Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50010324 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093383
(2-(4-Trifluoromethyl-phenyl)-1H-benzoimidazole-4-c...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H10F3N3O/c16-15(17,18)9-6-4-8(5-7-9)14-20-11-3-1-2-10(13(19)22)12(11)21-14/h1-7H,(H2,19,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093359
(2-(4-Hydroxymethyl-phenyl)-1H-benzoimidazole-4-car...)Show InChI InChI=1S/C15H13N3O2/c16-14(20)11-2-1-3-12-13(11)18-15(17-12)10-6-4-9(8-19)5-7-10/h1-7,19H,8H2,(H2,16,20)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093384
(2-(3-Hydroxy-4-methoxy-phenyl)-1H-benzoimidazole-4...)Show InChI InChI=1S/C15H13N3O3/c1-21-12-6-5-8(7-11(12)19)15-17-10-4-2-3-9(14(16)20)13(10)18-15/h2-7,19H,1H3,(H2,16,20)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093372
(2-(4-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic...)Show InChI InChI=1S/C14H10ClN3O/c15-9-6-4-8(5-7-9)14-17-11-3-1-2-10(13(16)19)12(11)18-14/h1-7H,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093379
(2-(4-Cyano-phenyl)-1H-benzoimidazole-4-carboxylic ...)Show InChI InChI=1S/C15H10N4O/c16-8-9-4-6-10(7-5-9)15-18-12-3-1-2-11(14(17)20)13(12)19-15/h1-7H,(H2,17,20)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093362
(2-(3,4-Dimethoxy-phenyl)-1H-benzoimidazole-4-carbo...)Show InChI InChI=1S/C16H15N3O3/c1-21-12-7-6-9(8-13(12)22-2)16-18-11-5-3-4-10(15(17)20)14(11)19-16/h3-8H,1-2H3,(H2,17,20)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093361
(2-(4-Dimethylamino-phenyl)-1H-benzoimidazole-4-car...)Show InChI InChI=1S/C16H16N4O/c1-20(2)11-8-6-10(7-9-11)16-18-13-5-3-4-12(15(17)21)14(13)19-16/h3-9H,1-2H3,(H2,17,21)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093365
(2-Benzo[1,3]dioxol-5-yl-1H-benzoimidazole-4-carbox...)Show InChI InChI=1S/C15H11N3O3/c16-14(19)9-2-1-3-10-13(9)18-15(17-10)8-4-5-11-12(6-8)21-7-20-11/h1-6H,7H2,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093374
(2-(4-Hydroxy-phenyl)-1H-benzoimidazole-4-carboxyli...)Show InChI InChI=1S/C14H11N3O2/c15-13(19)10-2-1-3-11-12(10)17-14(16-11)8-4-6-9(18)7-5-8/h1-7,18H,(H2,15,19)(H,16,17) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093373
(2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE |...)Show InChI InChI=1S/C15H13N3O2/c1-20-10-5-2-4-9(8-10)15-17-12-7-3-6-11(14(16)19)13(12)18-15/h2-8H,1H3,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093375
(2-(3-Hydroxy-phenyl)-1H-benzoimidazole-4-carboxyli...)Show InChI InChI=1S/C14H11N3O2/c15-13(19)10-5-2-6-11-12(10)17-14(16-11)8-3-1-4-9(18)7-8/h1-7,18H,(H2,15,19)(H,16,17) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27684
(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)Show InChI InChI=1S/C15H13N3O2/c1-20-10-7-5-9(6-8-10)15-17-12-4-2-3-11(14(16)19)13(12)18-15/h2-8H,1H3,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093360
(2-(3-Hydroxymethyl-phenyl)-1H-benzoimidazole-4-car...)Show InChI InChI=1S/C15H13N3O2/c16-14(20)11-5-2-6-12-13(11)18-15(17-12)10-4-1-3-9(7-10)8-19/h1-7,19H,8H2,(H2,16,20)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093382
(2-(3-Trifluoromethyl-phenyl)-1H-benzoimidazole-4-c...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H10F3N3O/c16-15(17,18)9-4-1-3-8(7-9)14-20-11-6-2-5-10(13(19)22)12(11)21-14/h1-7H,(H2,19,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093377
(2-(4-Nitro-phenyl)-1H-benzoimidazole-4-carboxylic ...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H10N4O3/c15-13(19)10-2-1-3-11-12(10)17-14(16-11)8-4-6-9(7-5-8)18(20)21/h1-7H,(H2,15,19)(H,16,17) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093370
(4-(4-Carbamoyl-1H-benzoimidazol-2-yl)-benzoic acid...)Show SMILES CCOC(=O)c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C17H15N3O3/c1-2-23-17(22)11-8-6-10(7-9-11)16-19-13-5-3-4-12(15(18)21)14(13)20-16/h3-9H,2H2,1H3,(H2,18,21)(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093368
(2-(3-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic...)Show InChI InChI=1S/C14H10ClN3O/c15-9-4-1-3-8(7-9)14-17-11-6-2-5-10(13(16)19)12(11)18-14/h1-7H,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093385
(2-(2-Fluoro-phenyl)-1H-benzoimidazole-4-carboxylic...)Show InChI InChI=1S/C14H10FN3O/c15-10-6-2-1-4-8(10)14-17-11-7-3-5-9(13(16)19)12(11)18-14/h1-7H,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093380
(2-(3-Allyloxy-4-methoxy-phenyl)-1H-benzoimidazole-...)Show InChI InChI=1S/C18H17N3O3/c1-3-9-24-15-10-11(7-8-14(15)23-2)18-20-13-6-4-5-12(17(19)22)16(13)21-18/h3-8,10H,1,9H2,2H3,(H2,19,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093369
(2-(2-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic...)Show InChI InChI=1S/C14H10ClN3O/c15-10-6-2-1-4-8(10)14-17-11-7-3-5-9(13(16)19)12(11)18-14/h1-7H,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093378
(2-(2-Hydroxymethyl-phenyl)-1H-benzoimidazole-4-car...)Show InChI InChI=1S/C15H13N3O2/c16-14(20)11-6-3-7-12-13(11)18-15(17-12)10-5-2-1-4-9(10)8-19/h1-7,19H,8H2,(H2,16,20)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 10.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093366
(2-(4-Amino-phenyl)-1H-benzoimidazole-4-carboxylic ...)Show InChI InChI=1S/C14H12N4O/c15-9-6-4-8(5-7-9)14-17-11-3-1-2-10(13(16)19)12(11)18-14/h1-7H,15H2,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093386
(2-(4-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-4...)Show InChI InChI=1S/C15H13N3O3/c1-21-12-7-8(5-6-11(12)19)15-17-10-4-2-3-9(14(16)20)13(10)18-15/h2-7,19H,1H3,(H2,16,20)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27091
(2-phenyl-1H-1,3-benzodiazole-4-carboxamide | CHEMB...)Show InChI InChI=1S/C14H11N3O/c15-13(18)10-7-4-8-11-12(10)17-14(16-11)9-5-2-1-3-6-9/h1-8H,(H2,15,18)(H,16,17) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093387
(2-(4-Methoxy-phenyl)-1-methyl-1H-benzoimidazole-4-...)Show InChI InChI=1S/C16H15N3O2/c1-19-13-5-3-4-12(15(17)20)14(13)18-16(19)10-6-8-11(21-2)9-7-10/h3-9H,1-2H3,(H2,17,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093381
(2-(4-Triisopropylsilanyloxymethyl-phenyl)-1H-benzo...)Show SMILES CC(C)[Si](OCc1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O)(C(C)C)C(C)C Show InChI InChI=1S/C24H33N3O2Si/c1-15(2)30(16(3)4,17(5)6)29-14-18-10-12-19(13-11-18)24-26-21-9-7-8-20(23(25)28)22(21)27-24/h7-13,15-17H,14H2,1-6H3,(H2,25,28)(H,26,27) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27088
(1H-1,3-benzodiazole-4-carboxamide | 1H-benzimidazo...)Show InChI InChI=1S/C8H7N3O/c9-8(12)5-2-1-3-6-7(5)11-4-10-6/h1-4H,(H2,9,12)(H,10,11) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093363
(2-Methyl-1H-benzoimidazole-4-carboxylic acid amide...)Show InChI InChI=1S/C9H9N3O/c1-5-11-7-4-2-3-6(9(10)13)8(7)12-5/h2-4H,1H3,(H2,10,13)(H,11,12) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093371
(2-(2-Methoxy-phenyl)-1H-benzoimidazole-4-carboxyli...)Show InChI InChI=1S/C15H13N3O2/c1-20-12-8-3-2-5-9(12)15-17-11-7-4-6-10(14(16)19)13(11)18-15/h2-8H,1H3,(H2,16,19)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093364
(2-(3,4,5-Trimethoxy-phenyl)-1H-benzoimidazole-4-ca...)Show SMILES COc1cc(cc(OC)c1OC)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C17H17N3O4/c1-22-12-7-9(8-13(23-2)15(12)24-3)17-19-11-6-4-5-10(16(18)21)14(11)20-17/h4-8H,1-3H3,(H2,18,21)(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093376
(2-(2-Trifluoromethyl-phenyl)-1H-benzoimidazole-4-c...)Show InChI InChI=1S/C15H10F3N3O/c16-15(17,18)10-6-2-1-4-8(10)14-20-11-7-3-5-9(13(19)22)12(11)21-14/h1-7H,(H2,19,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093388
(4-(4-Carbamoyl-1H-benzoimidazol-2-yl)-benzoic acid...)Show InChI InChI=1S/C15H11N3O3/c16-13(19)10-2-1-3-11-12(10)18-14(17-11)8-4-6-9(7-5-8)15(20)21/h1-7H,(H2,16,19)(H,17,18)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093358
(2-Trifluoromethyl-1H-benzoimidazole-4-carboxylic a...)Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)8-14-5-3-1-2-4(7(13)16)6(5)15-8/h1-3H,(H2,13,16)(H,14,15) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093357
(4-Carbamoyl-2-(4-methoxy-phenyl)-benzoimidazole-1-...)Show SMILES COc1ccc(cc1)-c1nc2c(cccc2n1C(=O)OCc1ccccc1)C(N)=O Show InChI InChI=1S/C23H19N3O4/c1-29-17-12-10-16(11-13-17)22-25-20-18(21(24)27)8-5-9-19(20)26(22)23(28)30-14-15-6-3-2-4-7-15/h2-13H,14H2,1H3,(H2,24,27) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27506
(3-AB | 3-aminobenzamide | CHEMBL81977)Show InChI InChI=1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
| PubMed
| 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against PARP L713F protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50093367
(2-(4-Hydroxy-phenyl)-1H-benzoimidazole-4-carboxyli...)Show InChI InChI=1S/C14H10N2O3/c17-9-6-4-8(5-7-9)13-15-11-3-1-2-10(14(18)19)12(11)16-13/h1-7,17H,(H,15,16)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
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| 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University
Curated by ChEMBL
| Assay Description In vitro inhibition against human full length PARP protein |
J Med Chem 43: 4084-97 (2000)
BindingDB Entry DOI: 10.7270/Q2MP52HJ |
More data for this Ligand-Target Pair | |