Compile Data Set for Download or QSAR

Found 82 hits Enz. Inhib. hit(s) with all data for entry = 50044168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50007606 (CHEMBL3238280) Show SMILES C[C@](O)(COc1ccc(Br)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17BrN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007591 (CHEMBL3238292) Show SMILES C[C@](O)(COc1ccc(cc1F)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007595 (CHEMBL3233069) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN2O4/c1-20(25,12-27-18-7-6-14(26-2)10-16(18)21)19(24)23-9-8-15-13(11-22)4-3-5-17(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007590 (CHEMBL3238291) Show SMILES C[C@](O)(COc1ccc(cc1Br)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16BrN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007596 (CHEMBL3233070) Show SMILES C[C@](O)(COc1ccc(Cl)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16ClFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007587 (CHEMBL3238288) Show SMILES C[C@](O)(COc1ccc(F)cc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-15(21)9-14(18)11-23)19(25)24-8-7-16-13(10-22)3-2-4-17(16)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007597 (CHEMBL3233071) Show SMILES C[C@](O)(COc1ccc(Cl)cc1Cl)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16Cl2N2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007602 (CHEMBL3238276) Show SMILES C[C@](O)(COc1ccccc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-17-8-3-2-6-15(17)20)18(23)22-10-9-14-13(11-21)5-4-7-16(14)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007589 (CHEMBL3238290) Show SMILES Cc1cc(F)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H19FN2O3/c1-13-10-15(21)6-7-18(13)26-12-20(2,25)19(24)23-9-8-16-14(11-22)4-3-5-17(16)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007588 (CHEMBL3238289) Show SMILES C[C@](O)(COc1ccc(F)cc1Br)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(21)9-15(17)20)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007600 (CHEMBL3238274) Show SMILES C[C@](O)(COc1ccc(F)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007586 (CHEMBL3238287) Show SMILES C[C@](O)(COc1ccccc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-18-8-3-2-5-15(18)12-22)19(24)23-10-9-16-14(11-21)6-4-7-17(16)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007584 (CHEMBL3238285) Show SMILES C[C@](O)(COc1ccc(cc1)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-16-7-5-14(11-21)6-8-16)19(24)23-10-9-17-15(12-22)3-2-4-18(17)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007592 (CHEMBL3238293) Show SMILES COc1cc(ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N)C#N |r| Show InChI InChI=1S/C21H19N3O4/c1-21(26,13-28-18-7-6-14(11-22)10-19(18)27-2)20(25)24-9-8-16-15(12-23)4-3-5-17(16)24/h3-7,10,26H,8-9,13H2,1-2H3/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007607 (CHEMBL3238281) Show SMILES C[C@](O)(COc1ccc(cc1)C(F)(F)F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17F3N2O3/c1-19(27,12-28-15-7-5-14(6-8-15)20(21,22)23)18(26)25-10-9-16-13(11-24)3-2-4-17(16)25/h2-8,27H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007601 (CHEMBL3238275) Show SMILES C[C@](O)(COc1cccc(F)c1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-6-3-5-14(20)10-15)18(23)22-9-8-16-13(11-21)4-2-7-17(16)22/h2-7,10,24H,8-9,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007603 (CHEMBL3238277) Show SMILES C[C@](O)(COc1ccc(Cl)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007598 (CHEMBL3233072) Show SMILES C[C@](O)(COc1ccc(Br)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007605 (CHEMBL3238279) Show SMILES C[C@](O)(COc1ccccc1Cl)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-17-8-3-2-6-15(17)20)18(23)22-10-9-14-13(11-21)5-4-7-16(14)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007585 (CHEMBL3238286) Show SMILES C[C@](O)(COc1ccccc1C(F)(F)F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17F3N2O3/c1-19(27,12-28-17-8-3-2-6-15(17)20(21,22)23)18(26)25-10-9-14-13(11-24)5-4-7-16(14)25/h2-8,27H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007599 (CHEMBL3238273) Show SMILES C[C@](O)(COc1ccccc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H18N2O3/c1-19(23,13-24-15-7-3-2-4-8-15)18(22)21-11-10-16-14(12-20)6-5-9-17(16)21/h2-9,23H,10-11,13H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007604 (CHEMBL3238278) Show SMILES C[C@](O)(COc1cccc(Cl)c1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-15-6-3-5-14(20)10-15)18(23)22-9-8-16-13(11-21)4-2-7-17(16)22/h2-7,10,24H,8-9,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007609 (CHEMBL3238283) Show SMILES COC(=O)c1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)cc1 |r| Show InChI InChI=1S/C21H20N2O5/c1-21(26,13-28-16-8-6-14(7-9-16)19(24)27-2)20(25)23-11-10-17-15(12-22)4-3-5-18(17)23/h3-9,26H,10-11,13H2,1-2H3/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007608 (CHEMBL3238282) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)cc1 |r| Show InChI InChI=1S/C20H20N2O4/c1-20(24,13-26-16-8-6-15(25-2)7-9-16)19(23)22-11-10-17-14(12-21)4-3-5-18(17)22/h3-9,24H,10-11,13H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007610 (CHEMBL3238284) Show SMILES C[C@](O)(COc1ccc(cc1)-c1cocn1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C22H19N3O4/c1-22(27,13-29-17-7-5-15(6-8-17)19-12-28-14-24-19)21(26)25-10-9-18-16(11-23)3-2-4-20(18)25/h2-8,12,14,27H,9-10,13H2,1H3/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007593 (CHEMBL3238294) Show SMILES COc1cc(Cl)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H19ClN2O4/c1-20(25,12-27-17-7-6-14(21)10-18(17)26-2)19(24)23-9-8-15-13(11-22)4-3-5-16(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	