Compile Data Set for Download or QSAR

Found 27 hits Enz. Inhib. hit(s) with all data for entry = 50005818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041356 (1-Ethyl-3-[2-methoxy-4-(toluene-2-sulfonylaminocar...) Show SMILES CCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(C)CC(F)(F)F Show InChI InChI=1S/C32H34F3N3O5S/c1-5-38-19-25(26-15-23(12-13-27(26)38)30(39)36-18-20(2)17-32(33,34)35)14-22-10-11-24(16-28(22)43-4)31(40)37-44(41,42)29-9-7-6-8-21(29)3/h6-13,15-16,19-20H,5,14,17-18H2,1-4H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041349 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC[C@H](C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041357 (1-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cn1cc(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(15-31(32,33)34)16-35-29(38)22-11-12-25-21(3)17-37(26(25)13-22)18-24-10-9-23(14-27(24)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-14,17,19H,15-16,18H2,1-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041344 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041336 (3-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C30H29ClF3N3O5S/c1-18(15-30(32,33)34)16-35-28(38)20-10-11-25-23(13-20)22(17-37(25)2)12-19-8-9-21(14-26(19)42-3)29(39)36-43(40,41)27-7-5-4-6-24(27)31/h4-11,13-14,17-18H,12,15-16H2,1-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041350 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCCC(C(F)(F)F)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H29F6N3O5S/c1-18-6-4-5-7-26(18)46(43,44)39-29(42)21-9-8-19(25(16-21)45-3)14-22-17-40(2)24-11-10-20(15-23(22)24)28(41)38-13-12-27(30(32,33)34)31(35,36)37/h4-11,15-17,27H,12-14H2,1-3H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041352 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1CC(F)(F)C(F)(F)C1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H31F4N3O5S/c1-19-6-4-5-7-28(19)45(42,43)38-30(41)23-9-8-21(27(14-23)44-3)12-24-18-39(2)26-11-10-22(13-25(24)26)29(40)37-17-20-15-31(33,34)32(35,36)16-20/h4-11,13-14,18,20H,12,15-17H2,1-3H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041339 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC[C@@H](C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041353 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(C)CC(F)(F)F Show InChI InChI=1S/C33H36F3N3O5S/c1-5-14-39-20-26(27-16-24(12-13-28(27)39)31(40)37-19-21(2)18-33(34,35)36)15-23-10-11-25(17-29(23)44-4)32(41)38-45(42,43)30-9-7-6-8-22(30)3/h6-13,16-17,20-21H,5,14-15,18-19H2,1-4H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041348 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC\C(C)=C/C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H30F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-16,18H,13,17H2,1-4H3,(H,35,38)(H,36,39)/b19-16-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041360 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H34F3N3O5S/c1-20-8-6-7-9-28(20)44(41,42)37-30(40)23-11-10-21(27(16-23)43-5)14-24-17-38(4)26-13-12-22(15-25(24)26)29(39)36-19-31(2,3)18-32(33,34)35/h6-13,15-17H,14,18-19H2,1-5H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041337 (3-[4-(2-Bromo-benzenesulfonylaminocarbonyl)-2-meth...) Show SMILES CCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3Br)c2c1)CC(F)(F)F Show InChI InChI=1S/C31H31BrF3N3O5S/c1-4-19(16-31(33,34)35)17-36-29(39)21-11-12-26-24(14-21)23(18-38(26)2)13-20-9-10-22(15-27(20)43-3)30(40)37-44(41,42)28-8-6-5-7-25(28)32/h5-12,14-15,18-19H,4,13,16-17H2,1-3H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50000817 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1CCCC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H35N3O5S/c1-21-8-4-7-11-30(21)41(38,39)34-32(37)25-13-12-23(29(18-25)40-3)16-26-20-35(2)28-15-14-24(17-27(26)28)31(36)33-19-22-9-5-6-10-22/h4,7-8,11-15,17-18,20,22H,5-6,9-10,16,19H2,1-3H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041345 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(=C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H30F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18H,1,13,16-17H2,2-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041340 (1-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cn1ccc2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C29H27ClF3N3O5S/c1-18(15-29(31,32)33)16-34-27(37)20-8-7-19-11-12-36(24(19)13-20)17-22-10-9-21(14-25(22)41-2)28(38)35-42(39,40)26-6-4-3-5-23(26)30/h3-14,18H,15-17H2,1-2H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041347 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1(CC(F)(F)F)CC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H32F3N3O5S/c1-20-6-4-5-7-28(20)44(41,42)37-30(40)23-9-8-21(27(16-23)43-3)14-24-17-38(2)26-11-10-22(15-25(24)26)29(39)36-19-31(12-13-31)18-32(33,34)35/h4-11,15-17H,12-14,18-19H2,1-3H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041341 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(CC)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C32H37N3O5S/c1-6-22(7-2)19-33-31(36)24-14-15-28-27(17-24)26(20-35(28)4)16-23-12-13-25(18-29(23)40-5)32(37)34-41(38,39)30-11-9-8-10-21(30)3/h8-15,17-18,20,22H,6-7,16,19H2,1-5H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041355 (1-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cn1cc(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C30H29ClF3N3O5S/c1-18(14-30(32,33)34)15-35-28(38)20-10-11-23-19(2)16-37(25(23)12-20)17-22-9-8-21(13-26(22)42-3)29(39)36-43(40,41)27-7-5-4-6-24(27)31/h4-13,16,18H,14-15,17H2,1-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041338 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCCCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(F)(F)F Show InChI InChI=1S/C33H36F3N3O5S/c1-5-6-10-26(33(34,35)36)19-37-31(40)23-14-15-28-27(17-23)25(20-39(28)3)16-22-12-13-24(18-29(22)44-4)32(41)38-45(42,43)30-11-8-7-9-21(30)2/h7-9,11-15,17-18,20,26H,5-6,10,16,19H2,1-4H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041342 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(C)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C31H35N3O5S/c1-6-20(2)18-32-30(35)23-13-14-27-26(16-23)25(19-34(27)4)15-22-11-12-24(17-28(22)39-5)31(36)33-40(37,38)29-10-8-7-9-21(29)3/h7-14,16-17,19-20H,6,15,18H2,1-5H3,(H,32,35)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041351 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)CC(F)(F)F Show InChI InChI=1S/C32H34F3N3O5S/c1-5-21(17-32(33,34)35)18-36-30(39)23-12-13-27-26(15-23)25(19-38(27)3)14-22-10-11-24(16-28(22)43-4)31(40)37-44(41,42)29-9-7-6-8-20(29)2/h6-13,15-16,19,21H,5,14,17-18H2,1-4H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041343 (1-Ethyl-3-[2-methoxy-4-(toluene-2-sulfonylaminocar...) Show SMILES CCC(CNC(=O)c1ccc2n(CC)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(F)(F)F Show InChI InChI=1S/C32H34F3N3O5S/c1-5-25(32(33,34)35)18-36-30(39)22-13-14-27-26(16-22)24(19-38(27)6-2)15-21-11-12-23(17-28(21)43-4)31(40)37-44(41,42)29-10-8-7-9-20(29)3/h7-14,16-17,19,25H,5-6,15,18H2,1-4H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041346 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCCC(C)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19-7-5-6-8-28(19)43(40,41)36-30(39)23-10-9-21(27(17-23)42-4)15-24-18-37(3)26-12-11-22(16-25(24)26)29(38)35-14-13-20(2)31(32,33)34/h5-12,16-18,20H,13-15H2,1-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041354 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCCCC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C30H30F3N3O5S/c1-19-7-4-5-8-27(19)42(39,40)35-29(38)22-10-9-20(26(17-22)41-3)15-23-18-36(2)25-12-11-21(16-24(23)25)28(37)34-14-6-13-30(31,32)33/h4-5,7-12,16-18H,6,13-15H2,1-3H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041358 (1-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cn1ccc2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C30H30F3N3O5S/c1-19(16-30(31,32)33)17-34-28(37)22-9-8-21-12-13-36(25(21)14-22)18-24-11-10-23(15-26(24)41-3)29(38)35-42(39,40)27-7-5-4-6-20(27)2/h4-15,19H,16-18H2,1-3H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041359 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C30H30F3N3O5S/c1-18-7-5-6-8-27(18)42(39,40)35-29(38)22-10-9-20(26(15-22)41-4)13-23-17-36(3)25-12-11-21(14-24(23)25)28(37)34-16-19(2)30(31,32)33/h5-12,14-15,17,19H,13,16H2,1-4H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair