Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50035255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108509 (5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108512 (5-(4,8,12-Trimethyl-tridecyl)-3a,4,7,7a-tetrahydro...) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC2C(C1)C(=O)OC2=O |t:16| Show InChI InChI=1S/C24H40O3/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21-22(16-20)24(26)27-23(21)25/h14,17-19,21-22H,5-13,15-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108511 (5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50059863 ((Z)-2-Methyl-3-tetradecyl-but-2-enedioic acid | CH...) Show SMILES CCCCCCCCCCCCCC\C(C(O)=O)=C(/C)C(O)=O Show InChI InChI=1S/C19H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19(22)23)16(2)18(20)21/h3-15H2,1-2H3,(H,20,21)(H,22,23)/b17-16-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108509 (5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108509 (5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108507 (CHEMBL420797 | dodecanoic anhydride) Show SMILES CCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCC Show InChI InChI=1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108510 (((E)-3-Dodec-2-enyl)-dihydro-furan-2,5-dione | CHE...) Show SMILES CCCCCCCCC\C=C\CC1CC(=O)OC1=O Show InChI InChI=1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h10-11,14H,2-9,12-13H2,1H3/b11-10+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	4.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108514 (2-Dodec-2-enyl-succinic acid | CHEMBL441996) Show SMILES CCCCCCCCC\C=C\CC(CC(O)=O)C(O)=O Show InChI InChI=1S/C16H28O4/c1-2-3-4-5-6-7-8-9-10-11-12-14(16(19)20)13-15(17)18/h10-11,14H,2-9,12-13H2,1H3,(H,17,18)(H,19,20)/b11-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108505 (4-[(E)-3,7-Dimethyl-octa-2,6-dien-(E)-ylidene]-cyc...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]=[#6]-1/[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C18H26O4/c1-12(2)5-4-6-13(3)7-8-14-9-10-15(17(19)20)16(11-14)18(21)22/h5,7-8,15-16H,4,6,9-11H2,1-3H3,(H,19,20)(H,21,22)/b13-7+,14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108511 (5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108509 (5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of Farnesyltransferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108507 (CHEMBL420797 | dodecanoic anhydride) Show SMILES CCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCC Show InChI InChI=1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108515 (4-(4-Methyl-pent-3-enyl)-cyclohex-4-ene-1,2-dicarb...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O |t:6| Show InChI InChI=1S/C14H20O4/c1-9(2)4-3-5-10-6-7-11(13(15)16)12(8-10)14(17)18/h4,6,11-12H,3,5,7-8H2,1-2H3,(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108516 (4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...) Show SMILES COC(=O)C1CC=C(CCCC(C)CCCC(C)CCCC(C)C)CC1C(=O)OC |t:6| Show InChI InChI=1S/C26H46O4/c1-19(2)10-7-11-20(3)12-8-13-21(4)14-9-15-22-16-17-23(25(27)29-5)24(18-22)26(28)30-6/h16,19-21,23-24H,7-15,17-18H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108514 (2-Dodec-2-enyl-succinic acid | CHEMBL441996) Show SMILES CCCCCCCCC\C=C\CC(CC(O)=O)C(O)=O Show InChI InChI=1S/C16H28O4/c1-2-3-4-5-6-7-8-9-10-11-12-14(16(19)20)13-15(17)18/h10-11,14H,2-9,12-13H2,1H3,(H,17,18)(H,19,20)/b11-10+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108506 (4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC(C(C1)C(O)=O)C(O)=O |t:16| Show InChI InChI=1S/C24H42O4/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21(23(25)26)22(16-20)24(27)28/h14,17-19,21-22H,5-13,15-16H2,1-4H3,(H,25,26)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108505 (4-[(E)-3,7-Dimethyl-octa-2,6-dien-(E)-ylidene]-cyc...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]=[#6]-1/[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C18H26O4/c1-12(2)5-4-6-13(3)7-8-14-9-10-15(17(19)20)16(11-14)18(21)22/h5,7-8,15-16H,4,6,9-11H2,1-3H3,(H,19,20)(H,21,22)/b13-7+,14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108510 (((E)-3-Dodec-2-enyl)-dihydro-furan-2,5-dione | CHE...) Show SMILES CCCCCCCCC\C=C\CC1CC(=O)OC1=O Show InChI InChI=1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h10-11,14H,2-9,12-13H2,1H3/b11-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108515 (4-(4-Methyl-pent-3-enyl)-cyclohex-4-ene-1,2-dicarb...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O |t:6| Show InChI InChI=1S/C14H20O4/c1-9(2)4-3-5-10-6-7-11(13(15)16)12(8-10)14(17)18/h4,6,11-12H,3,5,7-8H2,1-2H3,(H,15,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108512 (5-(4,8,12-Trimethyl-tridecyl)-3a,4,7,7a-tetrahydro...) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC2C(C1)C(=O)OC2=O |t:16| Show InChI InChI=1S/C24H40O3/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21-22(16-20)24(26)27-23(21)25/h14,17-19,21-22H,5-13,15-16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108508 (3-Methylene-dihydro-furan-2,5-dione | CHEMBL87967) Show SMILES C=C1CC(=O)OC1=O Show InChI InChI=1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108508 (3-Methylene-dihydro-furan-2,5-dione | CHEMBL87967) Show SMILES C=C1CC(=O)OC1=O Show InChI InChI=1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h1-2H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50108506 (4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...) Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC(C(C1)C(O)=O)C(O)=O |t:16| Show InChI InChI=1S/C24H42O4/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21(23(25)26)22(16-20)24(27)28/h14,17-19,21-22H,5-13,15-16H2,1-4H3,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand				Bioorg Med Chem Lett 12: 255-9 (2001) BindingDB Entry DOI: 10.7270/Q2GQ6Z93
					More data for this Ligand-Target Pair