Found 95 hits Enz. Inhib. hit(s) with all data for entry = 50008737 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403728
(CHEMBL2112312)Show SMILES CC[C@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076687
(5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C14H12F3NO2/c1-7-2-3-18-11-6-12-9(4-8(7)11)10(14(15,16)17)5-13(19)20-12/h4-7,18H,2-3H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076697
(4-Trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-a...)Show InChI InChI=1S/C13H10F3NO2/c14-13(15,16)9-5-12(18)19-11-6-10-7(4-8(9)11)2-1-3-17-10/h4-6,17H,1-3H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076688
(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)Show InChI InChI=1S/C15H14F3NO2/c1-2-9-4-3-8-5-10-11(15(16,17)18)6-14(20)21-13(10)7-12(8)19-9/h5-7,9,19H,2-4H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076693
(5-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa...)Show InChI InChI=1S/C15H14F3NO2/c1-2-8-3-4-19-12-7-13-10(5-9(8)12)11(15(16,17)18)6-14(20)21-13/h5-8,19H,2-4H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076691
(7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C15H14F3NO2/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(20)21-12(9)7-11(8)19-14/h5-7,19H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403729
(CHEMBL2112311)Show SMILES CC[C@@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076684
(4,5-Bis-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8...)Show InChI InChI=1S/C14H9F6NO2/c15-13(16,17)8-1-2-21-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(22)23-11/h3-5,8,21H,1-2H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM18161
((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076692
(5-Propyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C16H16F3NO2/c1-2-3-9-4-5-20-13-8-14-11(6-10(9)13)12(16(17,18)19)7-15(21)22-14/h6-9,20H,2-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076694
(5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...)Show SMILES FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F Show InChI InChI=1S/C15H9F8NO2/c16-13(17,15(21,22)23)8-1-2-24-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(25)26-11/h3-5,8,24H,1-2H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076696
(CHEMBL6721 | trans-5,7-Diethyl-4-trifluoromethyl-5...)Show InChI InChI=1S/C17H18F3NO2/c1-3-9-5-10(4-2)21-14-8-15-12(6-11(9)14)13(17(18,19)20)7-16(22)23-15/h6-10,21H,3-5H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076685
(7-Ethyl-6-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)Show InChI InChI=1S/C16H16F3NO2/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(21)22-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076697
(4-Trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-a...)Show InChI InChI=1S/C13H10F3NO2/c14-13(15,16)9-5-12(18)19-11-6-10-7(4-8(9)11)2-1-3-17-10/h4-6,17H,1-3H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076688
(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)Show InChI InChI=1S/C15H14F3NO2/c1-2-9-4-3-8-5-10-11(15(16,17)18)6-14(20)21-13(10)7-12(8)19-9/h5-7,9,19H,2-4H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM18161
((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |r| Show InChI InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076689
(5-Ethyl-8-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)Show InChI InChI=1S/C16H16F3NO2/c1-3-9-4-5-20(2)13-8-14-11(6-10(9)13)12(16(17,18)19)7-15(21)22-14/h6-9H,3-5H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403730
(CHEMBL2052002)Show SMILES CC[C@H]1CNc2cc3oc(=O)cc(c3cc2[C@@H]1CC)C(F)(F)F |r| Show InChI InChI=1S/C17H18F3NO2/c1-3-9-8-21-14-7-15-12(5-11(14)10(9)4-2)13(17(18,19)20)6-16(22)23-15/h5-7,9-10,21H,3-4,8H2,1-2H3/t9-,10+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro agonistic activity against human androgen receptor (hAR) expressed in CV-1 cells; not active |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076685
(7-Ethyl-6-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)Show InChI InChI=1S/C16H16F3NO2/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(21)22-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076696
(CHEMBL6721 | trans-5,7-Diethyl-4-trifluoromethyl-5...)Show InChI InChI=1S/C17H18F3NO2/c1-3-9-5-10(4-2)21-14-8-15-12(6-11(9)14)13(17(18,19)20)7-16(22)23-15/h6-10,21H,3-5H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076684
(4,5-Bis-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8...)Show InChI InChI=1S/C14H9F6NO2/c15-13(16,17)8-1-2-21-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(22)23-11/h3-5,8,21H,1-2H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076692
(5-Propyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C16H16F3NO2/c1-2-3-9-4-5-20-13-8-14-11(6-10(9)13)12(16(17,18)19)7-15(21)22-14/h6-9,20H,2-5H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076693
(5-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa...)Show InChI InChI=1S/C15H14F3NO2/c1-2-8-3-4-19-12-7-13-10(5-9(8)12)11(15(16,17)18)6-14(20)21-13/h5-8,19H,2-4H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403729
(CHEMBL2112311)Show SMILES CC[C@@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076694
(5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...)Show SMILES FC(F)(F)c1cc(=O)oc2cc3NCCC(c3cc12)C(F)(F)C(F)(F)F Show InChI InChI=1S/C15H9F8NO2/c16-13(17,15(21,22)23)8-1-2-24-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(25)26-11/h3-5,8,24H,1-2H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076687
(5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C14H12F3NO2/c1-7-2-3-18-11-6-12-9(4-8(7)11)10(14(15,16)17)5-13(19)20-12/h4-7,18H,2-3H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cells |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403728
(CHEMBL2112312)Show SMILES CC[C@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076699
(CHEMBL269305 | cis-7-Ethyl-5-methyl-4-trifluoromet...)Show InChI InChI=1S/C16H16F3NO2/c1-3-9-4-8(2)10-5-11-12(16(17,18)19)6-15(21)22-14(11)7-13(10)20-9/h5-9,20H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076691
(7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C15H14F3NO2/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(20)21-12(9)7-11(8)19-14/h5-7,19H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM18525
(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)Show SMILES CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB PubMed
| n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076699
(CHEMBL269305 | cis-7-Ethyl-5-methyl-4-trifluoromet...)Show InChI InChI=1S/C16H16F3NO2/c1-3-9-4-8(2)10-5-11-12(16(17,18)19)6-15(21)22-14(11)7-13(10)20-9/h5-9,20H,3-4H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50403731
(CHEMBL2112216)Show SMILES CC[C@H]1C[C@@H](C)Nc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-4-8(2)20-13-7-14-11(5-10(9)13)12(16(17,18)19)6-15(21)22-14/h5-9,20H,3-4H2,1-2H3/t8-,9+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50403727
(CHEMBL2112310)Show SMILES CC[C@@H]1CNc2cc3oc(=O)cc(c3cc2[C@H]1CC)C(F)(F)F |r| Show InChI InChI=1S/C17H18F3NO2/c1-3-9-8-21-14-7-15-12(5-11(14)10(9)4-2)13(17(18,19)20)6-16(22)23-15/h5-7,9-10,21H,3-4,8H2,1-2H3/t9-,10+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076695
(5,7,7-Trimethyl-4-trifluoromethyl-7,8-dihydro-1-ox...)Show SMILES CC1=CC(C)(C)Nc2cc3oc(=O)cc(c3cc12)C(F)(F)F |t:1| Show InChI InChI=1S/C16H14F3NO2/c1-8-7-15(2,3)20-12-6-13-10(4-9(8)12)11(16(17,18)19)5-14(21)22-13/h4-7,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076692
(5-Propyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C16H16F3NO2/c1-2-3-9-4-5-20-13-8-14-11(6-10(9)13)12(16(17,18)19)7-15(21)22-14/h6-9,20H,2-5H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM18525
(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)Show SMILES CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro binding affinity at human androgen receptor transfected into COS cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50403728
(CHEMBL2112312)Show SMILES CC[C@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50403729
(CHEMBL2112311)Show SMILES CC[C@@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076693
(5-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa...)Show InChI InChI=1S/C15H14F3NO2/c1-2-8-3-4-19-12-7-13-10(5-9(8)12)11(15(16,17)18)6-14(20)21-13/h5-8,19H,2-4H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076684
(4,5-Bis-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8...)Show InChI InChI=1S/C14H9F6NO2/c15-13(16,17)8-1-2-21-10-5-11-7(3-6(8)10)9(14(18,19)20)4-12(22)23-11/h3-5,8,21H,1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50076689
(5-Ethyl-8-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)Show InChI InChI=1S/C16H16F3NO2/c1-3-9-4-5-20(2)13-8-14-11(6-10(9)13)12(16(17,18)19)7-15(21)22-14/h6-9H,3-5H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 276 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells. |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076687
(5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)Show InChI InChI=1S/C14H12F3NO2/c1-7-2-3-18-11-6-12-9(4-8(7)11)10(14(15,16)17)5-13(19)20-12/h4-7,18H,2-3H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50403729
(CHEMBL2112311)Show SMILES CC[C@@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human glucocorticoid receptor (hGR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076685
(7-Ethyl-6-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)Show InChI InChI=1S/C16H16F3NO2/c1-3-12-8(2)4-9-5-10-11(16(17,18)19)6-15(21)22-14(10)7-13(9)20-12/h5-8,12,20H,3-4H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50076691
(7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C15H14F3NO2/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(20)21-12(9)7-11(8)19-14/h5-7,19H,3-4H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human progesterone receptor (hPR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50076691
(7,7-Dimethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C15H14F3NO2/c1-14(2)4-3-8-5-9-10(15(16,17)18)6-13(20)21-12(9)7-11(8)19-14/h5-7,19H,3-4H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human mineralocorticoid receptor (hMR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50403727
(CHEMBL2112310)Show SMILES CC[C@@H]1CNc2cc3oc(=O)cc(c3cc2[C@H]1CC)C(F)(F)F |r| Show InChI InChI=1S/C17H18F3NO2/c1-3-9-8-21-14-7-15-12(5-11(14)10(9)4-2)13(17(18,19)20)6-16(22)23-15/h5-7,9-10,21H,3-4,8H2,1-2H3/t9-,10+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human mineralocorticoid receptor (hMR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50403728
(CHEMBL2112312)Show SMILES CC[C@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human glucocorticoid receptor (hGR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50403729
(CHEMBL2112311)Show SMILES CC[C@@H]1[C@H](C)CNc2cc3oc(=O)cc(c3cc12)C(F)(F)F |r| Show InChI InChI=1S/C16H16F3NO2/c1-3-9-8(2)7-20-13-6-14-11(4-10(9)13)12(16(17,18)19)5-15(21)22-14/h4-6,8-9,20H,3,7H2,1-2H3/t8-,9-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human mineralocorticoid receptor (hMR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50403727
(CHEMBL2112310)Show SMILES CC[C@@H]1CNc2cc3oc(=O)cc(c3cc2[C@H]1CC)C(F)(F)F |r| Show InChI InChI=1S/C17H18F3NO2/c1-3-9-8-21-14-7-15-12(5-11(14)10(9)4-2)13(17(18,19)20)6-16(22)23-15/h5-7,9-10,21H,3-4,8H2,1-2H3/t9-,10+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro antagonistic activity against human glucocorticoid receptor (hGR) |
Bioorg Med Chem Lett 9: 1003-8 (1999)
BindingDB Entry DOI: 10.7270/Q2JS9PM8 |
More data for this Ligand-Target Pair | |