Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with all data for entry = 50011334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12 Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12 Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105463 (2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...) Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12 Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) Show SMILES CCOc1ccc2nc3cc(N)ccc3c(N)c2c1 Show InChI InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) Show SMILES CCOc1ccc2nc3cc(N)ccc3c(N)c2c1 Show InChI InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM24709 (6,9-Diamino-2-Ethoxyacridine | 7-ethoxyacridine-3,...) Show SMILES CCOc1ccc2nc3cc(N)ccc3c(N)c2c1 Show InChI InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105462 (CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...) Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) Show SMILES Cc1cc2cc3cc(C)c(N)cc3nc2cc1N Show InChI InChI=1S/C15H15N3/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16/h3-7H,16-17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from underivatized resin				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) Show SMILES Cc1cc2cc3cc(C)c(N)cc3nc2cc1N Show InChI InChI=1S/C15H15N3/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16/h3-7H,16-17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) Show SMILES Cc1cc2cc3cc(C)c(N)cc3nc2cc1N Show InChI InChI=1S/C15H15N3/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16/h3-7H,16-17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri Curated by ChEMBL					Assay Description Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)				Bioorg Med Chem Lett 11: 2727-30 (2001) BindingDB Entry DOI: 10.7270/Q2PN94XJ
					More data for this Ligand-Target Pair