Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 50000282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C13H18N2O/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) Show SMILES COc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI InChI=1S/C15H20N2O/c1-17-7-3-4-12(17)8-11-10-16-15-6-5-13(18-2)9-14(11)15/h5-6,9-10,12,16H,3-4,7-8H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Pfizer, Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.				J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair				3D Structure (crystal)