Compile Data Set for Download or QSAR

Found 72 hits Enz. Inhib. hit(s) with all data for entry = 50014907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM50148952 (CHEMBL429152 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C31H30N6O4/c1-20(35-28(38)19-34-31(40)37-25-16-12-22(13-17-25)29(32)33)21-10-14-24(15-11-21)36-30(39)23-6-5-9-27(18-23)41-26-7-3-2-4-8-26/h2-18,20H,19H2,1H3,(H3,32,33)(H,35,38)(H,36,39)(H2,34,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148947 (CHEMBL339880 | Piperidine-4-carboxylic acid [4-(1-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)C2CCNCC2)cc1 Show InChI InChI=1S/C24H31N7O3/c1-15(16-2-6-19(7-3-16)30-23(33)18-10-12-27-13-11-18)29-21(32)14-28-24(34)31-20-8-4-17(5-9-20)22(25)26/h2-9,15,18,27H,10-14H2,1H3,(H3,25,26)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148950 (CHEMBL332753 | N-[1-(3-Bromo-4-morpholin-4-yl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(Br)c1 Show InChI InChI=1S/C22H27BrN6O3/c1-14(16-4-7-19(18(23)12-16)29-8-10-32-11-9-29)27-20(30)13-26-22(31)28-17-5-2-15(3-6-17)21(24)25/h2-7,12,14H,8-11,13H2,1H3,(H3,24,25)(H,27,30)(H2,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148953 (4-(1-{2-[3-(4-Carbamimidoyl-phenyl)-ureido]-acetyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H26N6O3/c1-16(17-7-9-19(10-8-17)24(33)30-20-5-3-2-4-6-20)29-22(32)15-28-25(34)31-21-13-11-18(12-14-21)23(26)27/h2-14,16H,15H2,1H3,(H3,26,27)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148945 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-m...) Show SMILES COc1cccc(COc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C26H29N5O4/c1-17(19-8-12-22(13-9-19)35-16-18-4-3-5-23(14-18)34-2)30-24(32)15-29-26(33)31-21-10-6-20(7-11-21)25(27)28/h3-14,17H,15-16H2,1-2H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148958 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-c...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(OCc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H26ClN5O3/c1-16(18-7-11-22(12-8-18)34-15-17-3-2-4-20(26)13-17)30-23(32)14-29-25(33)31-21-9-5-19(6-10-21)24(27)28/h2-13,16H,14-15H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148949 (CHEMBL339200 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2cccc(C)c2)cc1 Show InChI InChI=1S/C26H28N6O3/c1-16-4-3-5-20(14-16)25(34)31-21-10-6-18(7-11-21)17(2)30-23(33)15-29-26(35)32-22-12-8-19(9-13-22)24(27)28/h3-14,17H,15H2,1-2H3,(H3,27,28)(H,30,33)(H,31,34)(H2,29,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148960 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-nap...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23N5O2/c1-14(17-7-6-15-4-2-3-5-18(15)12-17)26-20(28)13-25-22(29)27-19-10-8-16(9-11-19)21(23)24/h2-12,14H,13H2,1H3,(H3,23,24)(H,26,28)(H2,25,27,29)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126571 (CHEMBL35586 | N-[(S)-1-(3-Bromo-phenyl)-ethyl]-2-[...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1cccc(Br)c1 Show InChI InChI=1S/C18H20BrN5O2/c1-11(13-3-2-4-14(19)9-13)23-16(25)10-22-18(26)24-15-7-5-12(6-8-15)17(20)21/h2-9,11H,10H2,1H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148954 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C23H27F3N6O3/c1-14(16-4-7-19(18(12-16)23(24,25)26)32-8-10-35-11-9-32)30-20(33)13-29-22(34)31-17-5-2-15(3-6-17)21(27)28/h2-7,12,14H,8-11,13H2,1H3,(H3,27,28)(H,30,33)(H2,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148961 (2-Benzyloxy-5-(1-{2-[3-(4-carbamimidoyl-phenyl)-ur...) Show SMILES COC(=O)c1cc(ccc1OCc1ccccc1)C(C)NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N Show InChI InChI=1S/C27H29N5O5/c1-17(31-24(33)15-30-27(35)32-21-11-8-19(9-12-21)25(28)29)20-10-13-23(22(14-20)26(34)36-2)37-16-18-6-4-3-5-7-18/h3-14,17H,15-16H2,1-2H3,(H3,28,29)(H,31,33)(H2,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148951 (CHEMBL330943 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H26N6O3/c1-16(17-7-11-20(12-8-17)30-24(33)19-5-3-2-4-6-19)29-22(32)15-28-25(34)31-21-13-9-18(10-14-21)23(26)27/h2-14,16H,15H2,1H3,(H3,26,27)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126579 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[(S)-1-(3-...) Show SMILES COc1cccc(c1)[C@H](C)NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N Show InChI InChI=1S/C19H23N5O3/c1-12(14-4-3-5-16(10-14)27-2)23-17(25)11-22-19(26)24-15-8-6-13(7-9-15)18(20)21/h3-10,12H,11H2,1-2H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148946 (4-(1-{2-[3-(4-Carbamimidoyl-phenyl)-ureido]-acetyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C31H30N6O4/c1-20(35-28(38)19-34-31(40)37-24-16-14-22(15-17-24)29(32)33)21-10-12-23(13-11-21)30(39)36-25-6-5-9-27(18-25)41-26-7-3-2-4-8-26/h2-18,20H,19H2,1H3,(H3,32,33)(H,35,38)(H,36,39)(H2,34,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148956 (CHEMBL123336 | Cyclopropanecarboxylic acid [4-(1-{...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)C2CC2)cc1 Show InChI InChI=1S/C22H26N6O3/c1-13(14-4-8-17(9-5-14)27-21(30)16-2-3-16)26-19(29)12-25-22(31)28-18-10-6-15(7-11-18)20(23)24/h4-11,13,16H,2-3,12H2,1H3,(H3,23,24)(H,26,29)(H,27,30)(H2,25,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148966 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(3,4-di...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H19Cl2N5O2/c1-10(12-4-7-14(19)15(20)8-12)24-16(26)9-23-18(27)25-13-5-2-11(3-6-13)17(21)22/h2-8,10H,9H2,1H3,(H3,21,22)(H,24,26)(H2,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148959 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H25N5O3/c1-16(17-9-13-21(14-10-17)32-20-5-3-2-4-6-20)28-22(30)15-27-24(31)29-19-11-7-18(8-12-19)23(25)26/h2-14,16H,15H2,1H3,(H3,25,26)(H,28,30)(H2,27,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148944 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(4-m...) Show SMILES COc1ccc(Oc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)cc1 Show InChI InChI=1S/C25H27N5O4/c1-16(17-5-9-21(10-6-17)34-22-13-11-20(33-2)12-14-22)29-23(31)15-28-25(32)30-19-7-3-18(4-8-19)24(26)27/h3-14,16H,15H2,1-2H3,(H3,26,27)(H,29,31)(H2,28,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148964 (CHEMBL121981 | N-[1-(4-Benzyloxy-phenyl)-ethyl]-2-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C25H27N5O3/c1-17(19-9-13-22(14-10-19)33-16-18-5-3-2-4-6-18)29-23(31)15-28-25(32)30-21-11-7-20(8-12-21)24(26)27/h2-14,17H,15-16H2,1H3,(H3,26,27)(H,29,31)(H2,28,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148955 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C22H28N6O3/c1-15(16-4-8-19(9-5-16)28-10-12-31-13-11-28)26-20(29)14-25-22(30)27-18-6-2-17(3-7-18)21(23)24/h2-9,15H,10-14H2,1H3,(H3,23,24)(H,26,29)(H2,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148957 (CHEMBL122765 | N-[1-((S)-4-Bromo-phenyl)-ethyl]-2-...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Br)cc1 Show InChI InChI=1S/C18H20BrN5O2/c1-11(12-2-6-14(19)7-3-12)23-16(25)10-22-18(26)24-15-8-4-13(5-9-15)17(20)21/h2-9,11H,10H2,1H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148965 (CHEMBL122151 | N-[1-(4-Benzyl-phenyl)-ethyl]-2-[3-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C25H27N5O2/c1-17(20-9-7-19(8-10-20)15-18-5-3-2-4-6-18)29-23(31)16-28-25(32)30-22-13-11-21(12-14-22)24(26)27/h2-14,17H,15-16H2,1H3,(H3,26,27)(H,29,31)(H2,28,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148948 (CHEMBL122863 | N-[1-(4-Acetylamino-phenyl)-ethyl]-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C20H24N6O3/c1-12(14-3-7-16(8-4-14)25-13(2)27)24-18(28)11-23-20(29)26-17-9-5-15(6-10-17)19(21)22/h3-10,12H,11H2,1-2H3,(H3,21,22)(H,24,28)(H,25,27)(H2,23,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	196	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148943 (CHEMBL338641 | N-[1-(3-Benzyloxy-phenyl)-1-methyl-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C25H27N5O3/c1-17(20-8-5-9-22(14-20)33-16-18-6-3-2-4-7-18)29-23(31)15-28-25(32)30-21-12-10-19(11-13-21)24(26)27/h2-14,17H,15-16H2,1H3,(H3,26,27)(H,29,31)(H2,28,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126585 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-phe...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccccc1 Show InChI InChI=1S/C18H21N5O2/c1-12(13-5-3-2-4-6-13)22-16(24)11-21-18(25)23-15-9-7-14(8-10-15)17(19)20/h2-10,12H,11H2,1H3,(H3,19,20)(H,22,24)(H2,21,23,25)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148963 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(2,4...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C24H23Cl2N5O3/c1-14(15-4-9-19(10-5-15)34-21-11-6-17(25)12-20(21)26)30-22(32)13-29-24(33)31-18-7-2-16(3-8-18)23(27)28/h2-12,14H,13H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	483	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148961 (2-Benzyloxy-5-(1-{2-[3-(4-carbamimidoyl-phenyl)-ur...) Show SMILES COC(=O)c1cc(ccc1OCc1ccccc1)C(C)NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N Show InChI InChI=1S/C27H29N5O5/c1-17(31-24(33)15-30-27(35)32-21-11-8-19(9-12-21)25(28)29)20-10-13-23(22(14-20)26(34)36-2)37-16-18-6-4-3-5-7-18/h3-14,17H,15-16H2,1-2H3,(H3,28,29)(H,31,33)(H2,30,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148950 (CHEMBL332753 | N-[1-(3-Bromo-4-morpholin-4-yl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(Br)c1 Show InChI InChI=1S/C22H27BrN6O3/c1-14(16-4-7-19(18(23)12-16)29-8-10-32-11-9-29)27-20(30)13-26-22(31)28-17-5-2-15(3-6-17)21(24)25/h2-7,12,14H,8-11,13H2,1H3,(H3,24,25)(H,27,30)(H2,26,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126582 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-(3,4-dichl...) Show SMILES NC(=N)c1ccc(NC(=O)NCC(=O)NCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C17H17Cl2N5O2/c18-13-6-1-10(7-14(13)19)8-22-15(25)9-23-17(26)24-12-4-2-11(3-5-12)16(20)21/h1-7H,8-9H2,(H3,20,21)(H,22,25)(H2,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148954 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C23H27F3N6O3/c1-14(16-4-7-19(18(12-16)23(24,25)26)32-8-10-35-11-9-32)30-20(33)13-29-22(34)31-17-5-2-15(3-6-17)21(27)28/h2-7,12,14H,8-11,13H2,1H3,(H3,27,28)(H,30,33)(H2,29,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148958 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-c...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(OCc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H26ClN5O3/c1-16(18-7-11-22(12-8-18)34-15-17-3-2-4-20(26)13-17)30-23(32)14-29-25(33)31-21-9-5-19(6-10-21)24(27)28/h2-13,16H,14-15H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148945 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-m...) Show SMILES COc1cccc(COc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C26H29N5O4/c1-17(19-8-12-22(13-9-19)35-16-18-4-3-5-23(14-18)34-2)30-24(32)15-29-26(33)31-21-10-6-20(7-11-21)25(27)28/h3-14,17H,15-16H2,1-2H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148960 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-nap...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23N5O2/c1-14(17-7-6-15-4-2-3-5-18(15)12-17)26-20(28)13-25-22(29)27-19-10-8-16(9-11-19)21(23)24/h2-12,14H,13H2,1H3,(H3,23,24)(H,26,28)(H2,25,27,29)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148955 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C22H28N6O3/c1-15(16-4-8-19(9-5-16)28-10-12-31-13-11-28)26-20(29)14-25-22(30)27-18-6-2-17(3-7-18)21(23)24/h2-9,15H,10-14H2,1H3,(H3,23,24)(H,26,29)(H2,25,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148951 (CHEMBL330943 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H26N6O3/c1-16(17-7-11-20(12-8-17)30-24(33)19-5-3-2-4-6-19)29-22(32)15-28-25(34)31-21-13-9-18(10-14-21)23(26)27/h2-14,16H,15H2,1H3,(H3,26,27)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148960 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-nap...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23N5O2/c1-14(17-7-6-15-4-2-3-5-18(15)12-17)26-20(28)13-25-22(29)27-19-10-8-16(9-11-19)21(23)24/h2-12,14H,13H2,1H3,(H3,23,24)(H,26,28)(H2,25,27,29)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148957 (CHEMBL122765 | N-[1-((S)-4-Bromo-phenyl)-ethyl]-2-...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Br)cc1 Show InChI InChI=1S/C18H20BrN5O2/c1-11(12-2-6-14(19)7-3-12)23-16(25)10-22-18(26)24-15-8-4-13(5-9-15)17(20)21/h2-9,11H,10H2,1H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148962 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((R)-1-nap...) Show SMILES C[C@@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23N5O2/c1-14(17-7-6-15-4-2-3-5-18(15)12-17)26-20(28)13-25-22(29)27-19-10-8-16(9-11-19)21(23)24/h2-12,14H,13H2,1H3,(H3,23,24)(H,26,28)(H2,25,27,29)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148959 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H25N5O3/c1-16(17-9-13-21(14-10-17)32-20-5-3-2-4-6-20)28-22(30)15-27-24(31)29-19-11-7-18(8-12-19)23(25)26/h2-14,16H,15H2,1H3,(H3,25,26)(H,28,30)(H2,27,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50148944 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(4-m...) Show SMILES COc1ccc(Oc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)cc1 Show InChI InChI=1S/C25H27N5O4/c1-16(17-5-9-21(10-6-17)34-22-13-11-20(33-2)12-14-22)29-23(31)15-28-25(32)30-19-7-3-18(4-8-19)24(26)27/h3-14,16H,15H2,1-2H3,(H3,26,27)(H,29,31)(H2,28,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of thrombin				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148958 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-c...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(OCc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H26ClN5O3/c1-16(18-7-11-22(12-8-18)34-15-17-3-2-4-20(26)13-17)30-23(32)14-29-25(33)31-21-9-5-19(6-10-21)24(27)28/h2-13,16H,14-15H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148953 (4-(1-{2-[3-(4-Carbamimidoyl-phenyl)-ureido]-acetyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H26N6O3/c1-16(17-7-9-19(10-8-17)24(33)30-20-5-3-2-4-6-20)29-22(32)15-28-25(34)31-21-13-11-18(12-14-21)23(26)27/h2-14,16H,15H2,1H3,(H3,26,27)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148961 (2-Benzyloxy-5-(1-{2-[3-(4-carbamimidoyl-phenyl)-ur...) Show SMILES COC(=O)c1cc(ccc1OCc1ccccc1)C(C)NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N Show InChI InChI=1S/C27H29N5O5/c1-17(31-24(33)15-30-27(35)32-21-11-8-19(9-12-21)25(28)29)20-10-13-23(22(14-20)26(34)36-2)37-16-18-6-4-3-5-7-18/h3-14,17H,15-16H2,1-2H3,(H3,28,29)(H,31,33)(H2,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50126585 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-phe...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccccc1 Show InChI InChI=1S/C18H21N5O2/c1-12(13-5-3-2-4-6-13)22-16(24)11-21-18(25)23-15-9-7-14(8-10-15)17(19)20/h2-10,12H,11H2,1H3,(H3,19,20)(H,22,24)(H2,21,23,25)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148945 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-m...) Show SMILES COc1cccc(COc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C26H29N5O4/c1-17(19-8-12-22(13-9-19)35-16-18-4-3-5-23(14-18)34-2)30-24(32)15-29-26(33)31-21-10-6-20(7-11-21)25(27)28/h3-14,17H,15-16H2,1-2H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148959 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H25N5O3/c1-16(17-9-13-21(14-10-17)32-20-5-3-2-4-6-20)28-22(30)15-27-24(31)29-19-11-7-18(8-12-19)23(25)26/h2-14,16H,15H2,1H3,(H3,25,26)(H,28,30)(H2,27,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148946 (4-(1-{2-[3-(4-Carbamimidoyl-phenyl)-ureido]-acetyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)C(=O)Nc1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C31H30N6O4/c1-20(35-28(38)19-34-31(40)37-24-16-14-22(15-17-24)29(32)33)21-10-12-23(13-11-21)30(39)36-25-6-5-9-27(18-25)41-26-7-3-2-4-8-26/h2-18,20H,19H2,1H3,(H3,32,33)(H,35,38)(H,36,39)(H2,34,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148950 (CHEMBL332753 | N-[1-(3-Bromo-4-morpholin-4-yl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(Br)c1 Show InChI InChI=1S/C22H27BrN6O3/c1-14(16-4-7-19(18(23)12-16)29-8-10-32-11-9-29)27-20(30)13-26-22(31)28-17-5-2-15(3-6-17)21(24)25/h2-7,12,14H,8-11,13H2,1H3,(H3,24,25)(H,27,30)(H2,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148954 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C23H27F3N6O3/c1-14(16-4-7-19(18(12-16)23(24,25)26)32-8-10-35-11-9-32)30-20(33)13-29-22(34)31-17-5-2-15(3-6-17)21(27)28/h2-7,12,14H,8-11,13H2,1H3,(H3,27,28)(H,30,33)(H2,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50148949 (CHEMBL339200 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2cccc(C)c2)cc1 Show InChI InChI=1S/C26H28N6O3/c1-16-4-3-5-20(14-16)25(34)31-21-10-6-18(7-11-21)17(2)30-23(33)15-29-26(35)32-22-12-8-19(9-13-22)24(27)28/h3-14,17H,15H2,1-2H3,(H3,27,28)(H,30,33)(H,31,34)(H2,29,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor X				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair

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