Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3) | Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ | |||||||||||
More data for this Ligand-Target Pair |