Found 43 hits Enz. Inhib. hit(s) with all data for entry = 50007286 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060785
(CHEMBL268095 | [D or LAgl (hydroxyacetic acid)4]ac...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@@H](NC(=O)CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)37-63(73(105)90-62(18-11-12-35-85-47(3)4)81(113)98-36-14-19-69(98)79(111)86-48(5)71(83)104)91-75(107)66(40-53-23-30-60(31-24-53)87-49(6)100)93-77(109)67(41-54-25-32-61(33-26-54)88-50(7)101)95-80(112)72(96-70(103)45-99)97-78(110)68(43-56-15-13-34-84-44-56)94-76(108)65(39-52-21-28-59(82)29-22-52)92-74(106)64(89-51(8)102)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-69,72,85,99H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,83,104)(H,86,111)(H,87,100)(H,88,101)(H,89,102)(H,90,105)(H,91,107)(H,92,106)(H,93,109)(H,94,108)(H,95,112)(H,96,103)(H,97,110)/t48-,62+,63+,64-,65-,66-,67+,68-,69-,72+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0560 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060807
(CHEMBL216519 | [L-3Pal3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H102ClN15O14/c1-46(2)37-63(72(102)89-62(18-11-12-35-84-47(3)4)80(110)96-36-14-19-70(96)79(109)85-48(5)71(82)101)90-74(104)66(40-53-23-30-60(31-24-53)86-49(6)98)92-76(106)67(41-54-25-32-61(33-26-54)87-50(7)99)94-78(108)69(45-97)95-77(107)68(43-56-15-13-34-83-44-56)93-75(105)65(39-52-21-28-59(81)29-22-52)91-73(103)64(88-51(8)100)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,84,97H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,82,101)(H,85,109)(H,86,98)(H,87,99)(H,88,100)(H,89,102)(H,90,104)(H,91,103)(H,92,106)(H,93,105)(H,94,108)(H,95,107)/t48-,62+,63+,64-,65-,66-,67+,68+,69+,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060786
(CHEMBL415351 | [Ac-D2Nal1,D4Cpa2,D3Pal3,4Aph5(Ac),...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H102ClN15O14/c1-46(2)37-63(72(102)89-62(18-11-12-35-84-47(3)4)80(110)96-36-14-19-70(96)79(109)85-48(5)71(82)101)90-74(104)66(40-53-23-30-60(31-24-53)86-49(6)98)92-76(106)67(41-54-25-32-61(33-26-54)87-50(7)99)94-78(108)69(45-97)95-77(107)68(43-56-15-13-34-83-44-56)93-75(105)65(39-52-21-28-59(81)29-22-52)91-73(103)64(88-51(8)100)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,84,97H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,82,101)(H,85,109)(H,86,98)(H,87,99)(H,88,100)(H,89,102)(H,90,104)(H,91,103)(H,92,106)(H,93,105)(H,94,108)(H,95,107)/t48-,62+,63+,64-,65-,66-,67+,68-,69+,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060776
(CHEMBL262825 | [D/LAgl (4-hydroxybenzoyl)5]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1ccc(O)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C78H98ClN15O15/c1-44(2)36-60(70(101)86-59(17-10-11-34-82-45(3)4)78(109)94-35-13-18-66(94)76(107)83-46(5)67(80)99)87-73(104)63(39-50-22-29-57(30-23-50)84-47(6)96)90-77(108)68(92-69(100)54-25-31-58(98)32-26-54)93-75(106)65(43-95)91-74(105)64(41-52-14-12-33-81-42-52)89-72(103)62(38-49-20-27-56(79)28-21-49)88-71(102)61(85-48(7)97)40-51-19-24-53-15-8-9-16-55(53)37-51/h8-9,12,14-16,19-33,37,42,44-46,59-66,68,82,95,98H,10-11,13,17-18,34-36,38-41,43H2,1-7H3,(H2,80,99)(H,83,107)(H,84,96)(H,85,97)(H,86,101)(H,87,104)(H,88,102)(H,89,103)(H,90,108)(H,91,105)(H,92,100)(H,93,106)/t46-,59+,60+,61-,62-,63-,64-,65+,66-,68-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060779
(CHEMBL407316 | [L or DAgl (hydroxyacetic acid)4]ac...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](NC(=O)CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)37-63(73(105)90-62(18-11-12-35-85-47(3)4)81(113)98-36-14-19-69(98)79(111)86-48(5)71(83)104)91-75(107)66(40-53-23-30-60(31-24-53)87-49(6)100)93-77(109)67(41-54-25-32-61(33-26-54)88-50(7)101)95-80(112)72(96-70(103)45-99)97-78(110)68(43-56-15-13-34-84-44-56)94-76(108)65(39-52-21-28-59(82)29-22-52)92-74(106)64(89-51(8)102)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-69,72,85,99H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,83,104)(H,86,111)(H,87,100)(H,88,101)(H,89,102)(H,90,105)(H,91,107)(H,92,106)(H,93,109)(H,94,108)(H,95,112)(H,96,103)(H,97,110)/t48-,62+,63+,64-,65-,66-,67+,68-,69-,72-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060811
(CHEMBL412472 | [Ac-D or LAgl (Me,2-naphthoyl)1]acy...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](NC(C)=O)N(C)C(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-73(105)64(40-53-23-31-60(32-24-53)87-49(6)100)92-74(106)65(41-54-25-33-61(34-26-54)88-50(7)101)94-77(109)68(45-99)96-76(108)67(42-55-16-14-35-84-44-55)93-75(107)66(39-52-21-29-59(82)30-22-52)95-79(111)71(89-51(8)102)97(9)80(112)58-28-27-56-17-10-11-18-57(56)43-58/h10-11,14,16-18,21-35,43-44,46-48,62-69,71,85,99H,12-13,15,19-20,36-42,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,107)(H,94,109)(H,95,111)(H,96,108)/t48-,62+,63+,64-,65+,66-,67-,68+,69-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060775
(CHEMBL413752 | [L-Ala10]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](C)C(N)=O Show InChI InChI=1S/C80H102ClN15O14/c1-46(2)37-63(72(102)89-62(18-11-12-35-84-47(3)4)80(110)96-36-14-19-70(96)79(109)85-48(5)71(82)101)90-74(104)66(40-53-23-30-60(31-24-53)86-49(6)98)92-76(106)67(41-54-25-32-61(33-26-54)87-50(7)99)94-78(108)69(45-97)95-77(107)68(43-56-15-13-34-83-44-56)93-75(105)65(39-52-21-28-59(81)29-22-52)91-73(103)64(88-51(8)100)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,84,97H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,82,101)(H,85,109)(H,86,98)(H,87,99)(H,88,100)(H,89,102)(H,90,104)(H,91,103)(H,92,106)(H,93,105)(H,94,108)(H,95,107)/t48-,62-,63-,64+,65+,66+,67-,68+,69-,70+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060778
(CHEMBL407681 | [D/LAgl (Me, 4-(acetylamino)benzoyl...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1ccc(NC(C)=O)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-75(107)66(41-53-24-31-60(32-25-53)87-49(6)100)94-79(111)71(97(9)80(112)57-27-33-61(34-28-57)88-50(7)101)96-77(109)68(45-99)95-76(108)67(43-55-16-14-35-84-44-55)93-74(106)65(40-52-22-29-59(82)30-23-52)92-73(105)64(89-51(8)102)42-54-21-26-56-17-10-11-18-58(56)39-54/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,107)(H,92,105)(H,93,106)(H,94,111)(H,95,108)(H,96,109)/t48-,62+,63+,64-,65-,66-,67-,68+,69-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060794
(CHEMBL2370593 | [D/LAgl10]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](N)C(N)=O Show InChI InChI=1S/C79H101ClN16O14/c1-45(2)36-61(71(102)88-60(17-10-11-34-84-46(3)4)79(110)96-35-13-18-68(96)78(109)95-69(81)70(82)101)89-73(104)64(39-51-22-29-58(30-23-51)85-47(5)98)91-75(106)65(40-52-24-31-59(32-25-52)86-48(6)99)93-77(108)67(44-97)94-76(107)66(42-54-14-12-33-83-43-54)92-74(105)63(38-50-20-27-57(80)28-21-50)90-72(103)62(87-49(7)100)41-53-19-26-55-15-8-9-16-56(55)37-53/h8-9,12,14-16,19-33,37,43,45-46,60-69,84,97H,10-11,13,17-18,34-36,38-42,44,81H2,1-7H3,(H2,82,101)(H,85,98)(H,86,99)(H,87,100)(H,88,102)(H,89,104)(H,90,103)(H,91,106)(H,92,105)(H,93,108)(H,94,107)(H,95,109)/t60-,61-,62+,63+,64+,65-,66+,67-,68+,69-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060795
(CHEMBL2370590 | [D or LAgl (Me, isopropyl--Ala)8]a...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](N(C)C(=O)CCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)36-61(77(109)95-71(96(9)69(102)32-34-84-46(3)4)80(112)97-35-13-17-68(97)79(111)85-47(5)70(82)103)89-73(105)64(39-52-21-28-59(29-22-52)86-48(6)99)91-75(107)65(40-53-23-30-60(31-24-53)87-49(7)100)93-78(110)67(44-98)94-76(108)66(42-55-14-12-33-83-43-55)92-74(106)63(38-51-19-26-58(81)27-20-51)90-72(104)62(88-50(8)101)41-54-18-25-56-15-10-11-16-57(56)37-54/h10-12,14-16,18-31,33,37,43,45-47,61-68,71,84,98H,13,17,32,34-36,38-42,44H2,1-9H3,(H2,82,103)(H,85,111)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,104)(H,91,107)(H,92,106)(H,93,110)(H,94,108)(H,95,109)/t47-,61+,62-,63-,64-,65+,66-,67+,68-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060806
(CHEMBL263358 | [D/LAgl (4-(acetylamino)benzoyl)5]a...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1ccc(NC(C)=O)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)37-62(72(104)89-61(18-11-12-35-84-46(3)4)80(112)97-36-14-19-68(97)78(110)85-47(5)69(82)102)90-75(107)65(40-52-23-30-59(31-24-52)86-48(6)99)93-79(111)70(95-71(103)56-26-32-60(33-27-56)87-49(7)100)96-77(109)67(44-98)94-76(108)66(42-54-15-13-34-83-43-54)92-74(106)64(39-51-21-28-58(81)29-22-51)91-73(105)63(88-50(8)101)41-53-20-25-55-16-9-10-17-57(55)38-53/h9-10,13,15-17,20-34,38,43,45-47,61-68,70,84,98H,11-12,14,18-19,35-37,39-42,44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,107)(H,91,105)(H,92,106)(H,93,111)(H,94,108)(H,95,103)(H,96,109)/t47-,61+,62+,63-,64-,65-,66-,67+,68-,70+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060791
(CHEMBL2370592 | [D/LAgl (Me/isobutyryl)7]acyline)Show SMILES CC(C)CC(=O)N(C)[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C82H105ClN16O15/c1-47(2)38-71(104)98(9)73(81(113)91-63(19-12-13-36-86-48(3)4)82(114)99-37-15-20-70(99)80(112)87-49(5)72(84)105)97-78(110)67(42-55-26-33-62(34-27-55)89-51(7)102)93-76(108)66(41-54-24-31-61(32-25-54)88-50(6)101)95-79(111)69(46-100)96-77(109)68(44-57-16-14-35-85-45-57)94-75(107)65(40-53-22-29-60(83)30-23-53)92-74(106)64(90-52(8)103)43-56-21-28-58-17-10-11-18-59(58)39-56/h10-11,14,16-18,21-35,39,45,47-49,63-70,73,86,100H,12-13,15,19-20,36-38,40-44,46H2,1-9H3,(H2,84,105)(H,87,112)(H,88,101)(H,89,102)(H,90,103)(H,91,113)(H,92,106)(H,93,108)(H,94,107)(H,95,111)(H,96,109)(H,97,110)/t49-,63+,64-,65-,66+,67-,68-,69+,70-,73+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060792
(CHEMBL407615 | [D or LAgl (formyl)10]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](NC=O)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-46(2)36-62(72(104)89-61(17-10-11-34-84-47(3)4)80(112)97-35-13-18-69(97)79(111)96-71(70(82)103)85-45-99)90-74(106)65(39-52-22-29-59(30-23-52)86-48(5)100)92-76(108)66(40-53-24-31-60(32-25-53)87-49(6)101)94-78(110)68(44-98)95-77(109)67(42-55-14-12-33-83-43-55)93-75(107)64(38-51-20-27-58(81)28-21-51)91-73(105)63(88-50(7)102)41-54-19-26-56-15-8-9-16-57(56)37-54/h8-9,12,14-16,19-33,37,43,45-47,61-69,71,84,98H,10-11,13,17-18,34-36,38-42,44H2,1-7H3,(H2,82,103)(H,85,99)(H,86,100)(H,87,101)(H,88,102)(H,89,104)(H,90,106)(H,91,105)(H,92,108)(H,93,107)(H,94,110)(H,95,109)(H,96,111)/t61-,62-,63+,64+,65+,66-,67+,68-,69+,71-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060809
(CHEMBL267642 | [L or DAgl (formyl)10]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](NC=O)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-46(2)36-62(72(104)89-61(17-10-11-34-84-47(3)4)80(112)97-35-13-18-69(97)79(111)96-71(70(82)103)85-45-99)90-74(106)65(39-52-22-29-59(30-23-52)86-48(5)100)92-76(108)66(40-53-24-31-60(32-25-53)87-49(6)101)94-78(110)68(44-98)95-77(109)67(42-55-14-12-33-83-43-55)93-75(107)64(38-51-20-27-58(81)28-21-51)91-73(105)63(88-50(7)102)41-54-19-26-56-15-8-9-16-57(56)37-54/h8-9,12,14-16,19-33,37,43,45-47,61-69,71,84,98H,10-11,13,17-18,34-36,38-42,44H2,1-7H3,(H2,82,103)(H,85,99)(H,86,100)(H,87,101)(H,88,102)(H,89,104)(H,90,106)(H,91,105)(H,92,108)(H,93,107)(H,94,110)(H,95,109)(H,96,111)/t61-,62-,63+,64+,65+,66-,67+,68-,69+,71+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060773
(CHEMBL262842 | [L or DAgl (nicotinoyl)3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cccnc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)37-62(72(104)89-61(18-11-12-35-84-46(3)4)80(112)97-36-14-19-68(97)78(110)85-47(5)69(82)102)90-74(106)64(40-52-23-30-59(31-24-52)86-48(6)99)91-75(107)65(41-53-25-32-60(33-26-53)87-49(7)100)93-77(109)67(44-98)94-79(111)70(95-71(103)57-17-13-34-83-43-57)96-76(108)66(39-51-21-28-58(81)29-22-51)92-73(105)63(88-50(8)101)42-54-20-27-55-15-9-10-16-56(55)38-54/h9-10,13,15-17,20-34,38,43,45-47,61-68,70,84,98H,11-12,14,18-19,35-37,39-42,44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,106)(H,91,107)(H,92,105)(H,93,109)(H,94,111)(H,95,103)(H,96,108)/t47-,61+,62+,63-,64-,65+,66-,67+,68-,70+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060770
(CHEMBL407058 | [D or LAgl (formyl)4]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@@H](NC=O)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O14/c1-46(2)37-63(72(103)90-62(18-11-12-35-84-47(3)4)80(111)97-36-14-19-69(97)78(109)86-48(5)70(82)102)91-74(105)66(40-53-23-30-60(31-24-53)87-49(6)99)93-76(107)67(41-54-25-32-61(33-26-54)88-50(7)100)95-79(110)71(85-45-98)96-77(108)68(43-56-15-13-34-83-44-56)94-75(106)65(39-52-21-28-59(81)29-22-52)92-73(104)64(89-51(8)101)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44-48,62-69,71,84H,11-12,14,18-19,35-37,39-43H2,1-8H3,(H2,82,102)(H,85,98)(H,86,109)(H,87,99)(H,88,100)(H,89,101)(H,90,103)(H,91,105)(H,92,104)(H,93,107)(H,94,106)(H,95,110)(H,96,108)/t48-,62+,63+,64-,65-,66-,67+,68-,69-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060802
(CHEMBL414558 | [Ac-L-2Nal1]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H102ClN15O14/c1-46(2)37-63(72(102)89-62(18-11-12-35-84-47(3)4)80(110)96-36-14-19-70(96)79(109)85-48(5)71(82)101)90-74(104)66(40-53-23-30-60(31-24-53)86-49(6)98)92-76(106)67(41-54-25-32-61(33-26-54)87-50(7)99)94-78(108)69(45-97)95-77(107)68(43-56-15-13-34-83-44-56)93-75(105)65(39-52-21-28-59(81)29-22-52)91-73(103)64(88-51(8)100)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,84,97H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,82,101)(H,85,109)(H,86,98)(H,87,99)(H,88,100)(H,89,102)(H,90,104)(H,91,103)(H,92,106)(H,93,105)(H,94,108)(H,95,107)/t48-,62+,63+,64+,65-,66-,67+,68-,69+,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060774
(CHEMBL2370594 | [D/LAgl (Me,formyl)10]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](N(C)C=O)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-47(2)37-63(73(105)89-62(18-11-12-35-85-48(3)4)81(113)98-36-14-19-70(98)80(112)96-72(71(83)104)97(8)46-100)90-75(107)66(40-53-23-30-60(31-24-53)86-49(5)101)92-77(109)67(41-54-25-32-61(33-26-54)87-50(6)102)94-79(111)69(45-99)95-78(110)68(43-56-15-13-34-84-44-56)93-76(108)65(39-52-21-28-59(82)29-22-52)91-74(106)64(88-51(7)103)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,72,85,99H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,83,104)(H,86,101)(H,87,102)(H,88,103)(H,89,105)(H,90,107)(H,91,106)(H,92,109)(H,93,108)(H,94,111)(H,95,110)(H,96,112)/t62-,63-,64+,65+,66+,67-,68+,69-,70+,72-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060787
(CHEMBL414469 | [D/LAgl (guanidinoacetyl)8]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)NC(NC(=O)CNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C76H93ClN18O15/c1-41(2)31-56(72(107)94-66(93-64(100)39-82-76(79)80)75(110)95-30-10-14-63(95)74(109)83-42(3)65(78)101)87-68(103)59(34-47-18-25-54(26-19-47)84-43(4)97)89-70(105)60(35-48-20-27-55(28-21-48)85-44(5)98)91-73(108)62(40-96)92-71(106)61(37-50-11-9-29-81-38-50)90-69(104)58(33-46-16-23-53(77)24-17-46)88-67(102)57(86-45(6)99)36-49-15-22-51-12-7-8-13-52(51)32-49/h7-9,11-13,15-29,32,38,41-42,56-63,66,96H,10,14,30-31,33-37,39-40H2,1-6H3,(H2,78,101)(H,83,109)(H,84,97)(H,85,98)(H,86,99)(H,87,103)(H,88,102)(H,89,105)(H,90,104)(H,91,108)(H,92,106)(H,93,100)(H,94,107)(H4,79,80,82)/t42-,56+,57-,58-,59-,60+,61-,62+,63-,66?/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060801
(CHEMBL414468 | [D or LAgl (nicotinoyl)3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cccnc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)37-62(72(104)89-61(18-11-12-35-84-46(3)4)80(112)97-36-14-19-68(97)78(110)85-47(5)69(82)102)90-74(106)64(40-52-23-30-59(31-24-52)86-48(6)99)91-75(107)65(41-53-25-32-60(33-26-53)87-49(7)100)93-77(109)67(44-98)94-79(111)70(95-71(103)57-17-13-34-83-43-57)96-76(108)66(39-51-21-28-58(81)29-22-51)92-73(105)63(88-50(8)101)42-54-20-27-55-15-9-10-16-56(55)38-54/h9-10,13,15-17,20-34,38,43,45-47,61-68,70,84,98H,11-12,14,18-19,35-37,39-42,44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,106)(H,91,107)(H,92,105)(H,93,109)(H,94,111)(H,95,103)(H,96,108)/t47-,61+,62+,63-,64-,65+,66-,67+,68-,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060805
(CHEMBL410798 | [L or LAgl (formyl)4]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](NC=O)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O14/c1-46(2)37-63(72(103)90-62(18-11-12-35-84-47(3)4)80(111)97-36-14-19-69(97)78(109)86-48(5)70(82)102)91-74(105)66(40-53-23-30-60(31-24-53)87-49(6)99)93-76(107)67(41-54-25-32-61(33-26-54)88-50(7)100)95-79(110)71(85-45-98)96-77(108)68(43-56-15-13-34-83-44-56)94-75(106)65(39-52-21-28-59(81)29-22-52)92-73(104)64(89-51(8)101)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44-48,62-69,71,84H,11-12,14,18-19,35-37,39-43H2,1-8H3,(H2,82,102)(H,85,98)(H,86,109)(H,87,99)(H,88,100)(H,89,101)(H,90,103)(H,91,105)(H,92,104)(H,93,107)(H,94,106)(H,95,110)(H,96,108)/t48-,62+,63+,64-,65-,66-,67+,68-,69-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060808
(CHEMBL436683 | [Ac-L or DAgl (2-naphthoyl)1]acylin...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](NC(C)=O)NC(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)37-62(72(104)89-61(18-11-12-35-84-46(3)4)80(112)97-36-14-19-68(97)78(110)85-47(5)69(82)102)90-73(105)63(39-52-22-30-59(31-23-52)86-48(6)99)91-74(106)64(40-53-24-32-60(33-25-53)87-49(7)100)93-77(109)67(44-98)95-76(108)66(41-54-15-13-34-83-43-54)92-75(107)65(38-51-20-28-58(81)29-21-51)94-79(111)70(88-50(8)101)96-71(103)57-27-26-55-16-9-10-17-56(55)42-57/h9-10,13,15-17,20-34,42-43,45-47,61-68,70,84,98H,11-12,14,18-19,35-41,44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,105)(H,91,106)(H,92,107)(H,93,109)(H,94,111)(H,95,108)(H,96,103)/t47-,61+,62+,63-,64+,65-,66-,67+,68-,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.880 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060789
(CHEMBL262309 | [D or LAgl (Me,formyl)4]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O14/c1-47(2)38-64(73(104)90-63(19-12-13-36-85-48(3)4)81(112)98-37-15-20-70(98)79(110)86-49(5)71(83)103)91-75(106)67(41-54-24-31-61(32-25-54)87-50(6)100)93-77(108)68(42-55-26-33-62(34-27-55)88-51(7)101)95-80(111)72(97(9)46-99)96-78(109)69(44-57-16-14-35-84-45-57)94-76(107)66(40-53-22-29-60(82)30-23-53)92-74(105)65(89-52(8)102)43-56-21-28-58-17-10-11-18-59(58)39-56/h10-11,14,16-18,21-35,39,45-49,63-70,72,85H,12-13,15,19-20,36-38,40-44H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,106)(H,92,105)(H,93,108)(H,94,107)(H,95,111)(H,96,109)/t49-,63+,64+,65-,66-,67-,68+,69-,70-,72-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060799
(CHEMBL2370589 | [D/LAgl (Me)10]acyline)Show SMILES CN[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCNC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O Show InChI InChI=1S/C80H103ClN16O14/c1-46(2)37-62(72(103)89-61(18-11-12-35-85-47(3)4)80(111)97-36-14-19-69(97)79(110)96-71(83-8)70(82)102)90-74(105)65(40-52-23-30-59(31-24-52)86-48(5)99)92-76(107)66(41-53-25-32-60(33-26-53)87-49(6)100)94-78(109)68(45-98)95-77(108)67(43-55-15-13-34-84-44-55)93-75(106)64(39-51-21-28-58(81)29-22-51)91-73(104)63(88-50(7)101)42-54-20-27-56-16-9-10-17-57(56)38-54/h9-10,13,15-17,20-34,38,44,46-47,61-69,71,83,85,98H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,82,102)(H,86,99)(H,87,100)(H,88,101)(H,89,103)(H,90,105)(H,91,104)(H,92,107)(H,93,106)(H,94,109)(H,95,108)(H,96,110)/t61-,62-,63+,64+,65+,66-,67+,68-,69+,71-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060777
(CHEMBL429902 | [L or DAgl (Me,4-Cl-benzoyl)2]acyli...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1ccc(Cl)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-73(105)65(40-52-22-31-60(32-23-52)87-49(6)100)92-74(106)66(41-53-24-33-61(34-25-53)88-50(7)101)93-77(109)68(45-99)95-75(107)67(43-55-16-14-35-84-44-55)94-79(111)71(97(9)80(112)57-27-29-59(82)30-28-57)96-76(108)64(89-51(8)102)42-54-21-26-56-17-10-11-18-58(56)39-54/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,109)(H,94,111)(H,95,107)(H,96,108)/t48-,62+,63+,64-,65-,66+,67-,68+,69-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060803
(CHEMBL436897 | [L or DAgl (isonicotinoyl)3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1ccncc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)38-62(72(104)89-61(16-11-12-34-84-46(3)4)80(112)97-37-13-17-68(97)78(110)85-47(5)69(82)102)90-74(106)64(41-52-21-28-59(29-22-52)86-48(6)99)91-75(107)65(42-53-23-30-60(31-24-53)87-49(7)100)93-77(109)67(44-98)94-79(111)70(95-71(103)56-32-35-83-36-33-56)96-76(108)66(40-51-19-26-58(81)27-20-51)92-73(105)63(88-50(8)101)43-54-18-25-55-14-9-10-15-57(55)39-54/h9-10,14-15,18-33,35-36,39,45-47,61-68,70,84,98H,11-13,16-17,34,37-38,40-44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,106)(H,91,107)(H,92,105)(H,93,109)(H,94,111)(H,95,103)(H,96,108)/t47-,61+,62+,63-,64-,65+,66-,67+,68-,70+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060800
(CHEMBL405736 | [D/LAgl (Me,Ac)7]acyline)Show SMILES CC(C)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(C)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C79H99ClN16O15/c1-45(2)83-35-12-11-18-61(79(111)96-36-14-19-68(96)77(109)84-46(3)69(81)102)88-78(110)70(95(8)50(7)101)94-75(107)65(40-53-25-32-60(33-26-53)86-48(5)99)90-73(105)64(39-52-23-30-59(31-24-52)85-47(4)98)92-76(108)67(44-97)93-74(106)66(42-55-15-13-34-82-43-55)91-72(104)63(38-51-21-28-58(80)29-22-51)89-71(103)62(87-49(6)100)41-54-20-27-56-16-9-10-17-57(56)37-54/h9-10,13,15-17,20-34,37,43,45-46,61-68,70,83,97H,11-12,14,18-19,35-36,38-42,44H2,1-8H3,(H2,81,102)(H,84,109)(H,85,98)(H,86,99)(H,87,100)(H,88,110)(H,89,103)(H,90,105)(H,91,104)(H,92,108)(H,93,106)(H,94,107)/t46-,61+,62-,63-,64+,65-,66-,67+,68-,70+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060797
(CHEMBL410818 | [L or DAgl (Me, 4-(acetylamino)benz...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1ccc(NC(C)=O)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)94-79(111)71(97(9)80(112)57-27-33-61(34-28-57)88-50(7)101)96-76(108)66(41-53-24-31-60(32-25-53)87-49(6)100)93-77(109)68(45-99)95-75(107)67(43-55-16-14-35-84-44-55)92-74(106)65(40-52-22-29-59(82)30-23-52)91-73(105)64(89-51(8)102)42-54-21-26-56-17-10-11-18-58(56)39-54/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,109)(H,94,111)(H,95,107)(H,96,108)/t48-,62+,63+,64-,65-,66+,67-,68+,69-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060804
(CHEMBL269097 | [D/LAgl (isobutyryl)7]acyline)Show SMILES CC(C)CC(=O)N[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)37-70(103)96-72(80(112)90-62(18-11-12-35-85-47(3)4)81(113)98-36-14-19-69(98)79(111)86-48(5)71(83)104)97-77(109)66(41-54-25-32-61(33-26-54)88-50(7)101)92-75(107)65(40-53-23-30-60(31-24-53)87-49(6)100)94-78(110)68(45-99)95-76(108)67(43-56-15-13-34-84-44-56)93-74(106)64(39-52-21-28-59(82)29-22-52)91-73(105)63(89-51(8)102)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-69,72,85,99H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,83,104)(H,86,111)(H,87,100)(H,88,101)(H,89,102)(H,90,112)(H,91,105)(H,92,107)(H,93,106)(H,94,110)(H,95,108)(H,96,103)(H,97,109)/t48-,62+,63-,64-,65+,66-,67-,68+,69-,72-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060793
(CHEMBL410799 | [Dpr (isobutyryl)7]acyline)Show SMILES CC(C)CC(=O)N[C@@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)37-70(103)96-72(80(112)90-62(18-11-12-35-85-47(3)4)81(113)98-36-14-19-69(98)79(111)86-48(5)71(83)104)97-77(109)66(41-54-25-32-61(33-26-54)88-50(7)101)92-75(107)65(40-53-23-30-60(31-24-53)87-49(6)100)94-78(110)68(45-99)95-76(108)67(43-56-15-13-34-84-44-56)93-74(106)64(39-52-21-28-59(82)29-22-52)91-73(105)63(89-51(8)102)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-69,72,85,99H,11-12,14,18-19,35-37,39-43,45H2,1-8H3,(H2,83,104)(H,86,111)(H,87,100)(H,88,101)(H,89,102)(H,90,112)(H,91,105)(H,92,107)(H,93,106)(H,94,110)(H,95,108)(H,96,103)(H,97,109)/t48-,62+,63-,64-,65+,66-,67-,68+,69-,72+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060782
(CHEMBL411144 | [L or DAgl (Me, isopropyl--Ala)8]ac...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@H](N(C)C(=O)CCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)36-61(77(109)95-71(96(9)69(102)32-34-84-46(3)4)80(112)97-35-13-17-68(97)79(111)85-47(5)70(82)103)89-73(105)64(39-52-21-28-59(29-22-52)86-48(6)99)91-75(107)65(40-53-23-30-60(31-24-53)87-49(7)100)93-78(110)67(44-98)94-76(108)66(42-55-14-12-33-83-43-55)92-74(106)63(38-51-19-26-58(81)27-20-51)90-72(104)62(88-50(8)101)41-54-18-25-56-15-10-11-16-57(56)37-54/h10-12,14-16,18-31,33,37,43,45-47,61-68,71,84,98H,13,17,32,34-36,38-42,44H2,1-9H3,(H2,82,103)(H,85,111)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,104)(H,91,107)(H,92,106)(H,93,110)(H,94,108)(H,95,109)/t47-,61+,62-,63-,64-,65+,66-,67+,68-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060796
(CHEMBL413456 | [Ac-D or LAgl (2-naphthoyl)1]acylin...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](NC(C)=O)NC(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)37-62(72(104)89-61(18-11-12-35-84-46(3)4)80(112)97-36-14-19-68(97)78(110)85-47(5)69(82)102)90-73(105)63(39-52-22-30-59(31-23-52)86-48(6)99)91-74(106)64(40-53-24-32-60(33-25-53)87-49(7)100)93-77(109)67(44-98)95-76(108)66(41-54-15-13-34-83-43-54)92-75(107)65(38-51-20-28-58(81)29-21-51)94-79(111)70(88-50(8)101)96-71(103)57-27-26-55-16-9-10-17-56(55)42-57/h9-10,13,15-17,20-34,42-43,45-47,61-68,70,84,98H,11-12,14,18-19,35-41,44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,105)(H,91,106)(H,92,107)(H,93,109)(H,94,111)(H,95,108)(H,96,103)/t47-,61+,62+,63-,64+,65-,66-,67+,68-,70+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060790
(CHEMBL444903 | D/LAgl (Ac)7]acyline)Show SMILES CC(C)NCCCC[C@H](NC(=O)[C@H](NC(C)=O)NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C78H97ClN16O15/c1-44(2)82-34-11-10-17-60(78(110)95-35-13-18-67(95)76(108)83-45(3)68(80)101)88-77(109)69(87-49(7)100)94-74(106)64(39-52-24-31-59(32-25-52)85-47(5)98)90-72(104)63(38-51-22-29-58(30-23-51)84-46(4)97)92-75(107)66(43-96)93-73(105)65(41-54-14-12-33-81-42-54)91-71(103)62(37-50-20-27-57(79)28-21-50)89-70(102)61(86-48(6)99)40-53-19-26-55-15-8-9-16-56(55)36-53/h8-9,12,14-16,19-33,36,42,44-45,60-67,69,82,96H,10-11,13,17-18,34-35,37-41,43H2,1-7H3,(H2,80,101)(H,83,108)(H,84,97)(H,85,98)(H,86,99)(H,87,100)(H,88,109)(H,89,102)(H,90,104)(H,91,103)(H,92,107)(H,93,105)(H,94,106)/t45-,60+,61-,62-,63+,64-,65-,66+,67-,69-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060810
(CHEMBL408335 | [D or LAgl (Me, 4-(acetylamino)benz...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1ccc(NC(C)=O)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)94-79(111)71(97(9)80(112)57-27-33-61(34-28-57)88-50(7)101)96-76(108)66(41-53-24-31-60(32-25-53)87-49(6)100)93-77(109)68(45-99)95-75(107)67(43-55-16-14-35-84-44-55)92-74(106)65(40-52-22-29-59(82)30-23-52)91-73(105)64(89-51(8)102)42-54-21-26-56-17-10-11-18-58(56)39-54/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,109)(H,94,111)(H,95,107)(H,96,108)/t48-,62+,63+,64-,65-,66+,67-,68+,69-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060781
(CHEMBL263629 | [L or DAgl (Me,formyl)4]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C=O)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O14/c1-47(2)38-64(73(104)90-63(19-12-13-36-85-48(3)4)81(112)98-37-15-20-70(98)79(110)86-49(5)71(83)103)91-75(106)67(41-54-24-31-61(32-25-54)87-50(6)100)93-77(108)68(42-55-26-33-62(34-27-55)88-51(7)101)95-80(111)72(97(9)46-99)96-78(109)69(44-57-16-14-35-84-45-57)94-76(107)66(40-53-22-29-60(82)30-23-53)92-74(105)65(89-52(8)102)43-56-21-28-58-17-10-11-18-59(58)39-56/h10-11,14,16-18,21-35,39,45-49,63-70,72,85H,12-13,15,19-20,36-38,40-44H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,106)(H,92,105)(H,93,108)(H,94,107)(H,95,111)(H,96,109)/t49-,63+,64+,65-,66-,67-,68+,69-,70-,72+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060784
(CHEMBL265727 | [Ac-L or DAgl (Me,2-naphthoyl)1]acy...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](NC(C)=O)N(C)C(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-73(105)64(40-53-23-31-60(32-24-53)87-49(6)100)92-74(106)65(41-54-25-33-61(34-26-54)88-50(7)101)94-77(109)68(45-99)96-76(108)67(42-55-16-14-35-84-44-55)93-75(107)66(39-52-21-29-59(82)30-22-52)95-79(111)71(89-51(8)102)97(9)80(112)58-28-27-56-17-10-11-18-57(56)43-58/h10-11,14,16-18,21-35,43-44,46-48,62-69,71,85,99H,12-13,15,19-20,36-42,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,107)(H,94,109)(H,95,111)(H,96,108)/t48-,62+,63+,64-,65+,66-,67-,68+,69-,71-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060771
(CHEMBL407193 | [D or LAgl (Me,nicotinoyl)3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1cccnc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-74(106)65(41-53-24-31-60(32-25-53)87-49(6)100)92-75(107)66(42-54-26-33-61(34-27-54)88-50(7)101)94-77(109)68(45-99)95-79(111)71(97(9)80(112)58-18-14-35-84-44-58)96-76(108)67(40-52-22-29-59(82)30-23-52)93-73(105)64(89-51(8)102)43-55-21-28-56-16-10-11-17-57(56)39-55/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,106)(H,92,107)(H,93,105)(H,94,109)(H,95,111)(H,96,108)/t48-,62+,63+,64-,65-,66+,67-,68+,69-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060798
(CHEMBL439258 | [D or LAgl (isonicotinoyl)3]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1ccncc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C80H101ClN16O15/c1-45(2)38-62(72(104)89-61(16-11-12-34-84-46(3)4)80(112)97-37-13-17-68(97)78(110)85-47(5)69(82)102)90-74(106)64(41-52-21-28-59(29-22-52)86-48(6)99)91-75(107)65(42-53-23-30-60(31-24-53)87-49(7)100)93-77(109)67(44-98)94-79(111)70(95-71(103)56-32-35-83-36-33-56)96-76(108)66(40-51-19-26-58(81)27-20-51)92-73(105)63(88-50(8)101)43-54-18-25-55-14-9-10-15-57(55)39-54/h9-10,14-15,18-33,35-36,39,45-47,61-68,70,84,98H,11-13,16-17,34,37-38,40-44H2,1-8H3,(H2,82,102)(H,85,110)(H,86,99)(H,87,100)(H,88,101)(H,89,104)(H,90,106)(H,91,107)(H,92,105)(H,93,109)(H,94,111)(H,95,103)(H,96,108)/t47-,61+,62+,63-,64-,65+,66-,67+,68-,70-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50291968
(CHEMBL216112 | [D or LAgl (Me,4-Cl-benzoyl)2]acyli...)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)N(C)C(=O)c1ccc(Cl)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C81H103ClN16O15/c1-46(2)38-63(72(104)90-62(19-12-13-36-85-47(3)4)81(113)98-37-15-20-69(98)78(110)86-48(5)70(83)103)91-73(105)65(40-52-22-31-60(32-23-52)87-49(6)100)92-74(106)66(41-53-24-33-61(34-25-53)88-50(7)101)93-77(109)68(45-99)95-75(107)67(43-55-16-14-35-84-44-55)94-79(111)71(97(9)80(112)57-27-29-59(82)30-28-57)96-76(108)64(89-51(8)102)42-54-21-26-56-17-10-11-18-58(56)39-54/h10-11,14,16-18,21-35,39,44,46-48,62-69,71,85,99H,12-13,15,19-20,36-38,40-43,45H2,1-9H3,(H2,83,103)(H,86,110)(H,87,100)(H,88,101)(H,89,102)(H,90,104)(H,91,105)(H,92,106)(H,93,109)(H,94,111)(H,95,107)(H,96,108)/t48-,62+,63+,64-,65-,66+,67-,68+,69-,71+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060780
(CHEMBL406211 | [L or DAgl (Apc)2]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cn[nH]c1N)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C77H101N19O15/c1-42(2)33-58(69(103)87-57(18-11-12-31-81-43(3)4)77(111)96-32-14-19-64(96)75(109)83-44(5)66(79)101)88-70(104)60(35-48-21-26-54(27-22-48)84-45(6)98)89-71(105)61(36-49-23-28-55(29-24-49)85-46(7)99)90-74(108)63(41-97)92-72(106)62(38-51-15-13-30-80-39-51)91-76(110)67(93-68(102)56-40-82-95-65(56)78)94-73(107)59(86-47(8)100)37-50-20-25-52-16-9-10-17-53(52)34-50/h9-10,13,15-17,20-30,34,39-40,42-44,57-64,67,81,97H,11-12,14,18-19,31-33,35-38,41H2,1-8H3,(H2,79,101)(H,83,109)(H,84,98)(H,85,99)(H,86,100)(H,87,103)(H,88,104)(H,89,105)(H,90,108)(H,91,110)(H,92,106)(H,93,102)(H,94,107)(H3,78,82,95)/t44-,57+,58+,59-,60-,61+,62-,63+,64-,67+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060788
(CHEMBL429381 | [D or LAgl (Pca)2]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cnccn1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C78H100N18O15/c1-44(2)35-59(69(102)88-58(18-11-12-31-82-45(3)4)78(111)96-34-14-19-66(96)76(109)84-46(5)67(79)101)89-70(103)61(37-50-21-26-56(27-22-50)85-47(6)98)90-71(104)62(38-51-23-28-57(29-24-51)86-48(7)99)91-75(108)65(43-97)93-72(105)63(40-53-15-13-30-80-41-53)92-77(110)68(95-74(107)64-42-81-32-33-83-64)94-73(106)60(87-49(8)100)39-52-20-25-54-16-9-10-17-55(54)36-52/h9-10,13,15-17,20-30,32-33,36,41-42,44-46,58-63,65-66,68,82,97H,11-12,14,18-19,31,34-35,37-40,43H2,1-8H3,(H2,79,101)(H,84,109)(H,85,98)(H,86,99)(H,87,100)(H,88,102)(H,89,103)(H,90,104)(H,91,108)(H,92,110)(H,93,105)(H,94,106)(H,95,107)/t46-,58+,59+,60-,61-,62+,63-,65+,66-,68+/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060772
(CHEMBL384385 | [L or DAgl (Pca)2]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cnccn1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C78H100N18O15/c1-44(2)35-59(69(102)88-58(18-11-12-31-82-45(3)4)78(111)96-34-14-19-66(96)76(109)84-46(5)67(79)101)89-70(103)61(37-50-21-26-56(27-22-50)85-47(6)98)90-71(104)62(38-51-23-28-57(29-24-51)86-48(7)99)91-75(108)65(43-97)93-72(105)63(40-53-15-13-30-80-41-53)92-77(110)68(95-74(107)64-42-81-32-33-83-64)94-73(106)60(87-49(8)100)39-52-20-25-54-16-9-10-17-55(54)36-52/h9-10,13,15-17,20-30,32-33,36,41-42,44-46,58-63,65-66,68,82,97H,11-12,14,18-19,31,34-35,37-40,43H2,1-8H3,(H2,79,101)(H,84,109)(H,85,98)(H,86,99)(H,87,100)(H,88,102)(H,89,103)(H,90,104)(H,91,108)(H,92,110)(H,93,105)(H,94,106)(H,95,107)/t46-,58+,59+,60-,61-,62+,63-,65+,66-,68-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50060783
(CHEMBL263200 | [D or LAgL (Apc)2]acyline)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)NC(=O)c1cn[nH]c1N)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C77H101N19O15/c1-42(2)33-58(69(103)87-57(18-11-12-31-81-43(3)4)77(111)96-32-14-19-64(96)75(109)83-44(5)66(79)101)88-70(104)60(35-48-21-26-54(27-22-48)84-45(6)98)89-71(105)61(36-49-23-28-55(29-24-49)85-46(7)99)90-74(108)63(41-97)92-72(106)62(38-51-15-13-30-80-39-51)91-76(110)67(93-68(102)56-40-82-95-65(56)78)94-73(107)59(86-47(8)100)37-50-20-25-52-16-9-10-17-53(52)34-50/h9-10,13,15-17,20-30,34,39-40,42-44,57-64,67,81,97H,11-12,14,18-19,31-33,35-38,41H2,1-8H3,(H2,79,101)(H,83,109)(H,84,98)(H,85,99)(H,86,100)(H,87,103)(H,88,104)(H,89,105)(H,90,108)(H,91,110)(H,92,106)(H,93,102)(H,94,107)(H3,78,82,95)/t44-,57+,58+,59-,60-,61+,62-,63+,64-,67-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute
Curated by ChEMBL
| Assay Description
Inhibition of binding of radiolabeled histrelin to Gonadotropin-releasing hormone receptor (GnRHr) in rat pituitary gland membranes |
J Med Chem 40: 3739-48 (1997)
Article DOI: 10.1021/jm970024p
BindingDB Entry DOI: 10.7270/Q24J0D8X |
More data for this
Ligand-Target Pair | |
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