BindingDB PrimarySearch

Found 38 hits Enz. Inhib. hit(s) with all data for entry = 50040825
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50400743 (CHEMBL2203549) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064957 (CHEMBL76806 \| N-(1-Benzyl-piperidin-4-yl)-2-(2-flu...) Show SMILES Fc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50400742 (CHEMBL2165453) Show SMILES C(Oc1cc(COc2ccccc2)no1)[C@@H]1CCCN1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2* nAChR in rat forebrain after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from human recombinant DAT after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha3beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50028091 ((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...) Show SMILES COCCCC\C(=N/OCCN)c1ccc(cc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50028094 ((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor; alpha2/beta4 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha2beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human recombinant NET after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha3beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50400740 (CHEMBL2165452) Show SMILES C(Oc1cc(COc2ccccc2)no1)[C@@H]1CCN1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	373	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from human recombinant DAT after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor; alpha2/beta4 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha2beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT2B receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from human recombinant histamine H2 receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha3beta4 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2* nAChR in rat forebrain after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]Iodopindolol from beta 2 adrenergic receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50400741 (CHEMBL2165447) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT6 receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM50400739 (CHEMBL2203550) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha3beta2 nAChR after 4 hrs by liquid scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50400738 (CHEMBL2203551) Show SMILES C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor after 1.5 hrs by microbeta scintillation counting analysis				ACS Med Chem Lett 3: 1054-1058 (2012) Article DOI: 10.1021/ml3002715 BindingDB Entry DOI: 10.7270/Q25M66WS
TBA Curated by ChEMBL					More data for this Ligand-Target Pair