Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 50045298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-2 (Rattus norvegicus)	BDBM50055861 (CHEMBL3329968) Show SMILES OC(=O)c1ccc(NC2=CC(=O)C(Nc3ccc(cc3)C(O)=O)=CC2=O)cc1 |c:23,t:8| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-7-3-12(4-8-14)20(27)28)18(24)9-15(17)21-13-5-1-11(2-6-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055860 (CHEMBL3329967) Show SMILES OC(=O)c1cccc(NC2=CC(=O)C(Nc3cccc(c3)C(O)=O)=CC2=O)c1 |c:24,t:9| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-6-2-4-12(8-14)20(27)28)18(24)9-15(17)21-13-5-1-3-11(7-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055859 (CHEMBL3329966) Show SMILES Oc1ccc(NC2=CC(=O)C(Nc3ccc(O)cc3)=CC2=O)cc1 |c:19,t:6| Show InChI InChI=1S/C18H14N2O4/c21-13-5-1-11(2-6-13)19-15-9-18(24)16(10-17(15)23)20-12-3-7-14(22)8-4-12/h1-10,19-22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50055859 (CHEMBL3329966) Show SMILES Oc1ccc(NC2=CC(=O)C(Nc3ccc(O)cc3)=CC2=O)cc1 |c:19,t:6| Show InChI InChI=1S/C18H14N2O4/c21-13-5-1-11(2-6-13)19-15-9-18(24)16(10-17(15)23)20-12-3-7-14(22)8-4-12/h1-10,19-22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055862 (CHEMBL3329969) Show SMILES Oc1cccc(NC2=CC(=O)C(Nc3cccc(O)c3)=CC2=O)c1 |c:20,t:7| Show InChI InChI=1S/C18H14N2O4/c21-13-5-1-3-11(7-13)19-15-9-18(24)16(10-17(15)23)20-12-4-2-6-14(22)8-12/h1-10,19-22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50055863 (CHEMBL2252571) Show SMILES O=C1C=C(NCc2ccccc2)C(=O)C=C1NCc1ccccc1 |c:15,t:2| Show InChI InChI=1S/C20H18N2O2/c23-19-12-18(22-14-16-9-5-2-6-10-16)20(24)11-17(19)21-13-15-7-3-1-4-8-15/h1-12,21-22H,13-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50266767 (2,2'-(3,6-dioxocyclohexa-1,4-diene-1,4-diyl)bis(az...) Show SMILES OC(=O)c1ccccc1NC1=CC(=O)C(Nc2ccccc2C(O)=O)=CC1=O |c:26,t:11| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-8-4-2-6-12(14)20(27)28)18(24)9-15(17)21-13-7-3-1-5-11(13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50055861 (CHEMBL3329968) Show SMILES OC(=O)c1ccc(NC2=CC(=O)C(Nc3ccc(cc3)C(O)=O)=CC2=O)cc1 |c:23,t:8| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-7-3-12(4-8-14)20(27)28)18(24)9-15(17)21-13-5-1-11(2-6-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-1 (Homo sapiens (Human))	BDBM50055860 (CHEMBL3329967) Show SMILES OC(=O)c1cccc(NC2=CC(=O)C(Nc3cccc(c3)C(O)=O)=CC2=O)c1 |c:24,t:9| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-6-2-4-12(8-14)20(27)28)18(24)9-15(17)21-13-5-1-3-11(7-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of Dynamin 1 in serum-starved human U2OS cells assessed as inhibition of clathrin-mediated Alexa-495-cojugated transferrin uptake pretreat...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair