Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for entry = 50005625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038991 (Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...) Show SMILES Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C16H12ClN3O2/c17-11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038975 (Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...) Show SMILES CSc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2S/c1-23-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038992 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES N#Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H12N4O2/c18-7-11-1-3-14-13(5-11)17(21-9-20-14)19-8-12-2-4-15-16(6-12)23-10-22-15/h1-6,9H,8,10H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038973 (Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...) Show SMILES Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2/c1-11-2-4-14-13(6-11)17(20-9-19-14)18-8-12-3-5-15-16(7-12)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038982 (Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...) Show SMILES COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c1-21-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)23-10-22-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038979 (Benzo[1,3]dioxol-5-ylmethyl-(7-methoxy-6-methylsul...) Show SMILES COc1cc2ncnc(NCc3ccc4OCOc4c3)c2cc1SC Show InChI InChI=1S/C18H17N3O3S/c1-22-16-7-13-12(6-17(16)25-2)18(21-9-20-13)19-8-11-3-4-14-15(5-11)24-10-23-14/h3-7,9H,8,10H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038978 (Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...) Show SMILES COc1cc2c(NCc3ccc4OCOc4c3)ncnc2c(OC)c1OC Show InChI InChI=1S/C19H19N3O5/c1-23-15-7-12-16(18(25-3)17(15)24-2)21-9-22-19(12)20-8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3,(H,20,21,22)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038988 (Benzo[1,3]dioxol-5-ylmethyl-(6-methanesulfinyl-qui...) Show SMILES CS(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3S/c1-24(21)12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)23-10-22-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038995 (Benzo[1,3]dioxol-5-ylmethyl-(6-ethoxy-quinazolin-4...) Show SMILES CCOc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C18H17N3O3/c1-2-22-13-4-5-15-14(8-13)18(21-10-20-15)19-9-12-3-6-16-17(7-12)24-11-23-16/h3-8,10H,2,9,11H2,1H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038986 (3-Benzo[1,3]dioxol-5-ylmethyl-6,7,8-trimethoxy-3H-...) Show SMILES COc1cc2c(ncn(Cc3ccc4OCOc4c3)c2=O)c(OC)c1OC Show InChI InChI=1S/C19H18N2O6/c1-23-15-7-12-16(18(25-3)17(15)24-2)20-9-21(19(12)22)8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038998 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES CCOC(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C19H17N3O4/c1-2-24-19(23)13-4-5-15-14(8-13)18(22-10-21-15)20-9-12-3-6-16-17(7-12)26-11-25-16/h3-8,10H,2,9,11H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50039001 (Benzo[1,3]dioxol-5-ylmethyl-(5,6-dimethoxy-quinazo...) Show SMILES COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1OC Show InChI InChI=1S/C18H17N3O4/c1-22-14-6-4-12-16(17(14)23-2)18(21-9-20-12)19-8-11-3-5-13-15(7-11)25-10-24-13/h3-7,9H,8,10H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM15296 (6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccncc1)C#N Show InChI InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038976 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES NC(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H14N4O3/c18-16(22)11-2-3-13-12(6-11)17(21-8-20-13)19-7-10-1-4-14-15(5-10)24-9-23-14/h1-6,8H,7,9H2,(H2,18,22)(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038989 (Benzo[1,3]dioxol-5-ylmethyl-(6,8-dimethoxy-quinazo...) Show SMILES COc1cc(OC)c2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C18H17N3O4/c1-22-12-6-13-17(16(7-12)23-2)20-9-21-18(13)19-8-11-3-4-14-15(5-11)25-10-24-14/h3-7,9H,8,10H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038999 (Benzo[1,3]dioxol-5-ylmethyl-(6-methanesulfonyl-qui...) Show SMILES CS(=O)(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O4S/c1-25(21,22)12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)24-10-23-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038977 (Benzo[1,3]dioxol-5-ylmethyl-(6,7-dimethoxy-quinazo...) Show SMILES COc1cc2ncnc(NCc3ccc4OCOc4c3)c2cc1OC Show InChI InChI=1S/C18H17N3O4/c1-22-15-6-12-13(7-16(15)23-2)20-9-21-18(12)19-8-11-3-4-14-17(5-11)25-10-24-14/h3-7,9H,8,10H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038974 (CHEMBL68337 | {4-[(Benzo[1,3]dioxol-5-ylmethyl)-am...) Show SMILES OCc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c21-8-12-1-3-14-13(5-12)17(20-9-19-14)18-7-11-2-4-15-16(6-11)23-10-22-15/h1-6,9,21H,7-8,10H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038996 (4-(Benzo[1,3]dioxol-5-ylmethoxy)-6,7,8-trimethoxy-...) Show SMILES COc1cc2c(OCc3ccc4OCOc4c3)ncnc2c(OC)c1OC Show InChI InChI=1S/C19H18N2O6/c1-22-15-7-12-16(18(24-3)17(15)23-2)20-9-21-19(12)25-8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038981 (Benzo[1,3]dioxol-5-ylmethyl-(7-chloro-quinazolin-4...) Show SMILES Clc1ccc2c(NCc3ccc4OCOc4c3)ncnc2c1 Show InChI InChI=1S/C16H12ClN3O2/c17-11-2-3-12-13(6-11)19-8-20-16(12)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038987 (4-(Benzo[1,3]dioxol-5-ylmethoxy)-6-methylsulfanyl-...) Show SMILES CSc1ccc2ncnc(OCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H14N2O3S/c1-23-12-3-4-14-13(7-12)17(19-9-18-14)20-8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038980 (Benzo[1,3]dioxol-5-ylmethyl-[1,3]dioxolo[4,5-g]qui...) Show SMILES C(Nc1ncnc2cc3OCOc3cc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H13N3O4/c1-2-13-14(22-8-21-13)3-10(1)6-18-17-11-4-15-16(24-9-23-15)5-12(11)19-7-20-17/h1-5,7H,6,8-9H2,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038994 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES CN(C)C(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C19H18N4O3/c1-23(2)19(24)13-4-5-15-14(8-13)18(22-10-21-15)20-9-12-3-6-16-17(7-12)26-11-25-16/h3-8,10H,9,11H2,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038985 (3-Benzo[1,3]dioxol-5-ylmethyl-6-methylsulfanyl-3H-...) Show SMILES CSc1ccc2ncn(Cc3ccc4OCOc4c3)c(=O)c2c1 Show InChI InChI=1S/C17H14N2O3S/c1-23-12-3-4-14-13(7-12)17(20)19(9-18-14)8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50039000 (CHEMBL304277 | {4-[(Benzo[1,3]dioxol-5-ylmethyl)-a...) Show SMILES O=C(N1CCOCC1)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C21H20N4O4/c26-21(25-5-7-27-8-6-25)15-2-3-17-16(10-15)20(24-12-23-17)22-11-14-1-4-18-19(9-14)29-13-28-18/h1-4,9-10,12H,5-8,11,13H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038993 (3-Benzo[1,3]dioxol-5-ylmethyl-7-methoxy-6-methylsu...) Show SMILES COc1cc2ncn(Cc3ccc4OCOc4c3)c(=O)c2cc1SC Show InChI InChI=1S/C18H16N2O4S/c1-22-16-7-13-12(6-17(16)25-2)18(21)20(9-19-13)8-11-3-4-14-15(5-11)24-10-23-14/h3-7,9H,8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038983 (Benzo[1,3]dioxol-5-ylmethyl-quinazolin-4-yl-amine ...) Show SMILES C(Nc1ncnc2ccccc12)c1ccc2OCOc2c1 Show InChI InChI=1S/C16H13N3O2/c1-2-4-13-12(3-1)16(19-9-18-13)17-8-11-5-6-14-15(7-11)21-10-20-14/h1-7,9H,8,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038990 (Benzo[1,3]dioxol-5-ylmethyl-(8-methoxy-quinazolin-...) Show SMILES COc1cccc2c(NCc3ccc4OCOc4c3)ncnc12 Show InChI InChI=1S/C17H15N3O3/c1-21-14-4-2-3-12-16(14)19-9-20-17(12)18-8-11-5-6-13-15(7-11)23-10-22-13/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038984 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES OC(=O)c1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H13N3O4/c21-17(22)11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)24-9-23-14/h1-6,8H,7,9H2,(H,21,22)(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038978 (Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...) Show SMILES COc1cc2c(NCc3ccc4OCOc4c3)ncnc2c(OC)c1OC Show InChI InChI=1S/C19H19N3O5/c1-23-15-7-12-16(18(25-3)17(15)24-2)21-9-22-19(12)20-8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038997 (3-Benzo[1,3]dioxol-5-ylmethyl-7-chloro-3H-quinazol...) Show SMILES Clc1ccc2c(c1)ncn(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C16H11ClN2O3/c17-11-2-3-12-13(6-11)18-8-19(16(12)20)7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038978 (Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...) Show SMILES COc1cc2c(NCc3ccc4OCOc4c3)ncnc2c(OC)c1OC Show InChI InChI=1S/C19H19N3O5/c1-23-15-7-12-16(18(25-3)17(15)24-2)21-9-22-19(12)20-8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3,(H,20,21,22)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038991 (Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...) Show SMILES Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C16H12ClN3O2/c17-11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038973 (Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...) Show SMILES Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2/c1-11-2-4-14-13(6-11)17(20-9-19-14)18-8-12-3-5-15-16(7-12)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038975 (Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...) Show SMILES CSc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2S/c1-23-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038991 (Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...) Show SMILES Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C16H12ClN3O2/c17-11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038991 (Benzo[1,3]dioxol-5-ylmethyl-(6-chloro-quinazolin-4...) Show SMILES Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C16H12ClN3O2/c17-11-2-3-13-12(6-11)16(20-8-19-13)18-7-10-1-4-14-15(5-10)22-9-21-14/h1-6,8H,7,9H2,(H,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038992 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES N#Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H12N4O2/c18-7-11-1-3-14-13(5-11)17(21-9-20-14)19-8-12-2-4-15-16(6-12)23-10-22-15/h1-6,9H,8,10H2,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038973 (Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...) Show SMILES Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2/c1-11-2-4-14-13(6-11)17(20-9-19-14)18-8-12-3-5-15-16(7-12)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038982 (Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...) Show SMILES COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c1-21-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)23-10-22-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038975 (Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...) Show SMILES CSc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2S/c1-23-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038992 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES N#Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H12N4O2/c18-7-11-1-3-14-13(5-11)17(21-9-20-14)19-8-12-2-4-15-16(6-12)23-10-22-15/h1-6,9H,8,10H2,(H,19,20,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
Phosphodiesterase (Sus scrofa)	BDBM50038992 (4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-quinazolin...) Show SMILES N#Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H12N4O2/c18-7-11-1-3-14-13(5-11)17(21-9-20-14)19-8-12-2-4-15-16(6-12)23-10-22-15/h1-6,9H,8,10H2,(H,19,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP-inhibited PDE 3 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038975 (Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quin...) Show SMILES CSc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2S/c1-23-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cGMP stimulated-PDE 2 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038978 (Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quin...) Show SMILES COc1cc2c(NCc3ccc4OCOc4c3)ncnc2c(OC)c1OC Show InChI InChI=1S/C19H19N3O5/c1-23-15-7-12-16(18(25-3)17(15)24-2)21-9-22-19(12)20-8-11-4-5-13-14(6-11)27-10-26-13/h4-7,9H,8,10H2,1-3H3,(H,20,21,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038973 (Benzo[1,3]dioxol-5-ylmethyl-(6-methyl-quinazolin-4...) Show SMILES Cc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O2/c1-11-2-4-14-13(6-11)17(20-9-19-14)18-8-12-3-5-15-16(7-12)22-10-21-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038982 (Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...) Show SMILES COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c1-21-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)23-10-22-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Sus scrofa)	BDBM50038982 (Benzo[1,3]dioxol-5-ylmethyl-(6-methoxy-quinazolin-...) Show SMILES COc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 Show InChI InChI=1S/C17H15N3O3/c1-21-12-3-4-14-13(7-12)17(20-9-19-14)18-8-11-2-5-15-16(6-11)23-10-22-15/h2-7,9H,8,10H2,1H3,(H,18,19,20)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibition of cAMP specific-PDE 4 from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair