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Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50045008   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2C9


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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n/an/a>3.00E+3n/an/an/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human CYP2C9


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cytochrome P450 1A


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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n/an/a>3.00E+3n/an/an/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human CYP1A2


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cytochrome P450 3A


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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n/an/a>3.00E+3n/an/an/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human CYP3A4


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human CYP2D6


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041434
PNG
(CHEMBL3357365)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3CC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C20H29N3O2S/c1-20(2,3)10-19-21-17-9-15(26(24,25)16-12-22(4)13-16)7-8-18(17)23(19)11-14-5-6-14/h7-9,14,16H,5-6,10-13H2,1-4H3
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n/an/an/an/a 1.60E+3n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041435
PNG
(CHEMBL3357381)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC(C)(C)O)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C20H31N3O3S/c1-19(2,3)10-18-21-16-9-14(27(25,26)15-11-22(6)12-15)7-8-17(16)23(18)13-20(4,5)24/h7-9,15,24H,10-13H2,1-6H3
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041436
PNG
(CHEMBL3357382)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C)C1
Show InChI InChI=1S/C20H32N4O2S/c1-20(2,3)12-19-21-17-11-15(27(25,26)16-13-23(6)14-16)7-8-18(17)24(19)10-9-22(4)5/h7-8,11,16H,9-10,12-14H2,1-6H3
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n/an/an/an/a 1.60E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041437
PNG
(CHEMBL3357383)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3(O)CCOCC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C22H33N3O4S/c1-21(2,3)12-20-23-18-11-16(30(27,28)17-13-24(4)14-17)5-6-19(18)25(20)15-22(26)7-9-29-10-8-22/h5-6,11,17,26H,7-10,12-15H2,1-4H3
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RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041438
PNG
(CHEMBL3357384)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3CCN(CC3)C(C)=O)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C24H36N4O3S/c1-17(29)27-10-8-18(9-11-27)14-28-22-7-6-19(32(30,31)20-15-26(5)16-20)12-21(22)25-23(28)13-24(2,3)4/h6-7,12,18,20H,8-11,13-16H2,1-5H3
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041439
PNG
(CHEMBL3357385)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CCOC(F)(F)F)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C19H25F3N4O4S/c1-18(2,3)9-16-24-14-8-12(31(28,29)13-10-25(11-13)17(23)27)4-5-15(14)26(16)6-7-30-19(20,21)22/h4-5,8,13H,6-7,9-11H2,1-3H3,(H2,23,27)
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041440
PNG
(CHEMBL3357386)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC(C)(C)O)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H30N4O4S/c1-19(2,3)9-17-22-15-8-13(6-7-16(15)24(17)12-20(4,5)26)29(27,28)14-10-23(11-14)18(21)25/h6-8,14,26H,9-12H2,1-5H3,(H2,21,25)
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50006449
PNG
(CHEMBL3234675)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H31N5O3S/c1-20(2,3)11-18-22-16-10-14(6-7-17(16)25(18)9-8-23(4)5)29(27,28)15-12-24(13-15)19(21)26/h6-7,10,15H,8-9,11-13H2,1-5H3,(H2,21,26)
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041441
PNG
(CHEMBL3357387)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1(O)CCOCC1)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C22H32N4O5S/c1-21(2,3)11-19-24-17-10-15(32(29,30)16-12-25(13-16)20(23)27)4-5-18(17)26(19)14-22(28)6-8-31-9-7-22/h4-5,10,16,28H,6-9,11-14H2,1-3H3,(H2,23,27)
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n/an/an/an/a 1.00E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041442
PNG
(CHEMBL3357388)
Show SMILES CC(=O)N1CCC(Cn2c(CC(C)(C)C)nc3cc(ccc23)S(=O)(=O)C2CN(C2)C(N)=O)CC1
Show InChI InChI=1S/C24H35N5O4S/c1-16(30)27-9-7-17(8-10-27)13-29-21-6-5-18(11-20(21)26-22(29)12-24(2,3)4)34(32,33)19-14-28(15-19)23(25)31/h5-6,11,17,19H,7-10,12-15H2,1-4H3,(H2,25,31)
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RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041443
PNG
(CHEMBL3357389)
Show SMILES CCN1CC(C1)S(=O)(=O)c1ccc2n(CCN(C)C)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C21H34N4O2S/c1-7-24-14-17(15-24)28(26,27)16-8-9-19-18(12-16)22-20(13-21(2,3)4)25(19)11-10-23(5)6/h8-9,12,17H,7,10-11,13-15H2,1-6H3
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RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041444
PNG
(CHEMBL3357390)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CC(F)(F)F)C1
Show InChI InChI=1S/C21H31F3N4O2S/c1-20(2,3)11-19-25-17-10-15(6-7-18(17)28(19)9-8-26(4)5)31(29,30)16-12-27(13-16)14-21(22,23)24/h6-7,10,16H,8-9,11-14H2,1-5H3
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RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041432
PNG
(CHEMBL3357392)
Show SMILES COCCN1CC(C1)S(=O)(=O)c1ccc2n(CCN(C)C)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C22H36N4O3S/c1-22(2,3)14-21-23-19-13-17(7-8-20(19)26(21)10-9-24(4)5)30(27,28)18-15-25(16-18)11-12-29-6/h7-8,13,18H,9-12,14-16H2,1-6H3
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041433
PNG
(CHEMBL3357393)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C1)S(C)(=O)=O
Show InChI InChI=1S/C20H32N4O4S2/c1-20(2,3)12-19-21-17-11-15(7-8-18(17)24(19)10-9-22(4)5)30(27,28)16-13-23(14-16)29(6,25)26/h7-8,11,16H,9-10,12-14H2,1-6H3
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n/an/an/an/a>2.50E+4n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041445
PNG
(CHEMBL3357364)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)C1CNC1
Show InChI InChI=1S/C19H27N3O2S/c1-19(2,3)9-18-21-16-8-14(25(23,24)15-10-20-11-15)6-7-17(16)22(18)12-13-4-5-13/h6-8,13,15,20H,4-5,9-12H2,1-3H3
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n/an/an/an/a 8.90n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041434
PNG
(CHEMBL3357365)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3CC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C20H29N3O2S/c1-20(2,3)10-19-21-17-9-15(26(24,25)16-12-22(4)13-16)7-8-18(17)23(19)11-14-5-6-14/h7-9,14,16H,5-6,10-13H2,1-4H3
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n/an/an/an/a 2n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041444
PNG
(CHEMBL3357390)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CC(F)(F)F)C1
Show InChI InChI=1S/C21H31F3N4O2S/c1-20(2,3)11-19-25-17-10-15(6-7-18(17)28(19)9-8-26(4)5)31(29,30)16-12-27(13-16)14-21(22,23)24/h6-7,10,16H,8-9,11-14H2,1-5H3
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n/an/an/an/a 14n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041431
PNG
(CHEMBL3357367)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H28N4O3S/c1-20(2,3)9-18-22-16-8-14(6-7-17(16)24(18)10-13-4-5-13)28(26,27)15-11-23(12-15)19(21)25/h6-8,13,15H,4-5,9-12H2,1-3H3,(H2,21,25)
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n/an/an/an/a 1.20n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041447
PNG
(CHEMBL3357368)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)C1CCNCC1
Show InChI InChI=1S/C21H31N3O2S/c1-21(2,3)13-20-23-18-12-17(27(25,26)16-8-10-22-11-9-16)6-7-19(18)24(20)14-15-4-5-15/h6-7,12,15-16,22H,4-5,8-11,13-14H2,1-3H3
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n/an/an/an/a 62n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041448
PNG
(CHEMBL3357369)
Show SMILES CN1CCC(CC1)S(=O)(=O)c1ccc2n(CC3CC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C22H33N3O2S/c1-22(2,3)14-21-23-19-13-18(7-8-20(19)25(21)15-16-5-6-16)28(26,27)17-9-11-24(4)12-10-17/h7-8,13,16-17H,5-6,9-12,14-15H2,1-4H3
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n/an/an/an/a 37n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041449
PNG
(CHEMBL3357370)
Show SMILES CC(=O)N1CCC(CC1)S(=O)(=O)c1ccc2n(CC3CC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C23H33N3O3S/c1-16(27)25-11-9-18(10-12-25)30(28,29)19-7-8-21-20(13-19)24-22(14-23(2,3)4)26(21)15-17-5-6-17/h7-8,13,17-18H,5-6,9-12,14-15H2,1-4H3
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n/an/an/an/a 6.20n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041450
PNG
(CHEMBL3357371)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)C1CCN(CC1)C(N)=O
Show InChI InChI=1S/C22H32N4O3S/c1-22(2,3)13-20-24-18-12-17(6-7-19(18)26(20)14-15-4-5-15)30(28,29)16-8-10-25(11-9-16)21(23)27/h6-7,12,15-16H,4-5,8-11,13-14H2,1-3H3,(H2,23,27)
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n/an/an/an/a 6.30n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041451
PNG
(CHEMBL3357372)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)CC1CNC1
Show InChI InChI=1S/C20H29N3O2S/c1-20(2,3)9-19-22-17-8-16(26(24,25)13-15-10-21-11-15)6-7-18(17)23(19)12-14-4-5-14/h6-8,14-15,21H,4-5,9-13H2,1-3H3
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n/an/an/an/a 104n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041452
PNG
(CHEMBL3357373)
Show SMILES CN1CC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)C1
Show InChI InChI=1S/C21H31N3O2S/c1-21(2,3)10-20-22-18-9-17(27(25,26)14-16-11-23(4)12-16)7-8-19(18)24(20)13-15-5-6-15/h7-9,15-16H,5-6,10-14H2,1-4H3
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n/an/an/an/a 32n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041453
PNG
(CHEMBL3357374)
Show SMILES CC(=O)N1CC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)C1
Show InChI InChI=1S/C22H31N3O3S/c1-15(26)24-11-17(12-24)14-29(27,28)18-7-8-20-19(9-18)23-21(10-22(2,3)4)25(20)13-16-5-6-16/h7-9,16-17H,5-6,10-14H2,1-4H3
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n/an/an/an/a 73n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041454
PNG
(CHEMBL3357375)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)CC1CN(C1)C(N)=O
Show InChI InChI=1S/C21H30N4O3S/c1-21(2,3)9-19-23-17-8-16(6-7-18(17)25(19)12-14-4-5-14)29(27,28)13-15-10-24(11-15)20(22)26/h6-8,14-15H,4-5,9-13H2,1-3H3,(H2,22,26)
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n/an/an/an/a 13n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041455
PNG
(CHEMBL3357376)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)CC1CCNCC1
Show InChI InChI=1S/C22H33N3O2S/c1-22(2,3)13-21-24-19-12-18(6-7-20(19)25(21)14-16-4-5-16)28(26,27)15-17-8-10-23-11-9-17/h6-7,12,16-17,23H,4-5,8-11,13-15H2,1-3H3
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n/an/an/an/a 278n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041456
PNG
(CHEMBL3357377)
Show SMILES CN1CCC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)CC1
Show InChI InChI=1S/C23H35N3O2S/c1-23(2,3)14-22-24-20-13-19(7-8-21(20)26(22)15-17-5-6-17)29(27,28)16-18-9-11-25(4)12-10-18/h7-8,13,17-18H,5-6,9-12,14-16H2,1-4H3
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n/an/an/an/a 209n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041458
PNG
(CHEMBL3357378)
Show SMILES CC(=O)N1CCC(CS(=O)(=O)c2ccc3n(CC4CC4)c(CC(C)(C)C)nc3c2)CC1
Show InChI InChI=1S/C24H35N3O3S/c1-17(28)26-11-9-19(10-12-26)16-31(29,30)20-7-8-22-21(13-20)25-23(14-24(2,3)4)27(22)15-18-5-6-18/h7-8,13,18-19H,5-6,9-12,14-16H2,1-4H3
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n/an/an/an/a 7.70n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041459
PNG
(CHEMBL3357379)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)CC1CCN(CC1)C(N)=O
Show InChI InChI=1S/C23H34N4O3S/c1-23(2,3)13-21-25-19-12-18(6-7-20(19)27(21)14-16-4-5-16)31(29,30)15-17-8-10-26(11-9-17)22(24)28/h6-7,12,16-17H,4-5,8-11,13-15H2,1-3H3,(H2,24,28)
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n/an/an/an/a 0.990n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041460
PNG
(CHEMBL3357380)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CCOC(F)(F)F)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C19H26F3N3O3S/c1-18(2,3)10-17-23-15-9-13(29(26,27)14-11-24(4)12-14)5-6-16(15)25(17)7-8-28-19(20,21)22/h5-6,9,14H,7-8,10-12H2,1-4H3
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n/an/an/an/a 2.60n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041435
PNG
(CHEMBL3357381)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC(C)(C)O)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C20H31N3O3S/c1-19(2,3)10-18-21-16-9-14(27(25,26)15-11-22(6)12-15)7-8-17(16)23(18)13-20(4,5)24/h7-9,15,24H,10-13H2,1-6H3
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n/an/an/an/a 40n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041436
PNG
(CHEMBL3357382)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C)C1
Show InChI InChI=1S/C20H32N4O2S/c1-20(2,3)12-19-21-17-11-15(27(25,26)16-13-23(6)14-16)7-8-18(17)24(19)10-9-22(4)5/h7-8,11,16H,9-10,12-14H2,1-6H3
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n/an/an/an/a 12n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041437
PNG
(CHEMBL3357383)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3(O)CCOCC3)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C22H33N3O4S/c1-21(2,3)12-20-23-18-11-16(30(27,28)17-13-24(4)14-17)5-6-19(18)25(20)15-22(26)7-9-29-10-8-22/h5-6,11,17,26H,7-10,12-15H2,1-4H3
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n/an/an/an/a 7.90n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041438
PNG
(CHEMBL3357384)
Show SMILES CN1CC(C1)S(=O)(=O)c1ccc2n(CC3CCN(CC3)C(C)=O)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C24H36N4O3S/c1-17(29)27-10-8-18(9-11-27)14-28-22-7-6-19(32(30,31)20-15-26(5)16-20)12-21(22)25-23(28)13-24(2,3)4/h6-7,12,18,20H,8-11,13-16H2,1-5H3
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n/an/an/an/a 56n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041439
PNG
(CHEMBL3357385)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CCOC(F)(F)F)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C19H25F3N4O4S/c1-18(2,3)9-16-24-14-8-12(31(28,29)13-10-25(11-13)17(23)27)4-5-15(14)26(16)6-7-30-19(20,21)22/h4-5,8,13H,6-7,9-11H2,1-3H3,(H2,23,27)
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n/an/an/an/a 5.90n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041440
PNG
(CHEMBL3357386)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC(C)(C)O)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H30N4O4S/c1-19(2,3)9-17-22-15-8-13(6-7-16(15)24(17)12-20(4,5)26)29(27,28)14-10-23(11-14)18(21)25/h6-8,14,26H,9-12H2,1-5H3,(H2,21,25)
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n/an/an/an/a 14n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50006449
PNG
(CHEMBL3234675)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H31N5O3S/c1-20(2,3)11-18-22-16-10-14(6-7-17(16)25(18)9-8-23(4)5)29(27,28)15-12-24(13-15)19(21)26/h6-7,10,15H,8-9,11-13H2,1-5H3,(H2,21,26)
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n/an/an/an/a 4.80n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041441
PNG
(CHEMBL3357387)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1(O)CCOCC1)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C22H32N4O5S/c1-21(2,3)11-19-24-17-10-15(32(29,30)16-12-25(13-16)20(23)27)4-5-18(17)26(19)14-22(28)6-8-31-9-7-22/h4-5,10,16,28H,6-9,11-14H2,1-3H3,(H2,23,27)
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n/an/an/an/a 21n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041442
PNG
(CHEMBL3357388)
Show SMILES CC(=O)N1CCC(Cn2c(CC(C)(C)C)nc3cc(ccc23)S(=O)(=O)C2CN(C2)C(N)=O)CC1
Show InChI InChI=1S/C24H35N5O4S/c1-16(30)27-9-7-17(8-10-27)13-29-21-6-5-18(11-20(21)26-22(29)12-24(2,3)4)34(32,33)19-14-28(15-19)23(25)31/h5-6,11,17,19H,7-10,12-15H2,1-4H3,(H2,25,31)
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n/an/an/an/a 40n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041443
PNG
(CHEMBL3357389)
Show SMILES CCN1CC(C1)S(=O)(=O)c1ccc2n(CCN(C)C)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C21H34N4O2S/c1-7-24-14-17(15-24)28(26,27)16-8-9-19-18(12-16)22-20(13-21(2,3)4)25(19)11-10-23(5)6/h8-9,12,17H,7,10-11,13-15H2,1-6H3
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n/an/an/an/a 16n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041433
PNG
(CHEMBL3357393)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(C1)S(C)(=O)=O
Show InChI InChI=1S/C20H32N4O4S2/c1-20(2,3)12-19-21-17-11-15(7-8-18(17)24(19)10-9-22(4)5)30(27,28)16-13-23(14-16)29(6,25)26/h7-8,11,16H,9-10,12-14H2,1-6H3
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n/an/an/an/a 14n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041432
PNG
(CHEMBL3357392)
Show SMILES COCCN1CC(C1)S(=O)(=O)c1ccc2n(CCN(C)C)c(CC(C)(C)C)nc2c1
Show InChI InChI=1S/C22H36N4O3S/c1-22(2,3)14-21-23-19-13-17(7-8-20(19)26(21)10-9-24(4)5)30(27,28)18-15-25(16-18)11-12-29-6/h7-8,13,18H,9-12,14-16H2,1-6H3
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n/an/an/an/a 47n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50041430
PNG
(CHEMBL3357391)
Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)C1CN(CCO)C1
Show InChI InChI=1S/C21H34N4O3S/c1-21(2,3)13-20-22-18-12-16(6-7-19(18)25(20)9-8-23(4)5)29(27,28)17-14-24(15-17)10-11-26/h6-7,12,17,26H,8-11,13-15H2,1-5H3
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n/an/an/an/a 19n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50041431
PNG
(CHEMBL3357367)
Show SMILES CC(C)(C)Cc1nc2cc(ccc2n1CC1CC1)S(=O)(=O)C1CN(C1)C(N)=O
Show InChI InChI=1S/C20H28N4O3S/c1-20(2,3)9-18-22-16-8-14(6-7-17(16)24(18)10-13-4-5-13)28(26,27)15-11-23(12-15)19(21)25/h6-8,13,15H,4-5,9-12H2,1-3H3,(H2,21,25)
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n/an/an/an/a 2.80E+3n/an/an/an/a



RaQualia Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 25: 236-40 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.062
BindingDB Entry DOI: 10.7270/Q2GM88XM
More data for this
Ligand-Target Pair
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