Compile Data Set for Download or QSAR

Found 58 hits Enz. Inhib. hit(s) with all data for entry = 50005994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50009718 (2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-26-22-15(2)13-16(3)25-24(22)31(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-29-30-28-23/h5-13H,4,14H2,1-3H3,(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043459 (CHEMBL335722 | N-(2-{[4-(2-Ethyl-5,7-dimethyl-imid...) Show SMILES CCCN(C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C34H37N5O3S/c1-5-21-38(32(27-13-9-7-10-14-27)34(40)37-43(41,42)29-15-11-8-12-16-29)28-19-17-26(18-20-28)23-39-30(6-2)36-31-24(3)22-25(4)35-33(31)39/h7-20,22,32H,5-6,21,23H2,1-4H3,(H,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043463 (CHEMBL337007 | N-(2-{Ethyl-[4-(2-ethyl-5,7-dimethy...) Show SMILES CCN(C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C33H35N5O3S/c1-5-29-35-30-23(3)21-24(4)34-32(30)38(29)22-25-17-19-27(20-18-25)37(6-2)31(26-13-9-7-10-14-26)33(39)36-42(40,41)28-15-11-8-12-16-28/h7-21,31H,5-6,22H2,1-4H3,(H,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043451 (CHEMBL337006 | N-(2-{Allyl-[4-(2-ethyl-5,7-dimethy...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H35N5O3S/c1-5-21-38(32(27-13-9-7-10-14-27)34(40)37-43(41,42)29-15-11-8-12-16-29)28-19-17-26(18-20-28)23-39-30(6-2)36-31-24(3)22-25(4)35-33(31)39/h5,7-20,22,32H,1,6,21,23H2,2-4H3,(H,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043457 (CHEMBL135346 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C27H30N4O2/c1-5-23-29-24-18(3)16-19(4)28-26(24)31(23)17-20-12-14-22(15-13-20)30(6-2)25(27(32)33)21-10-8-7-9-11-21/h7-16,25H,5-6,17H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043470 (CHEMBL336738 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h7-15,17,26H,5-6,16,18H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043469 (CHEMBL135089 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C28H30N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h5,7-15,17,26H,1,6,16,18H2,2-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043475 (CHEMBL135345 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-28-23-17(2)15-18(3)27-25(23)30(22)16-19-11-13-21(14-12-19)29(4)24(26(31)32)20-9-7-6-8-10-20/h6-15,24H,5,16H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043473 (CHEMBL335289 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)15-20(5)29-27(25)32(24)17-21-13-14-23(18(3)16-21)31(7-2)26(28(33)34)22-11-9-8-10-12-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043462 (CHEMBL335066 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C29H34N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h8-14,16-17,27H,6-7,15,18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043456 (CHEMBL337217 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(c1nnn[nH]1)c1ccccc1 Show InChI InChI=1S/C26H28N8/c1-5-22-28-23-17(2)15-18(3)27-26(23)34(22)16-19-11-13-21(14-12-19)33(4)24(25-29-31-32-30-25)20-9-7-6-8-10-20/h6-15,24H,5,16H2,1-4H3,(H,29,30,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043467 (CHEMBL136028 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC(C)C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H34N4O2/c1-6-25-31-26-20(4)16-21(5)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-19(2)3)27(29(34)35)23-10-8-7-9-11-23/h7-16,19,27H,6,17-18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043455 (CHEMBL424465 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2C)c(C)c1 Show InChI InChI=1S/C27H30N4O2/c1-6-23-30-24-18(4)13-19(5)28-26(24)31(23)15-20-11-12-22(17(3)14-20)29-25(27(32)33)21-10-8-7-9-16(21)2/h7-14,25,29H,6,15H2,1-5H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043460 (CHEMBL134286 | {Cyclopropylmethyl-[4-(2-ethyl-5,7-...