366	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007594 (CHEMBL3238295) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)c(F)c1 |r| Show InChI InChI=1S/C20H19FN2O4/c1-20(25,12-27-18-7-6-14(26-2)10-16(18)21)19(24)23-9-8-15-13(11-22)4-3-5-17(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50007600 (CHEMBL3238274) Show SMILES C[C@](O)(COc1ccc(F)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human ERG by dofetilide binding assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007584 (CHEMBL3238285) Show SMILES C[C@](O)(COc1ccc(cc1)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-16-7-5-14(11-21)6-8-16)19(24)23-10-9-17-15(12-22)3-2-4-18(17)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007585 (CHEMBL3238286) Show SMILES C[C@](O)(COc1ccccc1C(F)(F)F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17F3N2O3/c1-19(27,12-28-17-8-3-2-6-15(17)20(21,22)23)18(26)25-10-9-14-13(11-24)5-4-7-16(14)25/h2-8,27H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007586 (CHEMBL3238287) Show SMILES C[C@](O)(COc1ccccc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-18-8-3-2-5-15(18)12-22)19(24)23-10-9-16-14(11-21)6-4-7-17(16)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007587 (CHEMBL3238288) Show SMILES C[C@](O)(COc1ccc(F)cc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-15(21)9-14(18)11-23)19(25)24-8-7-16-13(10-22)3-2-4-17(16)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0740	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007588 (CHEMBL3238289) Show SMILES C[C@](O)(COc1ccc(F)cc1Br)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(21)9-15(17)20)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007589 (CHEMBL3238290) Show SMILES Cc1cc(F)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H19FN2O3/c1-13-10-15(21)6-7-18(13)26-12-20(2,25)19(24)23-9-8-16-14(11-22)4-3-5-17(16)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007590 (CHEMBL3238291) Show SMILES C[C@](O)(COc1ccc(cc1Br)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16BrN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007591 (CHEMBL3238292) Show SMILES C[C@](O)(COc1ccc(cc1F)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0390	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007592 (CHEMBL3238293) Show SMILES COc1cc(ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N)C#N |r| Show InChI InChI=1S/C21H19N3O4/c1-21(26,13-28-18-7-6-14(11-22)10-19(18)27-2)20(25)24-9-8-16-15(12-23)4-3-5-17(16)24/h3-7,10,26H,8-9,13H2,1-2H3/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007593 (CHEMBL3238294) Show SMILES COc1cc(Cl)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H19ClN2O4/c1-20(25,12-27-17-7-6-14(21)10-18(17)26-2)19(24)23-9-8-15-13(11-22)4-3-5-16(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007594 (CHEMBL3238295) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)c(F)c1 |r| Show InChI InChI=1S/C20H19FN2O4/c1-20(25,12-27-18-7-6-14(26-2)10-16(18)21)19(24)23-9-8-15-13(11-22)4-3-5-17(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007595 (CHEMBL3233069) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN2O4/c1-20(25,12-27-18-7-6-14(26-2)10-16(18)21)19(24)23-9-8-15-13(11-22)4-3-5-17(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.610	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007596 (CHEMBL3233070) Show SMILES C[C@](O)(COc1ccc(Cl)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16ClFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007597 (CHEMBL3233071) Show SMILES C[C@](O)(COc1ccc(Cl)cc1Cl)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16Cl2N2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007598 (CHEMBL3233072) Show SMILES C[C@](O)(COc1ccc(Br)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human AR expressed in CV1 cells after 17 hrs by luciferase reporter gene assay				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007599 (CHEMBL3238273) Show SMILES C[C@](O)(COc1ccccc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H18N2O3/c1-19(23,13-24-15-7-3-2-4-8-15)18(22)21-11-10-16-14(12-20)6-5-9-17(16)21/h2-9,23H,10-11,13H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007600 (CHEMBL3238274) Show SMILES C[C@](O)(COc1ccc(F)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007601 (CHEMBL3238275) Show SMILES C[C@](O)(COc1cccc(F)c1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-6-3-5-14(20)10-15)18(23)22-9-8-16-13(11-21)4-2-7-17(16)22/h2-7,10,24H,8-9,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007602 (CHEMBL3238276) Show SMILES C[C@](O)(COc1ccccc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-17-8-3-2-6-15(17)20)18(23)22-10-9-14-13(11-21)5-4-7-16(14)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007603 (CHEMBL3238277) Show SMILES C[C@](O)(COc1ccc(Cl)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	172	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007604 (CHEMBL3238278) Show SMILES C[C@](O)(COc1cccc(Cl)c1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-15-6-3-5-14(20)10-15)18(23)22-9-8-16-13(11-21)4-2-7-17(16)22/h2-7,10,24H,8-9,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007605 (CHEMBL3238279) Show SMILES C[C@](O)(COc1ccccc1Cl)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-17-8-3-2-6-15(17)20)18(23)22-10-9-14-13(11-21)5-4-7-16(14)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.82E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human AR NTD (1 to 561 aa) expressed in CV1 cells coexpressing human AR-LBD (644-919 aa) assessed as N/C-termini interaction by a...				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair

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