Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170306 (1-(2,2-Dimethyl-propyl)-4-propyl-5-[4'-(1H-tetrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 318 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170327 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{5-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170308 (1-(2,2-Dimethyl-propyl)-5-{4-[4-(1H-tetrazol-5-yl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.59E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170309 (1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 134 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170310 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 984 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170312 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 936 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 expressed in HEK293 cells done for 1 ... | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170311 (1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-b...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 652 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170313 (4-Bromo-1-(2,2-dimethyl-propyl)-5-{4-[4-(1H-tetraz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.26E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170314 (1-(2,2-Dimethyl-propyl)-4-methyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170315 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170317 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 451 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170316 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 879 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170319 (1-Pentyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-pheno...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 598 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170318 (1-(2,2-Dimethyl-propyl)-2-methyl-4-propyl-5-{4-[4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 559 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170320 (1-Isopropyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170321 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 779 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50153757 (1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 348 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170322 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 6.37E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170323 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{2-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170312 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 188 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170325 (1-Cyclopropylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 755 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170324 (1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 228 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170328 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170329 (1-Isobutyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 765 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170326 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 559 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50170307 (3-(2,2-Dimethyl-propyl)-7-propyl-6-{4-[4-(1H-tetra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 788 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr | Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K | |||||||||||
More data for this Ligand-Target Pair |