Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50031797 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319488
(CHEMBL1084901 | rac-{5-Chloro-3-[2-(3,5-dimethyl-i...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccc(Cl)cc12 Show InChI InChI=1S/C24H22ClN3O5S/c1-13-19(15(3)33-26-13)11-28-24(17-6-4-5-7-21(17)34(28,31)32)23-14(2)27(12-22(29)30)20-9-8-16(25)10-18(20)23/h4-10,24H,11-12H2,1-3H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319486
(CHEMBL1084893 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C24H23N3O5S/c1-14-19(16(3)32-25-14)12-27-24(18-9-5-7-11-21(18)33(27,30)31)23-15(2)26(13-22(28)29)20-10-6-4-8-17(20)23/h4-11,24H,12-13H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319487
(CHEMBL1084894 | rac-{2-Methyl-3-[2-(3-methyl-5-phe...)Show SMILES Cc1noc(c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C29H25N3O5S/c1-18-23(29(37-30-18)20-10-4-3-5-11-20)16-32-28(22-13-7-9-15-25(22)38(32,35)36)27-19(2)31(17-26(33)34)24-14-8-6-12-21(24)27/h3-15,28H,16-17H2,1-2H3,(H,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319482
(CHEMBL1082939 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1cn(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C23H21N3O5S/c1-14-18(15(2)31-24-14)12-26-23(17-8-4-6-10-21(17)32(26,29)30)19-11-25(13-22(27)28)20-9-5-3-7-16(19)20/h3-11,23H,12-13H2,1-2H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319495
(CHEMBL1082610 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(CCS1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C20H23N3O5S/c1-12-16(14(3)28-21-12)10-23-18(8-9-29(23,26)27)20-13(2)22(11-19(24)25)17-7-5-4-6-15(17)20/h4-7,18H,8-11H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319486
(CHEMBL1084893 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C24H23N3O5S/c1-14-19(16(3)32-25-14)12-27-24(18-9-5-7-11-21(18)33(27,30)31)23-15(2)26(13-22(28)29)20-10-6-4-8-17(20)23/h4-11,24H,12-13H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human prostaglandin D2 receptor assessed as inhibition of PGD2-induced receptor activation by cell based FLIPR assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319490
(CHEMBL1084903 | rac-{3-[1,1-Dioxo-2-(2-phenoxy-eth...)Show SMILES Cc1c(C2N(CCOc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H24N2O5S/c1-18-25(20-11-5-7-13-22(20)27(18)17-24(29)30)26-21-12-6-8-14-23(21)34(31,32)28(26)15-16-33-19-9-3-2-4-10-19/h2-14,26H,15-17H2,1H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319491
(CHEMBL1083446 | rac-(3-{2-[2-(4-Chloro-phenoxy)-et...)Show SMILES Cc1c(C2N(CCOc3ccc(Cl)cc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H23ClN2O5S/c1-17-25(20-6-2-4-8-22(20)28(17)16-24(30)31)26-21-7-3-5-9-23(21)35(32,33)29(26)14-15-34-19-12-10-18(27)11-13-19/h2-13,26H,14-16H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319494
(CHEMBL1085069 | rac-{3-[2-(3,5-Dimethyl-isoxazol-4...)Show SMILES Cc1noc(C)c1CN1C(C)(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C25H25N3O5S/c1-15-19(17(3)33-26-15)13-28-25(4,20-10-6-8-12-22(20)34(28,31)32)24-16(2)27(14-23(29)30)21-11-7-5-9-18(21)24/h5-12H,13-14H2,1-4H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319489
(CHEMBL1084902 | rac-[3-(1,1-Dioxo-2-phenethyl-2,3-...)Show SMILES Cc1c(C2N(CCc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H24N2O4S/c1-18-25(20-11-5-7-13-22(20)27(18)17-24(29)30)26-21-12-6-8-14-23(21)33(31,32)28(26)16-15-19-9-3-2-4-10-19/h2-14,26H,15-17H2,1H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319477
