Compile Data Set for Download or QSAR

Found 66 hits Enz. Inhib. hit(s) with all data for entry = 50012889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123880 ((4-Chloro-phenyl)-(2-chloro-pyridine-4-carbonyl)-t...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccnc(Cl)c1 Show InChI InChI=1S/C23H15Cl2N3O4S/c24-15-5-7-16(8-6-15)28(20(29)14-9-10-26-19(25)13-14)23(33)32-12-11-27-21(30)17-3-1-2-4-18(17)22(27)31/h1-10,13H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptase				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123871 ((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccco1 Show InChI InChI=1S/C22H15ClN2O5S/c23-14-7-9-15(10-8-14)25(21(28)18-6-3-12-29-18)22(31)30-13-11-24-19(26)16-4-1-2-5-17(16)20(24)27/h1-10,12H,11,13H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptase				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123875 ((4-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15ClN2O4S2/c23-14-7-9-15(10-8-14)25(21(28)18-6-3-13-31-18)22(30)29-12-11-24-19(26)16-4-1-2-5-17(16)20(24)27/h1-10,13H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptase				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM1866 (3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...) Show SMILES Brc1ccc(NC(=S)NCCc2ccccn2)nc1 Show InChI InChI=1S/C13H13BrN4S/c14-10-4-5-12(17-9-10)18-13(19)16-8-6-11-3-1-2-7-15-11/h1-5,7,9H,6,8H2,(H2,16,17,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptase				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 Show InChI InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Activity of selected HIV-1 N-acylthiocarbamates in enzyme assay against Virion-Associated reverse transcriptase				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123872 ((2-Phenoxy-acetyl)-phenyl-thiocarbamic acid O-(1-m...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)COc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H23NO4S/c1-19(17-27-21-13-7-3-8-14-21)29-24(30)25(20-11-5-2-6-12-20)23(26)18-28-22-15-9-4-10-16-22/h2-16,19H,17-18H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123870 (Benzoyl-phenyl-thiocarbamic acid O-[2-(1,3-dioxo-1...) Show SMILES O=C(N(C(=S)OCCN1C(=O)c2ccccc2C1=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H18N2O4S/c27-21(17-9-3-1-4-10-17)26(18-11-5-2-6-12-18)24(31)30-16-15-25-22(28)19-13-7-8-14-20(19)23(25)29/h1-14H,15-16H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123917 ((4-Fluoro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES Fc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15FN2O4S2/c23-14-7-9-15(10-8-14)25(21(28)18-6-3-13-31-18)22(30)29-12-11-24-19(26)16-4-1-2-5-17(16)20(24)27/h1-10,13H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123881 ((4-Ethyl-phenyl)-(furan-2-carbonyl)-thiocarbamic a...) Show SMILES CCc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccco1 Show InChI InChI=1S/C24H20N2O5S/c1-2-16-9-11-17(12-10-16)26(23(29)20-8-5-14-30-20)24(32)31-15-13-25-21(27)18-6-3-4-7-19(18)22(25)28/h3-12,14H,2,13,15H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123890 (CHEMBL166333 | O-(1-methyl-2-phenoxyethyl) O-pheny...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)Oc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H21NO4S/c1-18(17-26-20-13-7-3-8-14-20)27-23(29)24(19-11-5-2-6-12-19)22(25)28-21-15-9-4-10-16-21/h2-16,18H,17H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123895 (Benzoyl-phenyl-thiocarbamic acid O-phenethyl ester...) Show SMILES O=C(N(C(=S)OCCc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H19NO2S/c24-21(19-12-6-2-7-13-19)23(20-14-8-3-9-15-20)22(26)25-17-16-18-10-4-1-5-11-18/h1-15H,16-17H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123916 (CHEMBL349827 | Phenyl-(thiophene-2-carbonyl)-thioc...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1ccccc1 Show InChI InChI=1S/C21H19NO3S2/c1-16(15-24-18-11-6-3-7-12-18)25-21(26)22(17-9-4-2-5-10-17)20(23)19-13-8-14-27-19/h2-14,16H,15H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123900 ((Naphthalene-2-carbonyl)-phenyl-thiocarbamic acid ...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1ccc2ccccc2c1)c1ccccc1 Show InChI InChI=1S/C27H23NO3S/c1-20(19-30-25-14-6-3-7-15-25)31-27(32)28(24-12-4-2-5-13-24)26(29)23-17-16-21-10-8-9-11-22(21)18-23/h2-18,20H,19H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123921 ((3-Nitro-benzoyl)-phenyl-thiocarbamic acid O-(1-me...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1cccc(c1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C23H20N2O5S/c1-17(16-29-21-13-6-3-7-14-21)30-23(31)24(19-10-4-2-5-11-19)22(26)18-9-8-12-20(15-18)25(27)28/h2-15,17H,16H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123886 ((Thiophene-2-carbonyl)-(3-trifluoromethyl-phenyl)-...) Show SMILES FC(F)(F)c1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C23H15F3N2O4S2/c24-23(25,26)14-5-3-6-15(13-14)28(21(31)18-9-4-12-34-18)22(33)32-11-10-27-19(29)16-7-1-2-8-17(16)20(27)30/h1-9,12-13H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123888 ((2-Ethyl-phenyl)-(thiophene-2-carbonyl)-thiocarbam...) Show SMILES CCc1ccccc1N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C24H20N2O4S2/c1-2-16-8-3-6-11-19(16)26(23(29)20-12-7-15-32-20)24(31)30-14-13-25-21(27)17-9-4-5-10-18(17)22(25)28/h3-12,15H,2,13-14H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123906 ((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES Clc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15ClN2O4S2/c23-14-5-3-6-15(13-14)25(21(28)18-9-4-12-31-18)22(30)29-11-10-24-19(26)16-7-1-2-8-17(16)20(24)27/h1-9,12-13H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123877 (Benzoyl-phenyl-thiocarbamic acid O-furan-2-ylmethy...) Show SMILES O=C(N(C(=S)OCc1ccco1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H15NO3S/c21-18(15-8-3-1-4-9-15)20(16-10-5-2-6-11-16)19(24)23-14-17-12-7-13-22-17/h1-13H,14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.83E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123868 ((4-Methyl-benzoyl)-phenyl-thiocarbamic acid O-(2-p...) Show SMILES Cc1ccc(cc1)C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H21NO3S/c1-18-12-14-19(15-13-18)22(25)24(20-8-4-2-5-9-20)23(28)27-17-16-26-21-10-6-3-7-11-21/h2-15H,16-17H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123924 ((3-Acetyl-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES CC(=O)c1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C24H18N2O5S2/c1-15(27)16-6-4-7-17(14-16)26(23(30)20-10-5-13-33-20)24(32)31-12-11-25-21(28)18-8-2-3-9-19(18)22(25)29/h2-10,13-14H,11-12H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123909 ((3-Fluoro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES Fc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15FN2O4S2/c23-14-5-3-6-15(13-14)25(21(28)18-9-4-12-31-18)22(30)29-11-10-24-19(26)16-7-1-2-8-17(16)20(24)27/h1-9,12-13H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM1866 (3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...) Show SMILES Brc1ccc(NC(=S)NCCc2ccccn2)nc1 Show InChI InChI=1S/C13H13BrN4S/c14-10-4-5-12(17-9-10)18-13(19)16-8-6-11-3-1-2-7-15-11/h1-5,7,9H,6,8H2,(H2,16,17,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123883 ((Thiophene-2-carbonyl)-p-tolyl-thiocarbamic acid O...) Show SMILES Cc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C23H18N2O4S2/c1-15-8-10-16(11-9-15)25(22(28)19-7-4-14-31-19)23(30)29-13-12-24-20(26)17-5-2-3-6-18(17)21(24)27/h2-11,14H,12-13H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123889 (CHEMBL164697 | Phenyl-(tetrahydro-furan-2-carbonyl...) Show SMILES O=C(C1CCCO1)N(C(=S)OCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H19NO3S/c21-18(17-12-7-13-22-17)20(16-10-5-2-6-11-16)19(24)23-14-15-8-3-1-4-9-15/h1-6,8-11,17H,7,12-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123905 ((3-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbam...) Show SMILES [O-][N+](=O)c1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15N3O6S2/c26-19-16-7-1-2-8-17(16)20(27)23(19)10-11-31-22(32)24(21(28)18-9-4-12-33-18)14-5-3-6-15(13-14)25(29)30/h1-9,12-13H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123925 ((Thiophene-2-carbonyl)-m-tolyl-thiocarbamic acid O...) Show SMILES Cc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C23H18N2O4S2/c1-15-6-4-7-16(14-15)25(22(28)19-10-5-13-31-19)23(30)29-12-11-24-20(26)17-8-2-3-9-18(17)21(24)27/h2-10,13-14H,11-12H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123914 ((2-Phenoxy-acetyl)-phenyl-thiocarbamic acid O-(2-p...) Show SMILES O=C(COc1ccccc1)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H21NO4S/c25-22(18-28-21-14-8-3-9-15-21)24(19-10-4-1-5-11-19)23(29)27-17-16-26-20-12-6-2-7-13-20/h1-15H,16-18H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123923 (CHEMBL164503 | Phenyl-(3,4,5-trimethoxy-benzoyl)-t...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H25NO6S/c1-28-21-16-18(17-22(29-2)23(21)30-3)24(27)26(19-10-6-4-7-11-19)25(33)32-15-14-31-20-12-8-5-9-13-20/h4-13,16-17H,14-15H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123878 ((4-Chloro-3-nitro-benzoyl)-phenyl-thiocarbamic aci...) Show SMILES [O-][N+](=O)c1cc(ccc1Cl)C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H17ClN2O5S/c23-19-12-11-16(15-20(19)25(27)28)21(26)24(17-7-3-1-4-8-17)22(31)30-14-13-29-18-9-5-2-6-10-18/h1-12,15H,13-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123875 ((4-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15ClN2O4S2/c23-14-7-9-15(10-8-14)25(21(28)18-6-3-13-31-18)22(30)29-12-11-24-19(26)16-4-1-2-5-17(16)20(24)27/h1-10,13H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123892 ((3-Methoxy-phenyl)-(thiophene-2-carbonyl)-thiocarb...) Show SMILES COc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C23H18N2O5S2/c1-29-16-7-4-6-15(14-16)25(22(28)19-10-5-13-32-19)23(31)30-12-11-24-20(26)17-8-2-3-9-18(17)21(24)27/h2-10,13-14H,11-12H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123893 ((3-Bromo-phenyl)-(thiophene-2-carbonyl)-thiocarbam...) Show SMILES Brc1cccc(c1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1cccs1 Show InChI InChI=1S/C22H15BrN2O4S2/c23-14-5-3-6-15(13-14)25(21(28)18-9-4-12-31-18)22(30)29-11-10-24-19(26)16-7-1-2-8-17(16)20(24)27/h1-9,12-13H,10-11H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123918 ((4-Chloro-benzoyl)-phenyl-thiocarbamic acid O-(2-p...) Show SMILES Clc1ccc(cc1)C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H18ClNO3S/c23-18-13-11-17(12-14-18)21(25)24(19-7-3-1-4-8-19)22(28)27-16-15-26-20-9-5-2-6-10-20/h1-14H,15-16H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123896 ((4-Chloro-benzoyl)-(4-chloro-phenyl)-thiocarbamic ...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H16Cl2N2O4S/c25-16-7-5-15(6-8-16)21(29)28(18-11-9-17(26)10-12-18)24(33)32-14-13-27-22(30)19-3-1-2-4-20(19)23(27)31/h1-12H,13-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123904 ((3,5-Dichloro-benzoyl)-phenyl-thiocarbamic acid O-...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H17Cl2NO3S/c23-17-13-16(14-18(24)15-17)21(26)25(19-7-3-1-4-8-19)22(29)28-12-11-27-20-9-5-2-6-10-20/h1-10,13-15H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123867 (Benzoyl-(4-bromo-phenyl)-thiocarbamic acid O-[2-(1...) Show SMILES Brc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccccc1 Show InChI InChI=1S/C24H17BrN2O4S/c25-17-10-12-18(13-11-17)27(21(28)16-6-2-1-3-7-16)24(32)31-15-14-26-22(29)19-8-4-5-9-20(19)23(26)30/h1-13H,14-15H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123879 (Benzoyl-phenyl-thiocarbamic acid O-(2-phenylsulfan...) Show SMILES O=C(N(C(=S)OCCSc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H19NO2S2/c24-21(18-10-4-1-5-11-18)23(19-12-6-2-7-13-19)22(26)25-16-17-27-20-14-8-3-9-15-20/h1-15H,16-17H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>4.40E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123885 (Benzoyl-(4-fluoro-phenyl)-thiocarbamic acid O-(2-p...) Show SMILES Fc1ccc(cc1)N(C(=S)OCCOc1ccccc1)C(=O)c1ccccc1 Show InChI InChI=1S/C22H18FNO3S/c23-18-11-13-19(14-12-18)24(21(25)17-7-3-1-4-8-17)22(28)27-16-15-26-20-9-5-2-6-10-20/h1-14H,15-16H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123912 ((4-Nitro-phenyl)-(thiophene-2-carbonyl)-thiocarbam...