BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50009014
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079458 (2,6-Dimethyl-4-[3-methyl-5-(2-naphthalen-1-yl-ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079458 (2,6-Dimethyl-4-[3-methyl-5-(2-naphthalen-1-yl-ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079463 (4-{5-[2-(3-Bromo-phenyl)-ethyl]-3-phenyl-isoxazol-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079463 (4-{5-[2-(3-Bromo-phenyl)-ethyl]-3-phenyl-isoxazol-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079459 (4-[5-(2-Biphenyl-4-yl-ethyl)-3-methyl-isoxazol-4-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079464 (2,6-Dimethyl-4-[3-methyl-5-(2-naphthalen-2-yl-ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079459 (4-[5-(2-Biphenyl-4-yl-ethyl)-3-methyl-isoxazol-4-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079464 (2,6-Dimethyl-4-[3-methyl-5-(2-naphthalen-2-yl-ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079462 (2,6-Dimethyl-4-(3-methyl-5-phenethyl-isoxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079462 (2,6-Dimethyl-4-(3-methyl-5-phenethyl-isoxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079460 (4-{5-[2-(3-Methoxy-phenyl)-ethyl]-3-phenyl-isoxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079460 (4-{5-[2-(3-Methoxy-phenyl)-ethyl]-3-phenyl-isoxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079465 (4-[5-(2-Biphenyl-2-yl-ethyl)-3-methyl-isoxazol-4-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50079461 (2,6-Dimethyl-4-(5-phenethyl-3-phenyl-isoxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079461 (2,6-Dimethyl-4-(5-phenethyl-3-phenyl-isoxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50079465 (4-[5-(2-Biphenyl-2-yl-ethyl)-3-methyl-isoxazol-4-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair