Compile Data Set for Download or QSAR

Found 59 hits Enz. Inhib. hit(s) with all data for entry = 50009082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079941 ((8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...) Show SMILES COc1cccc2OCC(CNCC3CCN(CC3)c3ncccn3)Oc12 Show InChI InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)27-16(14-26-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against human Dopamine receptor D3				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079945 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2CCOc12 Show InChI InChI=1S/C23H28N2O3/c1-2-7-22-21(6-1)27-16-19(28-22)15-24-14-17-8-11-25(12-9-17)20-5-3-4-18-10-13-26-23(18)20/h1-7,17,19,24H,8-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079950 (CHEMBL430698 | N-(2,3-Dihydro-benzo[1,4]dioxin-2-y...) Show SMILES C(CNc1ncccn1)NCC1COc2ccccc2O1 Show InChI InChI=1S/C15H18N4O2/c1-2-5-14-13(4-1)20-11-12(21-14)10-16-8-9-19-15-17-6-3-7-18-15/h1-7,12,16H,8-11H2,(H,17,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against 5-hydroxytryptamine 1A receptor receptor				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) Show SMILES Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079940 (CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079940 (CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079947 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(3-me...) Show SMILES COc1cccc(c1)N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-19-6-4-5-18(13-19)24-11-9-17(10-12-24)14-23-15-20-16-26-21-7-2-3-8-22(21)27-20/h2-8,13,17,20,23H,9-12,14-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against human Dopamine receptor D2L				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079955 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(4-me...) Show SMILES COc1ccc(cc1)N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-19-8-6-18(7-9-19)24-12-10-17(11-13-24)14-23-15-20-16-26-21-4-2-3-5-22(21)27-20/h2-9,17,20,23H,10-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	15.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079950 (CHEMBL430698 | N-(2,3-Dihydro-benzo[1,4]dioxin-2-y...) Show SMILES C(CNc1ncccn1)NCC1COc2ccccc2O1 Show InChI InChI=1S/C15H18N4O2/c1-2-5-14-13(4-1)20-11-12(21-14)10-16-8-9-19-15-17-6-3-7-18-15/h1-7,12,16H,8-11H2,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079951 ((8-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3cccc(F)c3O2)CC1 Show InChI InChI=1S/C22H27FN2O3/c1-26-20-7-3-2-6-19(20)25-11-9-16(10-12-25)13-24-14-17-15-27-21-8-4-5-18(23)22(21)28-17/h2-8,16-17,24H,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079952 (CHEMBL112526 | [1-(2-Chloro-phenyl)-piperidin-4-yl...) Show SMILES Clc1ccccc1N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C21H25ClN2O2/c22-18-5-1-2-6-19(18)24-11-9-16(10-12-24)13-23-14-17-15-25-20-7-3-4-8-21(20)26-17/h1-8,16-17,23H,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079946 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H28N2O4/c1-2-6-21-20(5-1)28-16-18(29-21)15-24-14-17-8-10-25(11-9-17)19-4-3-7-22-23(19)27-13-12-26-22/h1-7,17-18,24H,8-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079944 (CHEMBL114852 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES COc1ccccc1NCC1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-20-7-3-2-6-19(20)23-14-17-10-12-24(13-11-17)15-18-16-26-21-8-4-5-9-22(21)27-18/h2-9,17-18,23H,10-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079940 (CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079940 (CHEMBL324076 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079946 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H28N2O4/c1-2-6-21-20(5-1)28-16-18(29-21)15-24-14-17-8-10-25(11-9-17)19-4-3-7-22-23(19)27-13-12-26-22/h1-7,17-18,24H,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079953 (3-({[1-(2-Methoxy-phenyl)-piperidin-4-ylmethyl]-am...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3cccc(O)c3O2)CC1 Show InChI InChI=1S/C22H28N2O4/c1-26-20-7-3-2-5-18(20)24-11-9-16(10-12-24)13-23-14-17-15-27-21-8-4-6-19(25)22(21)28-17/h2-8,16-17,23,25H,9-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against 5-hydroxytryptamine 7 receptor				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079938 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C20H25N3O2/c1-2-6-19-18(5-1)24-15-17(25-19)14-21-13-16-8-11-23(12-9-16)20-7-3-4-10-22-20/h1-7,10,16-17,21H,8-9,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079938 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C20H25N3O2/c1-2-6-19-18(5-1)24-15-17(25-19)14-21-13-16-8-11-23(12-9-16)20-7-3-4-10-22-20/h1-7,10,16-17,21H,8-9,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079951 ((8-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3cccc(F)c3O2)CC1 Show InChI InChI=1S/C22H27FN2O3/c1-26-20-7-3-2-6-19(20)25-11-9-16(10-12-25)13-24-14-17-15-27-21-8-4-5-18(23)22(21)28-17/h2-8,16-17,24H,9-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079943 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O2/c1-2-6-18(7-3-1)23-12-10-17(11-13-23)14-22-15-19-16-24-20-8-4-5-9-21(20)25-19/h1-9,17,19,22H,10-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079952 (CHEMBL112526 | [1-(2-Chloro-phenyl)-piperidin-4-yl...) Show SMILES Clc1ccccc1N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C21H25ClN2O2/c22-18-5-1-2-6-19(18)24-11-9-16(10-12-24)13-23-14-17-15-25-20-7-3-4-8-21(20)26-17/h1-8,16-17,23H,9-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079945 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2CCOc12 Show InChI InChI=1S/C23H28N2O3/c1-2-7-22-21(6-1)27-16-19(28-22)15-24-14-17-8-11-25(12-9-17)20-5-3-4-18-10-13-26-23(18)20/h1-7,17,19,24H,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079955 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(4-me...) Show SMILES COc1ccc(cc1)N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-19-8-6-18(7-9-19)24-12-10-17(11-13-24)14-23-15-20-16-26-21-4-2-3-5-22(21)27-20/h2-9,17,20,23H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079943 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O2/c1-2-6-18(7-3-1)23-12-10-17(11-13-23)14-22-15-19-16-24-20-8-4-5-9-21(20)25-19/h1-9,17,19,22H,10-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079947 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(3-me...) Show SMILES COc1cccc(c1)N1CCC(CNCC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-19-6-4-5-18(13-19)24-11-9-17(10-12-24)14-23-15-20-16-26-21-7-2-3-8-22(21)27-20/h2-8,13,17,20,23H,9-12,14-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against 5-hydroxytryptamine 2C receptor				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079954 ((5-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...) Show SMILES COc1cccc2OC(CNCC3CCN(CC3)c3ncccn3)COc12 Show InChI InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)26-14-16(27-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079944 (CHEMBL114852 | [1-(2,3-Dihydro-benzo[1,4]dioxin-2-...) Show SMILES COc1ccccc1NCC1CCN(CC2COc3ccccc3O2)CC1 Show InChI InChI=1S/C22H28N2O3/c1-25-20-7-3-2-6-19(20)23-14-17-10-12-24(13-11-17)15-18-16-26-21-8-4-5-9-22(21)27-18/h2-9,17-18,23H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	70.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against Dopamine receptor D4				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079941 ((8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...) Show SMILES COc1cccc2OCC(CNCC3CCN(CC3)c3ncccn3)Oc12 Show InChI InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)27-16(14-26-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079949 ((2-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES CC1(CNCC2CCN(CC2)c2ncccn2)COc2ccccc2O1 Show InChI InChI=1S/C20H26N4O2/c1-20(15-25-17-5-2-3-6-18(17)26-20)14-21-13-16-7-11-24(12-8-16)19-22-9-4-10-23-19/h2-6,9-10,16,21H,7-8,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079948 ((3-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES CC1Oc2ccccc2OC1CNCC1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C20H26N4O2/c1-15-19(26-18-6-3-2-5-17(18)25-15)14-21-13-16-7-11-24(12-8-16)20-22-9-4-10-23-20/h2-6,9-10,15-16,19,21H,7-8,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079954 ((5-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl...) Show SMILES COc1cccc2OC(CNCC3CCN(CC3)c3ncccn3)COc12 Show InChI InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)26-14-16(27-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079949 ((2-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES CC1(CNCC2CCN(CC2)c2ncccn2)COc2ccccc2O1 Show InChI InChI=1S/C20H26N4O2/c1-20(15-25-17-5-2-3-6-18(17)26-20)14-21-13-16-7-11-24(12-8-16)19-22-9-4-10-23-19/h2-6,9-10,16,21H,7-8,11-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079942 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-methyl-(...) Show SMILES CN(CC1CCN(CC1)c1ncccn1)CC1COc2ccccc2O1 Show InChI InChI=1S/C20H26N4O2/c1-23(14-17-15-25-18-5-2-3-6-19(18)26-17)13-16-7-11-24(12-8-16)20-21-9-4-10-22-20/h2-6,9-10,16-17H,7-8,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	359	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested binding affinity against 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand at 10e-6 M.				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested binding affinity against 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand at 10e-6 M.				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat))	BDBM50079939 ((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 Show InChI InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description The compound was tested for binding affinity against alpha-2D adrenergic receptor				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079948 ((3-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...) Show SMILES CC1Oc2ccccc2OC1CNCC1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C20H26N4O2/c1-15-19(26-18-6-3-2-5-17(18)25-15)14-21-13-16-7-11-24(12-8-16)20-22-9-4-10-23-20/h2-6,9-10,15-16,19,21H,7-8,11-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair

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