Found 13 hits Enz. Inhib. hit(s) with all data for entry = 50003142 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50025846
(2-[(Imidazole-1-carbonyl)-amino]-pentanoic acid me...)Show InChI InChI=1S/C10H15N3O3/c1-3-4-8(9(14)16-2)12-10(15)13-6-5-11-7-13/h5-8H,3-4H2,1-2H3,(H,12,15)/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of human leukocyte elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225469
(CHEMBL302653)Show InChI InChI=1S/C10H17N3O/c1-3-5-6-12-10(14)13-8-7-11-9(13)4-2/h7-8H,3-6H2,1-2H3,(H,12,14) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50025846
(2-[(Imidazole-1-carbonyl)-amino]-pentanoic acid me...)Show InChI InChI=1S/C10H15N3O3/c1-3-4-8(9(14)16-2)12-10(15)13-6-5-11-7-13/h5-8H,3-4H2,1-2H3,(H,12,15)/t8-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50025852
(2-[(Imidazole-1-carbonyl)-amino]-hexanoic acid met...)Show InChI InChI=1S/C11H17N3O3/c1-3-4-5-9(10(15)17-2)13-11(16)14-7-6-12-8-14/h6-9H,3-5H2,1-2H3,(H,13,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of human leukocyte elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50025849
(2-[(Imidazole-1-carbonyl)-amino]-3-methyl-butyric ...)Show InChI InChI=1S/C10H15N3O3/c1-7(2)8(9(14)16-3)12-10(15)13-5-4-11-6-13/h4-8H,1-3H3,(H,12,15)/t8-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.11E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225473
(CHEMBL65258)Show InChI InChI=1S/C11H17N3O3/c1-8(2)6-9(10(15)17-3)13-11(16)14-5-4-12-7-14/h4-5,7-9H,6H2,1-3H3,(H,13,16)/t9-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.17E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225471
(CHEMBL63295)Show InChI InChI=1S/C11H17N3O3/c1-4-8(2)9(10(15)17-3)13-11(16)14-6-5-12-7-14/h5-9H,4H2,1-3H3,(H,13,16)/t8?,9-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.22E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225472
(CHEMBL63484 | Imidazole-1-Carboxylic Acid Butylami...)Show InChI InChI=1S/C8H13N3O/c1-2-3-4-10-8(12)11-6-5-9-7-11/h5-7H,2-4H2,1H3,(H,10,12) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50025849
(2-[(Imidazole-1-carbonyl)-amino]-3-methyl-butyric ...)Show InChI InChI=1S/C10H15N3O3/c1-7(2)8(9(14)16-3)12-10(15)13-5-4-11-6-13/h4-8H,1-3H3,(H,12,15)/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.80E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of human leukocyte elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50025852
(2-[(Imidazole-1-carbonyl)-amino]-hexanoic acid met...)Show InChI InChI=1S/C11H17N3O3/c1-3-4-5-9(10(15)17-2)13-11(16)14-7-6-12-8-14/h6-9H,3-5H2,1-2H3,(H,13,16) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.94E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225470
(CHEMBL294543)Show InChI InChI=1S/C9H15N3O/c1-3-4-5-11-9(13)12-7-6-10-8(12)2/h6-7H,3-5H2,1-2H3,(H,11,13) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225467
(CHEMBL293476)Show InChI InChI=1S/C15H27N3O/c1-3-5-7-8-9-10-14-16-12-13-18(14)15(19)17-11-6-4-2/h12-13H,3-11H2,1-2H3,(H,17,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |
Chymotrypsin-like elastase family member 1/2A
(Sus scrofa (Pig)) | BDBM50225468
(CHEMBL63581)Show InChI InChI=1S/C9H15N3O/c1-3-4-5-10-9(13)12-6-8(2)11-7-12/h6-7H,3-5H2,1-2H3,(H,10,13) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.23E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Ki value was evaluated for the inhibition of porcine pancreatic elastase |
J Med Chem 28: 204-9 (1985)
BindingDB Entry DOI: 10.7270/Q29S1Q1V |
More data for this Ligand-Target Pair | |