Found 76 hits Enz. Inhib. hit(s) with all data for entry = 50006198 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045990
(CHEMBL102070 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)c1cccnc1)c1ccccc1 Show InChI InChI=1S/C27H28N6O2/c1-20-23(10-6-12-30-20)25(18-28)32-13-15-33(16-14-32)26(34)17-24(21-7-3-2-4-8-21)31-27(35)22-9-5-11-29-19-22/h2-12,19,24-25H,13-17H2,1H3,(H,31,35) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50003506
(CHEMBL322184 | CHEMBL545771 | {4-[2-(Benzhydryl-am...)Show SMILES O=C(CNC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1 Show InChI InChI=1S/C26H27N5O/c27-18-24(23-12-7-13-28-19-23)30-14-16-31(17-15-30)25(32)20-29-26(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,19,24,26,29H,14-17,20H2 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046012
(CHEMBL100497 | [4-(3-Benzylamino-3-phenyl-propiony...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N5O/c1-22-25(13-8-14-30-22)27(20-29)32-15-17-33(18-16-32)28(34)19-26(24-11-6-3-7-12-24)31-21-23-9-4-2-5-10-23/h2-14,26-27,31H,15-19,21H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045970
(CHEMBL102918 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N5O2/c1-21-24(13-8-14-30-21)26(20-29)32-15-17-33(18-16-32)27(34)19-25(22-9-4-2-5-10-22)31-28(35)23-11-6-3-7-12-23/h2-14,25-26H,15-19H2,1H3,(H,31,35) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50003473
(CHEMBL317193 | [4-(3,3-Diphenyl-acryloyl)-piperazi...)Show SMILES O=[#6](\[#6]=[#6](/c1ccccc1)-c1ccccc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](C#N)-c1cccnc1 Show InChI InChI=1S/C26H24N4O/c27-19-25(23-12-7-13-28-20-23)29-14-16-30(17-15-29)26(31)18-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18,20,25H,14-17H2 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045982
(CHEMBL103596 | [4-(3-Methylamino-3-phenyl-propiony...)Show SMILES CNC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C22H27N5O/c1-17-19(9-6-10-25-17)21(16-23)26-11-13-27(14-12-26)22(28)15-20(24-2)18-7-4-3-5-8-18/h3-10,20-21,24H,11-15H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046017
((2-Methyl-pyridin-3-yl)-[4-(4,4,4-trifluoro-3-phen...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(c1ccccc1)C(F)(F)F Show InChI InChI=1S/C22H23F3N4O/c1-16-18(8-5-9-27-16)20(15-26)28-10-12-29(13-11-28)21(30)14-19(22(23,24)25)17-6-3-2-4-7-17/h2-9,19-20H,10-14H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045983
(CHEMBL103393 | [3-{4-[Cyano-(2-methyl-pyridin-3-yl...)Show SMILES COC(=O)NC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H26F3N5O3/c1-16-19(4-3-9-29-16)21(15-28)31-10-12-32(13-11-31)22(33)14-20(30-23(34)35-2)17-5-7-18(8-6-17)24(25,26)27/h3-9,20-21H,10-14H2,1-2H3,(H,30,34) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045959
(CHEMBL103476 | {4-[2-(Benzhydryl-amino)-propionyl]...)Show SMILES C[C@H](NC(c1ccccc1)c1ccccc1)C(=O)N1CCN(CC1)C(C#N)c1cccnc1C Show InChI InChI=1S/C28H31N5O/c1-21-25(14-9-15-30-21)26(20-29)32-16-18-33(19-17-32)28(34)22(2)31-27(23-10-5-3-6-11-23)24-12-7-4-8-13-24/h3-15,22,26-27,31H,16-19H2,1-2H3/t22-,26?/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045993
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES CCOC(=O)NC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C24H29N5O3/c1-3-32-24(31)27-21(19-8-5-4-6-9-19)16-23(30)29-14-12-28(13-15-29)22(17-25)20-10-7-11-26-18(20)2/h4-11,21-22H,3,12-16H2,1-2H3,(H,27,31) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045972
((2-Methyl-pyridin-3-yl)-[4-(4,4,4-trifluoro-3-hydr...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(O)(c1ccccc1)C(F)(F)F Show InChI InChI=1S/C22H23F3N4O2/c1-16-18(8-5-9-27-16)19(15-26)28-10-12-29(13-11-28)20(30)14-21(31,22(23,24)25)17-6-3-2-4-7-17/h2-9,19,31H,10-14H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045964
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)Oc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N5O3/c1-21-24(13-8-14-30-21)26(20-29)32-15-17-33(18-16-32)27(34)19-25(22-9-4-2-5-10-22)31-28(35)36-23-11-6-3-7-12-23/h2-14,25-26H,15-19H2,1H3,(H,31,35) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045995
(CHEMBL100641 | [4-(3-Hydroxy-3,3-diphenyl-propiony...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2/c1-21-24(13-8-14-29-21)25(20-28)30-15-17-31(18-16-30)26(32)19-27(33,22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,33H,15-19H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045987
((2-Methyl-pyridin-3-yl)-[4-(3-phenyl-3-pyrrolidin-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(N1CCCC1)c1ccccc1 Show InChI InChI=1S/C25H31N5O/c1-20-22(10-7-11-27-20)24(19-26)29-14-16-30(17-15-29)25(31)18-23(28-12-5-6-13-28)21-8-3-2-4-9-21/h2-4,7-11,23-24H,5-6,12-18H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046007
(CHEMBL103995 | [4-(3-Allylamino-3-phenyl-propionyl...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NCC=C)c1ccccc1 Show InChI InChI=1S/C24H29N5O/c1-3-11-27-22(20-8-5-4-6-9-20)17-24(30)29-15-13-28(14-16-29)23(18-25)21-10-7-12-26-19(21)2/h3-10,12,22-23,27H,1,11,13-17H2,2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045991
(CHEMBL100642 | [4-(3,3-Diphenyl-propionyl)-piperaz...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O/c1-21-24(13-8-14-29-21)26(20-28)30-15-17-31(18-16-30)27(32)19-25(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25-26H,15-19H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046027
(CHEMBL103231 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NS(=O)(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H29N5O3S/c1-21-24(13-8-14-29-21)26(20-28)31-15-17-32(18-16-31)27(33)19-25(22-9-4-2-5-10-22)30-36(34,35)23-11-6-3-7-12-23/h2-14,25-26,30H,15-19H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50003490
(CHEMBL101245 | [4-(3,3-Diphenyl-propionyl)-piperaz...)Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1 Show InChI InChI=1S/C26H26N4O/c27-19-25(23-12-7-13-28-20-23)29-14-16-30(17-15-29)26(31)18-24(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,20,24-25H,14-18H2 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045976
(CHEMBL100809 | N-Benzhydryl-N-(2-{4-[cyano-(2-meth...)Show SMILES CC(=O)N(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N5O2/c1-22-26(14-9-15-31-22)27(20-30)32-16-18-33(19-17-32)28(36)21-34(23(2)35)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25/h3-15,27,29H,16-19,21H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046003
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES COC(=O)N(C)C(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C24H29N5O3/c1-18-20(10-7-11-26-18)22(17-25)28-12-14-29(15-13-28)23(30)16-21(27(2)24(31)32-3)19-8-5-4-6-9-19/h4-11,21-22H,12-16H2,1-3H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046022
(CHEMBL319229 | {4-[3-(Benzyl-methyl-amino)-3-pheny...)Show SMILES CN(Cc1ccccc1)C(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C29H33N5O/c1-23-26(14-9-15-31-23)28(21-30)33-16-18-34(19-17-33)29(35)20-27(25-12-7-4-8-13-25)32(2)22-24-10-5-3-6-11-24/h3-15,27-28H,16-20,22H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50003510
(CHEMBL103753 | [4-(3-Hydroxy-3,3-diphenyl-propiony...)Show SMILES OC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H26N4O2/c27-19-24(21-8-7-13-28-20-21)29-14-16-30(17-15-29)25(31)18-26(32,22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-13,20,24,32H,14-18H2 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045965
(CHEMBL265057 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NS(C)(=O)=O)c1ccccc1 Show InChI InChI=1S/C22H27N5O3S/c1-17-19(9-6-10-24-17)21(16-23)26-11-13-27(14-12-26)22(28)15-20(25-31(2,29)30)18-7-4-3-5-8-18/h3-10,20-21,25H,11-15H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046020
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)OCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N5O3/c1-22-25(13-8-14-31-22)27(20-30)33-15-17-34(18-16-33)28(35)19-26(24-11-6-3-7-12-24)32-29(36)37-21-23-9-4-2-5-10-23/h2-14,26-27H,15-19,21H2,1H3,(H,32,36) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045998
(CHEMBL103903 | [4-(3,3-Diphenyl-acryloyl)-piperazi...)Show SMILES [#6]-c1ncccc1-[#6](C#N)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)\[#6]=[#6](\c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C27H26N4O/c1-21-24(13-8-14-29-21)26(20-28)30-15-17-31(18-16-30)27(32)19-25(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,19,26H,15-18H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045968
(CHEMBL319806 | {4-[2-(Diphenyl-methanesulfonyl)-ac...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CS(=O)(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O3S/c1-21-24(13-8-14-29-21)25(19-28)30-15-17-31(18-16-30)26(32)20-35(33,34)27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,27H,15-18,20H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046021
(CHEMBL103560 | [4-(3-Fluoro-2,2-dimethyl-3,3-diphe...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)C(C)(C)C(F)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31FN4O/c1-22-25(15-10-16-32-22)26(21-31)33-17-19-34(20-18-33)27(35)28(2,3)29(30,23-11-6-4-7-12-23)24-13-8-5-9-14-24/h4-16,26H,17-20H2,1-3H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045961
((2-Methyl-pyridin-3-yl)-[4-(3-phenyl-3-phenylamino...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H29N5O/c1-21-24(13-8-14-29-21)26(20-28)31-15-17-32(18-16-31)27(33)19-25(22-9-4-2-5-10-22)30-23-11-6-3-7-12-23/h2-14,25-26,30H,15-19H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046008
(CHEMBL100281 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)c1ccc[nH]c1=O)c1ccccc1 Show InChI InChI=1S/C27H28N6O3/c1-19-21(9-5-11-29-19)24(18-28)32-13-15-33(16-14-32)25(34)17-23(20-7-3-2-4-8-20)31-27(36)22-10-6-12-30-26(22)35/h2-12,23-24H,13-17H2,1H3,(H,30,35)(H,31,36) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046013
(CHEMBL103571 | N-Benzhydryl-N-(2-{4-[cyano-(2-meth...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CN(C=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N5O2/c1-22-25(13-8-14-30-22)26(19-29)31-15-17-32(18-16-31)27(35)20-33(21-34)28(23-9-4-2-5-10-23)24-11-6-3-7-12-24/h2-14,21,26,28H,15-18,20H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046018
(CHEMBL103408 | {4-[2-(Benzhydryl-amino)-propionyl]...)Show SMILES C[C@@H](NC(c1ccccc1)c1ccccc1)C(=O)N1CCN(CC1)C(C#N)c1cccnc1C Show InChI InChI=1S/C28H31N5O/c1-21-25(14-9-15-30-21)26(20-29)32-16-18-33(19-17-32)28(34)22(2)31-27(23-10-5-3-6-11-23)24-12-7-4-8-13-24/h3-15,22,26-27,31H,16-19H2,1-2H3/t22-,26?/m1/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045967
((2-Methyl-pyridin-3-yl)-{4-[3-(2-oxo-pyrrolidin-1-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(N1CCCC1=O)c1ccccc1 Show InChI InChI=1S/C25H29N5O2/c1-19-21(9-5-11-27-19)23(18-26)28-13-15-29(16-14-28)25(32)17-22(20-7-3-2-4-8-20)30-12-6-10-24(30)31/h2-5,7-9,11,22-23H,6,10,12-17H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045977
(CHEMBL102774 | N-(3-{4-[Cyano-(2-methyl-pyridin-3-...)Show SMILES CC(=O)NC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C23H27N5O2/c1-17-20(9-6-10-25-17)22(16-24)27-11-13-28(14-12-27)23(30)15-21(26-18(2)29)19-7-4-3-5-8-19/h3-10,21-22H,11-15H2,1-2H3,(H,26,29) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045963
(CHEMBL100522 | [4-(3-Hydroxy-3-phenyl-3-pyridin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(O)(c1ccccc1)c1cccnc1 Show InChI InChI=1S/C26H27N5O2/c1-20-23(10-6-12-29-20)24(18-27)30-13-15-31(16-14-30)25(32)17-26(33,21-7-3-2-4-8-21)22-9-5-11-28-19-22/h2-12,19,24,33H,13-17H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046006
((2-Methyl-pyridin-3-yl)-[4-(3-phenyl-butyryl)-pipe...)Show SMILES CC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C22H26N4O/c1-17(19-7-4-3-5-8-19)15-22(27)26-13-11-25(12-14-26)21(16-23)20-9-6-10-24-18(20)2/h3-10,17,21H,11-15H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045975
(CHEMBL99795 | {4-[2-(Benzhydryl-amino)-3-hydroxy-p...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)[C@H](CO)NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N5O2/c1-21-24(13-8-14-30-21)26(19-29)32-15-17-33(18-16-32)28(35)25(20-34)31-27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25-27,31,34H,15-18,20H2,1H3/t25-,26?/m0/s1 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045958
(CHEMBL99833 | [4-(3-Hydroxy-3-phenyl-butyryl)-pipe...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(C)(O)c1ccccc1 Show InChI InChI=1S/C22H26N4O2/c1-17-19(9-6-10-24-17)20(16-23)25-11-13-26(14-12-25)21(27)15-22(2,28)18-7-4-3-5-8-18/h3-10,20,28H,11-15H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046015
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES CC(C)COC(=O)NC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C26H33N5O3/c1-19(2)18-34-26(33)29-23(21-8-5-4-6-9-21)16-25(32)31-14-12-30(13-15-31)24(17-27)22-10-7-11-28-20(22)3/h4-11,19,23-24H,12-16,18H2,1-3H3,(H,29,33) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045981
(CHEMBL103773 | {4-[2-(Benzhydryl-amino)-acetyl]-pi...)Show SMILES CCc1ncccc1C(C#N)N1CCN(CC1)C(=O)CNC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N5O/c1-2-25-24(14-9-15-30-25)26(20-29)32-16-18-33(19-17-32)27(34)21-31-28(22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-15,26,28,31H,2,16-19,21H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046019
(CHEMBL100493 | {4-[2-(Benzhydryl-amino)-acetyl]-pi...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CNC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H29N5O/c1-21-24(13-8-14-29-21)25(19-28)31-15-17-32(18-16-31)26(33)20-30-27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,27,30H,15-18,20H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045979
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES COC(=O)NC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1 Show InChI InChI=1S/C23H27N5O3/c1-17-19(9-6-10-25-17)21(16-24)27-11-13-28(14-12-27)22(29)15-20(26-23(30)31-2)18-7-4-3-5-8-18/h3-10,20-21H,11-15H2,1-2H3,(H,26,30) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045969
(CHEMBL103761 | [4-(3-Dibenzylamino-3-phenyl-propio...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(N(Cc1ccccc1)Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H37N5O/c1-28-32(18-11-19-37-28)34(25-36)38-20-22-39(23-21-38)35(41)24-33(31-16-9-4-10-17-31)40(26-29-12-5-2-6-13-29)27-30-14-7-3-8-15-30/h2-19,33-34H,20-24,26-27H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045988
(CHEMBL103180 | [4-(2-Benzhydryloxy-acetyl)-piperaz...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)COC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2/c1-21-24(13-8-14-29-21)25(19-28)30-15-17-31(18-16-30)26(32)20-33-27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,27H,15-18,20H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045956
(CHEMBL103584 | {4-[2-(Diphenyl-methanesulfinyl)-ac...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CS(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2S/c1-21-24(13-8-14-29-21)25(19-28)30-15-17-31(18-16-30)26(32)20-34(33)27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,27H,15-18,20H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045980
(4-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-pipera...)Show SMILES CCOC(=O)C(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H32N4O3/c1-3-37-29(36)30(24-11-6-4-7-12-24,25-13-8-5-9-14-25)21-28(35)34-19-17-33(18-20-34)27(22-31)26-15-10-16-32-23(26)2/h4-16,27H,3,17-21H2,1-2H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045999
(CHEMBL273945 | {4-[2-(9H-Fluoren-9-ylamino)-acetyl...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CNC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C27H27N5O/c1-19-20(11-6-12-29-19)25(17-28)31-13-15-32(16-14-31)26(33)18-30-27-23-9-4-2-7-21(23)22-8-3-5-10-24(22)27/h2-12,25,27,30H,13-16,18H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50003489
(CHEMBL103801 | {4-[3-(Benzhydryl-amino)-propionyl]...)Show SMILES O=C(CCNC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1 Show InChI InChI=1S/C27H29N5O/c28-20-25(24-12-7-14-29-21-24)31-16-18-32(19-17-31)26(33)13-15-30-27(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-12,14,21,25,27,30H,13,15-19H2 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046023
((2-Methyl-pyridin-3-yl)-[4-(4,4,4-trifluoro-3-phen...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)\C=C(/c1ccccc1)C(F)(F)F Show InChI InChI=1S/C22H21F3N4O/c1-16-18(8-5-9-27-16)20(15-26)28-10-12-29(13-11-28)21(30)14-19(22(23,24)25)17-6-3-2-4-7-17/h2-9,14,20H,10-13H2,1H3/b19-14+ | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
In vitro inhibition of PAF-induced platelet aggregation in male rabbits |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50046010
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 Show InChI InChI=1S/C26H33N5O3/c1-19-21(11-8-12-28-19)23(18-27)30-13-15-31(16-14-30)24(32)17-22(20-9-6-5-7-10-20)29-25(33)34-26(2,3)4/h5-12,22-23H,13-17H2,1-4H3,(H,29,33) | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Cavia porcellus) | BDBM50045986
((2-Methyl-pyridin-3-yl)-{4-[3-(2-oxo-oxazolidin-3-...)Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(N1CCOC1=O)c1ccccc1 Show InChI InChI=1S/C24H27N5O3/c1-18-20(8-5-9-26-18)22(17-25)27-10-12-28(13-11-27)23(30)16-21(19-6-3-2-4-7-19)29-14-15-32-24(29)31/h2-9,21-22H,10-16H2,1H3 | MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía, S.A.
Curated by ChEMBL
| Assay Description
Inhibition of PAF-induced platelet aggregation |
J Med Chem 36: 2984-97 (1993)
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ |
More data for this
Ligand-Target Pair | |
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