Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with all data for entry = 50030850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302760 (CHEMBL568818 | N,N-diethyl-4-((1-(2-(furan-3-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccoc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302755 (CHEMBL569316 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccn2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C29H36N4O2/c1-3-32(4-2)29(35)23-11-13-25(14-12-23)33(27-9-7-10-28(34)22-27)26-16-20-31(21-17-26)19-15-24-8-5-6-18-30-24/h5-14,18,22,26,34H,3-4,15-17,19-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302759 (CHEMBL584941 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccsc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302756 (4-((1-(2-(1H-imidazol-2-yl)ethyl)piperidin-4-yl)(3...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ncc[nH]2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H35N5O2/c1-3-31(4-2)27(34)21-8-10-22(11-9-21)32(24-6-5-7-25(33)20-24)23-12-17-30(18-13-23)19-14-26-28-15-16-29-26/h5-11,15-16,20,23,33H,3-4,12-14,17-19H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302765 (CHEMBL569755 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h5-16,23,27,34H,3-4,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302758 (CHEMBL570000 | N,N-diethyl-4-((1-(2-(furan-2-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccco2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302763 (CHEMBL569728 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccc(C)cc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-13-15-27(16-14-26)34(29-7-6-8-30(35)23-29)28-18-21-32(22-19-28)20-17-25-11-9-24(3)10-12-25/h6-16,23,28,35H,4-5,17-22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302757 (CHEMBL568803 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccs2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302761 (CHEMBL569006 | N,N-diethyl-4-((1-(3-fluorophenethy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccc(F)c2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H36FN3O2/c1-3-33(4-2)30(36)24-11-13-26(14-12-24)34(28-9-6-10-29(35)22-28)27-16-19-32(20-17-27)18-15-23-7-5-8-25(31)21-23/h5-14,21-22,27,35H,3-4,15-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302762 (CHEMBL576267 | N,N-diethyl-4-((1-(2-fluorophenethy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2F)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H36FN3O2/c1-3-33(4-2)30(36)24-12-14-25(15-13-24)34(27-9-7-10-28(35)22-27)26-17-20-32(21-18-26)19-16-23-8-5-6-11-29(23)31/h5-15,22,26,35H,3-4,16-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302766 (4-((1-(2-cyclopropylethyl)piperidin-4-yl)(3-hydrox...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H37N3O2/c1-3-29(4-2)27(32)22-10-12-23(13-11-22)30(25-6-5-7-26(31)20-25)24-15-18-28(19-16-24)17-14-21-8-9-21/h5-7,10-13,20-21,24,31H,3-4,8-9,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302769 (CHEMBL571324 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(28)18-9-11-19(12-10-18)26(20-13-15-24(3)16-14-20)21-7-6-8-22(27)17-21/h6-12,17,20,27H,4-5,13-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302768 (4-((1-(but-3-enyl)piperidin-4-yl)(3-hydroxyphenyl)...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC=C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C26H35N3O2/c1-4-7-17-27-18-15-23(16-19-27)29(24-9-8-10-25(30)20-24)22-13-11-21(12-14-22)26(31)28(5-2)6-3/h4,8-14,20,23,30H,1,5-7,15-19H2,2-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302777 (CHEMBL569529 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccncc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C29H36N4O2/c1-3-32(4-2)29(35)24-8-10-25(11-9-24)33(27-6-5-7-28(34)22-27)26-15-20-31(21-16-26)19-14-23-12-17-30-18-13-23/h5-13,17-18,22,26,34H,3-4,14-16,19-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50039029 ((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r| Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302764 (CHEMBL568865 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC(C)c2ccccc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-14-16-27(17-15-26)34(29-12-9-13-30(35)22-29)28-18-20-32(21-19-28)23-24(3)25-10-7-6-8-11-25/h6-17,22,24,28,35H,4-5,18-21,23H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302776 (4-((1-(2-(1H-imidazol-4-yl)ethyl)piperidin-4-yl)(3...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cnc[nH]2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H35N5O2/c1-3-31(4-2)27(34)21-8-10-23(11-9-21)32(25-6-5-7-26(33)18-25)24-13-16-30(17-14-24)15-12-22-19-28-20-29-22/h5-11,18-20,24,33H,3-4,12-17H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302778 (CHEMBL570448 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2nccn2C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H37N5O2/c1-4-32(5-2)28(35)22-9-11-23(12-10-22)33(25-7-6-8-26(34)21-25)24-13-17-31(18-14-24)19-15-27-29-16-20-30(27)3/h6-12,16,20-21,24,34H,4-5,13-15,17-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302767 (4-((1-(2-cyclohexylethyl)piperidin-4-yl)(3-hydroxy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CCCCC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H43N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h8,11-16,23-24,27,34H,3-7,9-10,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302773 (CHEMBL570645 | N,N-diethyl-4-((3-methoxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccs2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C29H37N3O2S/c1-4-31(5-2)29(33)23-11-13-24(14-12-23)32(26-8-6-9-27(22-26)34-3)25-15-18-30(19-16-25)20-17-28-10-7-21-35-28/h6-14,21-22,25H,4-5,15-20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302771 (CHEMBL569704 | N,N-diethyl-4-((1-(2-(furan-3-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccoc2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C29H37N3O3/c1-4-31(5-2)29(33)24-9-11-25(12-10-24)32(27-7-6-8-28(21-27)34-3)26-14-18-30(19-15-26)17-13-23-16-20-35-22-23/h6-12,16,20-22,26H,4-5,13-15,17-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302774 (CHEMBL569945 | N,N-diethyl-4-((3-methoxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccsc2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C29H37N3O2S/c1-4-31(5-2)29(33)24-9-11-25(12-10-24)32(27-7-6-8-28(21-27)34-3)26-14-18-30(19-15-26)17-13-23-16-20-35-22-23/h6-12,16,20-22,26H,4-5,13-15,17-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302770 (4-((1-(2-(1H-imidazol-2-yl)ethyl)piperidin-4-yl)(3...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ncc[nH]2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C28H37N5O2/c1-4-32(5-2)28(34)22-9-11-23(12-10-22)33(25-7-6-8-26(21-25)35-3)24-13-18-31(19-14-24)20-15-27-29-16-17-30-27/h6-12,16-17,21,24H,4-5,13-15,18-20H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302772 (CHEMBL570446 | N,N-diethyl-4-((1-(2-(furan-2-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccco2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C29H37N3O3/c1-4-31(5-2)29(33)23-11-13-24(14-12-23)32(26-8-6-9-28(22-26)34-3)25-15-18-30(19-16-25)20-17-27-10-7-21-35-27/h6-14,21-22,25H,4-5,15-20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50302775 (CHEMBL569084 | N,N-diethyl-4-((3-methoxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2)CC1)c1cccc(OC)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(35)26-14-16-27(17-15-26)34(29-12-9-13-30(24-29)36-3)28-19-22-32(23-20-28)21-18-25-10-7-6-8-11-25/h6-17,24,28H,4-5,18-23H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]-[D-Ala2]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302763 (CHEMBL569728 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccc(C)cc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-13-15-27(16-14-26)34(29-7-6-8-30(35)23-29)28-18-21-32(22-19-28)20-17-25-11-9-24(3)10-12-25/h6-16,23,28,35H,4-5,17-22H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302769 (CHEMBL571324 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C23H31N3O2/c1-4-25(5-2)23(28)18-9-11-19(12-10-18)26(20-13-15-24(3)16-14-20)21-7-6-8-22(27)17-21/h6-12,17,20,27H,4-5,13-16H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302765 (CHEMBL569755 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h5-16,23,27,34H,3-4,17-22H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302768 (4-((1-(but-3-enyl)piperidin-4-yl)(3-hydroxyphenyl)...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC=C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C26H35N3O2/c1-4-7-17-27-18-15-23(16-19-27)29(24-9-8-10-25(30)20-24)22-13-11-21(12-14-22)26(31)28(5-2)6-3/h4,8-14,20,23,30H,1,5-7,15-19H2,2-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302758 (CHEMBL570000 | N,N-diethyl-4-((1-(2-(furan-2-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccco2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302760 (CHEMBL568818 | N,N-diethyl-4-((1-(2-(furan-3-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccoc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302766 (4-((1-(2-cyclopropylethyl)piperidin-4-yl)(3-hydrox...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H37N3O2/c1-3-29(4-2)27(32)22-10-12-23(13-11-22)30(25-6-5-7-26(31)20-25)24-15-18-28(19-16-24)17-14-21-8-9-21/h5-7,10-13,20-21,24,31H,3-4,8-9,14-19H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302759 (CHEMBL584941 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccsc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302768 (4-((1-(but-3-enyl)piperidin-4-yl)(3-hydroxyphenyl)...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC=C)CC1)c1cccc(O)c1 Show InChI InChI=1S/C26H35N3O2/c1-4-7-17-27-18-15-23(16-19-27)29(24-9-8-10-25(30)20-24)22-13-11-21(12-14-22)26(31)28(5-2)6-3/h4,8-14,20,23,30H,1,5-7,15-19H2,2-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302762 (CHEMBL576267 | N,N-diethyl-4-((1-(2-fluorophenethy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2F)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H36FN3O2/c1-3-33(4-2)30(36)24-12-14-25(15-13-24)34(27-9-7-10-28(35)22-27)26-17-20-32(21-18-26)19-16-23-8-5-6-11-29(23)31/h5-15,22,26,35H,3-4,16-21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302760 (CHEMBL568818 | N,N-diethyl-4-((1-(2-(furan-3-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccoc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302757 (CHEMBL568803 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccs2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302755 (CHEMBL569316 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccn2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C29H36N4O2/c1-3-32(4-2)29(35)23-11-13-25(14-12-23)33(27-9-7-10-28(34)22-27)26-16-20-31(21-17-26)19-15-24-8-5-6-18-30-24/h5-14,18,22,26,34H,3-4,15-17,19-21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302758 (CHEMBL570000 | N,N-diethyl-4-((1-(2-(furan-2-yl)et...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccco2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O3/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302767 (4-((1-(2-cyclohexylethyl)piperidin-4-yl)(3-hydroxy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CCCCC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H43N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h8,11-16,23-24,27,34H,3-7,9-10,17-22H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	289	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302776 (4-((1-(2-(1H-imidazol-4-yl)ethyl)piperidin-4-yl)(3...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cnc[nH]2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H35N5O2/c1-3-31(4-2)27(34)21-8-10-23(11-9-21)32(25-6-5-7-26(33)18-25)24-13-16-30(17-14-24)15-12-22-19-28-20-29-22/h5-11,18-20,24,33H,3-4,12-17H2,1-2H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50039029 ((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r| Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	352	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302757 (CHEMBL568803 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccs2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)22-10-12-23(13-11-22)31(25-7-5-8-26(32)21-25)24-14-17-29(18-15-24)19-16-27-9-6-20-34-27/h5-13,20-21,24,32H,3-4,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	453	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302761 (CHEMBL569006 | N,N-diethyl-4-((1-(3-fluorophenethy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2cccc(F)c2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H36FN3O2/c1-3-33(4-2)30(36)24-11-13-26(14-12-24)34(28-9-6-10-29(35)22-28)27-16-19-32(20-17-27)18-15-23-7-5-8-25(31)21-23/h5-14,21-22,27,35H,3-4,15-20H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	472	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302759 (CHEMBL584941 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccsc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C28H35N3O2S/c1-3-30(4-2)28(33)23-8-10-24(11-9-23)31(26-6-5-7-27(32)20-26)25-13-17-29(18-14-25)16-12-22-15-19-34-21-22/h5-11,15,19-21,25,32H,3-4,12-14,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	495	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302766 (4-((1-(2-cyclopropylethyl)piperidin-4-yl)(3-hydrox...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C27H37N3O2/c1-3-29(4-2)27(32)22-10-12-23(13-11-22)30(25-6-5-7-26(31)20-25)24-15-18-28(19-16-24)17-14-21-8-9-21/h5-7,10-13,20-21,24,31H,3-4,8-9,14-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	508	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50302764 (CHEMBL568865 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC(C)c2ccccc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-14-16-27(17-15-26)34(29-12-9-13-30(35)22-29)28-18-20-32(21-19-28)23-24(3)25-10-7-6-8-11-25/h6-17,22,24,28,35H,4-5,18-21,23H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	648	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302763 (CHEMBL569728 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccc(C)cc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C31H39N3O2/c1-4-33(5-2)31(36)26-13-15-27(16-14-26)34(29-7-6-8-30(35)23-29)28-18-21-32(22-19-28)20-17-25-11-9-24(3)10-12-25/h6-16,23,28,35H,4-5,17-22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	726	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302767 (4-((1-(2-cyclohexylethyl)piperidin-4-yl)(3-hydroxy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCC2CCCCC2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H43N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h8,11-16,23-24,27,34H,3-7,9-10,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	726	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50302765 (CHEMBL569755 | N,N-diethyl-4-((3-hydroxyphenyl)(1-...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CCc2ccccc2)CC1)c1cccc(O)c1 Show InChI InChI=1S/C30H37N3O2/c1-3-32(4-2)30(35)25-13-15-26(16-14-25)33(28-11-8-12-29(34)23-28)27-18-21-31(22-19-27)20-17-24-9-6-5-7-10-24/h5-16,23,27,34H,3-4,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	744	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Montr£al Curated by ChEMBL					Assay Description Displacement of [125I]D-pro10-dynorphin from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 5994-8 (2009) Article DOI: 10.1016/j.bmcl.2009.09.072 BindingDB Entry DOI: 10.7270/Q22J6BX8
					More data for this Ligand-Target Pair

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