Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041617 ((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041616 ((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041617 ((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 14.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041622 ((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-5-hydroxy-3-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041618 ((1R,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041621 ((1R,2R,3S)-1,3-Bis-(4-methoxy-phenyl)-indan-2-carb...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 422 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041622 ((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-5-hydroxy-3-(4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 483 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041618 ((1R,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 757 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041616 ((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041621 ((1R,2R,3S)-1,3-Bis-(4-methoxy-phenyl)-indan-2-carb...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041619 ((1S,2S,3R)-1-(4-Methoxy-phenyl)-3-phenyl-indan-2-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human Endothelin A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50041620 ((1R,2R,3S)-1,3-Diphenyl-indan-2-carboxylic acid | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-A receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041620 ((1R,2R,3S)-1,3-Diphenyl-indan-2-carboxylic acid | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (Homo sapiens (Human)) | BDBM50041619 ((1S,2S,3R)-1-(4-Methoxy-phenyl)-3-phenyl-indan-2-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of [125I]-ET-1 binding to cloned human ET-B receptor | J Med Chem 37: 1553-7 (1994) BindingDB Entry DOI: 10.7270/Q2154G2V | |||||||||||
More data for this Ligand-Target Pair |