Compile Data Set for Download or QSAR

Found 87 hits Enz. Inhib. hit(s) with all data for entry = 50013339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129387 ((R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hyd...) Show SMILES NC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C18H26N2O2/c19-16-10-12-20(13-11-16)17(21)18(22,15-8-4-5-9-15)14-6-2-1-3-7-14/h1-3,6-7,15-16,22H,4-5,8-13,19H2/t18-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129390 ((R)-1-[4-(2-Amino-ethyl)-4-ethyl-piperidin-1-yl]-2...) Show SMILES CCC1(CCN)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-2-20(10-13-25)11-14-26(15-12-20)19(27)22(28,17-6-4-3-5-7-17)18-8-9-21(23,24)16-18/h3-7,18,28H,2,8-16,25H2,1H3/t18-,22+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129399 ((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclope...) Show SMILES NCCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C20H30N2O2/c21-13-10-16-11-14-22(15-12-16)19(23)20(24,18-8-4-5-9-18)17-6-2-1-3-7-17/h1-3,6-7,16,18,24H,4-5,8-15,21H2/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129392 ((R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((...) Show SMILES [#7]-[#6]\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)[C@@]([#8])([#6@@H]-1-[#6]-[#6]C(F)(F)[#6]-1)c1ccccc1 Show InChI InChI=1S/C20H26F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-12-8-15(7-11-23)9-13-24/h1-5,7,17,26H,6,8-14,23H2/t17-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129392 ((R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((...) Show SMILES [#7]-[#6]\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)[C@@]([#8])([#6@@H]-1-[#6]-[#6]C(F)(F)[#6]-1)c1ccccc1 Show InChI InChI=1S/C20H26F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-12-8-15(7-11-23)9-13-24/h1-5,7,17,26H,6,8-14,23H2/t17-,20+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129387 ((R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hyd...) Show SMILES NC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C18H26N2O2/c19-16-10-12-20(13-11-16)17(21)18(22,15-8-4-5-9-15)14-6-2-1-3-7-14/h1-3,6-7,15-16,22H,4-5,8-13,19H2/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129397 ((R)-1-[4-(2-Amino-ethyl)-4-methyl-piperidin-1-yl]-...) Show SMILES CC1(CCN)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C21H30F2N2O2/c1-19(9-12-24)10-13-25(14-11-19)18(26)21(27,16-5-3-2-4-6-16)17-7-8-20(22,23)15-17/h2-6,17,27H,7-15,24H2,1H3/t17-,21+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095657 ((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)12-9-18(15-23)24(32,17-5-2-1-3-6-17)22(31)29-19-10-13-30(14-11-19)16-20-7-4-8-21(27)28-20/h1-8,18-19,32H,9-16H2,(H2,27,28)(H,29,31)/t18-,24+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129410 ((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl...) Show SMILES NCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28N2O2/c20-14-15-10-12-21(13-11-15)18(22)19(23,17-8-4-5-9-17)16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14,20H2/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129410 ((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl...) Show SMILES NCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28N2O2/c20-14-15-10-12-21(13-11-15)18(22)19(23,17-8-4-5-9-17)16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14,20H2/t19-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129409 ((R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-d...) Show SMILES NCC1CCN(C1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)8-6-15(10-17)18(24,14-4-2-1-3-5-14)16(23)22-9-7-13(11-21)12-22/h1-5,13,15,24H,6-12,21H2/t13?,15-,18+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129399 ((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclope...) Show SMILES NCCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C20H30N2O2/c21-13-10-16-11-14-22(15-12-16)19(23)20(24,18-8-4-5-9-18)17-6-2-1-3-7-17/h1-3,6-7,16,18,24H,4-5,8-15,21H2/t20-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095657 ((R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-...) Show SMILES Nc1cccc(CN2CCC(CC2)NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)n1 Show InChI InChI=1S/C24H30F2N4O2/c25-23(26)12-9-18(15-23)24(32,17-5-2-1-3-6-17)22(31)29-19-10-13-30(14-11-19)16-20-7-4-8-21(27)28-20/h1-8,18-19,32H,9-16H2,(H2,27,28)(H,29,31)/t18-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129409 ((R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-d...) Show SMILES NCC1CCN(C1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)8-6-15(10-17)18(24,14-4-2-1-3-5-14)16(23)22-9-7-13(11-21)12-22/h1-5,13,15,24H,6-12,21H2/t13?,15-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129404 ((R)-1-(4-Amino-piperidin-1-yl)-2-((R)-3,3-difluoro...) Show SMILES NC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)9-6-14(12-17)18(24,13-4-2-1-3-5-13)16(23)22-10-7-15(21)8-11-22/h1-5,14-15,24H,6-12,21H2/t14-,18+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129397 ((R)-1-[4-(2-Amino-ethyl)-4-methyl-piperidin-1-yl]-...) Show SMILES CC1(CCN)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C21H30F2N2O2/c1-19(9-12-24)10-13-25(14-11-19)18(26)21(27,16-5-3-2-4-6-16)17-7-8-20(22,23)15-17/h2-6,17,27H,7-15,24H2,1H3/t17-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129402 ((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-((R)-3,...) Show SMILES NCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-12-8-15(7-11-23)9-13-24/h1-5,15,17,26H,6-14,23H2/t17-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129393 ((R)-1-(4-Amino-4-methyl-piperidin-1-yl)-2-((R)-3,3...) Show SMILES CC1(N)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c1-17(22)9-11-23(12-10-17)16(24)19(25,14-5-3-2-4-6-14)15-7-8-18(20,21)13-15/h2-6,15,25H,7-13,22H2,1H3/t15-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129404 ((R)-1-(4-Amino-piperidin-1-yl)-2-((R)-3,3-difluoro...) Show SMILES NC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)9-6-14(12-17)18(24,13-4-2-1-3-5-13)16(23)22-10-7-15(21)8-11-22/h1-5,14-15,24H,6-12,21H2/t14-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129402 ((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-((R)-3,...) Show SMILES NCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-12-8-15(7-11-23)9-13-24/h1-5,15,17,26H,6-14,23H2/t17-,20+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129390 ((R)-1-[4-(2-Amino-ethyl)-4-ethyl-piperidin-1-yl]-2...) Show SMILES CCC1(CCN)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-2-20(10-13-25)11-14-26(15-12-20)19(27)22(28,17-6-4-3-5-7-17)18-8-9-21(23,24)16-18/h3-7,18,28H,2,8-16,25H2,1H3/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129393 ((R)-1-(4-Amino-4-methyl-piperidin-1-yl)-2-((R)-3,3...) Show SMILES CC1(N)CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c1-17(22)9-11-23(12-10-17)16(24)19(25,14-5-3-2-4-6-14)15-7-8-18(20,21)13-15/h2-6,15,25H,7-13,22H2,1H3/t15-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129398 ((R)-1-[4-(2-Amino-ethyl)-piperazin-1-yl]-2-((R)-3,...) Show SMILES NCCN1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H27F2N3O2/c20-18(21)7-6-16(14-18)19(26,15-4-2-1-3-5-15)17(25)24-12-10-23(9-8-22)11-13-24/h1-5,16,26H,6-14,22H2/t16-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129400 ((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-((R)-3,3-di...) Show SMILES NCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c20-18(21)9-6-16(12-18)19(25,15-4-2-1-3-5-15)17(24)23-10-7-14(13-22)8-11-23/h1-5,14,16,25H,6-13,22H2/t16-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129400 ((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-((R)-3,3-di...) Show SMILES NCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c20-18(21)9-6-16(12-18)19(25,15-4-2-1-3-5-15)17(24)23-10-7-14(13-22)8-11-23/h1-5,14,16,25H,6-13,22H2/t16-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129398 ((R)-1-[4-(2-Amino-ethyl)-piperazin-1-yl]-2-((R)-3,...) Show SMILES NCCN1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H27F2N3O2/c20-18(21)7-6-16(14-18)19(26,15-4-2-1-3-5-15)17(25)24-12-10-23(9-8-22)11-13-24/h1-5,16,26H,6-14,22H2/t16-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129387 ((R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hyd...) Show SMILES NC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C18H26N2O2/c19-16-10-12-20(13-11-16)17(21)18(22,15-8-4-5-9-15)14-6-2-1-3-7-14/h1-3,6-7,15-16,22H,4-5,8-13,19H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129389 ((R)-1-[1,4]Diazepan-1-yl-2-((R)-3,3-difluoro-cyclo...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)N1CCCNCC1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)8-7-15(13-17)18(24,14-5-2-1-3-6-14)16(23)22-11-4-9-21-10-12-22/h1-3,5-6,15,21,24H,4,7-13H2/t15-,18+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129391 ((R)-1-[4-(2-Amino-acetyl)-piperazin-1-yl]-2-((R)-3...) Show SMILES NCC(=O)N1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H25F2N3O3/c20-18(21)7-6-15(12-18)19(27,14-4-2-1-3-5-14)17(26)24-10-8-23(9-11-24)16(25)13-22/h1-5,15,27H,6-13,22H2/t15-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129389 ((R)-1-[1,4]Diazepan-1-yl-2-((R)-3,3-difluoro-cyclo...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)N1CCCNCC1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)8-7-15(13-17)18(24,14-5-2-1-3-6-14)16(23)22-11-4-9-21-10-12-22/h1-3,5-6,15,21,24H,4,7-13H2/t15-,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129403 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c20-18(21)9-6-16(12-18)19(25,15-4-2-1-3-5-15)17(24)23-13-14-7-10-22-11-8-14/h1-5,14,16,22,25H,6-13H2,(H,23,24)/t16-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129391 ((R)-1-[4-(2-Amino-acetyl)-piperazin-1-yl]-2-((R)-3...) Show SMILES NCC(=O)N1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C19H25F2N3O3/c20-18(21)7-6-15(12-18)19(27,14-4-2-1-3-5-14)17(26)24-10-8-23(9-11-24)16(25)13-22/h1-5,15,27H,6-13,22H2/t15-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129403 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C19H26F2N2O2/c20-18(21)9-6-16(12-18)19(25,15-4-2-1-3-5-15)17(24)23-13-14-7-10-22-11-8-14/h1-5,14,16,22,25H,6-13H2,(H,23,24)/t16-,19+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129384 ((R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]...) Show SMILES CC(C)(N)CC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-20(2,25)14-16-9-12-26(13-10-16)19(27)22(28,17-6-4-3-5-7-17)18-8-11-21(23,24)15-18/h3-7,16,18,28H,8-15,25H2,1-2H3/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129410 ((R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl...) Show SMILES NCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C19H28N2O2/c20-14-15-10-12-21(13-11-15)18(22)19(23,17-8-4-5-9-17)16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14,20H2/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129383 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C17H22F2N2O2/c18-16(19)7-6-14(12-16)17(23,13-4-2-1-3-5-13)15(22)21-10-8-20-9-11-21/h1-5,14,20,23H,6-12H2/t14-,17+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129384 ((R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]...) Show SMILES CC(C)(N)CC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-20(2,25)14-16-9-12-26(13-10-16)19(27)22(28,17-6-4-3-5-7-17)18-8-11-21(23,24)15-18/h3-7,16,18,28H,8-15,25H2,1-2H3/t18-,22+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129399 ((R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclope...) Show SMILES NCCC1CCN(CC1)C(=O)[C@@](O)(C1CCCC1)c1ccccc1 Show InChI InChI=1S/C20H30N2O2/c21-13-10-16-11-14-22(15-12-16)19(23)20(24,18-8-4-5-9-18)17-6-2-1-3-7-17/h1-3,6-7,16,18,24H,4-5,8-15,21H2/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129385 ((R)-1-[4-(3-Amino-propyl)-piperidin-1-yl]-2-((R)-3...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C21H30F2N2O2/c22-20(23)11-8-18(15-20)21(27,17-6-2-1-3-7-17)19(26)25-13-9-16(10-14-25)5-4-12-24/h1-3,6-7,16,18,27H,4-5,8-15,24H2/t18-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129383 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C17H22F2N2O2/c18-16(19)7-6-14(12-16)17(23,13-4-2-1-3-5-13)15(22)21-10-8-20-9-11-21/h1-5,14,20,23H,6-12H2/t14-,17+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129388 ((R)-N-(4-Aminomethyl-cyclohexyl)-2-((R)-3,3-difluo...) Show SMILES NCC1CCC(CC1)NC(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 |wU:11.11,wD:13.20,11.12,(15.87,-1.73,;14.54,-.96,;13.21,-1.73,;13.21,-3.27,;11.88,-4.04,;10.55,-3.27,;10.53,-1.73,;11.88,-.96,;9.22,-4.04,;7.87,-3.27,;7.87,-1.73,;6.54,-4.04,;7.87,-4.81,;5.77,-5.37,;6.38,-6.79,;5.23,-7.82,;3.9,-7.03,;2.57,-6.26,;3.5,-8.52,;4.23,-5.53,;5.21,-3.27,;3.86,-4.04,;2.54,-3.27,;2.54,-1.73,;3.86,-.96,;5.21,-1.73,)| Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)11-10-16(12-19)20(26,15-4-2-1-3-5-15)18(25)24-17-8-6-14(13-23)7-9-17/h1-5,14,16-17,26H,6-13,23H2,(H,24,25)/t14?,16-,17?,20+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129392 ((R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((...) Show SMILES [#7]-[#6]\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)[C@@]([#8])([#6@@H]-1-[#6]-[#6]C(F)(F)[#6]-1)c1ccccc1 Show InChI InChI=1S/C20H26F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-12-8-15(7-11-23)9-13-24/h1-5,7,17,26H,6,8-14,23H2/t17-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129406 ((R)-1-[4-(4-Amino-butyl)-piperidin-1-yl]-2-((R)-3,...) Show SMILES NCCCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c23-21(24)12-9-19(16-21)22(28,18-7-2-1-3-8-18)20(27)26-14-10-17(11-15-26)6-4-5-13-25/h1-3,7-8,17,19,28H,4-6,9-16,25H2/t19-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129405 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-p...) Show SMILES O[C@@]([C@@H]1CCC(F)(F)C1)(C(=O)NCCC1CCNCC1)c1ccccc1 Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)10-6-17(14-19)20(26,16-4-2-1-3-5-16)18(25)24-13-9-15-7-11-23-12-8-15/h1-5,15,17,23,26H,6-14H2,(H,24,25)/t17-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129385 ((R)-1-[4-(3-Amino-propyl)-piperidin-1-yl]-2-((R)-3...) Show SMILES NCCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C21H30F2N2O2/c22-20(23)11-8-18(15-20)21(27,17-6-2-1-3-7-17)19(26)25-13-9-16(10-14-25)5-4-12-24/h1-3,6-7,16,18,27H,4-5,8-15,24H2/t18-,21+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129396 ((R)-N-(3-Aminomethyl-phenyl)-2-((R)-3,3-difluoro-c...) Show SMILES NCc1cccc(NC(=O)[C@@](O)([C@@H]2CCC(F)(F)C2)c2ccccc2)c1 Show InChI InChI=1S/C20H22F2N2O2/c21-19(22)10-9-16(12-19)20(26,15-6-2-1-3-7-15)18(25)24-17-8-4-5-14(11-17)13-23/h1-8,11,16,26H,9-10,12-13,23H2,(H,24,25)/t16-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129388 ((R)-N-(4-Aminomethyl-cyclohexyl)-2-((R)-3,3-difluo...) Show SMILES NCC1CCC(CC1)NC(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 |wU:11.11,wD:13.20,11.12,(15.87,-1.73,;14.54,-.96,;13.21,-1.73,;13.21,-3.27,;11.88,-4.04,;10.55,-3.27,;10.53,-1.73,;11.88,-.96,;9.22,-4.04,;7.87,-3.27,;7.87,-1.73,;6.54,-4.04,;7.87,-4.81,;5.77,-5.37,;6.38,-6.79,;5.23,-7.82,;3.9,-7.03,;2.57,-6.26,;3.5,-8.52,;4.23,-5.53,;5.21,-3.27,;3.86,-4.04,;2.54,-3.27,;2.54,-1.73,;3.86,-.96,;5.21,-1.73,)| Show InChI InChI=1S/C20H28F2N2O2/c21-19(22)11-10-16(12-19)20(26,15-4-2-1-3-5-15)18(25)24-17-8-6-14(13-23)7-9-17/h1-5,14,16-17,26H,6-13,23H2,(H,24,25)/t14?,16-,17?,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50129407 ((R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-1-[...) Show SMILES CNCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C21H30F2N2O2/c1-24-12-8-16-9-13-25(14-10-16)19(26)21(27,17-5-3-2-4-6-17)18-7-11-20(22,23)15-18/h2-6,16,18,24,27H,7-15H2,1H3/t18-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50129409 ((R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-d...) Show SMILES NCC1CCN(C1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C18H24F2N2O2/c19-17(20)8-6-15(10-17)18(24,14-4-2-1-3-5-14)16(23)22-9-7-13(11-21)12-22/h1-5,13,15,24H,6-12,21H2/t13?,15-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50129406 ((R)-1-[4-(4-Amino-butyl)-piperidin-1-yl]-2-((R)-3,...) Show SMILES NCCCCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c23-21(24)12-9-19(16-21)22(28,18-7-2-1-3-8-18)20(27)26-14-10-17(11-15-26)6-4-5-13-25/h1-3,7-8,17,19,28H,4-6,9-16,25H2/t19-,22+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells				Bioorg Med Chem Lett 13: 2167-72 (2003) BindingDB Entry DOI: 10.7270/Q29G5M68
					More data for this Ligand-Target Pair

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