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c1-4-25-31-26-19(2)16-20(3)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-21-10-11-21)27(29(34)35)23-8-6-5-7-9-23/h5-9,12-16,21,27H,4,10-11,17-18H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043476 (CHEMBL336773 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C29H32N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h6,8-14,16-17,27H,1,7,15,18H2,2-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50009714 (CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) Show SMILES CCCCC1=NC(Cl)C(CO)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |t:4| Show InChI InChI=1S/C22H25ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,19,21,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043454 (CHEMBL134491 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1cccc(C)c1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)16-20(5)29-27(25)32(24)17-21-11-13-23(14-12-21)31(7-2)26(28(33)34)22-10-8-9-18(3)15-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043466 (CHEMBL424643 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(C)C(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C27H30N4O2/c1-6-23-29-24-18(3)14-19(4)28-26(24)31(23)16-20-12-13-22(17(2)15-20)30(5)25(27(32)33)21-10-8-7-9-11-21/h7-15,25H,6,16H2,1-5H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043453 (CHEMBL135929 | {sec-Butyl-[4-(2-ethyl-5,7-dimethyl...) Show SMILES CCC(C)N(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C29H34N4O2/c1-6-21(5)33(27(29(34)35)23-11-9-8-10-12-23)24-15-13-22(14-16-24)18-32-25(7-2)31-26-19(3)17-20(4)30-28(26)32/h8-17,21,27H,6-7,18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043465 (CHEMBL334832 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2C)c(C)c1 Show InChI InChI=1S/C30H34N4O2/c1-7-15-33(28(30(35)36)24-12-10-9-11-19(24)3)25-14-13-23(17-20(25)4)18-34-26(8-2)32-27-21(5)16-22(6)31-29(27)34/h7,9-14,16-17,28H,1,8,15,18H2,2-6H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043468 ((2,5-Difluoro-phenyl)-{ethyl-[4-(2-ethyl-5,7-dimet...) Show SMILES CCN(C(C(O)=O)c1cc(F)ccc1F)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C27H28F2N4O2/c1-5-23-31-24-16(3)13-17(4)30-26(24)33(23)15-18-7-10-20(11-8-18)32(6-2)25(27(34)35)21-14-19(28)9-12-22(21)29/h7-14,25H,5-6,15H2,1-4H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043461 (CHEMBL336808 | {Butyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C29H34N4O2/c1-5-7-17-32(27(29(34)35)23-11-9-8-10-12-23)24-15-13-22(14-16-24)19-33-25(6-2)31-26-20(3)18-21(4)30-28(26)33/h8-16,18,27H,5-7,17,19H2,1-4H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043471 ((2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1cc(F)ccc1F Show InChI InChI=1S/C26H26F2N4O2/c1-5-22-30-23-15(2)12-16(3)29-25(23)32(22)14-17-6-9-19(10-7-17)31(4)24(26(33)34)20-13-18(27)8-11-21(20)28/h6-13,24H,5,14H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043477 (CHEMBL135704 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-29-23-17(3)13-18(4)27-25(23)30(22)15-19-11-12-21(16(2)14-19)28-24(26(31)32)20-9-7-6-8-10-20/h6-14,24,28H,5,15H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043472 (CHEMBL335514 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H26N4O2/c1-4-21-28-22-16(2)14-17(3)26-24(22)29(21)15-18-10-12-20(13-11-18)27-23(25(30)31)19-8-6-5-7-9-19/h5-14,23,27H,4,15H2,1-3H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043463 (CHEMBL337007 | N-(2-{Ethyl-[4-(2-ethyl-5,7-dimethy...) Show SMILES CCN(C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C33H35N5O3S/c1-5-29-35-30-23(3)21-24(4)34-32(30)38(29)22-25-17-19-27(20-18-25)37(6-2)31(26-13-9-7-10-14-26)33(39)36-42(40,41)28-15-11-8-12-16-28/h7-21,31H,5-6,22H2,1-4H3,(H,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043452 (CHEMBL337663 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(O)=O)c1cc(F)ccc1F Show InChI InChI=1S/C28H28F2N4O2/c1-5-13-33(26(28(35)36)22-15-20(29)9-12-23(22)30)21-10-7-19(8-11-21)16-34-24(6-2)32-25-17(3)14-18(4)31-27(25)34/h5,7-12,14-15,26H,1,6,13,16H2,2-4H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043467 (CHEMBL136028 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC(C)C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H34N4O2/c1-6-25-31-26-20(4)16-21(5)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-19(2)3)27(29(34)35)23-10-8-7-9-11-23/h7-16,19,27H,6,17-18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043458 ((2-Chloro-phenyl)-{ethyl-[4-(2-ethyl-5,7-dimethyl-...) Show SMILES CCN(C(C(O)=O)c1ccccc1Cl)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C27H29ClN4O2/c1-5-23-30-24-17(3)15-18(4)29-26(24)32(23)16-19-11-13-20(14-12-19)31(6-2)25(27(33)34)21-9-7-8-10-22(21)28/h7-15,25H,5-6,16H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043459 (CHEMBL335722 | N-(2-{[4-(2-Ethyl-5,7-dimethyl-imid...) Show SMILES CCCN(C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C34H37N5O3S/c1-5-21-38(32(27-13-9-7-10-14-27)34(40)37-43(41,42)29-15-11-8-12-16-29)28-19-17-26(18-20-28)23-39-30(6-2)36-31-24(3)22-25(4)35-33(31)39/h7-20,22,32H,5-6,21,23H2,1-4H3,(H,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043469 (CHEMBL135089 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C28H30N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h5,7-15,17,26H,1,6,16,18H2,2-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043470 (CHEMBL336738 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-5-16-31(26(28(33)34)22-10-8-7-9-11-22)23-14-12-21(13-15-23)18-32-24(6-2)30-25-19(3)17-20(4)29-27(25)32/h7-15,17,26H,5-6,16,18H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043461 (CHEMBL336808 | {Butyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C29H34N4O2/c1-5-7-17-32(27(29(34)35)23-11-9-8-10-12-23)24-15-13-22(14-16-24)19-33-25(6-2)31-26-20(3)18-21(4)30-28(26)33/h8-16,18,27H,5-7,17,19H2,1-4H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043457 (CHEMBL135346 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C27H30N4O2/c1-5-23-29-24-18(3)16-19(4)28-26(24)31(23)17-20-12-14-22(15-13-20)30(6-2)25(27(32)33)21-10-8-7-9-11-21/h7-16,25H,5-6,17H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043464 ((3,5-Bis-trifluoromethyl-phenyl)-[4-(2-ethyl-5,7-d...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C27H24F6N4O2/c1-4-21-36-22-14(2)9-15(3)34-24(22)37(21)13-16-5-7-20(8-6-16)35-23(25(38)39)17-10-18(26(28,29)30)12-19(11-17)27(31,32)33/h5-12,23,35H,4,13H2,1-3H3,(H,38,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043453 (CHEMBL135929 | {sec-Butyl-[4-(2-ethyl-5,7-dimethyl...) Show SMILES CCC(C)N(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C29H34N4O2/c1-6-21(5)33(27(29(34)35)23-11-9-8-10-12-23)24-15-13-22(14-16-24)18-32-25(7-2)31-26-19(3)17-20(4)30-28(26)32/h8-17,21,27H,6-7,18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50043474 ((3,5-Bis-trifluoromethyl-phenyl)-{ethyl-[4-(2-ethy...) Show SMILES CCN(C(C(O)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C29H28F6N4O2/c1-5-23-37-24-16(3)11-17(4)36-26(24)39(23)15-18-7-9-22(10-8-18)38(6-2)25(27(40)41)19-12-20(28(30,31)32)14-21(13-19)29(33,34)35/h7-14,25H,5-6,15H2,1-4H3,(H,40,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043454 (CHEMBL134491 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1cccc(C)c1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)16-20(5)29-27(25)32(24)17-21-11-13-23(14-12-21)31(7-2)26(28(33)34)22-10-8-9-18(3)15-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043460 (CHEMBL134286 | {Cyclopropylmethyl-[4-(2-ethyl-5,7-...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC1CC1)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c1-4-25-31-26-19(2)16-20(3)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-21-10-11-21)27(29(34)35)23-8-6-5-7-9-23/h5-9,12-16,21,27H,4,10-11,17-18H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043451 (CHEMBL337006 | N-(2-{Allyl-[4-(2-ethyl-5,7-dimethy...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(=O)NS(=O)(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H35N5O3S/c1-5-21-38(32(27-13-9-7-10-14-27)34(40)37-43(41,42)29-15-11-8-12-16-29)28-19-17-26(18-20-28)23-39-30(6-2)36-31-24(3)22-25(4)35-33(31)39/h5,7-20,22,32H,1,6,21,23H2,2-4H3,(H,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043475 (CHEMBL135345 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1ccccc1 Show InChI InChI=1S/C26H28N4O2/c1-5-22-28-23-17(2)15-18(3)27-25(23)30(22)16-19-11-13-21(14-12-19)29(4)24(26(31)32)20-9-7-6-8-10-20/h6-15,24H,5,16H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043476 (CHEMBL336773 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C29H32N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h6,8-14,16-17,27H,1,7,15,18H2,2-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043462 (CHEMBL335066 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...) Show SMILES CCCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C29H34N4O2/c1-6-15-32(27(29(34)35)23-11-9-8-10-12-23)24-14-13-22(17-19(24)3)18-33-25(7-2)31-26-20(4)16-21(5)30-28(26)33/h8-14,16-17,27H,6-7,15,18H2,1-5H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043464 ((3,5-Bis-trifluoromethyl-phenyl)-[4-(2-ethyl-5,7-d...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C27H24F6N4O2/c1-4-21-36-22-14(2)9-15(3)34-24(22)37(21)13-16-5-7-20(8-6-16)35-23(25(38)39)17-10-18(26(28,29)30)12-19(11-17)27(31,32)33/h5-12,23,35H,4,13H2,1-3H3,(H,38,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043473 (CHEMBL335289 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1C Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)15-20(5)29-27(25)32(24)17-21-13-14-23(18(3)16-21)31(7-2)26(28(33)34)22-11-9-8-10-12-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043452 (CHEMBL337663 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(O)=O)c1cc(F)ccc1F Show InChI InChI=1S/C28H28F2N4O2/c1-5-13-33(26(28(35)36)22-15-20(29)9-12-23(22)30)21-10-7-19(8-11-21)16-34-24(6-2)32-25-17(3)14-18(4)31-27(25)34/h5,7-12,14-15,26H,1,6,13,16H2,2-4H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043468 ((2,5-Difluoro-phenyl)-{ethyl-[4-(2-ethyl-5,7-dimet...) Show SMILES CCN(C(C(O)=O)c1cc(F)ccc1F)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C27H28F2N4O2/c1-5-23-31-24-16(3)13-17(4)30-26(24)33(23)15-18-7-10-20(11-8-18)32(6-2)25(27(34)35)21-14-19(28)9-12-22(21)29/h7-14,25H,5-6,15H2,1-4H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50009718 (2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-26-22-15(2)13-16(3)25-24(22)31(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-29-30-28-23/h5-13H,4,14H2,1-3H3,(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043471 ((2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-im...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1cc(F)ccc1F Show InChI InChI=1S/C26H26F2N4O2/c1-5-22-30-23-15(2)12-16(3)29-25(23)32(22)14-17-6-9-19(10-7-17)31(4)24(26(33)34)20-13-18(27)8-11-21(20)28/h6-13,24H,5,14H2,1-4H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50043465 (CHEMBL334832 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC=C)C(C(O)=O)c2ccccc2C)c(C)c1 Show InChI InChI=1S/C30H34N4O2/c1-7-15-33(28(30(35)36)24-12-10-9-11-19(24)3)25-14-13-23(17-20(25)4)18-34-26(8-2)32-27-21(5)16-22(6)31-29(27)34/h7,9-14,16-17,28H,1,8,15,18H2,2-6H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.				J Med Chem 36: 4239-49 (1994) BindingDB Entry DOI: 10.7270/Q22V2F6P
					More data for this Ligand-Target Pair

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