Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50007164 ((S)-1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037595 (1-((S)-2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037578 (6-(2-{(S)-2-[(Isopropyl-methyl-amino)-methyl]-pipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.07 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037586 (2-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037582 (7-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037592 (6-(2-{(S)-2-[(Methyl-prop-2-ynyl-amino)-methyl]-pi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037594 (2-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 6.54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037577 (6-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037590 (5-[2-Oxo-2-((S)-2-pyrrolidin-1-ylmethyl-piperidin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037591 (6-(2-{(S)-2-[(Ethyl-methyl-amino)-methyl]-piperidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037589 (6-(2-{(S)-2-[(Allyl-methyl-amino)-methyl]-piperidi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037583 (6-(2-{(S)-2-[(Cyclopentyl-methyl-amino)-methyl]-pi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037579 (6-(2-{(S)-2-[(Methyl-propyl-amino)-methyl]-piperid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 22.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037593 (6-(2-{(S)-2-[(Cyclopropylmethyl-methyl-amino)-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037584 (6-(2-{(S)-2-[(Cyclobutyl-methyl-amino)-methyl]-pip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 34.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037581 (6-[2-((S)-2-Dimethylaminomethyl-piperidin-1-yl)-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037580 (6-(2-{(S)-2-[(Cyclopropyl-methyl-amino)-methyl]-pi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 52.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037588 (6-[2-((S)-2-Diethylaminomethyl-piperidin-1-yl)-2-o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 80.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50037581 (6-[2-((S)-2-Dimethylaminomethyl-piperidin-1-yl)-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at delta receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50037585 (6-(2-{(S)-2-[(tert-Butyl-methyl-amino)-methyl]-pip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 301 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50037581 (6-[2-((S)-2-Dimethylaminomethyl-piperidin-1-yl)-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at sigma receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (MOUSE) | BDBM50037581 (6-[2-((S)-2-Dimethylaminomethyl-piperidin-1-yl)-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at mu receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair |