)23(37(2)32(41)20-16-34-12-13-35-20)14-24(43-33)38-21-10-6-4-8-17(21)26-27-19(15-36-31(27)40)25-18-9-5-7-11-22(18)39(33)29(25)28(26)38/h4-13,16,23-24,30H,14-15H2,1-3H3,(H,36,40)/t23-,24-,30-,33+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283879
(3-methoxy-2-methyl-4-methyl[methylamino(thioxo)met...)Show SMILES CNC(=S)N(C)[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C30H29N5O3S/c1-30-27(37-4)20(33(3)29(39)31-2)13-21(38-30)34-18-11-7-5-9-15(18)23-24-17(14-32-28(24)36)22-16-10-6-8-12-19(16)35(30)26(22)25(23)34/h5-12,20-21,27H,13-14H2,1-4H3,(H,31,39)(H,32,36)/t20-,21-,27-,30+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283884
(CHEMBL338449 | Staurosporine derivative)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)OC(C)(C)C Show InChI InChI=1S/C33H34N4O5/c1-32(2,3)42-31(39)35(5)22-15-23-36-20-13-9-7-11-17(20)25-26-19(16-34-30(26)38)24-18-12-8-10-14-21(18)37(28(24)27(25)36)33(4,41-23)29(22)40-6/h7-14,22-23,29H,15-16H2,1-6H3,(H,34,38)/t22-,23-,29-,33+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283880
(4-[3,5-dinitrophenyl(methyl)carboxamido]-3-methoxy...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1cc(cc(c1)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C35H28N6O8/c1-35-32(48-3)25(37(2)34(43)17-12-18(40(44)45)14-19(13-17)41(46)47)15-26(49-35)38-23-10-6-4-8-20(23)28-29-22(16-36-33(29)42)27-21-9-5-7-11-24(21)39(35)31(27)30(28)38/h4-14,25-26,32H,15-16H2,1-3H3,(H,36,42)/t25-,26-,32-,35+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283911
(CHEMBL131456 | methyl 2-[3-methoxy-2-methyl-4-meth...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CN(CC(=O)OC)C(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 Show InChI InChI=1S/C38H34N4O6/c1-38-35(47-4)27(39(2)36(44)21-12-6-5-7-13-21)18-28(48-38)41-25-16-10-8-14-22(25)31-32-24(19-40(37(32)45)20-29(43)46-3)30-23-15-9-11-17-26(23)42(38)34(30)33(31)41/h5-17,27-28,35H,18-20H2,1-4H3/t27-,28-,35-,38+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50283914
(17-benzyl-3-methoxy-2-methyl-4-methyl(phenyl)carbo...)Show SMILES CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4CN(Cc5ccccc5)C(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 Show InChI InChI=1S/C42H36N4O4/c1-42-39(49-3)32(43(2)40(47)26-16-8-5-9-17-26)22-33(50-42)45-30-20-12-10-18-27(30)35-36-29(24-44(41(36)48)23-25-14-6-4-7-15-25)34-28-19-11-13-21-31(28)46(42)38(34)37(35)45/h4-21,32-33,39H,22-24H2,1-3H3/t32-,33-,39-,42+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibitory activity against protein tyrosine kinase of Epidermal growth factor receptor was determined |
Bioorg Med Chem Lett 4: 399-404 (1994)
Article DOI: 10.1016/0960-894X(94)80004-9
BindingDB Entry DOI: 10.7270/Q2R211BD |
More data for this
Ligand-Target Pair | |
Search and Browse