(CHEMBL1086341 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(F)ccc2n1CC(O)=O Show InChI InChI=1S/C18H15FN2O4S/c1-10-17(18-12-4-2-3-5-15(12)26(24,25)20-18)13-8-11(19)6-7-14(13)21(10)9-16(22)23/h2-8,18,20H,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319485
(CHEMBL1085645 | rac-[3-(1,1-Dioxo-2-phenyl-2,3-dih...)Show SMILES Cc1c(C2N(c3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C24H20N2O4S/c1-16-23(18-11-5-7-13-20(18)25(16)15-22(27)28)24-19-12-6-8-14-21(19)31(29,30)26(24)17-9-3-2-4-10-17/h2-14,24H,15H2,1H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319483
(CHEMBL1085640 | rac-{2-Methyl-3-[2-(3-methyl-butyl...)Show SMILES CC(C)CCN1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C23H26N2O4S/c1-15(2)12-13-25-23(18-9-5-7-11-20(18)30(25,28)29)22-16(3)24(14-21(26)27)19-10-6-4-8-17(19)22/h4-11,15,23H,12-14H2,1-3H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319481
(CHEMBL1085639 | rac-[3-(1,1-Dioxo-2-phenethyl-2,3-...)Show SMILES OC(=O)Cn1cc(C2N(CCc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C25H22N2O4S/c28-24(29)17-26-16-21(19-10-4-6-12-22(19)26)25-20-11-5-7-13-23(20)32(30,31)27(25)15-14-18-8-2-1-3-9-18/h1-13,16,25H,14-15,17H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319476
(CHEMBL1083158 | rac-[5-Chloro-3-(1,1-dioxo-2,3-dih...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(Cl)ccc2n1CC(O)=O Show InChI InChI=1S/C18H15ClN2O4S/c1-10-17(18-12-4-2-3-5-15(12)26(24,25)20-18)13-8-11(19)6-7-14(13)21(10)9-16(22)23/h2-8,18,20H,9H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319484
(CHEMBL1085644 | rac-[3-(2-Isopropyl-1,1-dioxo-2,3-...)Show SMILES CC(C)N1C(c2ccccc2S1(=O)=O)c1c(C)n(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C21H22N2O4S/c1-13(2)23-21(16-9-5-7-11-18(16)28(23,26)27)20-14(3)22(12-19(24)25)17-10-6-4-8-15(17)20/h4-11,13,21H,12H2,1-3H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319480
(CHEMBL1086343 | rac-[3-(2-Benzyl-1,1-dioxo-2,3-dih...)Show SMILES OC(=O)Cn1cc(C2N(Cc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C24H20N2O4S/c27-23(28)16-25-15-20(18-10-4-6-12-21(18)25)24-19-11-5-7-13-22(19)31(29,30)26(24)14-17-8-2-1-3-9-17/h1-13,15,24H,14,16H2,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319492
(CHEMBL1083752 | rac-{3-[1,1-Dioxo-2-(3-phenoxy-pro...)Show SMILES Cc1c(C2N(CCCOc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C27H26N2O5S/c1-19-26(21-12-5-7-14-23(21)28(19)18-25(30)31)27-22-13-6-8-15-24(22)35(32,33)29(27)16-9-17-34-20-10-3-2-4-11-20/h2-8,10-15,27H,9,16-18H2,1H3,(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319493
(CHEMBL1086537 | rac-{3-[2-(2-Hydroxy-ethyl)-1,1-di...)Show SMILES Cc1c(C2N(CCO)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C20H20N2O5S/c1-13-19(14-6-2-4-8-16(14)21(13)12-18(24)25)20-15-7-3-5-9-17(15)28(26,27)22(20)10-11-23/h2-9,20,23H,10-12H2,1H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319475
(CHEMBL1082848 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2cc(C)ccc2n1CC(O)=O Show InChI InChI=1S/C19H18N2O4S/c1-11-7-8-15-14(9-11)18(12(2)21(15)10-17(22)23)19-13-5-3-4-6-16(13)26(24,25)20-19/h3-9,19-20H,10H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319499
(CHEMBL1086518 | rac-[5-Cyano-3-(1,1-dioxo-2,3-dihy...)Show SMILES OC(=O)Cn1cc(C2NS(=O)(=O)c3ccccc23)c2cc(ccc12)C#N Show InChI InChI=1S/C18H13N3O4S/c19-8-11-5-6-15-13(7-11)14(9-21(15)10-17(22)23)18-12-3-1-2-4-16(12)26(24,25)20-18/h1-7,9,18,20H,10H2,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319479
(CHEMBL1086560 | rac-{3-[2-(3-Methyl-butyl)-1,1-dio...)Show SMILES CC(C)CCN1C(c2ccccc2S1(=O)=O)c1cn(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C22H24N2O4S/c1-15(2)11-12-24-22(17-8-4-6-10-20(17)29(24,27)28)18-13-23(14-21(25)26)19-9-5-3-7-16(18)19/h3-10,13,15,22H,11-12,14H2,1-2H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319474
(CHEMBL1086519 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES Cc1c(C2NS(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C18H16N2O4S/c1-11-17(12-6-2-4-8-14(12)20(11)10-16(21)22)18-13-7-3-5-9-15(13)25(23,24)19-18/h2-9,18-19H,10H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319497
(CHEMBL1083734 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES Cc1ccc2n(CC(O)=O)cc(C3NS(=O)(=O)c4ccccc34)c2c1 Show InChI InChI=1S/C18H16N2O4S/c1-11-6-7-15-13(8-11)14(9-20(15)10-17(21)22)18-12-4-2-3-5-16(12)25(23,24)19-18/h2-9,18-19H,10H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319498
(CHEMBL1083735 | rac-[5-Chloro-3-(1,1-dioxo-2,3-dih...)Show SMILES OC(=O)Cn1cc(C2NS(=O)(=O)c3ccccc23)c2cc(Cl)ccc12 Show InChI InChI=1S/C17H13ClN2O4S/c18-10-5-6-14-12(7-10)13(8-20(14)9-16(21)22)17-11-3-1-2-4-15(11)25(23,24)19-17/h1-8,17,19H,9H2,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50319491
(CHEMBL1083446 | rac-(3-{2-[2-(4-Chloro-phenoxy)-et...)Show SMILES Cc1c(C2N(CCOc3ccc(Cl)cc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H23ClN2O5S/c1-17-25(20-6-2-4-8-22(20)28(17)16-24(30)31)26-21-7-3-5-9-23(21)35(32,33)29(26)14-15-34-19-12-10-18(27)11-13-19/h2-13,26H,14-16H2,1H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human thromboxane A2 receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50319490
(CHEMBL1084903 | rac-{3-[1,1-Dioxo-2-(2-phenoxy-eth...)Show SMILES Cc1c(C2N(CCOc3ccccc3)S(=O)(=O)c3ccccc23)c2ccccc2n1CC(O)=O Show InChI InChI=1S/C26H24N2O5S/c1-18-25(20-11-5-7-13-22(20)27(18)17-24(29)30)26-21-12-6-8-14-23(21)34(31,32)28(26)15-16-33-19-9-3-2-4-10-19/h2-14,26H,15-17H2,1H3,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human thromboxane A2 receptor by radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319478
(CHEMBL1086342 | rac-[3-(2-Methyl-1,1-dioxo-2,3-dih...)Show SMILES CN1C(c2ccccc2S1(=O)=O)c1cn(CC(O)=O)c2ccccc12 Show InChI InChI=1S/C18H16N2O4S/c1-19-18(13-7-3-5-9-16(13)25(19,23)24)14-10-20(11-17(21)22)15-8-4-2-6-12(14)15/h2-10,18H,11H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50319496
(CHEMBL1083733 | rac-[3-(1,1-Dioxo-2,3-dihydro-1H-1...)Show SMILES OC(=O)Cn1cc(C2NS(=O)(=O)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C17H14N2O4S/c20-16(21)10-19-9-13(11-5-1-3-7-14(11)19)17-12-6-2-4-8-15(12)24(22,23)18-17/h1-9,17-18H,10H2,(H,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human prostaglandin D2 receptor by cell based radioligand displacement assay |
Bioorg Med Chem Lett 20: 3287-90 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.046
BindingDB Entry DOI: 10.7270/Q26973QW |
More data for this
Ligand-Target Pair | |
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