BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with all data for entry = 50044152
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11464 ((2S,3S)-2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)p...) Show SMILES CC[C@H](C)[C@H](N)C(=O)N1CCSC1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CHUV-UNIL Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				J Med Chem 57: 2197-212 (2014) Article DOI: 10.1021/jm400658e BindingDB Entry DOI: 10.7270/Q2TB18F1
CHUV-UNIL Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11695 ((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
CHUV-UNIL Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				J Med Chem 57: 2197-212 (2014) Article DOI: 10.1021/jm400658e BindingDB Entry DOI: 10.7270/Q2TB18F1
CHUV-UNIL Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11162 ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
CHUV-UNIL Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				J Med Chem 57: 2197-212 (2014) Article DOI: 10.1021/jm400658e BindingDB Entry DOI: 10.7270/Q2TB18F1
CHUV-UNIL Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11113 (6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
CHUV-UNIL Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				J Med Chem 57: 2197-212 (2014) Article DOI: 10.1021/jm400658e BindingDB Entry DOI: 10.7270/Q2TB18F1
CHUV-UNIL Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50225074 ((1S,3S,5S)-2-[(S)-2-amino-2-(3-hydroxy-adamantan-1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
CHUV-UNIL Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				J Med Chem 57: 2197-212 (2014) Article DOI: 10.1021/jm400658e BindingDB Entry DOI: 10.7270/Q2TB18F1
CHUV-UNIL Curated by ChEMBL					More data for this Ligand-Target Pair