Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 50016216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166441 ((R)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-am...) Show SMILES COc1cccc(c1Cl)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C27H22ClF4N3O3/c1-38-23-12-5-9-17(24(23)28)18-13-34(14-19-20(27(30,31)32)10-6-11-21(19)29)26(37)35(25(18)36)15-22(33)16-7-3-2-4-8-16/h2-13,22H,14-15,33H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50162007 ((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r,wD:26.28,(6.65,3.5,;5.31,2.74,;3.98,3.51,;3.98,5.05,;2.64,5.83,;1.31,5.06,;1.31,3.52,;2.64,2.75,;2.64,1.21,;-.02,2.76,;-.02,1.22,;1.3,.46,;-1.35,.46,;-1.35,-1.08,;-.01,-1.85,;1.31,-1.08,;2.64,-.3,;2.64,-1.85,;2.65,-3.39,;1.31,-4.16,;-.02,-3.39,;-1.36,-4.16,;-2.68,1.22,;-4.01,.45,;-2.68,2.76,;-4.01,3.53,;-5.34,2.75,;-5.34,1.21,;-6.68,3.52,;-6.68,5.06,;-8.02,5.83,;-9.36,5.04,;-9.35,3.51,;-8.01,2.75,;-1.35,3.54,;-1.35,5.08,)| Show InChI InChI=1S/C27H24F3N3O3/c1-16-24(18-10-6-13-23(36-2)25(18)30)26(34)33(15-22(31)17-8-4-3-5-9-17)27(35)32(16)14-19-20(28)11-7-12-21(19)29/h3-13,22H,14-15,31H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166450 ((R)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-am...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C27H22F5N3O3/c1-38-23-12-5-9-17(24(23)29)18-13-34(14-19-20(27(30,31)32)10-6-11-21(19)28)26(37)35(25(18)36)15-22(33)16-7-3-2-4-8-16/h2-13,22H,14-15,33H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166451 ((R)-1-(2-fluoro-6-(methylsulfonyl)benzyl)-3-(2-ami...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2S(C)(=O)=O)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C27H25F2N3O5S/c1-37-23-12-6-10-18(25(23)29)19-14-31(15-20-21(28)11-7-13-24(20)38(2,35)36)27(34)32(26(19)33)16-22(30)17-8-4-3-5-9-17/h3-14,22H,15-16,30H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166437 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-chloro-3-metho...) Show SMILES COc1cccc(c1Cl)-c1cn(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C26H22ClF2N3O3/c1-35-23-12-5-9-17(24(23)27)18-13-31(14-19-20(28)10-6-11-21(19)29)26(34)32(25(18)33)15-22(30)16-7-3-2-4-8-16/h2-13,22H,14-15,30H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166458 ((R)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-am...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccccc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C26H20ClF4N3O2/c27-21-11-5-4-9-17(21)18-13-33(14-19-20(26(29,30)31)10-6-12-22(19)28)25(36)34(24(18)35)15-23(32)16-7-2-1-3-8-16/h1-13,23H,14-15,32H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166452 ((R)-1-(2-fluoro-6-(methylsulfonyl)benzyl)-3-(2-ami...) Show SMILES CS(=O)(=O)c1cccc(F)c1Cn1cc(-c2ccccc2Cl)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C26H23ClFN3O4S/c1-36(34,35)24-13-7-12-22(28)20(24)15-30-14-19(18-10-5-6-11-21(18)27)25(32)31(26(30)33)16-23(29)17-8-3-2-4-9-17/h2-14,23H,15-16,29H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166442 (3-((R)-2-Amino-2-phenyl-ethyl)-1-(2-chloro-6-fluor...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2Cl)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C26H22ClF2N3O3/c1-35-23-12-5-9-17(24(23)29)18-13-31(14-19-20(27)10-6-11-21(19)28)26(34)32(25(18)33)15-22(30)16-7-3-2-4-8-16/h2-13,22H,14-15,30H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166461 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(3-ethoxy-2-fluor...) Show SMILES CCOc1cccc(c1F)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C28H24F5N3O3/c1-2-39-24-13-6-10-18(25(24)30)19-14-35(15-20-21(28(31,32)33)11-7-12-22(20)29)27(38)36(26(19)37)16-23(34)17-8-4-3-5-9-17/h3-14,23H,2,15-16,34H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166443 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-chloro-4-methy...) Show SMILES Cc1ccc(c(Cl)c1)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C27H22ClF4N3O2/c1-16-10-11-18(22(28)12-16)19-13-34(14-20-21(27(30,31)32)8-5-9-23(20)29)26(37)35(25(19)36)15-24(33)17-6-3-2-4-7-17/h2-13,24H,14-15,33H2,1H3/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166459 (3-((R)-2-Amino-2-phenyl-ethyl)-1-(2-fluoro-6-trifl...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccccc1C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C27H20F7N3O2/c28-22-12-6-11-21(27(32,33)34)19(22)14-36-13-18(17-9-4-5-10-20(17)26(29,30)31)24(38)37(25(36)39)15-23(35)16-7-2-1-3-8-16/h1-13,23H,14-15,35H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166436 ((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r| Show InChI InChI=1S/C26H22F3N3O3/c1-35-23-12-5-9-17(24(23)29)18-13-31(14-19-20(27)10-6-11-21(19)28)26(34)32(25(18)33)15-22(30)16-7-3-2-4-8-16/h2-13,22H,14-15,30H2,1H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166448 ((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2F)c1=O)-c1ccccc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C25H20ClF2N3O2/c26-20-10-5-4-9-17(20)18-13-30(14-19-21(27)11-6-12-22(19)28)25(33)31(24(18)32)15-23(29)16-7-2-1-3-8-16/h1-13,23H,14-15,29H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166447 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-isopr...) Show SMILES CC(C)Oc1cccc(c1F)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C29H26F5N3O3/c1-17(2)40-25-13-6-10-19(26(25)31)20-14-36(15-21-22(29(32,33)34)11-7-12-23(21)30)28(39)37(27(20)38)16-24(35)18-8-4-3-5-9-18/h3-14,17,24H,15-16,35H2,1-2H3/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166456 ((R)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-am...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H21F4N3O2/c27-22-13-7-12-21(26(28,29)30)20(22)15-32-14-19(17-8-3-1-4-9-17)24(34)33(25(32)35)16-23(31)18-10-5-2-6-11-18/h1-14,23H,15-16,31H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166457 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-phenyl)...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccccc1F)c1ccccc1 Show InChI InChI=1S/C26H20F5N3O2/c27-21-11-5-4-9-17(21)18-13-33(14-19-20(26(29,30)31)10-6-12-22(19)28)25(36)34(24(18)35)15-23(32)16-7-2-1-3-8-16/h1-13,23H,14-15,32H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166454 (3-((R)-2-Amino-2-phenyl-ethyl)-5-[2-fluoro-3-(2,2,...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1cccc(OCC(F)(F)F)c1F)c1ccccc1 Show InChI InChI=1S/C28H21F8N3O3/c29-21-10-5-9-20(28(34,35)36)19(21)13-38-12-18(17-8-4-11-23(24(17)30)42-15-27(31,32)33)25(40)39(26(38)41)14-22(37)16-6-2-1-3-7-16/h1-12,22H,13-15,37H2/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166462 (3-((R)-2-Amino-2-phenyl-ethyl)-1-[2-fluoro-6-(2-hy...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2S(=O)(=O)CCO)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C28H27F2N3O6S/c1-39-24-11-5-9-19(26(24)30)20-15-32(16-21-22(29)10-6-12-25(21)40(37,38)14-13-34)28(36)33(27(20)35)17-23(31)18-7-3-2-4-8-18/h2-12,15,23,34H,13-14,16-17,31H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166446 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-hydro...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1cccc(O)c1F)c1ccccc1 Show InChI InChI=1S/C26H20F5N3O3/c27-20-10-5-9-19(26(29,30)31)18(20)13-33-12-17(16-8-4-11-22(35)23(16)28)24(36)34(25(33)37)14-21(32)15-6-2-1-3-7-15/h1-12,21,35H,13-14,32H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166445 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-metho...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2SC)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C27H25F2N3O3S/c1-35-23-12-6-10-18(25(23)29)19-14-31(15-20-21(28)11-7-13-24(20)36-2)27(34)32(26(19)33)16-22(30)17-8-4-3-5-9-17/h3-14,22H,15-16,30H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166444 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-metho...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2S(=O)(=O)C(C)C)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C29H29F2N3O5S/c1-18(2)40(37,38)26-14-8-12-23(30)22(26)16-33-15-21(20-11-7-13-25(39-3)27(20)31)28(35)34(29(33)36)17-24(32)19-9-5-4-6-10-19/h4-15,18,24H,16-17,32H2,1-3H3/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166453 (3-((S)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-metho...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C27H22F5N3O3/c1-38-23-12-5-9-17(24(23)29)18-13-34(14-19-20(27(30,31)32)10-6-11-21(19)28)26(37)35(25(18)36)15-22(33)16-7-3-2-4-8-16/h2-13,22H,14-15,33H2,1H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166449 (2-[3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-me...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2S(=O)(=O)N(C)C)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C28H28F2N4O5S/c1-32(2)40(37,38)25-14-8-12-22(29)21(25)16-33-15-20(19-11-7-13-24(39-3)26(19)30)27(35)34(28(33)36)17-23(31)18-9-5-4-6-10-18/h4-15,23H,16-17,31H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166460 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-chloro-4-trifl...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccc(cc1Cl)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C27H19ClF7N3O2/c28-21-11-16(26(30,31)32)9-10-17(21)18-12-37(13-19-20(27(33,34)35)7-4-8-22(19)29)25(40)38(24(18)39)14-23(36)15-5-2-1-3-6-15/h1-12,23H,13-14,36H2/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166439 (3-((S)-2-Amino-2-phenyl-ethyl)-1-(2,6-difluoro-ben...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2F)c(=O)n(C[C@@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C26H22F3N3O3/c1-35-23-12-5-9-17(24(23)29)18-13-31(14-19-20(27)10-6-11-21(19)28)26(34)32(25(18)33)15-22(30)16-7-3-2-4-8-16/h2-13,22H,14-15,30H2,1H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166455 (3-((R)-2-Amino-2-phenyl-ethyl)-1-(2,6-difluoro-ben...) Show SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2F)c1=O)-c1cccc(O)c1F)c1ccccc1 Show InChI InChI=1S/C25H20F3N3O3/c26-19-9-5-10-20(27)18(19)13-30-12-17(16-8-4-11-22(32)23(16)28)24(33)31(25(30)34)14-21(29)15-6-2-1-3-7-15/h1-12,21,32H,13-14,29H2/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166438 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-metho...) Show SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2S(=O)(=O)N2CCOCC2)c(=O)n(C[C@H](N)c2ccccc2)c1=O Show InChI InChI=1S/C30H30F2N4O6S/c1-41-26-11-5-9-21(28(26)32)22-17-34(30(38)36(29(22)37)19-25(33)20-7-3-2-4-8-20)18-23-24(31)10-6-12-27(23)43(39,40)35-13-15-42-16-14-35/h2-12,17,25H,13-16,18-19,33H2,1H3/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50166440 (3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-chloro-phenyl)...) Show SMILES CS(=O)(=O)c1cccc(c1Cn1cc(-c2ccccc2Cl)c(=O)n(C[C@H](N)c2ccccc2)c1=O)C(F)(F)F Show InChI InChI=1S/C27H23ClF3N3O4S/c1-39(37,38)24-13-7-11-21(27(29,30)31)20(24)15-33-14-19(18-10-5-6-12-22(18)28)25(35)34(26(33)36)16-23(32)17-8-3-2-4-9-17/h2-14,23H,15-16,32H2,1H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligand				Bioorg Med Chem Lett 15: 2519-22 (2005) Article DOI: 10.1016/j.bmcl.2005.03.057 BindingDB Entry DOI: 10.7270/Q2M044ZX
					More data for this Ligand-Target Pair