Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM25756 ((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right ... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM25756 ((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM25756 ((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM50289372 ((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta-1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50289372 ((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta1-adrenergic blocking effect by measuring the ability to inhibit the positive inotropic effect of isoproterenol on the isolated right ... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM50289372 ((S)-1,1-Difluoro-3-isopropylamino-1-[4-(2-methoxy-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for beta-2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle o... | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50214285 (CHEMBL279012) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was tested for its ability to inhibit (-)-[3H]dihydroalprenolol binding to beta-adrenergic receptor sites in rat cortex | Bioorg Med Chem Lett 7: 1273-1274 (1997) Article DOI: 10.1016/S0960-894X(97)00207-2 BindingDB Entry DOI: 10.7270/Q2SX6D7F | |||||||||||
More data for this Ligand-Target Pair |