BindingDB PrimarySearch

Found 18 hits Enz. Inhib. hit(s) with all data for entry = 50011418
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50005480 ((-)-combretastatin \| (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50041119 (2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106310 (2,2-Dimethyl-propionic acid 6-(2-fluoro-phenyl)-8-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50012666 (2-((E)-Styryl)-3H-quinazolin-4-one \| 2-Styryl-3H-q...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM48563 (2-phenyl-1H-quinolin-4-one \| 2-phenyl-4-quinolone ...) Show SMILES Oc1cc(nc2ccccc12)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106308 (4-[6-(2-Fluoro-phenyl)-[1,3]dioxolo[4,5-g]quinolin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106307 (2-Phenyl-2,3-dihydro-1H-quinazolin-4-one \| CHEMBL1...) Show SMILES O=C1NC(Nc2ccccc12)c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106306 (CHEMBL338626 \| [6-(2-Fluoro-phenyl)-[1,3]dioxolo[4...) Show SMILES OC(=O)COc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106311 (6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...) Show SMILES Fc1ccccc1-c1cc(S)c2cc3OCOc3cc2n1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50041119 (2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...) Show SMILES Oc1cc(nc2cc3OCOc3cc12)-c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Percent inhibition of colchicine binding(ICB) at 5 uM [3H]-colchicine concentration				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106303 (4-[6-(2-Fluoro-phenyl)-[1,3]dioxolo[4,5-g]quinolin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106304 (CHEMBL129338 \| [6-(2-Fluoro-phenyl)-[1,3]dioxolo[4...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50044965 (1-Methyl-2-phenyl-1H-quinolin-4-one \| CHEMBL277048) Show SMILES Cn1c(cc(=O)c2ccccc12)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106305 (2-Phenyl-3H-quinazolin-4-one \| 2-phenyl-3,4-dihydr...) Show SMILES O=c1[nH]c(nc2ccccc12)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization.(ITP)				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106309 (2-(2'-fluorophenyl)-6-pyrolinyl-4-(1H)-quinolone \|...) Show SMILES Oc1cc(nc2ccc(cc12)N1CCCC1)-c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of colchicine binding(ICB). Tubulin concentration was 1 uM				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50106309 (2-(2'-fluorophenyl)-6-pyrolinyl-4-(1H)-quinolone \|...) Show SMILES Oc1cc(nc2ccc(cc12)N1CCCC1)-c1ccccc1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of colchicine binding(ICB). [3H]-colchicine concentration was 5 uM				J Med Chem 44: 3932-6 (2001) BindingDB Entry DOI: 10.7270/Q2PK0FFW
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair