BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50004909
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029954 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029955 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029951 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029953 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029957 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029956 (4-(3-Cyclopentyloxy-4-methoxy-benzyl)-imidazolidin...) Show SMILES COc1ccc(CC2CNC(=O)N2)cc1OC1CCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029952 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50010981 ((Ro 20-1724)4-(3-Butoxy-4-methoxy-benzyl)-imidazol...) Show SMILES CCCCOc1cc(CC2CNC(=O)N2)ccc1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair