BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50015622
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158458 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-dimethylphe...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(C)c(O)c(C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50158458 ((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-dimethylphe...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(C)c(O)c(C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158464 ((2-ethylbenzofuran-3-yl)(4-methoxy-3,5-dimethylphe...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(C)c(OC)c(C)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158470 (2,6-dibromo-4-((2-ethylbenzofuran-3-yl)(hydroxy)me...) Show SMILES CCc1oc2ccccc2c1C(O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158463 ((3,5-dibromo-4-methoxyphenyl)(2-ethylbenzofuran-3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158467 (2-(3,5-dibromo-4-hydroxyphenyl)-1-(2-ethylbenzofur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158469 ((3,5-dibromo-4-hydroxyphenyl)(2-methylbenzofuran-3...) Show SMILES Cc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158457 ((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...) Show SMILES Cc1oc2ccccc2c1C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158460 ((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158462 ((4-(dimethylamino)phenyl)(2-ethylbenzofuran-3-yl)m...) Show SMILES CCc1oc2ccccc2c1C(=O)c1ccc(cc1)N(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158466 ((4-methoxyphenyl)(2-methylbenzofuran-3-yl)methanon...) Show SMILES COc1ccc(cc1)C(=O)c1c(C)oc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158459 ((3-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...) Show SMILES Cc1oc2ccccc2c1C(=O)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158465 ((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...) Show SMILES Cc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158461 ((2,6-dichloropyridin-4-yl)(2-ethylbenzofuran-3-yl)...) Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Cl)nc(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50158468 (CHEMBL390613 \| cyclohexyl(2-methylbenzofuran-3-yl)...) Show SMILES Cc1oc2ccccc2c1C(=O)C1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington State University Curated by ChEMBL					Assay Description Inhibition of human CYP2C19				J Med Chem 47: 6768-76 (2004) Article DOI: 10.1021/jm049605m BindingDB Entry DOI: 10.7270/Q29P3153
Washington State University Curated by ChEMBL					More data for this Ligand-Target Pair