Found 38 hits Enz. Inhib. hit(s) with all data for entry = 50029946 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES COC(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C20H24ClNO4/c1-14(22-12-19(23)16-4-3-5-17(21)11-16)10-15-6-8-18(9-7-15)26-13-20(24)25-2/h3-9,11,14,19,22-23H,10,12-13H2,1-2H3/t14-,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289563
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(=O)NO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O4/c1-13(21-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)26-12-19(24)22-25/h2-8,10,13,18,21,23,25H,9,11-12H2,1H3,(H,22,24)/t13-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289567
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES COC(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C20H24ClNO4/c1-14(22-12-19(23)16-4-3-5-17(21)11-16)10-15-6-8-18(9-7-15)26-13-20(24)25-2/h3-9,11,14,19,22-23H,10,12-13H2,1-2H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289564
((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCCO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H24ClNO3/c1-14(11-15-5-7-18(8-6-15)24-10-9-22)21-13-19(23)16-3-2-4-17(20)12-16/h2-8,12,14,19,21-23H,9-11,13H2,1H3/t14-,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289563
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(=O)NO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O4/c1-13(21-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)26-12-19(24)22-25/h2-8,10,13,18,21,23,25H,9,11-12H2,1H3,(H,22,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289567
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002133
((+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydrox...)Show SMILES C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
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CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50073045
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCS(O)(=O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H22ClNO5S/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
| Article
| 806 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002133
((+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydrox...)Show SMILES C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
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CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
| 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002133
((+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydrox...)Show SMILES C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
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| Article
| 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES COC(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C20H24ClNO4/c1-14(22-12-19(23)16-4-3-5-17(21)11-16)10-15-6-8-18(9-7-15)26-13-20(24)25-2/h3-9,11,14,19,22-23H,10,12-13H2,1-2H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289564
((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCCO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H24ClNO3/c1-14(11-15-5-7-18(8-6-15)24-10-9-22)21-13-19(23)16-3-2-4-17(20)12-16/h2-8,12,14,19,21-23H,9-11,13H2,1H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289563
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(=O)NO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O4/c1-13(21-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)26-12-19(24)22-25/h2-8,10,13,18,21,23,25H,9,11-12H2,1H3,(H,22,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289564
((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCCO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H24ClNO3/c1-14(11-15-5-7-18(8-6-15)24-10-9-22)21-13-19(23)16-3-2-4-17(20)12-16/h2-8,12,14,19,21-23H,9-11,13H2,1H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50073045
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCS(O)(=O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H22ClNO5S/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H,22,23,24)/t13-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
| Article
| 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289567
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50073045
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCS(O)(=O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H22ClNO5S/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
| Article
| 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289566
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H22ClNO6/c1-12(22-11-17(23)14-3-2-4-15(21)10-14)9-13-5-7-16(8-6-13)28-18(19(24)25)20(26)27/h2-8,10,12,17-18,22-23H,9,11H2,1H3,(H,24,25)(H,26,27)/t12-,17+/m1/s1 | PDB
Reactome pathway
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UniChem
Similars
| Article
| 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289566
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H22ClNO6/c1-12(22-11-17(23)14-3-2-4-15(21)10-14)9-13-5-7-16(8-6-13)28-18(19(24)25)20(26)27/h2-8,10,12,17-18,22-23H,9,11H2,1H3,(H,24,25)(H,26,27)/t12-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289568
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES CC(C)OP(O)(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C21H29ClNO5P/c1-15(2)28-29(25,26)14-27-20-9-7-17(8-10-20)11-16(3)23-13-21(24)18-5-4-6-19(22)12-18/h4-10,12,15-16,21,23-24H,11,13-14H2,1-3H3,(H,25,26)/t16-,21+/m1/s1 | PDB
Reactome pathway
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UniChem
Similars
| Article
| 1.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289565
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(C)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H25ClNO4P/c1-14(21-12-19(22)16-4-3-5-17(20)11-16)10-15-6-8-18(9-7-15)25-13-26(2,23)24/h3-9,11,14,19,21-22H,10,12-13H2,1-2H3,(H,23,24)/t14-,19+/m1/s1 | PDB
