BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with all data for entry = 50009147
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human))	BDBM50080450 ((S)-5-Amino-2-{5-[(2-amino-4-oxo-3,4,5,6,7,8-hexah...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity of the compound as Competitive substrate in the presence of 50 gmM aminopterin towards recombinant Human Folyl-polyglutamate synthas...				J Med Chem 42: 3510-9 (1999) Article DOI: 10.1021/jm9807205 BindingDB Entry DOI: 10.7270/Q2X929GV
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Folylpolyglutamate synthase, mitochondrial (Homo sapiens (Human))	BDBM50080449 ((S)-5-Amino-2-{5-[(2-amino-4-oxo-3,4-dihydro-pyrid...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity of the compound as Competitive substrate in the presence of 50 gmM aminopterin towards recombinant Human Folyl-polyglutamate synthas...				J Med Chem 42: 3510-9 (1999) Article DOI: 10.1021/jm9807205 BindingDB Entry DOI: 10.7270/Q2X929GV
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair