Compile Data Set for Download or QSAR

Found 319 hits Enz. Inhib. hit(s) with all data for entry = 50014398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50142139 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(N-methyl...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(N)=N Show InChI InChI=1S/C22H20Cl2N6O2/c1-30(22(25)26)12-13-2-4-14(5-3-13)20(31)28-18-8-6-15(23)10-17(18)21(32)29-19-9-7-16(24)11-27-19/h2-11H,12H2,1H3,(H3,25,26)(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142169 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N'-dime...) Show SMILES CNC(=N)N(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22Cl2N6O2/c1-27-23(26)31(2)13-14-3-5-15(6-4-14)21(32)29-19-9-7-16(24)11-18(19)22(33)30-20-10-8-17(25)12-28-20/h3-12H,13H2,1-2H3,(H2,26,27)(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES CN(C)NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H21Cl2N5O2/c1-29(2)26-12-14-3-5-15(6-4-14)21(30)27-19-9-7-16(23)11-18(19)22(31)28-20-10-8-17(24)13-25-20/h3-11,13,26H,12H2,1-2H3,(H,27,30)(H,25,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142161 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[methyl-(...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCN1C |t:32| Show InChI InChI=1S/C25H24Cl2N6O2/c1-32-12-11-28-25(32)33(2)15-16-3-5-17(6-4-16)23(34)30-21-9-7-18(26)13-20(21)24(35)31-22-10-8-19(27)14-29-22/h3-10,13-14H,11-12,15H2,1-2H3,(H,30,34)(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142158 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-i...) Show SMILES NC1=NCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:1| Show InChI InChI=1S/C23H20Cl2N6O2/c24-16-5-7-19(18(11-16)22(33)30-20-8-6-17(25)12-28-20)29-21(32)15-3-1-14(2-4-15)13-31-10-9-27-23(31)26/h1-8,11-12H,9-10,13H2,(H2,26,27)(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142177 (2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(C)=N Show InChI InChI=1S/C23H21Cl2N5O2/c1-14(26)30(2)13-15-3-5-16(6-4-15)22(31)28-20-9-7-17(24)11-19(20)23(32)29-21-10-8-18(25)12-27-21/h3-12,26H,13H2,1-2H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142154 (CHEMBL174499 | {4-[4-Chloro-2-(5-chloro-pyridin-2-...) Show SMILES C[N+](C)(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22Cl2N4O2/c1-29(2,3)14-15-4-6-16(7-5-15)22(30)27-20-10-8-17(24)12-19(20)23(31)28-21-11-9-18(25)13-26-21/h4-13H,14H2,1-3H3,(H-,26,27,28,30,31)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142146 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-dimethylam...) Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H20Cl2N4O2/c1-28(2)13-14-3-5-15(6-4-14)21(29)26-19-9-7-16(23)11-18(19)22(30)27-20-10-8-17(24)12-25-20/h3-12H,13H2,1-2H3,(H,26,29)(H,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142163 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-o...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCOC3=N)cc2)nc1 Show InChI InChI=1S/C23H19Cl2N5O3/c24-16-5-7-19(18(11-16)22(32)29-20-8-6-17(25)12-27-20)28-21(31)15-3-1-14(2-4-15)13-30-9-10-33-23(30)26/h1-8,11-12,26H,9-10,13H2,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142163 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-o...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCOC3=N)cc2)nc1 Show InChI InChI=1S/C23H19Cl2N5O3/c24-16-5-7-19(18(11-16)22(32)29-20-8-6-17(25)12-27-20)28-21(31)15-3-1-14(2-4-15)13-30-9-10-33-23(30)26/h1-8,11-12,26H,9-10,13H2,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142161 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[methyl-(...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCN1C |t:32| Show InChI InChI=1S/C25H24Cl2N6O2/c1-32-12-11-28-25(32)33(2)15-16-3-5-17(6-4-16)23(34)30-21-9-7-18(26)13-20(21)24(35)31-22-10-8-19(27)14-29-22/h3-10,13-14H,11-12,15H2,1-2H3,(H,30,34)(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142169 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N'-dime...) Show SMILES CNC(=N)N(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22Cl2N6O2/c1-27-23(26)31(2)13-14-3-5-15(6-4-14)21(32)29-19-9-7-16(24)11-18(19)22(33)30-20-10-8-17(25)12-28-20/h3-12H,13H2,1-2H3,(H2,26,27)(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142154 (CHEMBL174499 | {4-[4-Chloro-2-(5-chloro-pyridin-2-...) Show SMILES C[N+](C)(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22Cl2N4O2/c1-29(2,3)14-15-4-6-16(7-5-15)22(30)27-20-10-8-17(24)12-19(20)23(31)28-21-11-9-18(25)13-26-21/h4-13H,14H2,1-3H3,(H-,26,27,28,30,31)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142178 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N',N''-...) Show SMILES CN\C(=N\C)N(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C24H24Cl2N6O2/c1-27-24(28-2)32(3)14-15-4-6-16(7-5-15)22(33)30-20-10-8-17(25)12-19(20)23(34)31-21-11-9-18(26)13-29-21/h4-13H,14H2,1-3H3,(H,27,28)(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142177 (2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(C)=N Show InChI InChI=1S/C23H21Cl2N5O2/c1-14(26)30(2)13-15-3-5-16(6-4-15)22(31)28-20-9-7-17(24)11-19(20)23(32)29-21-10-8-18(25)12-27-21/h3-12,26H,13H2,1-2H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142142 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...) Show SMILES CN(C)NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H21Cl2N5O2/c1-29(2)26-12-14-3-5-15(6-4-14)21(30)27-19-9-7-16(23)11-18(19)22(31)28-20-10-8-17(24)13-25-20/h3-11,13,26H,12H2,1-2H3,(H,27,30)(H,25,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142139 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(N-methyl...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(N)=N Show InChI InChI=1S/C22H20Cl2N6O2/c1-30(22(25)26)12-13-2-4-14(5-3-13)20(31)28-18-8-6-15(23)10-17(18)21(32)29-19-9-7-16(24)11-27-19/h2-11H,12H2,1H3,(H3,25,26)(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142135 (2-[4-({[2-(Acetimidoyl-methyl-amino)-ethyl]-methyl...) Show SMILES CN(CCN(C)C(C)=N)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C26H28Cl2N6O2/c1-17(29)34(3)13-12-33(2)16-18-4-6-19(7-5-18)25(35)31-23-10-8-20(27)14-22(23)26(36)32-24-11-9-21(28)15-30-24/h4-11,14-15,29H,12-13,16H2,1-3H3,(H,31,35)(H,30,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142184 (2'-Aminomethyl-biphenyl-4-carboxylic acid [4-chlor...) Show SMILES NCc1ccccc1-c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C26H20Cl2N4O2/c27-19-9-11-23(22(13-19)26(34)32-24-12-10-20(28)15-30-24)31-25(33)17-7-5-16(6-8-17)21-4-2-1-3-18(21)14-29/h1-13,15H,14,29H2,(H,31,33)(H,30,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142148 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-dimethy...) Show SMILES CN(C)C1=NCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:3| Show InChI InChI=1S/C25H24Cl2N6O2/c1-32(2)25-28-11-12-33(25)15-16-3-5-17(6-4-16)23(34)30-21-9-7-18(26)13-20(21)24(35)31-22-10-8-19(27)14-29-22/h3-10,13-14H,11-12,15H2,1-2H3,(H,30,34)(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142136 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-guanidinom...) Show SMILES NC(=N)NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C21H18Cl2N6O2/c22-14-5-7-17(16(9-14)20(31)29-18-8-6-15(23)11-26-18)28-19(30)13-3-1-12(2-4-13)10-27-21(24)25/h1-9,11H,10H2,(H,28,30)(H4,24,25,27)(H,26,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142158 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-i...) Show SMILES NC1=NCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:1| Show InChI InChI=1S/C23H20Cl2N6O2/c24-16-5-7-19(18(11-16)22(33)30-20-8-6-17(25)12-28-20)29-21(32)15-3-1-14(2-4-15)13-31-10-9-27-23(31)26/h1-8,11-12H,9-10,13H2,(H2,26,27)(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142138 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[(4,5-dih...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCO1 |t:32| Show InChI InChI=1S/C24H21Cl2N5O3/c1-31(24-27-10-11-34-24)14-15-2-4-16(5-3-15)22(32)29-20-8-6-17(25)12-19(20)23(33)30-21-9-7-18(26)13-28-21/h2-9,12-13H,10-11,14H2,1H3,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142145 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-({methyl-[...) Show SMILES CN(CCN(C)C(N)=N)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C25H27Cl2N7O2/c1-33(11-12-34(2)25(28)29)15-16-3-5-17(6-4-16)23(35)31-21-9-7-18(26)13-20(21)24(36)32-22-10-8-19(27)14-30-22/h3-10,13-14H,11-12,15H2,1-2H3,(H3,28,29)(H,31,35)(H,30,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142175 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[(4,5-dih...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCN1 |t:32| Show InChI InChI=1S/C24H22Cl2N6O2/c1-32(24-27-10-11-28-24)14-15-2-4-16(5-3-15)22(33)30-20-8-6-17(25)12-19(20)23(34)31-21-9-7-18(26)13-29-21/h2-9,12-13H,10-11,14H2,1H3,(H,27,28)(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142150 (1-{4-[4-Chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-...) Show SMILES C[N+]1(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CCCC1 Show InChI InChI=1S/C25H24Cl2N4O2/c1-31(12-2-3-13-31)16-17-4-6-18(7-5-17)24(32)29-22-10-8-19(26)14-21(22)25(33)30-23-11-9-20(27)15-28-23/h4-11,14-15H,2-3,12-13,16H2,1H3,(H-,28,29,30,32,33)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142147 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-methyli...) Show SMILES CNC1=NCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:2| Show InChI InChI=1S/C24H22Cl2N6O2/c1-27-24-28-10-11-32(24)14-15-2-4-16(5-3-15)22(33)30-20-8-6-17(25)12-19(20)23(34)31-21-9-7-18(26)13-29-21/h2-9,12-13H,10-11,14H2,1H3,(H,27,28)(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142179 (2-[4-(Acetimidoylamino-methyl)-benzoylamino]-5-chl...) Show SMILES CC(=N)NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O2/c1-13(25)26-11-14-2-4-15(5-3-14)21(30)28-19-8-6-16(23)10-18(19)22(31)29-20-9-7-17(24)12-27-20/h2-10,12H,11H2,1H3,(H2,25,26)(H,28,30)(H,27,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142157 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-t...) Show SMILES NC1=NCCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:1| Show InChI InChI=1S/C24H22Cl2N6O2/c25-17-6-8-20(19(12-17)23(34)31-21-9-7-18(26)13-29-21)30-22(33)16-4-2-15(3-5-16)14-32-11-1-10-28-24(32)27/h2-9,12-13H,1,10-11,14H2,(H2,27,28)(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142146 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-dimethylam...) Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H20Cl2N4O2/c1-28(2)13-14-3-5-15(6-4-14)21(29)26-19-9-7-16(23)11-18(19)22(30)27-20-10-8-17(24)12-25-20/h3-12H,13H2,1-2H3,(H,26,29)(H,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142144 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[4-(1-imin...) Show SMILES CC(=N)N1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1 Show InChI InChI=1S/C26H26Cl2N6O2/c1-17(29)34-12-10-33(11-13-34)16-18-2-4-19(5-3-18)25(35)31-23-8-6-20(27)14-22(23)26(36)32-24-9-7-21(28)15-30-24/h2-9,14-15,29H,10-13,16H2,1H3,(H,31,35)(H,30,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142167 (1-{4-[4-Chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(C[n+]3ccccc3)cc2)nc1 Show InChI InChI=1S/C25H18Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h1-15H,16H2,(H-,28,29,30,32,33)/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142180 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-[...) Show SMILES NC1=NCCCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |t:1| Show InChI InChI=1S/C25H24Cl2N6O2/c26-18-7-9-21(20(13-18)24(35)32-22-10-8-19(27)14-30-22)31-23(34)17-5-3-16(4-6-17)15-33-12-2-1-11-29-25(33)28/h3-10,13-14H,1-2,11-12,15H2,(H2,28,29)(H,31,34)(H,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142176 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[methyl-(...) Show SMILES CNCCN(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C24H25Cl2N5O2/c1-27-11-12-31(2)15-16-3-5-17(6-4-16)23(32)29-21-9-7-18(25)13-20(21)24(33)30-22-10-8-19(26)14-28-22/h3-10,13-14,27H,11-12,15H2,1-2H3,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142156 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[(2-dimet...) Show SMILES CN(C)CCN(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C25H27Cl2N5O2/c1-31(2)12-13-32(3)16-17-4-6-18(7-5-17)24(33)29-22-10-8-19(26)14-21(22)25(34)30-23-11-9-20(27)15-28-23/h4-11,14-15H,12-13,16H2,1-3H3,(H,29,33)(H,28,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142153 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-methylamin...) Show SMILES CNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C21H18Cl2N4O2/c1-24-11-13-2-4-14(5-3-13)20(28)26-18-8-6-15(22)10-17(18)21(29)27-19-9-7-16(23)12-25-19/h2-10,12,24H,11H2,1H3,(H,26,28)(H,25,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142160 (2-(4-Aminomethyl-benzoylamino)-5-chloro-N-(5-chlor...) Show SMILES NCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C20H16Cl2N4O2/c21-14-5-7-17(25-19(27)13-3-1-12(10-23)2-4-13)16(9-14)20(28)26-18-8-6-15(22)11-24-18/h1-9,11H,10,23H2,(H,25,27)(H,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142141 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[(4,5-dih...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCS1 |t:32| Show InChI InChI=1S/C24H21Cl2N5O2S/c1-31(24-27-10-11-34-24)14-15-2-4-16(5-3-15)22(32)29-20-8-6-17(25)12-19(20)23(33)30-21-9-7-18(26)13-28-21/h2-9,12-13H,10-11,14H2,1H3,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142172 (2-{4-[(Benzimidoyl-methyl-amino)-methyl]-benzoylam...) Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(=N)c1ccccc1 Show InChI InChI=1S/C28H23Cl2N5O2/c1-35(26(31)19-5-3-2-4-6-19)17-18-7-9-20(10-8-18)27(36)33-24-13-11-21(29)15-23(24)28(37)34-25-14-12-22(30)16-32-25/h2-16,31H,17H2,1H3,(H,33,36)(H,32,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142162 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(ethyl-me...) Show SMILES CCN(C)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22Cl2N4O2/c1-3-29(2)14-15-4-6-16(7-5-15)22(30)27-20-10-8-17(24)12-19(20)23(31)28-21-11-9-18(25)13-26-21/h4-13H,3,14H2,1-2H3,(H,27,30)(H,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142174 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(4-methyl-...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1 Show InChI InChI=1S/C25H25Cl2N5O2/c1-31-10-12-32(13-11-31)16-17-2-4-18(5-3-17)24(33)29-22-8-6-19(26)14-21(22)25(34)30-23-9-7-20(27)15-28-23/h2-9,14-15H,10-13,16H2,1H3,(H,29,33)(H,28,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142152 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142183 (2-[4-(4-Amino-piperidin-1-ylmethyl)-benzoylamino]-...) Show SMILES NC1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1 Show InChI InChI=1S/C25H25Cl2N5O2/c26-18-5-7-22(21(13-18)25(34)31-23-8-6-19(27)14-29-23)30-24(33)17-3-1-16(2-4-17)15-32-11-9-20(28)10-12-32/h1-8,13-14,20H,9-12,15,28H2,(H,30,33)(H,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142155 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-pyrrolidin...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCC3)cc2)nc1 Show InChI InChI=1S/C24H22Cl2N4O2/c25-18-7-9-21(20(13-18)24(32)29-22-10-8-19(26)14-27-22)28-23(31)17-5-3-16(4-6-17)15-30-11-1-2-12-30/h3-10,13-14H,1-2,11-12,15H2,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142159 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperazin-...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCNCC3)cc2)nc1 Show InChI InChI=1S/C24H23Cl2N5O2/c25-18-5-7-21(20(13-18)24(33)30-22-8-6-19(26)14-28-22)29-23(32)17-3-1-16(2-4-17)15-31-11-9-27-10-12-31/h1-8,13-14,27H,9-12,15H2,(H,29,32)(H,28,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142134 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-oxo-imi...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCNC3=O)cc2)nc1 Show InChI InChI=1S/C23H19Cl2N5O3/c24-16-5-7-19(18(11-16)22(32)29-20-8-6-17(25)12-27-20)28-21(31)15-3-1-14(2-4-15)13-30-10-9-26-23(30)33/h1-8,11-12H,9-10,13H2,(H,26,33)(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142168 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-diethylami...) Show SMILES CCN(CC)Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C24H24Cl2N4O2/c1-3-30(4-2)15-16-5-7-17(8-6-16)23(31)28-21-11-9-18(25)13-20(21)24(32)29-22-12-10-19(26)14-27-22/h5-14H,3-4,15H2,1-2H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142143 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-thioxo-...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCNC3=S)cc2)nc1 Show InChI InChI=1S/C23H19Cl2N5O2S/c24-16-5-7-19(18(11-16)22(32)29-20-8-6-17(25)12-27-20)28-21(31)15-3-1-14(2-4-15)13-30-10-9-26-23(30)33/h1-8,11-12H,9-10,13H2,(H,26,33)(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142149 (5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-hydrazinom...) Show SMILES NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C20H17Cl2N5O2/c21-14-5-7-17(26-19(28)13-3-1-12(2-4-13)10-25-23)16(9-14)20(29)27-18-8-6-15(22)11-24-18/h1-9,11,25H,10,23H2,(H,26,28)(H,24,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 319 total )  |  Next  |  Last  >>

Jump to: