BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50005309
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50035476 (CHEMBL413530 \| N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.000320	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity kappa opioid receptor in guinea pig brain membranes; using 1 nM [3H]-U69,593 as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50035471 (2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity kappa opioid receptor in guinea pig brain membranes, using 1 nM [3H]-U69,593 as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50035476 (CHEMBL413530 \| N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptor in guinea pig brain membranes; using 2 nM [3H]-DAMGO as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50035476 (CHEMBL413530 \| N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor in guinea pig brain membranes; using 2 nM [3H]-DPDPE as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50035471 (2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor in guinea pig brain membranes, using 2 nM [3H]-DPDPE as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50035471 (2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptor in guinea pig brain membranes, using 2 nM [3H]-DAMGO as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50035471 (2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane using [3H]-U-69,593 as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50035476 (CHEMBL413530 \| N-[(S)-1-(3-Amino-phenyl)-2-pyrroli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane; using [3H]-U-69,593 as radioligand				J Med Chem 37: 4490-8 (1995) BindingDB Entry DOI: 10.7270/Q2MW2G5Z
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair