Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50005954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042876 (CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...) Show SMILES OC(=O)c1ccc(nc1)-c1ccc(cn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042876 (CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...) Show SMILES OC(=O)c1ccc(nc1)-c1ccc(cn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042873 (5'-(4-Ethoxy-phenylcarbamoyl)-[2,2']bipyridinyl-5-...) Show SMILES CCOc1ccc(NC(=O)c2ccc(nc2)-c2ccc(cn2)C(O)=O)cc1 Show InChI InChI=1S/C20H17N3O4/c1-2-27-16-7-5-15(6-8-16)23-19(24)13-3-9-17(21-11-13)18-10-4-14(12-22-18)20(25)26/h3-12H,2H2,1H3,(H,23,24)(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042872 (3-phenylsulfonamidocarbonyl-6-(5-phenylsulfonamido...) Show SMILES O=C(NS(=O)(=O)c1ccccc1)c1ccc(nc1)-c1ccc(cn1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C24H18N4O6S2/c29-23(27-35(31,32)19-7-3-1-4-8-19)17-11-13-21(25-15-17)22-14-12-18(16-26-22)24(30)28-36(33,34)20-9-5-2-6-10-20/h1-16H,(H,27,29)(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) Show SMILES OC(=O)c1ccc(nc1)C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042875 (CHEMBL125345 | Potassium; [2,2']bipyridinyl-5-carb...) Show SMILES [O-]C(=O)c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-5-10(13-7-8)9-3-1-2-6-12-9/h1-7H,(H,14,15)/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042877 (CHEMBL420149 | N-([2,2']Bipyridinyl-5-carbonyl)-be...) Show SMILES O=C(NS(=O)(=O)c1ccccc1)c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C17H13N3O3S/c21-17(20-24(22,23)14-6-2-1-3-7-14)13-9-10-16(19-12-13)15-8-4-5-11-18-15/h1-12H,(H,20,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50042874 (2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl ...) Show SMILES c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM50000407 (2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...) Show SMILES OC(=O)c1ccccn1 Show InChI InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
Zeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna				J Med Chem 36: 3853-8 (1994) BindingDB Entry DOI: 10.7270/Q2RJ4HJV
					More data for this Ligand-Target Pair