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H18N2O5S2/c1-15(14-27-18-6-3-2-4-7-18)28-21(29)22(20(24)19-8-5-13-30-19)16-9-11-17(12-10-16)23(25)26/h2-13,15H,14H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123897 ((3-Chloro-phenyl)-(thiophene-2-carbonyl)-thiocarba...) Show SMILES CC(COc1ccccc1)OC(=S)N(C(=O)c1cccs1)c1cccc(Cl)c1 Show InChI InChI=1S/C21H18ClNO3S2/c1-15(14-25-18-9-3-2-4-10-18)26-21(27)23(17-8-5-7-16(22)13-17)20(24)19-11-6-12-28-19/h2-13,15H,14H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123884 ((Furan-2-carbonyl)-phenyl-thiocarbamic acid O-phen...) Show SMILES O=C(N(C(=S)OCCc1ccccc1)c1ccccc1)c1ccco1 Show InChI InChI=1S/C20H17NO3S/c22-19(18-12-7-14-23-18)21(17-10-5-2-6-11-17)20(25)24-15-13-16-8-3-1-4-9-16/h1-12,14H,13,15H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123894 (CHEMBL165288 | Phenyl-(3-phenyl-acryloyl)-thiocarb...) Show SMILES O=C(\C=C\c1ccccc1)N(C(=S)OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H21NO2S/c26-23(17-16-20-10-4-1-5-11-20)25(22-14-8-3-9-15-22)24(28)27-19-18-21-12-6-2-7-13-21/h1-17H,18-19H2/b17-16+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123898 ((2,4-Dichloro-benzoyl)-phenyl-thiocarbamic acid O-...) Show SMILES Clc1ccc(C(=O)N(C(=S)OCCOc2ccccc2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C22H17Cl2NO3S/c23-16-11-12-19(20(24)15-16)21(26)25(17-7-3-1-4-8-17)22(29)28-14-13-27-18-9-5-2-6-10-18/h1-12,15H,13-14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123901 (CHEMBL351212 | O-butyl O-(1-methyl-2-phenoxyethyl)...) Show SMILES CCCCOC(=O)N(C(=S)OC(C)COc1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H25NO4S/c1-3-4-15-24-20(23)22(18-11-7-5-8-12-18)21(27)26-17(2)16-25-19-13-9-6-10-14-19/h5-14,17H,3-4,15-16H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123880 ((4-Chloro-phenyl)-(2-chloro-pyridine-4-carbonyl)-t...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccnc(Cl)c1 Show InChI InChI=1S/C23H15Cl2N3O4S/c24-15-5-7-16(8-6-15)28(20(29)14-9-10-26-19(25)13-14)23(33)32-12-11-27-21(30)17-3-1-2-4-18(17)22(27)31/h1-10,13H,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123882 (Benzoyl-(4-chloro-phenyl)-thiocarbamic acid O-[2-(...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccccc1 Show InChI InChI=1S/C24H17ClN2O4S/c25-17-10-12-18(13-11-17)27(21(28)16-6-2-1-3-7-16)24(32)31-15-14-26-22(29)19-8-4-5-9-20(19)23(26)30/h1-13H,14-15H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123903 (CHEMBL168044 | O-(1-methyl-2-phenoxyethyl) O-propy...) Show SMILES CCCOC(=O)N(C(=S)OC(C)COc1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H23NO4S/c1-3-14-23-19(22)21(17-10-6-4-7-11-17)20(26)25-16(2)15-24-18-12-8-5-9-13-18/h4-13,16H,3,14-15H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123871 ((4-Chloro-phenyl)-(furan-2-carbonyl)-thiocarbamic ...) Show SMILES Clc1ccc(cc1)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)C(=O)c1ccco1 Show InChI InChI=1S/C22H15ClN2O5S/c23-14-7-9-15(10-8-14)25(21(28)18-6-3-12-29-18)22(31)30-13-11-24-19(26)16-4-1-2-5-17(16)20(24)27/h1-10,12H,11,13H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123911 ((4-Chloro-benzoyl)-phenyl-thiocarbamic acid O-phen...) Show SMILES Clc1ccc(cc1)C(=O)N(C(=S)OCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H18ClNO2S/c23-19-13-11-18(12-14-19)21(25)24(20-9-5-2-6-10-20)22(27)26-16-15-17-7-3-1-4-8-17/h1-14H,15-16H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50123887 (Benzoyl-cyclohexyl-thiocarbamic acid O-(2-phenoxy-...) Show SMILES O=C(N(C1CCCCC1)C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H25NO3S/c24-21(18-10-4-1-5-11-18)23(19-12-6-2-7-13-19)22(27)26-17-16-25-20-14-8-3-9-15-20/h1,3-5,8-11,14-15,19H,2,6-7,12-13,16-17H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 66 total )  |  Next  |  Last  >>

Jump to: