Found 50 hits Enz. Inhib. hit(s) with all data for entry = 50008675 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine protease 1
(Homo sapiens (Human)) | BDBM50063698
(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#6](=O)-[#8]-c1ccc2cc(ccc2c1)-[#6](-[#7])=[#7] Show InChI InChI=1S/C19H17N5O2/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23/h1-10H,(H3,20,21)(H4,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50063745
(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)Show InChI InChI=1S/C15H8F3IN2O2/c16-15(17,18)8-5-6-9-12(7-8)21-14(23-13(9)22)20-11-4-2-1-3-10(11)19/h1-7H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Compound was evaluated in vitro for inhibitory activity against purified human C1r protease protease |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075982
(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C16H14N2O5S/c1-18(24(20,21)12-9-7-11(22-2)8-10-12)16-17-14-6-4-3-5-13(14)15(19)23-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075980
(4-Chloro-N-ethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show SMILES CCN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN2O4S/c1-2-19(24(21,22)12-9-7-11(17)8-10-12)16-18-14-6-4-3-5-13(14)15(20)23-16/h3-10H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075979
(4-Chloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClN2O4S/c1-18(23(20,21)11-8-6-10(16)7-9-11)15-17-13-5-3-2-4-12(13)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075992
(4-Guanidino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxaz...)Show SMILES [#6]-[#7](-c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C16H15N5O4S/c1-21(16-20-13-5-3-2-4-12(13)14(22)25-16)26(23,24)11-8-6-10(7-9-11)19-15(17)18/h2-9H,1H3,(H4,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075986
(CHEMBL168038 | N-Ethyl-N-(4-oxo-4H-benzo[d][1,3]ox...)Show InChI InChI=1S/C16H14N2O4S/c1-2-18(23(20,21)12-8-4-3-5-9-12)16-17-14-11-7-6-10-13(14)15(19)22-16/h3-11H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075981
(4-Amino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H13N3O4S/c1-18(23(20,21)11-8-6-10(16)7-9-11)15-17-13-5-3-2-4-12(13)14(19)22-15/h2-9H,16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075978
(2-Bromo-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H11BrN2O4S/c1-18(23(20,21)13-9-5-3-7-11(13)16)15-17-12-8-4-2-6-10(12)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075992
(4-Guanidino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxaz...)Show SMILES [#6]-[#7](-c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C16H15N5O4S/c1-21(16-20-13-5-3-2-4-12(13)14(22)25-16)26(23,24)11-8-6-10(7-9-11)19-15(17)18/h2-9H,1H3,(H4,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075986
(CHEMBL168038 | N-Ethyl-N-(4-oxo-4H-benzo[d][1,3]ox...)Show InChI InChI=1S/C16H14N2O4S/c1-2-18(23(20,21)12-8-4-3-5-9-12)16-17-14-11-7-6-10-13(14)15(19)22-16/h3-11H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075993
(CHEMBL166632 | N-Methyl-N-(4-oxo-4H-benzo[d][1,3]o...)Show InChI InChI=1S/C15H12N2O4S/c1-17(22(19,20)11-7-3-2-4-8-11)15-16-13-10-6-5-9-12(13)14(18)21-15/h2-10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50063745
(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)Show InChI InChI=1S/C15H8F3IN2O2/c16-15(17,18)8-5-6-9-12(7-8)21-14(23-13(9)22)20-11-4-2-1-3-10(11)19/h1-7H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075991
(3-Chloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H11ClN2O4S/c1-18(23(20,21)11-6-4-5-10(16)9-11)15-17-13-8-3-2-7-12(13)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075989
(CHEMBL167163 | Naphthalene-1-sulfonic acid methyl-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H14N2O4S/c1-21(19-20-16-11-5-4-10-15(16)18(22)25-19)26(23,24)17-12-6-8-13-7-2-3-9-14(13)17/h2-12H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075987
(4,N-Dimethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)...)Show InChI InChI=1S/C16H14N2O4S/c1-11-7-9-12(10-8-11)23(20,21)18(2)16-17-14-6-4-3-5-13(14)15(19)22-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075990
(4-tert-Butyl-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H20N2O4S/c1-19(2,3)13-9-11-14(12-10-13)26(23,24)21(4)18-20-16-8-6-5-7-15(16)17(22)25-18/h5-12H,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075982
(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C16H14N2O5S/c1-18(24(20,21)12-9-7-11(22-2)8-10-12)16-17-14-6-4-3-5-13(14)15(19)23-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075993
(CHEMBL166632 | N-Methyl-N-(4-oxo-4H-benzo[d][1,3]o...)Show InChI InChI=1S/C15H12N2O4S/c1-17(22(19,20)11-7-3-2-4-8-11)15-16-13-10-6-5-9-12(13)14(18)21-15/h2-10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075989
(CHEMBL167163 | Naphthalene-1-sulfonic acid methyl-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H14N2O4S/c1-21(19-20-16-11-5-4-10-15(16)18(22)25-19)26(23,24)17-12-6-8-13-7-2-3-9-14(13)17/h2-12H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075981
(4-Amino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H13N3O4S/c1-18(23(20,21)11-8-6-10(16)7-9-11)15-17-13-5-3-2-4-12(13)14(19)22-15/h2-9H,16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075981
(4-Amino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H13N3O4S/c1-18(23(20,21)11-8-6-10(16)7-9-11)15-17-13-5-3-2-4-12(13)14(19)22-15/h2-9H,16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075984
(2,6-Dichloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H10Cl2N2O4S/c1-19(24(21,22)13-10(16)6-4-7-11(13)17)15-18-12-8-3-2-5-9(12)14(20)23-15/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075987
(4,N-Dimethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)...)Show InChI InChI=1S/C16H14N2O4S/c1-11-7-9-12(10-8-11)23(20,21)18(2)16-17-14-6-4-3-5-13(14)15(19)22-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075985
(3,4-Dichloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H10Cl2N2O4S/c1-19(24(21,22)9-6-7-11(16)12(17)8-9)15-18-13-5-3-2-4-10(13)14(20)23-15/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075986
(CHEMBL168038 | N-Ethyl-N-(4-oxo-4H-benzo[d][1,3]ox...)Show InChI InChI=1S/C16H14N2O4S/c1-2-18(23(20,21)12-8-4-3-5-9-12)16-17-14-11-7-6-10-13(14)15(19)22-16/h3-11H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075989
(CHEMBL167163 | Naphthalene-1-sulfonic acid methyl-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H14N2O4S/c1-21(19-20-16-11-5-4-10-15(16)18(22)25-19)26(23,24)17-12-6-8-13-7-2-3-9-14(13)17/h2-12H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075984
(2,6-Dichloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H10Cl2N2O4S/c1-19(24(21,22)13-10(16)6-4-7-11(13)17)15-18-12-8-3-2-5-9(12)14(20)23-15/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50063698
(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#6](=O)-[#8]-c1ccc2cc(ccc2c1)-[#6](-[#7])=[#7] Show InChI InChI=1S/C19H17N5O2/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23/h1-10H,(H3,20,21)(H4,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50063698
(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#6](=O)-[#8]-c1ccc2cc(ccc2c1)-[#6](-[#7])=[#7] Show InChI InChI=1S/C19H17N5O2/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23/h1-10H,(H3,20,21)(H4,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075977
(4-Cyano-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C16H11N3O4S/c1-19(24(21,22)12-8-6-11(10-17)7-9-12)16-18-14-5-3-2-4-13(14)15(20)23-16/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075991
(3-Chloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H11ClN2O4S/c1-18(23(20,21)11-6-4-5-10(16)9-11)15-17-13-8-3-2-7-12(13)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075978
(2-Bromo-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H11BrN2O4S/c1-18(23(20,21)13-9-5-3-7-11(13)16)15-17-12-8-4-2-6-10(12)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075980
(4-Chloro-N-ethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show SMILES CCN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN2O4S/c1-2-19(24(21,22)12-9-7-11(17)8-10-12)16-18-14-6-4-3-5-13(14)15(20)23-16/h3-10H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075976
(CHEMBL165875 | N-Methyl-4-nitro-N-(4-oxo-4H-benzo[...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O6S/c1-17(15-16-13-5-3-2-4-12(13)14(19)24-15)25(22,23)11-8-6-10(7-9-11)18(20)21/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075991
(3-Chloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H11ClN2O4S/c1-18(23(20,21)11-6-4-5-10(16)9-11)15-17-13-8-3-2-7-12(13)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075990
(4-tert-Butyl-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H20N2O4S/c1-19(2,3)13-9-11-14(12-10-13)26(23,24)21(4)18-20-16-8-6-5-7-15(16)17(22)25-18/h5-12H,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075990
(4-tert-Butyl-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H20N2O4S/c1-19(2,3)13-9-11-14(12-10-13)26(23,24)21(4)18-20-16-8-6-5-7-15(16)17(22)25-18/h5-12H,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075984
(2,6-Dichloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C15H10Cl2N2O4S/c1-19(24(21,22)13-10(16)6-4-7-11(13)17)15-18-12-8-3-2-5-9(12)14(20)23-15/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075979
(4-Chloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H11ClN2O4S/c1-18(23(20,21)11-8-6-10(16)7-9-11)15-17-13-5-3-2-4-12(13)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075980
(4-Chloro-N-ethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show SMILES CCN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN2O4S/c1-2-19(24(21,22)12-9-7-11(17)8-10-12)16-18-14-6-4-3-5-13(14)15(20)23-16/h3-10H,2H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075985
(3,4-Dichloro-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxa...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H10Cl2N2O4S/c1-19(24(21,22)9-6-7-11(16)12(17)8-9)15-18-13-5-3-2-4-10(13)14(20)23-15/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutes |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075988
(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]thiazi...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1nc2ccccc2c(=O)s1 Show InChI InChI=1S/C16H14N2O4S2/c1-18(24(20,21)12-9-7-11(22-2)8-10-12)16-17-14-6-4-3-5-13(14)15(19)23-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Complement C1r subcomponent
(Homo sapiens (Human)) | BDBM50075983
(CHEMBL167467 | N-Methyl-N-(4-oxo-4H-benzo[d][1,3]t...)Show InChI InChI=1S/C15H12N2O3S2/c1-17(22(19,20)11-7-3-2-4-8-11)15-16-13-10-6-5-9-12(13)14(18)21-15/h2-10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human C1r protease. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075982
(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1nc2ccccc2c(=O)o1 Show InChI InChI=1S/C16H14N2O5S/c1-18(24(20,21)12-9-7-11(22-2)8-10-12)16-17-14-6-4-3-5-13(14)15(19)23-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075978
(2-Bromo-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show InChI InChI=1S/C15H11BrN2O4S/c1-18(23(20,21)13-9-5-3-7-11(13)16)15-17-12-8-4-2-6-10(12)14(19)22-15/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075977
(4-Cyano-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C16H11N3O4S/c1-19(24(21,22)12-8-6-11(10-17)7-9-12)16-18-14-5-3-2-4-13(14)15(20)23-16/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50063745
(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)Show InChI InChI=1S/C15H8F3IN2O2/c16-15(17,18)8-5-6-9-12(7-8)21-14(23-13(9)22)20-11-4-2-1-3-10(11)19/h1-7H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075976
(CHEMBL165875 | N-Methyl-4-nitro-N-(4-oxo-4H-benzo[...)Show SMILES CN(c1nc2ccccc2c(=O)o1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O6S/c1-17(15-16-13-5-3-2-4-12(13)14(19)24-15)25(22,23)11-8-6-10(7-9-11)18(20)21/h2-9H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50075988
(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]thiazi...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1nc2ccccc2c(=O)s1 Show InChI InChI=1S/C16H14N2O4S2/c1-18(24(20,21)12-9-7-11(22-2)8-10-12)16-17-14-6-4-3-5-13(14)15(19)23-16/h3-10H,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description In vitro for inhibition of purified bovine trypsin. |
Bioorg Med Chem Lett 9: 815-20 (1999)
BindingDB Entry DOI: 10.7270/Q29G5M0K |
More data for this Ligand-Target Pair | |