Found 110 hits Enz. Inhib. hit(s) with all data for entry = 50044473 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM25771
(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)Show InChI InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50419652
(MILVETEROL)Show SMILES O[C@@H](CNCCc1ccc(NC[C@H](O)c2ccccc2)cc1)c1ccc(O)c(NC=O)c1 |r| Show InChI InChI=1S/C25H29N3O4/c29-17-28-22-14-20(8-11-23(22)30)24(31)15-26-13-12-18-6-9-21(10-7-18)27-16-25(32)19-4-2-1-3-5-19/h1-11,14,17,24-27,30-32H,12-13,15-16H2,(H,28,29)/t24-,25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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KEGG PC cid PC sid UniChem
| Article PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM86453
(CAS_73573-87-2 | Formoterol | NSC_3083544)Show InChI InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| DrugBank Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018608
(CHEMBL3290989)Show SMILES COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1-c1ccccc1 Show InChI InChI=1S/C30H32N2O4/c1-36-30-14-12-26(18-27(30)22-5-3-2-4-6-22)32-25-10-7-21(8-11-25)15-16-31-19-29(35)23-9-13-28(34)24(17-23)20-33/h2-14,17-18,29,31-35H,15-16,19-20H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018557
(CHEMBL3290992)Show SMILES CSc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C24H28N2O3S/c1-30-22-9-7-21(8-10-22)26-20-5-2-17(3-6-20)12-13-25-15-24(29)18-4-11-23(28)19(14-18)16-27/h2-11,14,24-29H,12-13,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018558
(CHEMBL3290993)Show SMILES CC(C)Oc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C26H32N2O4/c1-18(2)32-24-10-8-23(9-11-24)28-22-6-3-19(4-7-22)13-14-27-16-26(31)20-5-12-25(30)21(15-20)17-29/h3-12,15,18,26-31H,13-14,16-17H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018563
(CHEMBL3290991)Show SMILES CCOc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C25H30N2O4/c1-2-31-23-10-8-22(9-11-23)27-21-6-3-18(4-7-21)13-14-26-16-25(30)19-5-12-24(29)20(15-19)17-28/h3-12,15,25-30H,2,13-14,16-17H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018562
(CHEMBL3290996)Show SMILES COC(=O)c1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C25H28N2O5/c1-32-25(31)18-4-9-22(10-5-18)27-21-7-2-17(3-8-21)12-13-26-15-24(30)19-6-11-23(29)20(14-19)16-28/h2-11,14,24,26-30H,12-13,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018606
(CHEMBL3290987)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H30N2O3/c32-20-25-18-24(10-15-28(25)33)29(34)19-30-17-16-21-6-11-26(12-7-21)31-27-13-8-23(9-14-27)22-4-2-1-3-5-22/h1-15,18,29-34H,16-17,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018602
(CHEMBL3290983)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C27H28N2O3/c30-18-23-15-22(8-12-26(23)31)27(32)17-28-14-13-19-5-9-24(10-6-19)29-25-11-7-20-3-1-2-4-21(20)16-25/h1-12,15-16,27-32H,13-14,17-18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018601
(CHEMBL3290982)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C29H30N2O4/c32-20-23-18-22(8-15-28(23)33)29(34)19-30-17-16-21-6-9-24(10-7-21)31-25-11-13-27(14-12-25)35-26-4-2-1-3-5-26/h1-15,18,29-34H,16-17,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018607
(CHEMBL3290988)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H30N2O3/c32-20-25-17-24(11-14-28(25)33)29(34)19-30-16-15-21-9-12-26(13-10-21)31-27-8-4-7-23(18-27)22-5-2-1-3-6-22/h1-14,17-18,29-34H,15-16,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018609
(CHEMBL3290990)Show SMILES COc1cccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)c1 Show InChI InChI=1S/C24H28N2O4/c1-30-22-4-2-3-21(14-22)26-20-8-5-17(6-9-20)11-12-25-15-24(29)18-7-10-23(28)19(13-18)16-27/h2-10,13-14,24-29H,11-12,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018605
(CHEMBL3290986)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc3CCCc3c2)cc1 Show InChI InChI=1S/C26H30N2O3/c29-17-22-14-21(7-11-25(22)30)26(31)16-27-13-12-18-4-8-23(9-5-18)28-24-10-6-19-2-1-3-20(19)15-24/h4-11,14-15,26-31H,1-3,12-13,16-17H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018603
(CHEMBL3290984)Show SMILES COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C24H28N2O4/c1-30-22-9-7-21(8-10-22)26-20-5-2-17(3-6-20)12-13-25-15-24(29)18-4-11-23(28)19(14-18)16-27/h2-11,14,24-29H,12-13,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018561
(CHEMBL3290995)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H25FN2O3/c24-19-4-8-21(9-5-19)26-20-6-1-16(2-7-20)11-12-25-14-23(29)17-3-10-22(28)18(13-17)15-27/h1-10,13,23,25-29H,11-12,14-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018559
(CHEMBL3290994)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(O)cc2)cc1 Show InChI InChI=1S/C23H26N2O4/c26-15-18-13-17(3-10-22(18)28)23(29)14-24-12-11-16-1-4-19(5-2-16)25-20-6-8-21(27)9-7-20/h1-10,13,23-29H,11-12,14-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM86453
(CAS_73573-87-2 | Formoterol | NSC_3083544)Show InChI InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM25771
(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)Show InChI InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018604
(CHEMBL3290985)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C27H28N2O3/c30-18-22-16-21(10-13-26(22)31)27(32)17-28-15-14-19-8-11-23(12-9-19)29-25-7-3-5-20-4-1-2-6-24(20)25/h1-13,16,27-32H,14-15,17-18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018601
(CHEMBL3290982)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C29H30N2O4/c32-20-23-18-22(8-15-28(23)33)29(34)19-30-17-16-21-6-9-24(10-7-21)31-25-11-13-27(14-12-25)35-26-4-2-1-3-5-26/h1-15,18,29-34H,16-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018561
(CHEMBL3290995)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H25FN2O3/c24-19-4-8-21(9-5-19)26-20-6-1-16(2-7-20)11-12-25-14-23(29)17-3-10-22(28)18(13-17)15-27/h1-10,13,23,25-29H,11-12,14-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018557
(CHEMBL3290992)Show SMILES CSc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C24H28N2O3S/c1-30-22-9-7-21(8-10-22)26-20-5-2-17(3-6-20)12-13-25-15-24(29)18-4-11-23(28)19(14-18)16-27/h2-11,14,24-29H,12-13,15-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018592
(CHEMBL3290973)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(NCc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C28H30N2O3/c31-19-25-16-24(9-12-27(25)32)28(33)18-29-14-13-20-6-10-26(11-7-20)30-17-21-5-8-22-3-1-2-4-23(22)15-21/h1-12,15-16,28-33H,13-14,17-19H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018591
(CHEMBL3290972)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(NCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C24H26Cl2N2O3/c25-21-7-3-17(11-22(21)26)13-28-20-5-1-16(2-6-20)9-10-27-14-24(31)18-4-8-23(30)19(12-18)15-29/h1-8,11-12,24,27-31H,9-10,13-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018599
(CHEMBL3290980)Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCNCC(O)c2ccc(O)c(CO)c2)cc1 Show InChI InChI=1S/C23H31N3O4/c1-17(28)25-10-12-26(13-11-25)21-5-2-18(3-6-21)8-9-24-15-23(30)19-4-7-22(29)20(14-19)16-27/h2-7,14,23-24,27,29-30H,8-13,15-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018600
(CHEMBL3290981)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCC(CC1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C30H37N3O4/c34-21-25-19-24(8-11-28(25)35)29(36)20-31-15-12-22-6-9-27(10-7-22)33-16-13-26(14-17-33)32-30(37)18-23-4-2-1-3-5-23/h1-11,19,26,29,31,34-36H,12-18,20-21H2,(H,32,37) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018598
(CHEMBL3290979)Show SMILES COc1ccc(CN2CCN(CC2)c2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C29H37N3O4/c1-36-27-9-4-23(5-10-27)20-31-14-16-32(17-15-31)26-7-2-22(3-8-26)12-13-30-19-29(35)24-6-11-28(34)25(18-24)21-33/h2-11,18,29-30,33-35H,12-17,19-21H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018562
(CHEMBL3290996)Show SMILES COC(=O)c1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C25H28N2O5/c1-32-25(31)18-4-9-22(10-5-18)27-21-7-2-17(3-8-21)12-13-26-15-24(30)19-6-11-23(29)20(14-19)16-28/h2-11,14,24,26-30H,12-13,15-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50419652
(MILVETEROL)Show SMILES O[C@@H](CNCCc1ccc(NC[C@H](O)c2ccccc2)cc1)c1ccc(O)c(NC=O)c1 |r| Show InChI InChI=1S/C25H29N3O4/c29-17-28-22-14-20(8-11-23(22)30)24(31)15-26-13-12-18-6-9-21(10-7-18)27-16-25(32)19-4-2-1-3-5-19/h1-11,14,17,24-27,30-32H,12-13,15-16H2,(H,28,29)/t24-,25-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
KEGG PC cid PC sid UniChem
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018590
(CHEMBL3290971)Show InChI InChI=1S/C17H20BrNO3/c18-15-4-1-12(2-5-15)7-8-19-10-17(22)13-3-6-16(21)14(9-13)11-20/h1-6,9,17,19-22H,7-8,10-11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018591
(CHEMBL3290972)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(NCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C24H26Cl2N2O3/c25-21-7-3-17(11-22(21)26)13-28-20-5-1-16(2-6-20)9-10-27-14-24(31)18-4-8-23(30)19(12-18)15-29/h1-8,11-12,24,27-31H,9-10,13-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018592
(CHEMBL3290973)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(NCc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C28H30N2O3/c31-19-25-16-24(9-12-27(25)32)28(33)18-29-14-13-20-6-10-26(11-7-20)30-17-21-5-8-22-3-1-2-4-23(22)15-21/h1-12,15-16,28-33H,13-14,17-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018593
(CHEMBL3290974)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C28H34N2O3/c31-20-25-18-24(8-11-27(25)32)28(33)19-29-15-12-21-6-9-26(10-7-21)30-16-13-23(14-17-30)22-4-2-1-3-5-22/h1-11,18,23,28-29,31-33H,12-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018597
(CHEMBL3290978)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C27H33N3O3/c31-20-23-18-22(8-11-26(23)32)27(33)19-28-13-12-21-6-9-25(10-7-21)30-16-14-29(15-17-30)24-4-2-1-3-5-24/h1-11,18,27-28,31-33H,12-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018600
(CHEMBL3290981)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCC(CC1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C30H37N3O4/c34-21-25-19-24(8-11-28(25)35)29(36)20-31-15-12-22-6-9-27(10-7-22)33-16-13-26(14-17-33)32-30(37)18-23-4-2-1-3-5-23/h1-11,19,26,29,31,34-36H,12-18,20-21H2,(H,32,37) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018599
(CHEMBL3290980)Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCNCC(O)c2ccc(O)c(CO)c2)cc1 Show InChI InChI=1S/C23H31N3O4/c1-17(28)25-10-12-26(13-11-25)21-5-2-18(3-6-21)8-9-24-15-23(30)19-4-7-22(29)20(14-19)16-27/h2-7,14,23-24,27,29-30H,8-13,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018598
(CHEMBL3290979)Show SMILES COc1ccc(CN2CCN(CC2)c2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C29H37N3O4/c1-36-27-9-4-23(5-10-27)20-31-14-16-32(17-15-31)26-7-2-22(3-8-26)12-13-30-19-29(35)24-6-11-28(34)25(18-24)21-33/h2-11,18,29-30,33-35H,12-17,19-21H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018602
(CHEMBL3290983)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C27H28N2O3/c30-18-23-15-22(8-12-26(23)31)27(32)17-28-14-13-19-5-9-24(10-6-19)29-25-11-7-20-3-1-2-4-21(20)16-25/h1-12,15-16,27-32H,13-14,17-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018593
(CHEMBL3290974)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C28H34N2O3/c31-20-25-18-24(8-11-27(25)32)28(33)19-29-15-12-21-6-9-26(10-7-21)30-16-13-23(14-17-30)22-4-2-1-3-5-22/h1-11,18,23,28-29,31-33H,12-17,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018607
(CHEMBL3290988)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H30N2O3/c32-20-25-17-24(11-14-28(25)33)29(34)19-30-16-15-21-9-12-26(13-10-21)31-27-8-4-7-23(18-27)22-5-2-1-3-6-22/h1-14,17-18,29-34H,15-16,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018606
(CHEMBL3290987)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H30N2O3/c32-20-25-18-24(10-15-28(25)33)29(34)19-30-17-16-21-6-11-26(12-7-21)31-27-13-8-23(9-14-27)22-4-2-1-3-5-22/h1-15,18,29-34H,16-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018609
(CHEMBL3290990)Show SMILES COc1cccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)c1 Show InChI InChI=1S/C24H28N2O4/c1-30-22-4-2-3-21(14-22)26-20-8-5-17(6-9-20)11-12-25-15-24(29)18-7-10-23(28)19(13-18)16-27/h2-10,13-14,24-29H,11-12,15-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018594
(CHEMBL3290975)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C29H36N2O3/c32-21-26-19-25(8-11-28(26)33)29(34)20-30-15-12-22-6-9-27(10-7-22)31-16-13-24(14-17-31)18-23-4-2-1-3-5-23/h1-11,19,24,29-30,32-34H,12-18,20-21H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018558
(CHEMBL3290993)Show SMILES CC(C)Oc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C26H32N2O4/c1-18(2)32-24-10-8-23(9-11-24)28-22-6-3-19(4-7-22)13-14-27-16-26(31)20-5-12-25(30)21(15-20)17-29/h3-12,15,18,26-31H,13-14,16-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018608
(CHEMBL3290989)Show SMILES COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1-c1ccccc1 Show InChI InChI=1S/C30H32N2O4/c1-36-30-14-12-26(18-27(30)22-5-3-2-4-6-22)32-25-10-7-21(8-11-25)15-16-31-19-29(35)23-9-13-28(34)24(17-23)20-33/h2-14,17-18,29,31-35H,15-16,19-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018605
(CHEMBL3290986)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(Nc2ccc3CCCc3c2)cc1 Show InChI InChI=1S/C26H30N2O3/c29-17-22-14-21(7-11-25(22)30)26(31)16-27-13-12-18-4-8-23(9-5-18)28-24-10-6-19-2-1-3-20(19)15-24/h4-11,14-15,26-31H,1-3,12-13,16-17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018590
(CHEMBL3290971)Show InChI InChI=1S/C17H20BrNO3/c18-15-4-1-12(2-5-15)7-8-19-10-17(22)13-3-6-16(21)14(9-13)11-20/h1-6,9,17,19-22H,7-8,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018597
(CHEMBL3290978)Show SMILES OCc1cc(ccc1O)C(O)CNCCc1ccc(cc1)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C27H33N3O3/c31-20-23-18-22(8-11-26(23)32)27(33)19-28-13-12-21-6-9-25(10-7-21)30-16-14-29(15-17-30)24-4-2-1-3-5-24/h1-11,18,27-28,31-33H,12-17,19-20H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta2 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50018603
(CHEMBL3290984)Show SMILES COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 Show InChI InChI=1S/C24H28N2O4/c1-30-22-9-7-21(8-10-22)26-20-5-2-17(3-6-20)12-13-25-15-24(29)18-4-11-23(28)19(14-18)16-27/h2-11,14,24-29H,12-13,15-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from beta1 receptor (unknown origin) by liquid scintillation counting and cell based assay |
Bioorg Med Chem Lett 24: 2625-30 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.069 BindingDB Entry DOI: 10.7270/Q2M32X96 |
More data for this Ligand-Target Pair | |