Compile Data Set for Download or QSAR

Found 105 hits Enz. Inhib. hit(s) with all data for entry = 50044634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50403547 (ATROPEN | ATROPINE) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1 |r,THB:9:7:1:3.4| Show InChI InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic acetylcholine receptor subtype 5 expressed in CHO cell membranes by scintillation counting method				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 4 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 3 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 2 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 1 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (RAT)	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (RAT)	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat muscarinic acetylcholine receptor subtype 4 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat muscarinic acetylcholine receptor subtype 3 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat muscarinic acetylcholine receptor subtype 2 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat muscarinic acetylcholine receptor subtype 1 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023230 (CHEMBL1602658) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-12-25(13-11-19)31(27,28)20-8-9-21-22(16-20)30-15-14-29-21/h3-9,16,19H,2,10-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50023230 (CHEMBL1602658) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-12-25(13-11-19)31(27,28)20-8-9-21-22(16-20)30-15-14-29-21/h3-9,16,19H,2,10-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 4 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50023230 (CHEMBL1602658) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-12-25(13-11-19)31(27,28)20-8-9-21-22(16-20)30-15-14-29-21/h3-9,16,19H,2,10-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 3 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50023230 (CHEMBL1602658) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-12-25(13-11-19)31(27,28)20-8-9-21-22(16-20)30-15-14-29-21/h3-9,16,19H,2,10-15,17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 2 expressed in CHO cells co-transfected with chimeric Gqi5 by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50023230 (CHEMBL1602658) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-12-25(13-11-19)31(27,28)20-8-9-21-22(16-20)30-15-14-29-21/h3-9,16,19H,2,10-15,17H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human muscarinic acetylcholine receptor subtype 1 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023231 (CHEMBL3329715) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H26N2O3S/c1-2-22(17-18-9-5-3-6-10-18)21(24)19-13-15-23(16-14-19)27(25,26)20-11-7-4-8-12-20/h3-12,19H,2,13-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.17E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023232 (CHEMBL3329716) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N2O4S/c1-3-23(17-18-7-5-4-6-8-18)22(25)19-13-15-24(16-14-19)29(26,27)21-11-9-20(28-2)10-12-21/h4-12,19H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023233 (CHEMBL3329717) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1cccc(OC)c1 Show InChI InChI=1S/C22H28N2O4S/c1-3-23(17-18-8-5-4-6-9-18)22(25)19-12-14-24(15-13-19)29(26,27)21-11-7-10-20(16-21)28-2/h4-11,16,19H,3,12-15,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023234 (CHEMBL3329719) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C23H30N2O5S/c1-4-24(17-18-8-6-5-7-9-18)23(26)19-12-14-25(15-13-19)31(27,28)20-10-11-21(29-2)22(16-20)30-3/h5-11,16,19H,4,12-15,17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023235 (CHEMBL3329720) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1cccc2OCCOc12 Show InChI InChI=1S/C23H28N2O5S/c1-2-24(17-18-7-4-3-5-8-18)23(26)19-11-13-25(14-12-19)31(27,28)21-10-6-9-20-22(21)30-16-15-29-20/h3-10,19H,2,11-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023236 (CHEMBL3329722) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(C)s1 Show InChI InChI=1S/C20H26N2O3S2/c1-3-21(15-17-7-5-4-6-8-17)20(23)18-11-13-22(14-12-18)27(24,25)19-10-9-16(2)26-19/h4-10,18H,3,11-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023237 (CHEMBL3329728) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cccnc2c1 Show InChI InChI=1S/C24H27N3O3S/c1-2-26(18-19-7-4-3-5-8-19)24(28)21-12-15-27(16-13-21)31(29,30)22-11-10-20-9-6-14-25-23(20)17-22/h3-11,14,17,21H,2,12-13,15-16,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023238 (CHEMBL3329729) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2occc2c1 Show InChI InChI=1S/C23H26N2O4S/c1-2-24(17-18-6-4-3-5-7-18)23(26)19-10-13-25(14-11-19)30(27,28)21-8-9-22-20(16-21)12-15-29-22/h3-9,12,15-16,19H,2,10-11,13-14,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023239 (CHEMBL3329730) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C22H26N4O3S/c1-2-25(16-17-6-4-3-5-7-17)22(27)18-10-12-26(13-11-18)30(28,29)20-8-9-21-19(14-20)15-23-24-21/h3-9,14-15,18H,2,10-13,16H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023240 (CHEMBL3329731) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H26N4O3S/c1-2-25(16-17-6-4-3-5-7-17)22(27)18-10-12-26(13-11-18)30(28,29)20-9-8-19-15-23-24-21(19)14-20/h3-9,14-15,18H,2,10-13,16H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023241 (CHEMBL3329732) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2nsnc2c1 Show InChI InChI=1S/C21H24N4O3S2/c1-2-24(15-16-6-4-3-5-7-16)21(26)17-10-12-25(13-11-17)30(27,28)18-8-9-19-20(14-18)23-29-22-19/h3-9,14,17H,2,10-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023242 (CHEMBL3329734) Show SMILES CCN(Cc1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H26N2O5S/c1-2-23(15-17-6-4-3-5-7-17)22(25)18-10-12-24(13-11-18)30(26,27)19-8-9-20-21(14-19)29-16-28-20/h3-9,14,18H,2,10-13,15-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023243 (CHEMBL3329736) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(OC)cc1 |r| Show InChI InChI=1S/C23H30N2O4S/c1-4-25(18(2)19-8-6-5-7-9-19)23(26)20-14-16-24(17-15-20)30(27,28)22-12-10-21(29-3)11-13-22/h5-13,18,20H,4,14-17H2,1-3H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	977	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023244 (CHEMBL3329737) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2occc2c1 |r| Show InChI InChI=1S/C24H28N2O4S/c1-3-26(18(2)19-7-5-4-6-8-19)24(27)20-11-14-25(15-12-20)31(28,29)22-9-10-23-21(17-22)13-16-30-23/h4-10,13,16-18,20H,3,11-12,14-15H2,1-2H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	933	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023245 (CHEMBL3329738) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2OCCc2c1 |r| Show InChI InChI=1S/C24H30N2O4S/c1-3-26(18(2)19-7-5-4-6-8-19)24(27)20-11-14-25(15-12-20)31(28,29)22-9-10-23-21(17-22)13-16-30-23/h4-10,17-18,20H,3,11-16H2,1-2H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023246 (CHEMBL3329739) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2CCCc2c1 |r| Show InChI InChI=1S/C25H32N2O3S/c1-3-27(19(2)20-8-5-4-6-9-20)25(28)22-14-16-26(17-15-22)31(29,30)24-13-12-21-10-7-11-23(21)18-24/h4-6,8-9,12-13,18-19,22H,3,7,10-11,14-17H2,1-2H3/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	724	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023247 (CHEMBL3329740) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 |r| Show InChI InChI=1S/C23H28N4O3S/c1-3-27(17(2)18-7-5-4-6-8-18)23(28)19-11-13-26(14-12-19)31(29,30)21-10-9-20-16-24-25-22(20)15-21/h4-10,15-17,19H,3,11-14H2,1-2H3,(H,24,25)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023248 (CHEMBL3329741) Show SMILES CCN([C@H](C)c1ccccc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 |r| Show InChI InChI=1S/C23H28N4O3S/c1-3-27(17(2)18-7-5-4-6-8-18)23(28)19-11-13-26(14-12-19)31(29,30)21-9-10-22-20(15-21)16-24-25-22/h4-10,15-17,19H,3,11-14H2,1-2H3,(H,24,25)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	741	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023249 (CHEMBL3329742) Show SMILES CCN(Cc1ccc(F)cc1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H25FN4O3S/c1-2-26(15-16-3-6-19(23)7-4-16)22(28)17-9-11-27(12-10-17)31(29,30)20-8-5-18-14-24-25-21(18)13-20/h3-8,13-14,17H,2,9-12,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023250 (CHEMBL3329743) Show SMILES CCN(Cc1cccc(F)c1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H25FN4O3S/c1-2-26(15-16-4-3-5-19(23)12-16)22(28)17-8-10-27(11-9-17)31(29,30)20-7-6-18-14-24-25-21(18)13-20/h3-7,12-14,17H,2,8-11,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023251 (CHEMBL3329744) Show SMILES CCN(Cc1ccccc1F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H25FN4O3S/c1-2-26(15-18-5-3-4-6-20(18)23)22(28)16-9-11-27(12-10-16)31(29,30)19-8-7-17-14-24-25-21(17)13-19/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023252 (CHEMBL3329745) Show SMILES CCN(Cc1cccc(Cl)c1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H25ClN4O3S/c1-2-26(15-16-4-3-5-19(23)12-16)22(28)17-8-10-27(11-9-17)31(29,30)20-7-6-18-14-24-25-21(18)13-20/h3-7,12-14,17H,2,8-11,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023253 (CHEMBL3329746) Show SMILES CCN(Cc1cccc(OC)c1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H28N4O4S/c1-3-26(16-17-5-4-6-20(13-17)31-2)23(28)18-9-11-27(12-10-18)32(29,30)21-8-7-19-15-24-25-22(19)14-21/h4-8,13-15,18H,3,9-12,16H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023254 (CHEMBL3329747) Show SMILES CCN(Cc1cccc(C)c1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H28N4O3S/c1-3-26(16-18-6-4-5-17(2)13-18)23(28)19-9-11-27(12-10-19)31(29,30)21-8-7-20-15-24-25-22(20)14-21/h4-8,13-15,19H,3,9-12,16H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	871	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023255 (CHEMBL3329748) Show SMILES CCN(Cc1ccccc1C)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H28N4O3S/c1-3-26(16-20-7-5-4-6-17(20)2)23(28)18-10-12-27(13-11-18)31(29,30)21-9-8-19-15-24-25-22(19)14-21/h4-9,14-15,18H,3,10-13,16H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	871	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023256 (CHEMBL3329749) Show SMILES CCN(Cc1ccccc1OC)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H28N4O4S/c1-3-26(16-19-6-4-5-7-22(19)31-2)23(28)17-10-12-27(13-11-17)32(29,30)20-9-8-18-15-24-25-21(18)14-20/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023257 (CHEMBL3329750) Show SMILES CCN(Cc1ccccc1Cl)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C22H25ClN4O3S/c1-2-26(15-18-5-3-4-6-20(18)23)22(28)16-9-11-27(12-10-16)31(29,30)19-8-7-17-14-24-25-21(17)13-19/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023258 (CHEMBL3329751) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-18-5-3-4-6-20(18)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-8-7-17-14-27-28-21(17)13-19/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023259 (CHEMBL3329752) Show SMILES CCN(Cc1cccc(c1)C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2cn[nH]c2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-16-4-3-5-19(12-16)23(24,25)26)22(31)17-8-10-30(11-9-17)34(32,33)20-7-6-18-14-27-28-21(18)13-20/h3-7,12-14,17H,2,8-11,15H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023260 (CHEMBL3329754) Show SMILES CCN(Cc1ccccc1Cl)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C22H25ClN4O3S/c1-2-26(15-17-5-3-4-6-20(17)23)22(28)16-9-11-27(12-10-16)31(29,30)19-7-8-21-18(13-19)14-24-25-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023229 (CHEMBL3329755) Show SMILES CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C23H25F3N4O3S/c1-2-29(15-17-5-3-4-6-20(17)23(24,25)26)22(31)16-9-11-30(12-10-16)34(32,33)19-7-8-21-18(13-19)14-27-28-21/h3-8,13-14,16H,2,9-12,15H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023261 (CHEMBL3329756) Show SMILES CCCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C24H27F3N4O3S/c1-2-11-30(16-18-5-3-4-6-21(18)24(25,26)27)23(32)17-9-12-31(13-10-17)35(33,34)20-7-8-22-19(14-20)15-28-29-22/h3-8,14-15,17H,2,9-13,16H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	155	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023262 (CHEMBL3329757) Show SMILES FC(F)(F)c1ccccc1CN(CC=C)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C24H25F3N4O3S/c1-2-11-30(16-18-5-3-4-6-21(18)24(25,26)27)23(32)17-9-12-31(13-10-17)35(33,34)20-7-8-22-19(14-20)15-28-29-22/h2-8,14-15,17H,1,9-13,16H2,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023263 (CHEMBL3329758) Show SMILES CC(C)N(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C24H27F3N4O3S/c1-16(2)31(15-18-5-3-4-6-21(18)24(25,26)27)23(32)17-9-11-30(12-10-17)35(33,34)20-7-8-22-19(13-20)14-28-29-22/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50023264 (CHEMBL3329760) Show SMILES FC(F)(F)c1ccccc1CN(C1CCC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C25H27F3N4O3S/c26-25(27,28)22-7-2-1-4-18(22)16-32(20-5-3-6-20)24(33)17-10-12-31(13-11-17)36(34,35)21-8-9-23-19(14-21)15-29-30-23/h1-2,4,7-9,14-15,17,20H,3,5-6,10-13,16H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human muscarinic acetylcholine receptor subtype 5 expressed in CHO cells by calcium mobilization assay				J Med Chem 57: 7804-10 (2014) Article DOI: 10.1021/jm500995y BindingDB Entry DOI: 10.7270/Q2ST7RFM
					More data for this Ligand-Target Pair

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