Reactome pathway
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Similars
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| 1.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289569
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(O)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H23ClNO5P/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H2,22,23,24)/t13-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
Similars
| Article
| 3.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289568
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES CC(C)OP(O)(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C21H29ClNO5P/c1-15(2)28-29(25,26)14-27-20-9-7-17(8-10-20)11-16(3)23-13-21(24)18-5-4-6-19(22)12-18/h4-10,12,15-16,21,23-24H,11,13-14H2,1-3H3,(H,25,26)/t16-,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Similars
| Article
| 4.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289569
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(O)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H23ClNO5P/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H2,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
| 5.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289565
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(C)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H25ClNO4P/c1-14(21-12-19(22)16-4-3-5-17(20)11-16)10-15-6-8-18(9-7-15)25-13-26(2,23)24/h3-9,11,14,19,21-22H,10,12-13H2,1-2H3,(H,23,24)/t14-,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 7.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289569
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(O)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H23ClNO5P/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H2,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289568
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES CC(C)OP(O)(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C21H29ClNO5P/c1-15(2)28-29(25,26)14-27-20-9-7-17(8-10-20)11-16(3)23-13-21(24)18-5-4-6-19(22)12-18/h4-10,12,15-16,21,23-24H,11,13-14H2,1-3H3,(H,25,26)/t16-,21+/m1/s1 | PDB
Reactome pathway
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UniChem
Similars
| Article
| 1.39E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289565
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(C)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H25ClNO4P/c1-14(21-12-19(22)16-4-3-5-17(20)11-16)10-15-6-8-18(9-7-15)25-13-26(2,23)24/h3-9,11,14,19,21-22H,10,12-13H2,1-2H3,(H,23,24)/t14-,19+/m1/s1 | PDB
Reactome pathway
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UniChem
Similars
| Article
| 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289566
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OC(C(O)=O)C(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H22ClNO6/c1-12(22-11-17(23)14-3-2-4-15(21)10-14)9-13-5-7-16(8-6-13)28-18(19(24)25)20(26)27/h2-8,10,12,17-18,22-23H,9,11H2,1H3,(H,24,25)(H,26,27)/t12-,17+/m1/s1 | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
| 2.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289564
((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCCO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H24ClNO3/c1-14(11-15-5-7-18(8-6-15)24-10-9-22)21-13-19(23)16-3-2-4-17(20)12-16/h2-8,12,14,19,21-23H,9-11,13H2,1H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002133
((+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydrox...)Show SMILES C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H22ClNO4/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cells |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289563
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(=O)NO)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O4/c1-13(21-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)26-12-19(24)22-25/h2-8,10,13,18,21,23,25H,9,11-12H2,1H3,(H,22,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50002132
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES COC(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C20H24ClNO4/c1-14(22-12-19(23)16-4-3-5-17(21)11-16)10-15-6-8-18(9-7-15)26-13-20(24)25-2/h3-9,11,14,19,22-23H,10,12-13H2,1-2H3/t14-,19+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | n/a | n/a | 420 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50073045
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCS(O)(=O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H22ClNO5S/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289568
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES CC(C)OP(O)(=O)COc1ccc(C[C@@H](C)NC[C@H](O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C21H29ClNO5P/c1-15(2)28-29(25,26)14-27-20-9-7-17(8-10-20)11-16(3)23-13-21(24)18-5-4-6-19(22)12-18/h4-10,12,15-16,21,23-24H,11,13-14H2,1-3H3,(H,25,26)/t16-,21+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289567
(2-(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-eth...)Show SMILES C[C@H](Cc1ccc(OCC(N)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H23ClN2O3/c1-13(22-11-18(23)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(21)24/h2-8,10,13,18,22-23H,9,11-12H2,1H3,(H2,21,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50289569
((4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethyl...)Show SMILES C[C@H](Cc1ccc(OCP(O)(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C18H23ClNO5P/c1-13(20-11-18(21)15-3-2-4-16(19)10-15)9-14-5-7-17(8-6-14)25-12-26(22,23)24/h2-8,10,13,18,20-21H,9,11-12H2,1H3,(H2,22,23,24)/t13-,18+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranes |
Bioorg Med Chem Lett 7: 1583-1588 (1997)
Article DOI: 10.1016/S0960-894X(97)00266-7
BindingDB Entry DOI: 10.7270/Q24749VQ |
More data for this
Ligand-Target Pair | |
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