Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with all data for entry = 50031816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319836 (4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1H-in...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H20ClF3N2O3/c28-21-13-18-9-12-33(15-16-1-5-20(6-2-16)27(29,30)31)23(18)22(14-21)24(34)32-26(10-11-26)19-7-3-17(4-8-19)25(35)36/h1-9,12-14H,10-11,15H2,(H,32,34)(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting in presence of 10%...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319840 ((S)-4-(1-(1-(3-chloro-5-(trifluoromethoxy)benzyl)-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cc(Cl)cc(OC(F)(F)F)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O4/c1-15(17-5-7-19(8-6-17)25(34)35)31-24(33)22-4-2-3-18-9-10-32(23(18)22)14-16-11-20(27)13-21(12-16)36-26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319838 ((S)-4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O3/c1-15(17-4-6-18(7-5-17)25(34)35)31-24(33)22-13-21(27)12-19-10-11-32(23(19)22)14-16-2-8-20(9-3-16)26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319839 ((S)-4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-7-9-20(10-8-18)25(33)34)30-24(32)22-4-2-3-19-13-14-31(23(19)22)15-17-5-11-21(12-6-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319843 ((S)-4-(1-(5-chloro-1-(3-chlorobenzyl)-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20Cl2N2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319842 ((S)-4-(1-(1-(3-chlorobenzyl)-5-fluoro-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(F)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20ClFN2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319847 ((S)-4-(1-(1-(3-chlorobenzyl)-1H-indole-7-carboxami...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H21ClN2O3/c1-16(18-8-10-20(11-9-18)25(30)31)27-24(29)22-7-3-5-19-12-13-28(23(19)22)15-17-4-2-6-21(26)14-17/h2-14,16H,15H2,1H3,(H,27,29)(H,30,31)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319841 ((S)-4-(1-(1-(3-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(c3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-8-10-20(11-9-18)25(33)34)30-24(32)22-7-3-5-19-12-13-31(23(19)22)15-17-4-2-6-21(14-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319845 ((S)-4-(1-(3-chloro-1-(3-chlorobenzyl)-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2c(Cl)cn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20Cl2N2O3/c1-15(17-8-10-18(11-9-17)25(31)32)28-24(30)21-7-3-6-20-22(27)14-29(23(20)21)13-16-4-2-5-19(26)12-16/h2-12,14-15H,13H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319847 ((S)-4-(1-(1-(3-chlorobenzyl)-1H-indole-7-carboxami...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H21ClN2O3/c1-16(18-8-10-20(11-9-18)25(30)31)27-24(29)22-7-3-5-19-12-13-28(23(19)22)15-17-4-2-6-21(26)14-17/h2-14,16H,15H2,1H3,(H,27,29)(H,30,31)/t16-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319845 ((S)-4-(1-(3-chloro-1-(3-chlorobenzyl)-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2c(Cl)cn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20Cl2N2O3/c1-15(17-8-10-18(11-9-17)25(31)32)28-24(30)21-7-3-6-20-22(27)14-29(23(20)21)13-16-4-2-5-19(26)12-16/h2-12,14-15H,13H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319844 ((S)-4-(1-(1-(3-chlorobenzyl)-3-methyl-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2c(C)cn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23ClN2O3/c1-16-14-29(15-18-5-3-6-21(27)13-18)24-22(16)7-4-8-23(24)25(30)28-17(2)19-9-11-20(12-10-19)26(31)32/h3-14,17H,15H2,1-2H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319840 ((S)-4-(1-(1-(3-chloro-5-(trifluoromethoxy)benzyl)-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cc(Cl)cc(OC(F)(F)F)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O4/c1-15(17-5-7-19(8-6-17)25(34)35)31-24(33)22-4-2-3-18-9-10-32(23(18)22)14-16-11-20(27)13-21(12-16)36-26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319846 ((S)-4-(1-(1-(3-chlorobenzyl)-2-methyl-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2cc(C)n(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23ClN2O3/c1-16-13-21-6-4-8-23(24(21)29(16)15-18-5-3-7-22(27)14-18)25(30)28-17(2)19-9-11-20(12-10-19)26(31)32/h3-14,17H,15H2,1-2H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319843 ((S)-4-(1-(5-chloro-1-(3-chlorobenzyl)-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20Cl2N2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319838 ((S)-4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O3/c1-15(17-4-6-18(7-5-17)25(34)35)31-24(33)22-13-21(27)12-19-10-11-32(23(19)22)14-16-2-8-20(9-3-16)26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319842 ((S)-4-(1-(1-(3-chlorobenzyl)-5-fluoro-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(F)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20ClFN2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319846 ((S)-4-(1-(1-(3-chlorobenzyl)-2-methyl-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2cc(C)n(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23ClN2O3/c1-16-13-21-6-4-8-23(24(21)29(16)15-18-5-3-7-22(27)14-18)25(30)28-17(2)19-9-11-20(12-10-19)26(31)32/h3-14,17H,15H2,1-2H3,(H,28,30)(H,31,32)/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319836 (4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1H-in...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H20ClF3N2O3/c28-21-13-18-9-12-33(15-16-1-5-20(6-2-16)27(29,30)31)23(18)22(14-21)24(34)32-26(10-11-26)19-7-3-17(4-8-19)25(35)36/h1-9,12-14H,10-11,15H2,(H,32,34)(H,35,36)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	561	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319841 ((S)-4-(1-(1-(3-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(c3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-8-10-20(11-9-18)25(33)34)30-24(32)22-7-3-5-19-12-13-31(23(19)22)15-17-4-2-6-21(14-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	885	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319844 ((S)-4-(1-(1-(3-chlorobenzyl)-3-methyl-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cccc2c(C)cn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23ClN2O3/c1-16-14-29(15-18-5-3-6-21(27)13-18)24-22(16)7-4-8-23(24)25(30)28-17(2)19-9-11-20(12-10-19)26(31)32/h3-14,17H,15H2,1-2H3,(H,28,30)(H,31,32)/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319839 ((S)-4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-7-9-20(10-8-18)25(33)34)30-24(32)22-4-2-3-19-13-14-31(23(19)22)15-17-5-11-21(12-6-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGF2alpha from human prostanoid FP receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]SQ-29548 from human prostanoid TP receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP3 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP2 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP1 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human Prostanoid DP2 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Displacement of [3H]iloprost from human prostanoid IP receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319838 ((S)-4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O3/c1-15(17-4-6-18(7-5-17)25(34)35)31-24(33)22-13-21(27)12-19-10-11-32(23(19)22)14-16-2-8-20(9-3-16)26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319836 (4-(1-(5-chloro-1-(4-(trifluoromethyl)benzyl)-1H-in...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cc(Cl)cc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H20ClF3N2O3/c28-21-13-18-9-12-33(15-16-1-5-20(6-2-16)27(29,30)31)23(18)22(14-21)24(34)32-26(10-11-26)19-7-3-17(4-8-19)25(35)36/h1-9,12-14H,10-11,15H2,(H,32,34)(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319840 ((S)-4-(1-(1-(3-chloro-5-(trifluoromethoxy)benzyl)-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cc(Cl)cc(OC(F)(F)F)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H20ClF3N2O4/c1-15(17-5-7-19(8-6-17)25(34)35)31-24(33)22-4-2-3-18-9-10-32(23(18)22)14-16-11-20(27)13-21(12-16)36-26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319843 ((S)-4-(1-(5-chloro-1-(3-chlorobenzyl)-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(Cl)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20Cl2N2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319839 ((S)-4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-7-9-20(10-8-18)25(33)34)30-24(32)22-4-2-3-19-13-14-31(23(19)22)15-17-5-11-21(12-6-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319842 ((S)-4-(1-(1-(3-chlorobenzyl)-5-fluoro-1H-indole-7-...) Show SMILES C[C@H](NC(=O)c1cc(F)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H20ClFN2O3/c1-15(17-5-7-18(8-6-17)25(31)32)28-24(30)22-13-21(27)12-19-9-10-29(23(19)22)14-16-3-2-4-20(26)11-16/h2-13,15H,14H2,1H3,(H,28,30)(H,31,32)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319847 ((S)-4-(1-(1-(3-chlorobenzyl)-1H-indole-7-carboxami...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H21ClN2O3/c1-16(18-8-10-20(11-9-18)25(30)31)27-24(29)22-7-3-5-19-12-13-28(23(19)22)15-17-4-2-6-21(26)14-17/h2-14,16H,15H2,1H3,(H,27,29)(H,30,31)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319837 (4-(1-(1-(4-(trifluoromethyl)benzyl)-1H-indole-7-ca...) Show SMILES OC(=O)c1ccc(cc1)C1(CC1)NC(=O)c1cccc2ccn(Cc3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at prostanoid EP4 receptor in human whole blood assessed as inhibition of TNFalpha-induced IP-10 release in presence EP4 agonist ...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50319841 ((S)-4-(1-(1-(3-(trifluoromethyl)benzyl)-1H-indole-...) Show SMILES C[C@H](NC(=O)c1cccc2ccn(Cc3cccc(c3)C(F)(F)F)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H21F3N2O3/c1-16(18-8-10-20(11-9-18)25(33)34)30-24(32)22-7-3-5-19-12-13-31(23(19)22)15-17-4-2-6-21(14-17)26(27,28)29/h2-14,16H,15H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Ltd Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 20: 3760-3 (2010) Article DOI: 10.1016/j.bmcl.2010.04.065 BindingDB Entry DOI: 10.7270/Q20P106K
					More data for this Ligand-Target Pair