BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50012448
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50118955 (CHEMBL94678 \| Compound K-252a(epi)) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of nerve growth factor receptor, trkA				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of nerve growth factor receptor, trkA				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50118955 (CHEMBL94678 \| Compound K-252a(epi)) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-receptor 2 (KDR)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Myosin light chain kinase 1 (MLCK1)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50118955 (CHEMBL94678 \| Compound K-252a(epi)) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Myosin light chain kinase 1 (MLCK1)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-receptor 2 (KDR)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM50118955 (CHEMBL94678 \| Compound K-252a(epi)) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of protein kinase C (PKC)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Homo sapiens (Human))	BDBM6760 ((+)-K-252a \| CHEMBL281948 \| K-252a \| methyl (15S,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of protein kinase C (PKC)				Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair