Compile Data Set for Download or QSAR

Found 120 hits Enz. Inhib. hit(s) with all data for entry = 50010521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095656 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O2/c1-19-6-5-7-20(16-19)18-30-14-11-23(12-15-30)29-24(31)26(32,21-8-3-2-4-9-21)22-10-13-25(27,28)17-22/h2-9,16,22-23,32H,10-15,17-18H2,1H3,(H,29,31)/t22-,26+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095679 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hyd...) Show SMILES Oc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C25H30F2N2O3/c26-24(27)12-9-20(16-24)25(32,19-6-2-1-3-7-19)23(31)28-21-10-13-29(14-11-21)17-18-5-4-8-22(30)15-18/h1-8,15,20-21,30,32H,9-14,16-17H2,(H,28,31)/t20-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095662 (2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-pip...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)c1 Show InChI InChI=1S/C26H34N2O2/c1-20-8-7-9-21(18-20)19-28-16-14-24(15-17-28)27-25(29)26(30,23-12-5-6-13-23)22-10-3-2-4-11-22/h2-4,7-11,18,23-24,30H,5-6,12-17,19H2,1H3,(H,27,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095657 ((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)12-9-18(15-23)24(32,17-5-2-1-3-6-17)22(31)29-19-10-13-30(14-11-19)16-20-7-4-8-21(27)28-20/h1-8,18-19,32H,9-16H2,(H2,27,28)(H,29,31)/t18-,24+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095656 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O2/c1-19-6-5-7-20(16-19)18-30-14-11-23(12-15-30)29-24(31)26(32,21-8-3-2-4-9-21)22-10-13-25(27,28)17-22/h2-9,16,22-23,32H,10-15,17-18H2,1H3,(H,29,31)/t22-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Ability to inhibit binding of [3H]-NMS was determined by receptor binding assay using membranes from chinese hamster ovary (CHO) cells expressing clo...				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095680 (2-Cyclopentyl-2-hydroxy-N-[1-(5-methyl-thiophen-3-...) Show SMILES Cc1cc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)cs1 Show InChI InChI=1S/C24H32N2O2S/c1-18-15-19(17-29-18)16-26-13-11-22(12-14-26)25-23(27)24(28,21-9-5-6-10-21)20-7-3-2-4-8-20/h2-4,7-8,15,17,21-22,28H,5-6,9-14,16H2,1H3,(H,25,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095662 (2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-pip...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)c1 Show InChI InChI=1S/C26H34N2O2/c1-20-8-7-9-21(18-20)19-28-16-14-24(15-17-28)27-25(29)26(30,23-12-5-6-13-23)22-10-3-2-4-11-22/h2-4,7-11,18,23-24,30H,5-6,12-17,19H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095670 (CHEMBL147653 | N-(1-Benzyl-piperidin-4-yl)-2-(3,3-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H30F2N2O2/c26-24(27)14-11-21(17-24)25(31,20-9-5-2-6-10-20)23(30)28-22-12-15-29(16-13-22)18-19-7-3-1-4-8-19/h1-10,21-22,31H,11-18H2,(H,28,30)/t21-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095661 (CHEMBL146464 | N-(1-Benzyl-piperidin-4-yl)-2-cyclo...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H32N2O2/c28-24(25(29,22-13-7-8-14-22)21-11-5-2-6-12-21)26-23-15-17-27(18-16-23)19-20-9-3-1-4-10-20/h1-6,9-12,22-23,29H,7-8,13-19H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095653 (2-(3,3-Difluoro-cyclopentyl)-N-[1-(3-fluoro-benzyl...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2cccc(F)c2)CC1)c1ccccc1 Show InChI InChI=1S/C25H29F3N2O2/c26-21-8-4-5-18(15-21)17-30-13-10-22(11-14-30)29-23(31)25(32,19-6-2-1-3-7-19)20-9-12-24(27,28)16-20/h1-8,15,20,22,32H,9-14,16-17H2,(H,29,31)/t20-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095685 (CHEMBL356181 | N-[1-(4-Amino-3-fluoro-benzyl)-pipe...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)cc1F Show InChI InChI=1S/C25H30F3N3O2/c26-21-14-17(6-7-22(21)29)16-31-12-9-20(10-13-31)30-23(32)25(33,18-4-2-1-3-5-18)19-8-11-24(27,28)15-19/h1-7,14,19-20,33H,8-13,15-16,29H2,(H,30,32)/t19-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095661 (CHEMBL146464 | N-(1-Benzyl-piperidin-4-yl)-2-cyclo...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H32N2O2/c28-24(25(29,22-13-7-8-14-22)21-11-5-2-6-12-21)26-23-15-17-27(18-16-23)19-20-9-3-1-4-10-20/h1-6,9-12,22-23,29H,7-8,13-19H2,(H,26,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095657 ((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)12-9-18(15-23)24(32,17-5-2-1-3-6-17)22(31)29-19-10-13-30(14-11-19)16-20-7-4-8-21(27)28-20/h1-8,18-19,32H,9-16H2,(H2,27,28)(H,29,31)/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095653 (2-(3,3-Difluoro-cyclopentyl)-N-[1-(3-fluoro-benzyl...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2cccc(F)c2)CC1)c1ccccc1 Show InChI InChI=1S/C25H29F3N2O2/c26-21-8-4-5-18(15-21)17-30-13-10-22(11-14-30)29-23(31)25(32,19-6-2-1-3-7-19)20-9-12-24(27,28)16-20/h1-8,15,20,22,32H,9-14,16-17H2,(H,29,31)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095664 (CHEMBL422665 | N-[1-(3-Amino-benzyl)-piperidin-4-y...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C25H31F2N3O2/c26-24(27)12-9-20(16-24)25(32,19-6-2-1-3-7-19)23(31)29-22-10-13-30(14-11-22)17-18-5-4-8-21(28)15-18/h1-8,15,20,22,32H,9-14,16-17,28H2,(H,29,31)/t20-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095671 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H28F2N2O2S/c24-22(25)10-6-19(14-22)23(29,18-4-2-1-3-5-18)21(28)26-20-7-11-27(12-8-20)15-17-9-13-30-16-17/h1-5,9,13,16,19-20,29H,6-8,10-12,14-15H2,(H,26,28)/t19-,23+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095655 (CHEMBL343449 | N-[1-(4-Amino-benzyl)-piperidin-4-y...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)cc1 Show InChI InChI=1S/C25H31F2N3O2/c26-24(27)13-10-20(16-24)25(32,19-4-2-1-3-5-19)23(31)29-22-11-14-30(15-12-22)17-18-6-8-21(28)9-7-18/h1-9,20,22,32H,10-17,28H2,(H,29,31)/t20-,25+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095675 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...) Show SMILES COc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O3/c1-33-23-9-5-6-19(16-23)18-30-14-11-22(12-15-30)29-24(31)26(32,20-7-3-2-4-8-20)21-10-13-25(27,28)17-21/h2-9,16,21-22,32H,10-15,17-18H2,1H3,(H,29,31)/t21-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095680 (2-Cyclopentyl-2-hydroxy-N-[1-(5-methyl-thiophen-3-...) Show SMILES Cc1cc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)cs1 Show InChI InChI=1S/C24H32N2O2S/c1-18-15-19(17-29-18)16-26-13-11-22(12-14-26)25-23(27)24(28,21-9-5-6-10-21)20-7-3-2-4-8-20/h2-4,7-8,15,17,21-22,28H,5-6,9-14,16H2,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095676 (2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-pip...) Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)cc1 Show InChI InChI=1S/C26H34N2O2/c1-20-11-13-21(14-12-20)19-28-17-15-24(16-18-28)27-25(29)26(30,23-9-5-6-10-23)22-7-3-2-4-8-22/h2-4,7-8,11-14,23-24,30H,5-6,9-10,15-19H2,1H3,(H,27,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095677 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c26-22(23(27,20-8-4-5-9-20)19-6-2-1-3-7-19)24-21-10-13-25(14-11-21)16-18-12-15-28-17-18/h1-3,6-7,12,15,17,20-21,27H,4-5,8-11,13-14,16H2,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095670 (CHEMBL147653 | N-(1-Benzyl-piperidin-4-yl)-2-(3,3-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C25H30F2N2O2/c26-24(27)14-11-21(17-24)25(31,20-9-5-2-6-10-20)23(30)28-22-12-15-29(16-13-22)18-19-7-3-1-4-8-19/h1-10,21-22,31H,11-18H2,(H,28,30)/t21-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50079714 ((R)-2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-pent-3-...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6]-1-[#6]-[#6]-[#6]-[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H36N2O2/c1-19(2)9-8-16-26-17-14-22(15-18-26)25-23(27)24(28,21-12-6-7-13-21)20-10-4-3-5-11-20/h3-5,9-11,21-22,28H,6-8,12-18H2,1-2H3,(H,25,27)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095675 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-met...) Show SMILES COc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O3/c1-33-23-9-5-6-19(16-23)18-30-14-11-22(12-15-30)29-24(31)26(32,20-7-3-2-4-8-20)21-10-13-25(27,28)17-21/h2-9,16,21-22,32H,10-15,17-18H2,1H3,(H,29,31)/t21-,26+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095671 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H28F2N2O2S/c24-22(25)10-6-19(14-22)23(29,18-4-2-1-3-5-18)21(28)26-20-7-11-27(12-8-20)15-17-9-13-30-16-17/h1-5,9,13,16,19-20,29H,6-8,10-12,14-15H2,(H,26,28)/t19-,23+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095679 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hyd...) Show SMILES Oc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C25H30F2N2O3/c26-24(27)12-9-20(16-24)25(32,19-6-2-1-3-7-19)23(31)28-21-10-13-29(14-11-21)17-18-5-4-8-22(30)15-18/h1-8,15,20-21,30,32H,9-14,16-17H2,(H,28,31)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095683 (2-Cyclopentyl-2-hydroxy-N-[1-(3-methoxy-benzyl)-pi...) Show SMILES COc1cccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)c1 Show InChI InChI=1S/C26H34N2O3/c1-31-24-13-7-8-20(18-24)19-28-16-14-23(15-17-28)27-25(29)26(30,22-11-5-6-12-22)21-9-3-2-4-10-21/h2-4,7-10,13,18,22-23,30H,5-6,11-12,14-17,19H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095685 (CHEMBL356181 | N-[1-(4-Amino-3-fluoro-benzyl)-pipe...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)cc1F Show InChI InChI=1S/C25H30F3N3O2/c26-21-14-17(6-7-22(21)29)16-31-12-9-20(10-13-31)30-23(32)25(33,18-4-2-1-3-5-18)19-8-11-24(27,28)15-19/h1-7,14,19-20,33H,8-13,15-16,29H2,(H,30,32)/t19-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095654 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-met...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6@@H]-1-[#6]-[#6]C(F)(F)[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H34F2N2O2/c1-18(2)7-6-14-28-15-11-21(12-16-28)27-22(29)24(30,19-8-4-3-5-9-19)20-10-13-23(25,26)17-20/h3-5,7-9,20-21,30H,6,10-17H2,1-2H3,(H,27,29)/t20-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095676 (2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-pip...) Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)cc1 Show InChI InChI=1S/C26H34N2O2/c1-20-11-13-21(14-12-20)19-28-17-15-24(16-18-28)27-25(29)26(30,23-9-5-6-10-23)22-7-3-2-4-8-22/h2-4,7-8,11-14,23-24,30H,5-6,9-10,15-19H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095664 (CHEMBL422665 | N-[1-(3-Amino-benzyl)-piperidin-4-y...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C25H31F2N3O2/c26-24(27)12-9-20(16-24)25(32,19-6-2-1-3-7-19)23(31)29-22-10-13-30(14-11-22)17-18-5-4-8-21(28)15-18/h1-8,15,20,22,32H,9-14,16-17,28H2,(H,29,31)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095655 (CHEMBL343449 | N-[1-(4-Amino-benzyl)-piperidin-4-y...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)cc1 Show InChI InChI=1S/C25H31F2N3O2/c26-24(27)13-10-20(16-24)25(32,19-4-2-1-3-5-19)23(31)29-22-11-14-30(15-12-22)17-18-6-8-21(28)9-7-18/h1-9,20,22,32H,10-17,28H2,(H,29,31)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095683 (2-Cyclopentyl-2-hydroxy-N-[1-(3-methoxy-benzyl)-pi...) Show SMILES COc1cccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)c1 Show InChI InChI=1S/C26H34N2O3/c1-31-24-13-7-8-20(18-24)19-28-16-14-23(15-17-28)27-25(29)26(30,22-11-5-6-12-22)21-9-3-2-4-10-21/h2-4,7-10,13,18,22-23,30H,5-6,11-12,14-17,19H2,1H3,(H,27,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095659 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(6-met...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1 Show InChI InChI=1S/C25H31F2N3O2/c1-18-6-5-9-22(28-18)17-30-14-11-21(12-15-30)29-23(31)25(32,19-7-3-2-4-8-19)20-10-13-24(26,27)16-20/h2-9,20-21,32H,10-17H2,1H3,(H,29,31)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095677 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccsc2)CC1)c1ccccc1 Show InChI InChI=1S/C23H30N2O2S/c26-22(23(27,20-8-4-5-9-20)19-6-2-1-3-7-19)24-21-10-13-25(14-11-21)16-18-12-15-28-17-18/h1-3,6-7,12,15,17,20-21,27H,4-5,8-11,13-14,16H2,(H,24,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095688 (2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6@H]-1-[#6]-[#6]-[#6@@H](F)-[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H35FN2O2/c1-18(2)7-6-14-27-15-12-22(13-16-27)26-23(28)24(29,19-8-4-3-5-9-19)20-10-11-21(25)17-20/h3-5,7-9,20-22,29H,6,10-17H2,1-2H3,(H,26,28)/t20-,21+,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095660 (2-Cyclopentyl-2-hydroxy-N-[1-(6-methyl-pyridin-2-y...) Show SMILES Cc1cccc(CN2CCC(CC2)NC(=O)C(O)(C2CCCC2)c2ccccc2)n1 Show InChI InChI=1S/C25H33N3O2/c1-19-8-7-13-23(26-19)18-28-16-14-22(15-17-28)27-24(29)25(30,21-11-5-6-12-21)20-9-3-2-4-10-20/h2-4,7-10,13,21-22,30H,5-6,11-12,14-18H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095672 (CHEMBL148129 | N-(1-Cycloheptylmethyl-piperidin-4-...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(CC2CCCCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C26H40N2O2/c29-25(26(30,23-14-8-9-15-23)22-12-6-3-7-13-22)27-24-16-18-28(19-17-24)20-21-10-4-1-2-5-11-21/h3,6-7,12-13,21,23-24,30H,1-2,4-5,8-11,14-20H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095682 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C24H29F2N3O2/c25-23(26)12-9-19(16-23)24(31,18-6-2-1-3-7-18)22(30)28-20-10-14-29(15-11-20)17-21-8-4-5-13-27-21/h1-8,13,19-20,31H,9-12,14-17H2,(H,28,30)/t19-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095673 (2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-2-yl...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(Cc2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C24H31N3O2/c28-23(24(29,20-10-4-5-11-20)19-8-2-1-3-9-19)26-21-13-16-27(17-14-21)18-22-12-6-7-15-25-22/h1-3,6-9,12,15,20-21,29H,4-5,10-11,13-14,16-18H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095691 (CHEMBL148404 | N-[1-(5-Amino-pyridin-2-ylmethyl)-p...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)nc1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)11-8-18(14-23)24(32,17-4-2-1-3-5-17)22(31)29-20-9-12-30(13-10-20)16-21-7-6-19(27)15-28-21/h1-7,15,18,20,32H,8-14,16,27H2,(H,29,31)/t18-,24+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095691 (CHEMBL148404 | N-[1-(5-Amino-pyridin-2-ylmethyl)-p...) Show SMILES Nc1ccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)nc1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)11-8-18(14-23)24(32,17-4-2-1-3-5-17)22(31)29-20-9-12-30(13-10-20)16-21-7-6-19(27)15-28-21/h1-7,15,18,20,32H,8-14,16,27H2,(H,29,31)/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095682 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(Cc2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C24H29F2N3O2/c25-23(26)12-9-19(16-23)24(31,18-6-2-1-3-7-18)22(30)28-20-10-14-29(15-11-20)17-21-8-4-5-13-27-21/h1-8,13,19-20,31H,9-12,14-17H2,(H,28,30)/t19-,24+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095668 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-met...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6@H]-1-[#6]-[#6]C(F)(F)[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H34F2N2O2/c1-18(2)7-6-14-28-15-11-21(12-16-28)27-22(29)24(30,19-8-4-3-5-9-19)20-10-13-23(25,26)17-20/h3-5,7-9,20-21,30H,6,10-17H2,1-2H3,(H,27,29)/t20-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095687 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hyd...) Show SMILES OCc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O3/c27-25(28)12-9-22(16-25)26(33,21-7-2-1-3-8-21)24(32)29-23-10-13-30(14-11-23)17-19-5-4-6-20(15-19)18-31/h1-8,15,22-23,31,33H,9-14,16-18H2,(H,29,32)/t22-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095687 (2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hyd...) Show SMILES OCc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C26H32F2N2O3/c27-25(28)12-9-22(16-25)26(33,21-7-2-1-3-8-21)24(32)29-23-10-13-30(14-11-23)17-19-5-4-6-20(15-19)18-31/h1-8,15,22-23,31,33H,9-14,16-18H2,(H,29,32)/t22-,26+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095689 (CHEMBL149769 | N-(1-Cyclohexylmethyl-piperidin-4-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(CC2CCCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C25H38N2O2/c28-24(25(29,22-13-7-8-14-22)21-11-5-2-6-12-21)26-23-15-17-27(18-16-23)19-20-9-3-1-4-10-20/h2,5-6,11-12,20,22-23,29H,1,3-4,7-10,13-19H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095658 (CHEMBL146359 | N-(1-Cyclohexylmethyl-piperidin-4-y...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NC1CCN(CC2CCCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C25H36F2N2O2/c26-24(27)14-11-21(17-24)25(31,20-9-5-2-6-10-20)23(30)28-22-12-15-29(16-13-22)18-19-7-3-1-4-8-19/h2,5-6,9-10,19,21-22,31H,1,3-4,7-8,11-18H2,(H,28,30)/t21-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095686 (2-Hydroxy-2-(3-hydroxy-cyclopentyl)-N-[1-(4-methyl...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6@H]-1-[#6]-[#6]-[#6@H](-[#8])-[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H36N2O3/c1-18(2)7-6-14-26-15-12-21(13-16-26)25-23(28)24(29,19-8-4-3-5-9-19)20-10-11-22(27)17-20/h3-5,7-9,20-22,27,29H,6,10-17H2,1-2H3,(H,25,28)/t20-,22-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095669 (2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-[#7]-[#6](=O)[C@@]([#8])([#6@H]-1-[#6]-[#6]-[#6@H](F)-[#6]-1)c1ccccc1 Show InChI InChI=1S/C24H35FN2O2/c1-18(2)7-6-14-27-15-12-22(13-16-27)26-23(28)24(29,19-8-4-3-5-9-19)20-10-11-21(25)17-20/h3-5,7-9,20-22,29H,6,10-17H2,1-2H3,(H,26,28)/t20-,21-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair

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