Compile Data Set for Download or QSAR

Found 62 hits Enz. Inhib. hit(s) with all data for entry = 50045407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061017 (CHEMBL3393547) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)n1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-5-7-21(10-13)15-4-6-18-16(20-15)19-14-9-11-2-3-12(14)8-11/h4,6,11-14,17H,2-3,5,7-10H2,1H3,(H,18,19,20)/t11?,12?,13-,14?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061098 (CHEMBL3393534 | US9732087, 1) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)c1 |r| Show InChI InChI=1S/C17H26N4/c1-18-14-5-7-21(11-14)15-4-6-19-17(10-15)20-16-9-12-2-3-13(16)8-12/h4,6,10,12-14,16,18H,2-3,5,7-9,11H2,1H3,(H,19,20)/t12?,13?,14-,16?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061143 (CHEMBL3393526 | US9732087, 22) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NCC(C)C)c1 |r| Show InChI InChI=1S/C14H24N4/c1-11(2)9-17-14-8-13(4-6-16-14)18-7-5-12(10-18)15-3/h4,6,8,11-12,15H,5,7,9-10H2,1-3H3,(H,16,17)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061020 (CHEMBL3393544) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CCCC2)n1 |r| Show InChI InChI=1S/C14H23N5/c1-15-12-7-9-19(10-12)13-6-8-16-14(18-13)17-11-4-2-3-5-11/h6,8,11-12,15H,2-5,7,9-10H2,1H3,(H,16,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061060 (CHEMBL3393539 | US9732087, 32) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NCC(C)C)n1 |r| Show InChI InChI=1S/C13H23N5/c1-10(2)8-16-13-15-6-4-12(17-13)18-7-5-11(9-18)14-3/h4,6,10-11,14H,5,7-9H2,1-3H3,(H,15,16,17)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061056 (CHEMBL3393542 | US9732087, 73) Show SMILES CCCCNc1nccc(n1)N1CC[C@H](C1)NC |r| Show InChI InChI=1S/C13H23N5/c1-3-4-7-15-13-16-8-5-12(17-13)18-9-6-11(10-18)14-2/h5,8,11,14H,3-4,6-7,9-10H2,1-2H3,(H,15,16,17)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061138 (CHEMBL3393532) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CCCC2)c1 |r| Show InChI InChI=1S/C15H24N4/c1-16-13-7-9-19(11-13)14-6-8-17-15(10-14)18-12-4-2-3-5-12/h6,8,10,12-13,16H,2-5,7,9,11H2,1H3,(H,17,18)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061007 (CHEMBL3393557) Show SMILES CN[C@H]1CCN(C1)c1cnnc(NC2CC3CCC2C3)c1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-4-5-21(10-13)14-8-16(20-18-9-14)19-15-7-11-2-3-12(15)6-11/h8-9,11-13,15,17H,2-7,10H2,1H3,(H,19,20)/t11?,12?,13-,15?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061071 (CHEMBL3393535) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)c1 |r| Show InChI InChI=1S/C17H26N4/c1-18-14-5-7-21(11-14)15-4-6-19-17(10-15)20-16-9-12-2-3-13(16)8-12/h4,6,10,12-14,16,18H,2-3,5,7-9,11H2,1H3,(H,19,20)/t12?,13?,14-,16?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061011 (CHEMBL3393553) Show SMILES CN[C@@H]1CCN(C1)c1cnnc(NC2CCCC2)c1 |r| Show InChI InChI=1S/C14H23N5/c1-15-12-6-7-19(10-12)13-8-14(18-16-9-13)17-11-4-2-3-5-11/h8-9,11-12,15H,2-7,10H2,1H3,(H,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061006 (CHEMBL3393529) Show SMILES CCCCNc1cc(ccn1)N1CC[C@H](C1)NC |r| Show InChI InChI=1S/C14H24N4/c1-3-4-7-16-14-10-13(5-8-17-14)18-9-6-12(11-18)15-2/h5,8,10,12,15H,3-4,6-7,9,11H2,1-2H3,(H,16,17)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061016 (CHEMBL3393548) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)n1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-5-7-21(10-13)15-4-6-18-16(20-15)19-14-9-11-2-3-12(14)8-11/h4,6,11-14,17H,2-3,5,7-10H2,1H3,(H,18,19,20)/t11?,12?,13-,14?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061008 (CHEMBL3393556 | US9732087, 96) Show SMILES CN[C@@H]1CCN(C1)c1cnnc(NC2CC3CCC2C3)c1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-4-5-21(10-13)14-8-16(20-18-9-14)19-15-7-11-2-3-12(15)6-11/h8-9,11-13,15,17H,2-7,10H2,1H3,(H,19,20)/t11?,12?,13-,15?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50036706 (CHEMBL3354815) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC(C)C)n1 |r| Show InChI InChI=1S/C12H21N5/c1-9(2)15-12-14-6-4-11(16-12)17-7-5-10(8-17)13-3/h4,6,9-10,13H,5,7-8H2,1-3H3,(H,14,15,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356859 (CHEMBL1915048) Show SMILES CN[C@@H]1CCN(C1)c1nc(N)nc2c3cc(Cl)cnc3oc12 |r| Show InChI InChI=1S/C14H15ClN6O/c1-17-8-2-3-21(6-8)12-11-10(19-14(16)20-12)9-4-7(15)5-18-13(9)22-11/h4-5,8,17H,2-3,6H2,1H3,(H2,16,19,20)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50006789 (CHEMBL3236549) Show SMILES CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1 |r| Show InChI InChI=1S/C11H19N5/c1-7(2)9-5-10(15-11(13)14-9)16-4-3-8(12)6-16/h5,7-8H,3-4,6,12H2,1-2H3,(H2,13,14,15)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061139 (CHEMBL3393531) Show SMILES CN1CCN(CC1)c1ccnc(NC2CCCC2)c1 Show InChI InChI=1S/C15H24N4/c1-18-8-10-19(11-9-18)14-6-7-16-15(12-14)17-13-4-2-3-5-13/h6-7,12-13H,2-5,8-11H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50036705 (CHEMBL3354816) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC(C)C)c1 |r| Show InChI InChI=1S/C13H22N4/c1-10(2)16-13-8-12(4-6-15-13)17-7-5-11(9-17)14-3/h4,6,8,10-11,14H,5,7,9H2,1-3H3,(H,15,16)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061148 (CHEMBL3393521) Show SMILES CN1CCN(CC1)c1ccnc(c1)-c1ccsc1 Show InChI InChI=1S/C14H17N3S/c1-16-5-7-17(8-6-16)13-2-4-15-14(10-13)12-3-9-18-11-12/h2-4,9-11H,5-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061126 (CHEMBL3393533) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC2CCCC2)c1 |r| Show InChI InChI=1S/C15H24N4/c1-16-13-7-9-19(11-13)14-6-8-17-15(10-14)18-12-4-2-3-5-12/h6,8,10,12-13,16H,2-5,7,9,11H2,1H3,(H,17,18)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061019 (CHEMBL3393545) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC2CCCC2)n1 |r| Show InChI InChI=1S/C14H23N5/c1-15-12-7-9-19(10-12)13-6-8-16-14(18-13)17-11-4-2-3-5-11/h6,8,11-12,15H,2-5,7,9-10H2,1H3,(H,16,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061144 (CHEMBL3393525 | US9732087, 21) Show SMILES CC(C)CNc1cc(ccn1)N1CCN(C)CC1 Show InChI InChI=1S/C14H24N4/c1-12(2)11-16-14-10-13(4-5-15-14)18-8-6-17(3)7-9-18/h4-5,10,12H,6-9,11H2,1-3H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061057 (CHEMBL3393541) Show SMILES CCCCNc1nccc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-3-4-6-14-13-15-7-5-12(16-13)18-10-8-17(2)9-11-18/h5,7H,3-4,6,8-11H2,1-2H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061014 (CHEMBL3393550 | US9732087, 95) Show SMILES CN[C@@H]1CCN(C1)c1cnnc(NCC(C)C)c1 |r| Show InChI InChI=1S/C13H23N5/c1-10(2)7-15-13-6-12(8-16-17-13)18-5-4-11(9-18)14-3/h6,8,10-11,14H,4-5,7,9H2,1-3H3,(H,15,17)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061021 (CHEMBL3393543) Show SMILES CN1CCN(CC1)c1ccnc(NC2CCCC2)n1 Show InChI InChI=1S/C14H23N5/c1-18-8-10-19(11-9-18)13-6-7-15-14(17-13)16-12-4-2-3-5-12/h6-7,12H,2-5,8-11H2,1H3,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061065 (CHEMBL3393538 | US9732087, 31) Show SMILES CC(C)CNc1nccc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-11(2)10-15-13-14-5-4-12(16-13)18-8-6-17(3)7-9-18/h4-5,11H,6-10H2,1-3H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061018 (CHEMBL3393546 | US9732087, 44) Show SMILES CN1CCN(CC1)c1ccnc(NC2CC3CCC2C3)n1 Show InChI InChI=1S/C16H25N5/c1-20-6-8-21(9-7-20)15-4-5-17-16(19-15)18-14-11-12-2-3-13(14)10-12/h4-5,12-14H,2-3,6-11H2,1H3,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061142 (CHEMBL3393527 | US9732087, 15) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NCC(C)C)c1 |r| Show InChI InChI=1S/C14H24N4/c1-11(2)9-17-14-8-13(4-6-16-14)18-7-5-12(10-18)15-3/h4,6,8,11-12,15H,5,7,9-10H2,1-3H3,(H,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061145 (CHEMBL3393524) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(c1)N1CCCCC1 |r| Show InChI InChI=1S/C15H24N4/c1-16-13-6-10-19(12-13)14-5-7-17-15(11-14)18-8-3-2-4-9-18/h5,7,11,13,16H,2-4,6,8-10,12H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061140 (CHEMBL3393530) Show SMILES CCCCNc1cc(ccn1)N1CC[C@@H](C1)NC |r| Show InChI InChI=1S/C14H24N4/c1-3-4-7-16-14-10-13(5-8-17-14)18-9-6-12(11-18)15-2/h5,8,10,12,15H,3-4,6-7,9,11H2,1-2H3,(H,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061070 (CHEMBL3393536 | US9732087, 53) Show SMILES CC(C)Nc1nccc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C12H21N5/c1-10(2)14-12-13-5-4-11(15-12)17-8-6-16(3)7-9-17/h4-5,10H,6-9H2,1-3H3,(H,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061068 (CHEMBL3393537) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC(C)C)n1 |r| Show InChI InChI=1S/C12H21N5/c1-9(2)15-12-14-6-4-11(16-12)17-7-5-10(8-17)13-3/h4,6,9-10,13H,5,7-8H2,1-3H3,(H,14,15,16)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061059 (CHEMBL3393540) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NCC(C)C)n1 |r| Show InChI InChI=1S/C13H23N5/c1-10(2)8-16-13-15-6-4-12(17-13)18-7-5-11(9-18)14-3/h4,6,10-11,14H,5,7-9H2,1-3H3,(H,15,16,17)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061146 (CHEMBL3393523) Show SMILES CN1CCN(CC1)c1ccnc(c1)N1CCCCC1 Show InChI InChI=1S/C15H24N4/c1-17-9-11-18(12-10-17)14-5-6-16-15(13-14)19-7-3-2-4-8-19/h5-6,13H,2-4,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061141 (CHEMBL3393528) Show SMILES CCCCNc1cc(ccn1)N1CCN(C)CC1 Show InChI InChI=1S/C14H24N4/c1-3-4-6-15-14-12-13(5-7-16-14)18-10-8-17(2)9-11-18/h5,7,12H,3-4,6,8-11H2,1-2H3,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061147 (CHEMBL3393522) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(c1)-c1ccsc1 |r| Show InChI InChI=1S/C14H17N3S/c1-15-12-3-6-17(9-12)13-2-5-16-14(8-13)11-4-7-18-10-11/h2,4-5,7-8,10,12,15H,3,6,9H2,1H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061010 (CHEMBL3393554) Show SMILES CN[C@H]1CCN(C1)c1cnnc(NC2CCCC2)c1 |r| Show InChI InChI=1S/C14H23N5/c1-15-12-6-7-19(10-12)13-8-14(18-16-9-13)17-11-4-2-3-5-11/h8-9,11-12,15H,2-7,10H2,1H3,(H,17,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061009 (CHEMBL3393555) Show SMILES CN1CCN(CC1)c1cnnc(NC2CC3CCC2C3)c1 Show InChI InChI=1S/C16H25N5/c1-20-4-6-21(7-5-20)14-10-16(19-17-11-14)18-15-9-12-2-3-13(15)8-12/h10-13,15H,2-9H2,1H3,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	365	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061013 (CHEMBL3393551) Show SMILES CN[C@H]1CCN(C1)c1cnnc(NCC(C)C)c1 |r| Show InChI InChI=1S/C13H23N5/c1-10(2)7-15-13-6-12(8-16-17-13)18-5-4-11(9-18)14-3/h6,8,10-11,14H,4-5,7,9H2,1-3H3,(H,15,17)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	389	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061012 (CHEMBL3393552) Show SMILES CN1CCN(CC1)c1cnnc(NC2CCCC2)c1 Show InChI InChI=1S/C14H23N5/c1-18-6-8-19(9-7-18)13-10-14(17-15-11-13)16-12-4-2-3-5-12/h10-12H,2-9H2,1H3,(H,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	824	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061015 (CHEMBL3393549 | US9732087, 101) Show SMILES CC(C)CNc1cc(cnn1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-11(2)9-14-13-8-12(10-15-16-13)18-6-4-17(3)5-7-18/h8,10-11H,4-7,9H2,1-3H3,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50036706 (CHEMBL3354815) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC(C)C)n1 |r| Show InChI InChI=1S/C12H21N5/c1-9(2)15-12-14-6-4-11(16-12)17-7-5-10(8-17)13-3/h4,6,9-10,13H,5,7-8H2,1-3H3,(H,14,15,16)/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061057 (CHEMBL3393541) Show SMILES CCCCNc1nccc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-3-4-6-14-13-15-7-5-12(16-13)18-10-8-17(2)9-11-18/h5,7H,3-4,6,8-11H2,1-2H3,(H,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061056 (CHEMBL3393542 | US9732087, 73) Show SMILES CCCCNc1nccc(n1)N1CC[C@H](C1)NC |r| Show InChI InChI=1S/C13H23N5/c1-3-4-7-15-13-16-8-5-12(17-13)18-9-6-11(10-18)14-2/h5,8,11,14H,3-4,6-7,9-10H2,1-2H3,(H,15,16,17)/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061021 (CHEMBL3393543) Show SMILES CN1CCN(CC1)c1ccnc(NC2CCCC2)n1 Show InChI InChI=1S/C14H23N5/c1-18-8-10-19(11-9-18)13-6-7-15-14(17-13)16-12-4-2-3-5-12/h6-7,12H,2-5,8-11H2,1H3,(H,15,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061020 (CHEMBL3393544) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CCCC2)n1 |r| Show InChI InChI=1S/C14H23N5/c1-15-12-7-9-19(10-12)13-6-8-16-14(18-13)17-11-4-2-3-5-11/h6,8,11-12,15H,2-5,7,9-10H2,1H3,(H,16,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061018 (CHEMBL3393546 | US9732087, 44) Show SMILES CN1CCN(CC1)c1ccnc(NC2CC3CCC2C3)n1 Show InChI InChI=1S/C16H25N5/c1-20-6-8-21(9-7-20)15-4-5-17-16(19-15)18-14-11-12-2-3-13(14)10-12/h4-5,12-14H,2-3,6-11H2,1H3,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061017 (CHEMBL3393547) Show SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)n1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-5-7-21(10-13)15-4-6-18-16(20-15)19-14-9-11-2-3-12(14)8-11/h4,6,11-14,17H,2-3,5,7-10H2,1H3,(H,18,19,20)/t11?,12?,13-,14?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50061016 (CHEMBL3393548) Show SMILES CN[C@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)n1 |r| Show InChI InChI=1S/C16H25N5/c1-17-13-5-7-21(10-13)15-4-6-18-16(20-15)19-14-9-11-2-3-12(14)8-11/h4,6,11-14,17H,2-3,5,7-10H2,1H3,(H,18,19,20)/t11?,12?,13-,14?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development, LLC Curated by ChEMBL					Assay Description Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...				Bioorg Med Chem Lett 25: 956-9 (2015) Article DOI: 10.1016/j.bmcl.2014.12.027 BindingDB Entry DOI: 10.7270/Q2639RDD
					More data for this Ligand-Target Pair

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