Found 22 hits Enz. Inhib. hit(s) with all data for entry = 50017192 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50164047
(CHEMBL361097 | N-[2,2'']Bithiophenyl-5-ylmethyl-N'...)Show SMILES NS(=O)(=O)c1ccccc1-c1ccc(CNC(=O)CCC(=O)NCc2ccc(s2)-c2cccs2)cc1 Show InChI InChI=1S/C26H25N3O4S3/c27-36(32,33)24-6-2-1-4-21(24)19-9-7-18(8-10-19)16-28-25(30)13-14-26(31)29-17-20-11-12-23(35-20)22-5-3-15-34-22/h1-12,15H,13-14,16-17H2,(H,28,30)(H,29,31)(H2,27,32,33) | PDB
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PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178865
(CHEMBL203440 | trans-N-benzyl-2-(1-hydroxy-3-(3-(t...)Show SMILES OC(CCc1cccc(OC(F)(F)F)c1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H26F3NO3/c24-23(25,26)30-18-9-4-8-16(14-18)12-13-21(28)19-10-5-11-20(19)22(29)27-15-17-6-2-1-3-7-17/h1-4,6-9,14,19-21,28H,5,10-13,15H2,(H,27,29)/t19-,20-,21?/m1/s1 | PDB
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PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178861
((1R,2R)-N1-methyl-N1-((2'-sulfamoylbiphenyl-4-yl)m...)Show SMILES CN(Cc1ccc(cc1)-c1ccccc1S(N)(=O)=O)C(=O)[C@@H]1CCC[C@H]1C(=O)NCc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C29H30F3N3O5S/c1-35(18-20-9-13-21(14-10-20)23-5-2-3-8-26(23)41(33,38)39)28(37)25-7-4-6-24(25)27(36)34-17-19-11-15-22(16-12-19)40-29(30,31)32/h2-3,5,8-16,24-25H,4,6-7,17-18H2,1H3,(H,34,36)(H2,33,38,39)/t24-,25-/m1/s1 | PDB
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PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178859
(CHEMBL205258 | trans-N-benzyl-2-(1-hydroxy-3-(2-(t...)Show SMILES OC(CCc1ccccc1OC(F)(F)F)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H26F3NO3/c24-23(25,26)30-21-12-5-4-9-17(21)13-14-20(28)18-10-6-11-19(18)22(29)27-15-16-7-2-1-3-8-16/h1-5,7-9,12,18-20,28H,6,10-11,13-15H2,(H,27,29)/t18-,19-,20?/m1/s1 | PDB
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PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178867
(CHEMBL206431 | N-((trans-2-(1-hydroxy-3-phenylprop...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1CNC(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H26F3NO3/c24-23(25,26)30-19-12-10-17(11-13-19)22(29)27-15-18-7-4-8-20(18)21(28)14-9-16-5-2-1-3-6-16/h1-3,5-6,10-13,18,20-21,28H,4,7-9,14-15H2,(H,27,29)/t18-,20+,21?/m0/s1 | PDB
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| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178863
(CHEMBL203185 | trans-N-benzyl-2-((S)-1-hydroxy-3-(...)Show SMILES OC(CCc1ccc(OC(F)(F)F)cc1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1 Show InChI InChI=1S/C23H26F3NO3/c24-23(25,26)30-18-12-9-16(10-13-18)11-14-21(28)19-7-4-8-20(19)22(29)27-15-17-5-2-1-3-6-17/h1-3,5-6,9-10,12-13,19-21,28H,4,7-8,11,14-15H2,(H,27,29)/t19-,20-,21?/m1/s1 | PDB
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PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178853
(CHEMBL206615 | trans-N-(3,5-dichlorobenzyl)-2-(1-h...)Show SMILES OC(CCc1cccc(OC(F)(F)F)c1)[C@@H]1CCC[C@H]1C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C23H24Cl2F3NO3/c24-16-9-15(10-17(25)12-16)13-29-22(31)20-6-2-5-19(20)21(30)8-7-14-3-1-4-18(11-14)32-23(26,27)28/h1,3-4,9-12,19-21,30H,2,5-8,13H2,(H,29,31)/t19-,20-,21?/m1/s1 | PDB
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| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178854
(CHEMBL202745 | trans-N-(2-(trifluoromethyl)benzyl)...)Show SMILES OC(CCc1cccc(OC(F)(F)F)c1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1C(F)(F)F Show InChI InChI=1S/C24H25F6NO3/c25-23(26,27)20-10-2-1-6-16(20)14-31-22(33)19-9-4-8-18(19)21(32)12-11-15-5-3-7-17(13-15)34-24(28,29)30/h1-3,5-7,10,13,18-19,21,32H,4,8-9,11-12,14H2,(H,31,33)/t18-,19-,21?/m1/s1 | PDB
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| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178864
(CHEMBL204399 | N-((trans-2-(1-hydroxy-3-phenylprop...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1CNS(=O)(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C22H26F3NO4S/c23-22(24,25)30-18-10-12-19(13-11-18)31(28,29)26-15-17-7-4-8-20(17)21(27)14-9-16-5-2-1-3-6-16/h1-3,5-6,10-13,17,20-21,26-27H,4,7-9,14-15H2/t17-,20+,21?/m0/s1 | PDB
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| Article
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| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178851
(1-(trans-2-((4-(trifluoromethoxy)benzyloxy)methyl)...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1COCc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H27F3O3/c24-23(25,26)29-20-12-9-18(10-13-20)15-28-16-19-7-4-8-21(19)22(27)14-11-17-5-2-1-3-6-17/h1-3,5-6,9-10,12-13,19,21-22,27H,4,7-8,11,14-16H2/t19-,21+,22?/m0/s1 | PDB
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| 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178868
(CHEMBL203993 | trans-N-(3,5-dichlorobenzyl)-2-(1-h...)Show SMILES OC(CCc1ccc(OC(F)(F)F)cc1)[C@@H]1CCC[C@H]1C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C23H24Cl2F3NO3/c24-16-10-15(11-17(25)12-16)13-29-22(31)20-3-1-2-19(20)21(30)9-6-14-4-7-18(8-5-14)32-23(26,27)28/h4-5,7-8,10-12,19-21,30H,1-3,6,9,13H2,(H,29,31)/t19-,20-,21?/m1/s1 | PDB
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| 870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178869
(CHEMBL206758 | trans-N-(3,5-dichlorobenzyl)-2-(1-h...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H25Cl2NO2/c23-17-11-16(12-18(24)13-17)14-25-22(27)20-8-4-7-19(20)21(26)10-9-15-5-2-1-3-6-15/h1-3,5-6,11-13,19-21,26H,4,7-10,14H2,(H,25,27)/t19-,20-,21?/m1/s1 | PDB
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| 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178856
(1-(trans-2-((3,5-dichlorobenzyloxy)methyl)cyclopen...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1COCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H26Cl2O2/c23-19-11-17(12-20(24)13-19)14-26-15-18-7-4-8-21(18)22(25)10-9-16-5-2-1-3-6-16/h1-3,5-6,11-13,18,21-22,25H,4,7-10,14-15H2/t18-,21+,22?/m0/s1 | PDB
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| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178857
(CHEMBL206447 | trans-N-(3,5-dichlorobenzyl)-2-(1-h...)Show SMILES OC(CCc1ccccc1OC(F)(F)F)[C@@H]1CCC[C@H]1C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C23H24Cl2F3NO3/c24-16-10-14(11-17(25)12-16)13-29-22(31)19-6-3-5-18(19)20(30)9-8-15-4-1-2-7-21(15)32-23(26,27)28/h1-2,4,7,10-12,18-20,30H,3,5-6,8-9,13H2,(H,29,31)/t18-,19-,20?/m1/s1 | PDB
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| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178855
(CHEMBL206225 | trans-N-(3,5-dichlorobenzyl)-2-(1-h...)Show SMILES COc1ccc(CCC(O)[C@@H]2CCC[C@H]2C(=O)NCc2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C23H27Cl2NO3/c1-29-19-8-5-15(6-9-19)7-10-22(27)20-3-2-4-21(20)23(28)26-14-16-11-17(24)13-18(25)12-16/h5-6,8-9,11-13,20-22,27H,2-4,7,10,14H2,1H3,(H,26,28)/t20-,21-,22?/m1/s1 | PDB
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| 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178870
(CHEMBL203995 | trans-N1-(4-(trifluoromethoxy)benzy...)Show SMILES CN(Cc1ccccc1)C(=O)[C@@H]1CCC[C@H]1C(=O)NCc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H25F3N2O3/c1-28(15-17-6-3-2-4-7-17)22(30)20-9-5-8-19(20)21(29)27-14-16-10-12-18(13-11-16)31-23(24,25)26/h2-4,6-7,10-13,19-20H,5,8-9,14-15H2,1H3,(H,27,29)/t19-,20-/m1/s1 | PDB
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| 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178858
(1-(trans-2-(4-(trifluoromethoxy)phenethoxy)cyclope...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1OCCc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C23H27F3O3/c24-23(25,26)29-19-12-9-18(10-13-19)15-16-28-22-8-4-7-20(22)21(27)14-11-17-5-2-1-3-6-17/h1-3,5-6,9-10,12-13,20-22,27H,4,7-8,11,14-16H2/t20-,21?,22+/m0/s1 | PDB
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| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178850
(1-(trans-2-(3,5-dichlorophenethoxy)cyclopentyl)-3-...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1OCCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H26Cl2O2/c23-18-13-17(14-19(24)15-18)11-12-26-22-8-4-7-20(22)21(25)10-9-16-5-2-1-3-6-16/h1-3,5-6,13-15,20-22,25H,4,7-12H2/t20-,21?,22+/m0/s1 | PDB
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UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178860
(3,5-dichloro-N-((trans-2-(1-hydroxy-3-phenylpropyl...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1CNS(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H25Cl2NO3S/c22-17-11-18(23)13-19(12-17)28(26,27)24-14-16-7-4-8-20(16)21(25)10-9-15-5-2-1-3-6-15/h1-3,5-6,11-13,16,20-21,24-25H,4,7-10,14H2/t16-,20+,21?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178852
(CHEMBL381051 | trans-N-(4-(trifluoromethoxy)benzyl...)Show SMILES CS(=O)(=O)c1ccc(CCC(O)[C@@H]2CCC[C@H]2C(=O)NCc2ccc(OC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C24H28F3NO5S/c1-34(31,32)19-12-7-16(8-13-19)9-14-22(29)20-3-2-4-21(20)23(30)28-15-17-5-10-18(11-6-17)33-24(25,26)27/h5-8,10-13,20-22,29H,2-4,9,14-15H2,1H3,(H,28,30)/t20-,21-,22?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178866
(CHEMBL205207 | trans-N-benzyl-2-(1-hydroxy-3-pheny...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1C(=O)NCc1ccccc1 Show InChI InChI=1S/C22H27NO2/c24-21(15-14-17-8-3-1-4-9-17)19-12-7-13-20(19)22(25)23-16-18-10-5-2-6-11-18/h1-6,8-11,19-21,24H,7,12-16H2,(H,23,25)/t19-,20-,21?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50178862
(3,5-dichloro-N-((trans-2-(1-hydroxy-3-phenylpropyl...)Show SMILES OC(CCc1ccccc1)[C@@H]1CCC[C@H]1CNC(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H25Cl2NO2/c23-18-11-17(12-19(24)13-18)22(27)25-14-16-7-4-8-20(16)21(26)10-9-15-5-2-1-3-6-15/h1-3,5-6,11-13,16,20-21,26H,4,7-10,14H2,(H,25,27)/t16-,20+,21?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of peripheral nerve sodium channel NaV1.7 |
Bioorg Med Chem Lett 16: 1358-61 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.051
BindingDB Entry DOI: 10.7270/Q2FX791S |
More data for this
Ligand-Target Pair | |
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