BindingDB PrimarySearch

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50007757
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]-Naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 using [3H]ethylketocyclazocine as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against kOpioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 using [3H]-Ethylketocyclazocine as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50045772 (3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol ...) Show SMILES C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]-Naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	272	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	816	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50045772 (3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol ...) Show SMILES C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	833	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 using [3H]-Ethylketocyclazocine as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair