Compile Data Set for Download or QSAR

Found 66 hits Enz. Inhib. hit(s) with all data for entry = 50044541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020165 (CHEMBL3288526 | US9914707, I-4) Show SMILES Nc1ncnc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C23H16N4OS/c24-21-20-19(12-29-23(20)26-13-25-21)15-9-10-17-14(11-15)5-4-8-18(17)22(28)27-16-6-2-1-3-7-16/h1-13H,(H,27,28)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020166 (CHEMBL3288505 | US9914707, I-8) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)cc1 Show InChI InChI=1S/C25H20N4O/c1-15-8-11-18(12-9-15)27-25(30)21-6-2-4-16-14-17(10-13-19(16)21)20-5-3-7-22-23(20)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020167 (CHEMBL3288518 | US9914707, I-17) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cc(Cl)cc(Cl)c3)c12 Show InChI InChI=1S/C24H16Cl2N4O/c25-15-10-16(26)12-17(11-15)28-24(31)20-5-1-3-13-9-14(7-8-18(13)20)19-4-2-6-21-22(19)23(27)30-29-21/h1-12H,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020169 (CHEMBL3288506 | US9914707, I-9) Show SMILES CCc1cccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C26H22N4O/c1-2-16-6-3-8-19(14-16)28-26(31)22-10-4-7-17-15-18(12-13-20(17)22)21-9-5-11-23-24(21)25(27)30-29-23/h3-15H,2H2,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020165 (CHEMBL3288526 | US9914707, I-4) Show SMILES Nc1ncnc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C23H16N4OS/c24-21-20-19(12-29-23(20)26-13-25-21)15-9-10-17-14(11-15)5-4-8-18(17)22(28)27-16-6-2-1-3-7-16/h1-13H,(H,27,28)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020170 (CHEMBL3288502 | US9914707, I-1) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H18N4O/c25-23-22-19(9-5-11-21(22)27-28-23)16-12-13-18-15(14-16)6-4-10-20(18)24(29)26-17-7-2-1-3-8-17/h1-14H,(H,26,29)(H3,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020193 (CHEMBL3288515 | US9914707, I-14) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cc(F)cc(F)c3)c12 Show InChI InChI=1S/C24H16F2N4O/c25-15-10-16(26)12-17(11-15)28-24(31)20-5-1-3-13-9-14(7-8-18(13)20)19-4-2-6-21-22(19)23(27)30-29-21/h1-12H,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020166 (CHEMBL3288505 | US9914707, I-8) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)cc1 Show InChI InChI=1S/C25H20N4O/c1-15-8-11-18(12-9-15)27-25(30)21-6-2-4-16-14-17(10-13-19(16)21)20-5-3-7-22-23(20)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020194 (CHEMBL3288504 | US9914707, I-7) Show SMILES Cc1cccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C25H20N4O/c1-15-5-2-7-18(13-15)27-25(30)21-9-3-6-16-14-17(11-12-19(16)21)20-8-4-10-22-23(20)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020195 (CHEMBL3288512 | US9914707, I-11) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(F)c3)c12 Show InChI InChI=1S/C24H17FN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21079 (1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020210 (CHEMBL3288519 | US9914707, I-18) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cc(Br)cc(Br)c3)c12 Show InChI InChI=1S/C24H16Br2N4O/c25-15-10-16(26)12-17(11-15)28-24(31)20-5-1-3-13-9-14(7-8-18(13)20)19-4-2-6-21-22(19)23(27)30-29-21/h1-12H,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020223 (CHEMBL3288514 | US9914707, I-13) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccc(F)cc3F)c12 Show InChI InChI=1S/C24H16F2N4O/c25-15-8-10-20(19(26)12-15)28-24(31)18-5-1-3-13-11-14(7-9-16(13)18)17-4-2-6-21-22(17)23(27)30-29-21/h1-12H,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020225 (CHEMBL3288523 | US9914707, I-27) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)NC3CC3)c12 Show InChI InChI=1S/C21H18N4O/c22-20-19-16(4-2-6-18(19)24-25-20)13-7-10-15-12(11-13)3-1-5-17(15)21(26)23-14-8-9-14/h1-7,10-11,14H,8-9H2,(H,23,26)(H3,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020227 (CHEMBL3288516 | US9914707, I-15) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(Cl)c3)c12 Show InChI InChI=1S/C24H17ClN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020228 (CHEMBL3288509 | US9914707, I-22) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c(F)c1 Show InChI InChI=1S/C25H19FN4O/c1-14-8-11-21(20(26)12-14)28-25(31)19-6-2-4-15-13-16(9-10-17(15)19)18-5-3-7-22-23(18)24(27)30-29-22/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020229 (CHEMBL3288508 | US9914707, I-20) Show SMILES Cc1ccc(F)c(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C25H19FN4O/c1-14-8-11-20(26)22(12-14)28-25(31)19-6-2-4-15-13-16(9-10-17(15)19)18-5-3-7-21-23(18)24(27)30-29-21/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020170 (CHEMBL3288502 | US9914707, I-1) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H18N4O/c25-23-22-19(9-5-11-21(22)27-28-23)16-12-13-18-15(14-16)6-4-10-20(18)24(29)26-17-7-2-1-3-8-17/h1-14H,(H,26,29)(H3,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020230 (CHEMBL3288517 | US9914707, I-16) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(Br)c3)c12 Show InChI InChI=1S/C24H17BrN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020233 (CHEMBL3288510 | US9914707, I-23) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)cc1F Show InChI InChI=1S/C25H19FN4O/c1-14-8-10-17(13-21(14)26)28-25(31)20-6-2-4-15-12-16(9-11-18(15)20)19-5-3-7-22-23(19)24(27)30-29-22/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020233 (CHEMBL3288510 | US9914707, I-23) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)cc1F Show InChI InChI=1S/C25H19FN4O/c1-14-8-10-17(13-21(14)26)28-25(31)20-6-2-4-15-12-16(9-11-18(15)20)19-5-3-7-22-23(19)24(27)30-29-22/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50020165 (CHEMBL3288526 | US9914707, I-4) Show SMILES Nc1ncnc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C23H16N4OS/c24-21-20-19(12-29-23(20)26-13-25-21)15-9-10-17-14(11-15)5-4-8-18(17)22(28)27-16-6-2-1-3-7-16/h1-13H,(H,27,28)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant PDGFR-beta (unknown origin) using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020234 (CHEMBL3288520 | US9914707, I-24) Show SMILES Cc1cc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)no1 Show InChI InChI=1S/C22H17N5O2/c1-12-10-19(27-29-12)24-22(28)17-6-2-4-13-11-14(8-9-15(13)17)16-5-3-7-18-20(16)21(23)26-25-18/h2-11H,1H3,(H3,23,25,26)(H,24,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020229 (CHEMBL3288508 | US9914707, I-20) Show SMILES Cc1ccc(F)c(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C25H19FN4O/c1-14-8-11-20(26)22(12-14)28-25(31)19-6-2-4-15-13-16(9-10-17(15)19)18-5-3-7-21-23(18)24(27)30-29-21/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020235 (CHEMBL3288511 | US9914707, I-10) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3F)c12 Show InChI InChI=1S/C24H17FN4O/c25-19-8-1-2-9-20(19)27-24(30)18-7-3-5-14-13-15(11-12-16(14)18)17-6-4-10-21-22(17)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21079 (1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020236 (CHEMBL3288524 | US9914707, I-2) Show SMILES Nc1nccc2occ(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H17N3O2/c25-23-22-20(14-29-21(22)11-12-26-23)16-9-10-18-15(13-16)5-4-8-19(18)24(28)27-17-6-2-1-3-7-17/h1-14H,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020238 (CHEMBL3288522 | US9914707, I-26) Show SMILES CCNC(=O)c1cccc2cc(ccc12)-c1cccc2[nH]nc(N)c12 Show InChI InChI=1S/C20H18N4O/c1-2-22-20(25)16-7-3-5-12-11-13(9-10-14(12)16)15-6-4-8-17-18(15)19(21)24-23-17/h3-11H,2H2,1H3,(H,22,25)(H3,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020195 (CHEMBL3288512 | US9914707, I-11) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(F)c3)c12 Show InChI InChI=1S/C24H17FN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020239 (CHEMBL3288525 | US9914707, I-3) Show SMILES Nc1nccc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H17N3OS/c25-23-22-20(14-29-21(22)11-12-26-23)16-9-10-18-15(13-16)5-4-8-19(18)24(28)27-17-6-2-1-3-7-17/h1-14H,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020194 (CHEMBL3288504 | US9914707, I-7) Show SMILES Cc1cccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C25H20N4O/c1-15-5-2-7-18(13-15)27-25(30)21-9-3-6-16-14-17(11-12-19(16)21)20-8-4-10-22-23(20)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020242 (CHEMBL3288507 | US9914707, I-19) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(c3)C(F)(F)F)c12 Show InChI InChI=1S/C25H17F3N4O/c26-25(27,28)16-5-2-6-17(13-16)30-24(33)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(29)32-31-21/h1-13H,(H,30,33)(H3,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020228 (CHEMBL3288509 | US9914707, I-22) Show SMILES Cc1ccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c(F)c1 Show InChI InChI=1S/C25H19FN4O/c1-14-8-11-21(20(26)12-14)28-25(31)19-6-2-4-15-13-16(9-10-17(15)19)18-5-3-7-22-23(18)24(27)30-29-22/h2-13H,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020245 (CHEMBL3288513 | US9914707, I-12) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccc(F)cc3)c12 Show InChI InChI=1S/C24H17FN4O/c25-16-8-10-17(11-9-16)27-24(30)20-5-1-3-14-13-15(7-12-18(14)20)19-4-2-6-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020234 (CHEMBL3288520 | US9914707, I-24) Show SMILES Cc1cc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)no1 Show InChI InChI=1S/C22H17N5O2/c1-12-10-19(27-29-12)24-22(28)17-6-2-4-13-11-14(8-9-15(13)17)16-5-3-7-18-20(16)21(23)26-25-18/h2-11H,1H3,(H3,23,25,26)(H,24,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020193 (CHEMBL3288515 | US9914707, I-14) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cc(F)cc(F)c3)c12 Show InChI InChI=1S/C24H16F2N4O/c25-15-10-16(26)12-17(11-15)28-24(31)20-5-1-3-13-9-14(7-8-18(13)20)19-4-2-6-21-22(19)23(27)30-29-21/h1-12H,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020249 (CHEMBL3288527) Show SMILES Nc1n[nH]c2cccc(-c3ccc4N(CCOc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C22H19N5O2/c23-21-20-16(7-4-8-17(20)25-26-21)14-9-10-18-19(13-14)29-12-11-27(18)22(28)24-15-5-2-1-3-6-15/h1-10,13H,11-12H2,(H,24,28)(H3,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020245 (CHEMBL3288513 | US9914707, I-12) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccc(F)cc3)c12 Show InChI InChI=1S/C24H17FN4O/c25-16-8-10-17(11-9-16)27-24(30)20-5-1-3-14-13-15(7-12-18(14)20)19-4-2-6-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020169 (CHEMBL3288506 | US9914707, I-9) Show SMILES CCc1cccc(NC(=O)c2cccc3cc(ccc23)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C26H22N4O/c1-2-16-6-3-8-19(14-16)28-26(31)22-10-4-7-17-15-18(12-13-20(17)22)21-9-5-11-23-24(21)25(27)30-29-23/h3-15H,2H2,1H3,(H,28,31)(H3,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020235 (CHEMBL3288511 | US9914707, I-10) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3F)c12 Show InChI InChI=1S/C24H17FN4O/c25-19-8-1-2-9-20(19)27-24(30)18-7-3-5-14-13-15(11-12-16(14)18)17-6-4-10-21-22(17)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50020165 (CHEMBL3288526 | US9914707, I-4) Show SMILES Nc1ncnc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C23H16N4OS/c24-21-20-19(12-29-23(20)26-13-25-21)15-9-10-17-14(11-15)5-4-8-18(17)22(28)27-16-6-2-1-3-7-16/h1-13H,(H,27,28)(H2,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant RET (unknown origin) using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020246 (CHEMBL3288521 | US9914707, I-25) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccnc3)c12 Show InChI InChI=1S/C23H17N5O/c24-22-21-18(6-2-8-20(21)27-28-22)15-9-10-17-14(12-15)4-1-7-19(17)23(29)26-16-5-3-11-25-13-16/h1-13H,(H,26,29)(H3,24,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020239 (CHEMBL3288525 | US9914707, I-3) Show SMILES Nc1nccc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H17N3OS/c25-23-22-20(14-29-21(22)11-12-26-23)16-9-10-18-15(13-16)5-4-8-19(18)24(28)27-17-6-2-1-3-7-17/h1-14H,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020236 (CHEMBL3288524 | US9914707, I-2) Show SMILES Nc1nccc2occ(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C24H17N3O2/c25-23-22-20(14-29-21(22)11-12-26-23)16-9-10-18-15(13-16)5-4-8-19(18)24(28)27-17-6-2-1-3-7-17/h1-14H,(H2,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020230 (CHEMBL3288517 | US9914707, I-16) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(Br)c3)c12 Show InChI InChI=1S/C24H17BrN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020248 (CHEMBL3288503 | US9914707, I-6) Show SMILES Cc1ccccc1NC(=O)c1cccc2cc(ccc12)-c1cccc2[nH]nc(N)c12 Show InChI InChI=1S/C25H20N4O/c1-15-6-2-3-10-21(15)27-25(30)20-9-4-7-16-14-17(12-13-18(16)20)19-8-5-11-22-23(19)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50020165 (CHEMBL3288526 | US9914707, I-4) Show SMILES Nc1ncnc2scc(-c3ccc4c(cccc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C23H16N4OS/c24-21-20-19(12-29-23(20)26-13-25-21)15-9-10-17-14(11-15)5-4-8-18(17)22(28)27-16-6-2-1-3-7-16/h1-13H,(H,27,28)(H2,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant VEGFR-1 (unknown origin) using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020249 (CHEMBL3288527) Show SMILES Nc1n[nH]c2cccc(-c3ccc4N(CCOc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C22H19N5O2/c23-21-20-16(7-4-8-17(20)25-26-21)14-9-10-18-19(13-14)29-12-11-27(18)22(28)24-15-5-2-1-3-6-15/h1-10,13H,11-12H2,(H,24,28)(H3,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020227 (CHEMBL3288516 | US9914707, I-15) Show SMILES Nc1n[nH]c2cccc(-c3ccc4c(cccc4c3)C(=O)Nc3cccc(Cl)c3)c12 Show InChI InChI=1S/C24H17ClN4O/c25-16-5-2-6-17(13-16)27-24(30)20-8-1-4-14-12-15(10-11-18(14)20)19-7-3-9-21-22(19)23(26)29-28-21/h1-13H,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020248 (CHEMBL3288503 | US9914707, I-6) Show SMILES Cc1ccccc1NC(=O)c1cccc2cc(ccc12)-c1cccc2[nH]nc(N)c12 Show InChI InChI=1S/C25H20N4O/c1-15-6-2-3-10-21(15)27-25(30)20-9-4-7-16-14-17(12-13-18(16)20)19-8-5-11-22-23(19)24(26)29-28-22/h2-14H,1H3,(H,27,30)(H3,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair

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