Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037121 (2-[(1R,3S,4S)-1-BENZYL-4-[N-(BENZYLOXYCARBONYL)-L-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037124 ((R)-2-{(R)-2-[(S)-4-((S)-2-Benzyloxycarbonylamino-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037122 (CHEMBL108016 | [(1S,2S,4R)-1-Benzyl-2-hydroxy-4-(5...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037126 (CHEMBL80098 | [(1S,2S,4R)-1-Benzyl-2-hydroxy-5-phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037125 (CHEMBL107849 | {(S)-1-Benzyl-4-[(S)-1-(carbamoylme...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037128 (CHEMBL419921 | [(1S,2S,4R)-1-Benzyl-4-(5-butyryl-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037123 (CHEMBL108226 | {(1S,2S,4R)-1-Benzyl-4-[5-(2,2-dime...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037127 (CHEMBL104285 | [(1S,2S,4R)-4-(5-Acetyl-1H-imidazol...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037120 (CHEMBL104523 | {(1S,2S,4R)-1-Benzyl-2-hydroxy-4-[5...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037129 (CHEMBL106776 | [(1S,2S,4R)-1-Benzyl-4-(5-formyl-1H...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50037119 (CHEMBL448480 | {(1S,2S,4R)-1-Benzyl-2-hydroxy-4-[5...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant HIV-1 protease | J Med Chem 37: 3100-7 (1994) BindingDB Entry DOI: 10.7270/Q2T72GG9 | |||||||||||
More data for this Ligand-Target Pair |