Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with all data for entry = 50005499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards human Dopamine receptor D4.2 using [3H]spiperone as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	>221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	467	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligand				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50048299 (4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...) Show SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037669 (1-[(R)-3-(4-Fluoro-phenyl)-cyclohex-3-enylmethyl]-...) Show SMILES Fc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 |c:17,t:8| Show InChI InChI=1S/C24H26FN/c25-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-26-15-13-22(14-16-26)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037671 (1-[(R)-3-(4-Methoxy-phenyl)-cyclohex-3-enylmethyl]...) Show SMILES COc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 |c:18,t:9| Show InChI InChI=1S/C25H29NO/c1-27-25-12-10-22(11-13-25)24-9-5-6-20(18-24)19-26-16-14-23(15-17-26)21-7-3-2-4-8-21/h2-4,7-14,20H,5-6,15-19H2,1H3/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037670 (4-Phenyl-1-(3-phenyl-cyclohex-3-enylmethyl)-1,2,3,...) Show SMILES C(C1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50453436 (CHEMBL2111778) Show SMILES C([C@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |r,c:4,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037674 (1-(3-Phenyl-cyclohex-3-enylmethyl)-4-pyridin-2-yl-...) Show SMILES C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ccccn1 |c:4| Show InChI InChI=1S/C22H27N3/c1-2-8-20(9-3-1)21-10-6-7-19(17-21)18-24-13-15-25(16-14-24)22-11-4-5-12-23-22/h1-5,8-12,19H,6-7,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037668 (1-(3-Phenyl-cyclohex-3-enylmethyl)-4-thiophen-2-yl...) Show SMILES C(C1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1cccs1 |c:4,18| Show InChI InChI=1S/C22H25NS/c1-2-7-19(8-3-1)21-9-4-6-18(16-21)17-23-13-11-20(12-14-23)22-10-5-15-24-22/h1-3,5,7-11,15,18H,4,6,12-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037672 (4-Phenyl-1-((R)-3-p-tolyl-cyclohex-3-enylmethyl)-1...) Show SMILES Cc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 |c:17,t:8| Show InChI InChI=1S/C25H29N/c1-20-10-12-23(13-11-20)25-9-5-6-21(18-25)19-26-16-14-24(15-17-26)22-7-3-2-4-8-22/h2-4,7-14,21H,5-6,15-19H2,1H3/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037667 (2-[4-(3-Phenyl-cyclohex-3-enylmethyl)-piperazin-1-...) Show SMILES C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ncccn1 |c:4| Show InChI InChI=1S/C21H26N4/c1-2-7-19(8-3-1)20-9-4-6-18(16-20)17-24-12-14-25(15-13-24)21-22-10-5-11-23-21/h1-3,5,7-11,18H,4,6,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	354	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037673 (4-Phenyl-1-(3-phenyl-cyclohex-2-enylmethyl)-1,2,3,...) Show SMILES C(C1CCCC(=C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:5,18| Show InChI InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-12,14,18,20H,7-8,13,15-17,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037680 (1-Phenyl-4-(3-phenyl-cyclohex-3-enylmethyl)-pipera...) Show SMILES C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ccccc1 |c:4| Show InChI InChI=1S/C23H28N2/c1-3-9-21(10-4-1)22-11-7-8-20(18-22)19-24-14-16-25(17-15-24)23-12-5-2-6-13-23/h1-6,9-13,20H,7-8,14-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037679 (4-Phenyl-1-[2-(3-phenyl-cyclohex-3-enyl)-ethyl]-1,...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)C1CCC=C(C1)c1ccccc1 |c:5,19| Show InChI InChI=1S/C25H29N/c1-3-9-22(10-4-1)24-15-18-26(19-16-24)17-14-21-8-7-13-25(20-21)23-11-5-2-6-12-23/h1-6,9-13,15,21H,7-8,14,16-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	635	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037681 (4-Phenyl-1-(4-phenyl-cyclohex-3-enylmethyl)-1,2,3,...) Show SMILES C(C1CCC(=CC1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,18| Show InChI InChI=1S/C24H27N/c1-3-7-21(8-4-1)23-13-11-20(12-14-23)19-25-17-15-24(16-18-25)22-9-5-2-6-10-22/h1-10,13,15,20H,11-12,14,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037678 (4-Phenyl-1-[(R)-3-(4-trifluoromethyl-phenyl)-cyclo...) Show SMILES FC(F)(F)c1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 |c:20,t:11| Show InChI InChI=1S/C25H26F3N/c26-25(27,28)24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-29-15-13-22(14-16-29)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037676 (4-Phenyl-1-(2-phenyl-cyclohex-2-enylmethyl)-1,2,3,...) Show SMILES C(C1CCCC=C1c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:5,18| Show InChI InChI=1S/C24H27N/c1-3-9-20(10-4-1)21-15-17-25(18-16-21)19-23-13-7-8-14-24(23)22-11-5-2-6-12-22/h1-6,9-12,14-15,23H,7-8,13,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037675 (1-[(R)-3-(4-Chloro-phenyl)-cyclohex-3-enylmethyl]-...) Show SMILES Clc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 |c:17,t:8| Show InChI InChI=1S/C24H26ClN/c25-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-26-15-13-22(14-16-26)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50037677 (4-Phenyl-1-(3-phenyl-cyclohex-3-enyl)-1,2,3,6-tetr...) Show SMILES C1CC(CC(=C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 |c:4,17| Show InChI InChI=1S/C23H25N/c1-3-8-19(9-4-1)21-14-16-24(17-15-21)23-13-7-12-22(18-23)20-10-5-2-6-11-20/h1-6,8-12,14,23H,7,13,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.				J Med Chem 37: 3523-33 (1994) BindingDB Entry DOI: 10.7270/Q2GT5M68
					More data for this Ligand-Target Pair